PROSITE entry PS51502

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51502
Entry name [info]	S_R_A_B_BARREL
Accession [info]	PS51502
Entry type [info]	MATRIX
Date [info]	01-AUG-2010 CREATED; 13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51502
Associated ProRule [info]	PRU00835

Name and characterization of the entry

Description [info]

Stress-response A/B barrel domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=95;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=90;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.5244322; R2=0.0074677; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=13160.9541016; R2=3.6318021; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1002; H_SCORE=16800; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=533; H_SCORE=15097; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-38; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='I';  M= -20,-123,-133, -79,  18, -87,-129,  75, -76,  16, -20,-127,-128, -86,-127,-120, -83,  52,-123, -38;
/M: SY='R';  M= -66, -31, -37,  19, -46, -47,  18,  -5,  33, -25,  -7, -22,-120,   9,  52, -68,  12, -13, -28,  23;
/M: SY='H';  M=-119,-132,-106,-104, -47,-122, 140,-135, -69, -98,-107, -31, -68, -20,  46, -80,-117,-133,-145, -92;
/M: SY='I';  M= -18,  18,-129,-126, -58, -91, -15,  75,-123,  -5,   9, -48,-125, -38,-126, -37,  -1,  47,-129, -63;
/M: SY='V';  M= -24,  -7,-129,-125, -42, -86,-130,  -2,-123,  -6, -94, -73,-127,-124,-125, -55,  20,  90,-134,-111;
/M: SY='M';  M= -52,  -1,-131,-125,  58, -87, -39,  -1,-122,  58,  69,-124,-129, -44, -41, -58, -34, -18, -41, -18;
/M: SY='F';  M= -19, -23,-135,-129,  94, -72, -30,  17,-126,  20,  -6,-126,-131, -65,-125,-121,-114,   6,  65, -45;
/M: SY='K';  M= -44, -56,-107, -32,-123, -97, -53, -82,  80,-124,-115,   1, -86,   7,  46,   9,  26,-120,  44, -53;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='F';  M= -25,-121,-133,-127,  77,-130,-121,   2,-125,  45,  -6,-127, -48,-125,-125, -55, -29,  21,  62, -20;
/M: SY='K';  M= -27,-127, -27, -20,-126, -89, -14, -38,  86, -75,-114,   3,  32, -39,  26, -26, -22,-120,-126, -64;
/M: SY='D';  M=  -6,-127,  60,  50,-131, -27, -14, -95,   5, -79,-120,   6,  53, -41, -39,   4, -25, -83,-134,-121;
/M: SY='D';  M= -10, -51,  48,  42, -38,  36, -34, -70, -39,-106,-120,  -6,  33,  -8, -27,   7,  -8, -81,-131, -87;
/I:         I=-18; MD=-45;
/M: SY='V';  M=  31, -63, -37, -58, -53, -37, -39,  -1, -45, -12, -49, -53,-130,-124,-128, -31,  27,  43,-139, -75; D=-18;
/I:         I=-18; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='T';  M= -27,-126,  11, -32,-131, -24, -29,-126,  -3,-106,-123, -13,   7, -68, -34,  49,  62, -63,-141,-125; D=-18;
/I:         I=-18; DM=-45;
