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PROSITE entry PS51471


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51471
Entry name [info] FE2OG_OXY
Accession [info] PS51471
Entry type [info] MATRIX
Date [info] 01-DEC-2009 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51471
Associated ProRule [info] PRU00805

Name and characterization of the entry

Description [info] Fe(2+) 2-oxoglutarate dioxygenase domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=89;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=84;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-0.3262750; R2=0.0040166; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=14922.6474609; R2=1.8172249; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=2049; H_SCORE=18646; N_SCORE=7.9; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1700; H_SCORE=18012; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-36; D=-100; I=-100; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 554 in 554 different sequences
Number of true positive hits 554 in 554 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 13
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.71 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] PS_Langendijk_Genevaux
Feature key [info] DOMAIN
Feature description [info] Fe2OG dioxygenase
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
554 sequences

2ODD_SINHE  (A0A0N9HQ36), ACCH1_ARATH (Q84MB3), ACCH2_ARATH (Q9C5K7), 
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UniProtKB/Swiss-Prot
False negative sequences
13 sequences

ALKB4_HUMAN (Q9NXW9), ALKB4_MOUSE (Q9D8F1), ALKB7_BOVIN (Q2M2S8), 
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PDB
[Detailed view]
312 PDB

1BK0; 1BLZ; 1DCS; 1E5H; 1E5I; 1GP4; 1GP5; 1GP6; 1HB1; 1HB2; 1HB3; 1HB4;
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