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PROSITE entry PS51504


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PURL: https://purl.expasy.org/prosite/signature/PS51504

Direct ScanProsite submission
General information about the entry

Entry name [info] H15
Accession [info] PS51504
Entry type [info] MATRIX
Date [info] 01-JUL-2010 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51504
Associated ProRule [info] PRU00837

Name and characterization of the entry

Description [info] Linker histone H1/H5 globular (H15) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=73;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=73;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1323326; R2=0.0084606; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=7660.1591797; R2=2.9217172; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1120; H_SCORE=10932; N_SCORE=11.6; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=517; H_SCORE=9171; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-48; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 160 in 148 different sequences
Number of true positive hits 160 in 148 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.38 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 3
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] H15
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
148 sequences

B4_XENLA(P15308), H101_CHICK  (P08284), H103_CHICK  (P08285), 
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UniProtKB/Swiss-Prot
False negative sequences
1 sequence

HILS1_MOUSE (Q9QYL0)

		
PDB
[Detailed view]
63 PDB

1GHC; 1HST; 1UHM; 1USS; 1UST; 1YQA; 2LSO; 2RQP; 4QLC; 5NL0; 5WCU; 6HQ1;
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