/M: SY='P';  M=  20,-132,  42,  22, -95, -87,-117, -76, -16, -54, -39, -31,  46,  21, -10, -24,  -7, -59, -37,-125; D=-18;
/I:         I=-18; DM=-45;
/M: SY='E';  M=  31,-124,  31,  76, -44, -58, -65,-122, -25, -77,-117, -29, -38,  24, -27,  -7, -22, -35, -29,-118;
/M: SY='Q';  M= -11, -70,  44,  43, -53, -86,  24, -64, -29, -68, -23,  31, -39,  65,  -6, -27, -24,  -6, -40, -80;
/M: SY='I';  M=  -5, -47,-118, -12, -72, -42, -35,  48,  24,   3, -11, -71,-122,  -3,  31, -69, -26,  37,-126, -71;
/M: SY='E';  M=  28,-124,  42,  48, -70, -49, -14, -77,  11, -23, -17, -24, -31,  38,   1, -30, -10, -49,-129,-115;
/M: SY='E';  M=  34,-122,  14,  47, -36, -31, -36, -76,  24, -57, -38, -17, -58,  26,  17,  -2,   4, -51,-127,-115;
/M: SY='M';  M=  14,-119,-128, -71,  37, -78,  -3,  33, -53,  31,  45,-121, -80, -71, -80,-114, -17,  39,  22, -49;
/M: SY='M';  M= -16,  -4, -76,  13, -32, -68, -40,  22,  16,  35,  46, -66,-121,  -5,   8, -39, -29,  16,-123, -22;
/M: SY='E';  M=  26,-124,  48,  56,-129, -32, -14, -51,  20,-123,-117,  -4, -67,  30,  10,   2, -50, -78,-130,-117;
/M: SY='G';  M=  26,-122,  23,  13,-120,  33,-110, -15,  -4, -23,  15, -14, -54,  19,  -9,  13, -13, -59,-126, -24;
/M: SY='L';  M= -24,  15,-129,-124,  35, -37, -65,  17, -63,  64,  31,-123,-128, -65, -81, -93, -21, -21, -30,  23;
/M: SY='R';  M=   6, -73, -32,  39, -58, -14,  -7, -46,  13,  -6,  -3,  12,-117,  21,  44,   9, -40, -41, -29, -36;
/M: SY='A';  M=  47,-119,  20, -30,-125,   6, -15, -65,  20, -66,-114,   6,-115,  21,   7,  32,  12, -78,-129,-116;
/M: SY='L';  M= -42, -42, -80,-122, -17,-130, -64, -15,-121,  78,  72,-126,-129, -27, -71, -82, -58, -21,-119, -16;
/M: SY='K';  M=  24, -30, -72, -46, -80, -26,-112, -54,  57, -14, -73, -22,  43,  10,   7,   8, -28,   0,-125, -66;
/M: SY='D';  M=  19,-121,  37,   9, -81,  30,  12,-122,   1, -55,-115,  31, -53,   3, -14,  22,   2, -55,-129, -24;
/I:         I=-14; MD=-35;
/M: SY='K';  M= -15, -49, -15,  12, -85, -54,  22, -33,  40, -14, -48, -10,-122,  40, -12,  -4,   1,  -2,-133, -61; D=-14;
/I:         I=-14; MI=0; MD=-35; IM=0; DM=-35;
/M: SY='I';  M= -41,  -5,-123, -68, -27, -99, -22,  75,   9,  -4,   0, -22, -15, -38, -57, -25, -33,  39,-125, -54;
/M: SY='P';  M= -47,-131,  26,  28,-131, -35,-112,-123,   1, -90,-118, -75, 103, -65, -13,   5, -26, -67,-129,-124;
/M: SY='Y';  M= -36, -82, -51,  26, -23,  60,  19, -89, -81, -48, -32, -60, -40,  -4, -57,   8,  -4, -18,  -2,  61;
/M: SY='I';  M= -33, -56, -60,-124, -20, -86, -52,  76, -78,  32,  44,-122, -88,-119, -56, -58, -50,  42,-123,-104;
/M: SY='K';  M= -44,-121, -34, -44, -76, -38,  -6,  -3,  47,  30, -15, -63,-120,  14,  38, -24,   2,  27,-125,-108;
/M: SY='S';  M=  10,-119,   5,  23, -32, -22,  16,-117,  -7, -28, -34,  14,-115,  27, -22,  62, -16, -58,   0, -11;
/M: SY='F';  M= -16, -30,-129, -47,  65,-128, -59,  41, -79,  21,  19,-123,-127, -56,-121, -45,-109,  32,  61,  33;
/M: SY='H';  M= -13,-122,  -4,  46, -42, -65,  52, -19, -17, -93, -64, -11, -50,  34,  14,  33,  24, -27,   7, -19;
/M: SY='W';  M=  28,  14, -88,-119,  22,  -9,  27,  14,-118, -10, -29,-117, -74, -44,-120, -32, -33,  53,  75,   4;
/M: SY='G';  M= -20, -35, -29, -34, -49,  96, -38, -75, -34, -84, -21, -43,-116,-111, -68, -12,-112, -95,-123,-121;
/M: SY='P';  M=  -9, -48,-110,   3, -84, -51, -12,   3,  25, -31, -34,-107,  52,  -4,  46,   1,  25,  -3, -18, -39;
/M: SY='N';  M= -11, -30,  63, -62, -81, -63, -15, -28, -59, -91, -58,  85,  30, -14, -41,  -4, -18,  -8,-137,-117;
/M: SY='F';  M=   4, -30, -23, -24,  40, -89,   9,  16, -46,  15,  12,  30,-121, -30, -14,  -6,   2,  29,-120, -45;
/I:         I=-24; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='S';  M= -35,-119,  34, -22, -86,  27, -29, -96, -31, -46,-116,  13,  18,-101, -24,  74,  11, -69,-130, -75;
/M: SY='P';  M= -33, -73,  42, -19,  -2, -23,  16,  -7, -45,   7,-106, -70,  66, -34, -24,  -1,  27, -20,  -7, -69;
/M: SY='E';  M=  22,-123,  17,  68,-127, -50, -13,-124, -28,-123, -62,   8,  20,  16,  28,  20, -46, -58, -48,-117;
/I:         I=-6; MD=-15;
/M: SY='G';  M= -37,-146, -15,-128,-145,  32, -33, -18, -30, -86, -30,  22,  29,  -2, -17, -89, -39, -81,-149,-139; D=-6;
/I:         I=-6; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='R';  M= -44, -39, -38, -86, -50,-144, -27, -34,  -7,  12,   1, -39, -75,-124,  48, -45,-130, -21,  -4,-128; D=-6;
/I:         I=-6; DM=-15;
/M: SY='S';  M=  22, -30,  28,   9,-135, -33,   4, -86, -81,-130, -67,   2,-126,  20, -51,  38, -13, -15,-143,-126; D=-6;
/I:         I=-6; DM=-15;
/M: SY='Q';  M= -36, -52, -22,   3, -61,  19,   3, -63,  45, -82, -30,   4, -14,  48,  21, -25, -58, -47,-132,-120; D=-6;
/I:         I=-6; DM=-15;
/M: SY='G';  M= -13,-124,  13, -12,-129,  69, -28, -88, -28,-130,-122,  23, -20,-107, -24,  31,   3,-124,-130, -63; D=-6;
/I:         I=-6; DM=-15;
/M: SY='Y';  M= -28,   4, -67,-122,  72, -63,   3, -30, -79, -57,  15, -56, -50, -66, -87, -44, -86, -43,  80,  99;
/M: SY='D';  M= -70,-120,  79,  -5, -68,-114,  -5,-118,-103, -52,-115, -13, -38,  22, -49,  17,  73, -53,-138,-114;
/M: SY='H';  M= -87,-123, -24, -72,  47, -90,  99,  14,-115,   2,  20,-110,-124, -33, -69,-114, -50,  29,   3,  49;
/M: SY='A';  M=  56,  22,-120,-118, -34,  46,-120,  -4,-116, -64,  35,-110,-119,-114,-120,  -3, -62,  42,-126,-114;
/M: SY='F';  M=  -4,-119,-130, -88,  72,-126, -21,   8,-122,  51, -19, -76,-128,-121,-122, -26, -75,  15,  62, -13;
/M: SY='V';  M= -57,-120, -52,  -1,  -7,-125,   5,  35, -21, -13,   5, -54,-121, -44, -16,  -2,   5,  59,  -9,  35;
/M: SY='M';  M=  31,  17,-117, -63, -36, -32,-116,  12,-113,  -9,  46,-109,-118, -10,-116,  45,  29,  31, -29, -58;
/M: SY='T';  M= -48, -42,  40,  45, -23,-121, -46, -23, -21, -34, -55, -50,-115,  -2,  34, -49,  53,  14,-127,  -6;
/M: SY='F';  M=-121, -27,-133,-129, 117,-131,  24, -51,-125,  -7, -96,-123,-133,-131,-123,-121,-114,  -3, -95,  -1;
/M: SY='E';  M=  37,-122,  46,  55, -74,-113, -14,-120,  12, -85, -59, -10,  16,  -1,  -4, -20,  -8, -28,-130, -65;
/M: SY='D';  M= -50, -48,  71, -97, -83, -13, -50, -90, -71,-126,-120,  58,-115, -60,-110,  71,  20,-119,-137, -57;
/M: SY='K';  M=  14, -64, -45,  27, -45, -91,-112, -22,  36,  25,  17, -54,  19, -20,   8, -36,   6,   0, -16, -65;
/M: SY='E';  M=  41,-123,  51,  76,-128, -32, -58, -76, -30,-122,-117, -47, -54,  29, -69, -32, -29, -67,-129, -66;
/M: SY='D';  M=  54,-121,  86,  14, -78,  12, -14,-123, -69,-123,-119, -42,-115, -71, -70, -45, -40, -48,-133, -43;
/M: SY='L';  M= -63, -43,-124, -53,   7,-129,  20, -11,-107,  62,  43,-120,-127, -23,  47,-118,-111,  -5,  -8,  25;
/M: SY='D';  M=  18,-125,  74,  35, -76, -83, -49, -73,  19, -49,-115,  11,-115,  39,  19, -42, -53, -71, -27, -56;
/M: SY='Y';  M=  42,-119, -23,  16, -29,  -9, -14, -19, -22, -33, -58, -48,-117, -20,  12, -16,  27,  -9,-115,  55;
/M: SY='Y';  M= -84, -52,-121, -79,  30,-127, -90,-103, -74, -63, -50,-121, -45, -61,-112,-115,-114, -33, -27, 132;
/M: SY='Q';  M=  26,-122,  30, -27, -31, -60, -50, -16, -15,  16,  -6,  -9,-120,  62, -14, -27, -27,  -1, -10,   8;
/I:         I=-21; MI=0; MD=-53; IM=0; DM=-53;
/M: SY='T';  M=   7,-120,  17,  31, -79, -58, -34, -21,  17, -70, -25,  22, -11,  11, -37,  10,  32,  20,-130, -60;
/M: SY='H';  M= -66, -56,  51,  -7,-121, -63, 126,-132,-104,-123,-111,  30,-117, -98, -72,  23, -66,-129,-144, -40;
/I:         I=-20; MI=0; MD=-50; IM=0; DM=-50;
/M: SY='P';  M=  -2, -53,  -7,   5,-132, -84, -24,-122, -24,-129, -50,-115, 118, -71, -72, -66,-107, -77,-129,-127;
/M: SY='A';  M=  55, -59,  30,  35, -17, -58, -20, -31, -45,  -7,-106, -49,-117, -15, -28, -33,  -8,   0,-122,  15;
/M: SY='H';  M=-117,-129,-104,-104,-109,-121, 147,-126, -73, -50,-101, -95,-120, -22, -36, -78, -76, -54,-135,  36;
/M: SY='Q';  M=  -3,-123, -10, -11,-110, -52,   3, -28,  22,  22,  22, -47,-120,  62,  -4, -82, -37,  27,  43, -35;
/M: SY='A';  M=  52,-122,  20,  48,-126, -37, -47, -73,  34, -72,-114, -20, -44,  19,  16, -24, -49, -67,  -5,-116;
/M: SY='F';  M=   4,   1, -72, -92,  73, -67, -11,  21, -94,  14,   2, -78, -87, -69, -75, -61, -18,  43,  -2, -24;
/M: SY='V';  M=  24,-120, -38, -70,-112,   6, -26,  32,  38, -31, -38, -76,-119,   7, -19, -17, -31,  43,  11, -61;
/I:         I=-24; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='K';  M=  26,-122,  26,  40, -78, -25, -51,-123,  44,-122, -36,  -8, -47,   9,  29,   7,   2, -68,-128,-116;
/M: SY='W';  M= -19, -67, -33,  11,  39, -38,  31, -24,  18,  18,-101, -24,-122,   2,  14, -38, -18, -25,  47,  31;
/I:         I=-17; MD=-42;
/M: SY='F';  M=  -1,   8,-129,-125,  48, -54, -57,  43,-122,  17,  -8, -29,-128, -48, -60, -46, -48,  47, -17, -17; D=-17;
/I:         I=-17; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='K';  M= -11, -29,  10,  29, -52,   2, -47, -50,  42,   5,   5, -55, -52,   2,  24,  -2, -25, -36,  33, -76;
/M: SY='P';  M=  -8, -59, -18, -16,-125, -10,  20, -69, -20, -44, -46, -19,  93, -11, -26,  21, -23, -24, -43, -70;
/M: SY='V';  M= -10, -68, -64,   3,  14,   0, -65,  21, -42,  24,  10,  -4,-123, -36, -31, -72, -27,  38, -35,  28;
/M: SY='W';  M=  24,  24, -89, -34,  -8, -67, -61,  16, -16,   3, -10, -56, -31, -65,  15, -31,  -5,  37,  69, -19;
/M: SY='E';  M=  21,-123,  42,  72,-127, -29, -63, -37, -30, -94,-117, -27, -32,  -1, -17,  23, -11, -62,-131, -71;
/M: SY='D';  M= -35, -71,  46,  16,-127,  17, -74, -61,  42, -49,-116, -20,  -4,  26,  15,  23,  -5, -76,-129, -84;
/M: SY='R';  M= -15,-122, -43, -36,   0, -83,-116,  25, -69,  -8, -11,-114, -28, -46,  52,  -6,   2,  48,  25, -18;
/M: SY='I';  M=   1, -39, -87, -37, -17, -83, -62,  39, -12,  29,  13,-117,-123,  17, -16, -41,   7,  37,-125, -59;
/M: SY='V';  M=  26,  28,-123, -36, -74,-122, -26,   6,-114, -85,  -1,-117, -70, -73,  -2,  -2,  10,  72,-132, -41;
/M: SY='V';  M=   5,  -8,-129, -80,  46,-129, -49,  37,-122,  -2,   9, -83, -73,-122, -76,-115, -28,  55, -32,  40;
/M: SY='D';  M= -69, -57, 110, -21, -44, -69, -21,-131,-105, -59,-125,  -4, -66,  17, -66,-106,-109,-129,-140,  -1;
/M: SY='Y';  M= -34,-124,-128, -92,  82, -55, -18,   0,-122,   1, -10,-122,-131,-121, -75, -19,-113, -17,   6,  84;
/I:         E1=0; IE=-255; DE=-255;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	10 in 8 different sequences
Number of true positive hits	10 in 8 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	2
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	Stress-response A/B barrel
Version [info]	5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

8 sequences

DABB1_ARATH (Q9SYD8), FUSA4_GIBZE (I1RVD6), OLIAC_CANSA (I6WU39),

POP3_ARATH  (Q9LUV2), STBP1_POPEU (P84986), UP3_ARATH   (Q9SIP1), 
Y4036_STRCO (P37977), Y5258_ARATH (Q9FK81)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

16 PDB

1Q4R; 1Q53; 1RJJ; 2Q3P; 5B08; 5B09; 5B0A; 5B0B; 5B0C; 5B0D; 5B0E; 5B0F;
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