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PROSITE entry PS51464


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51464
Entry name [info] SIS
Accession [info] PS51464
Entry type [info] MATRIX
Date [info] 01-SEP-2009 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51464
Associated ProRule [info] PRU00797

Name and characterization of the entry

Description [info] SIS domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=141;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=141;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.0406272; R2=0.0057840; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=1377; N_SCORE=10.0; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=633; N_SCORE=5.7; MODE=1; TEXT='R?';
/DEFAULT: M0=-31; D=-100; I=-100; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Post-processing [info]

COMPETES_HIT_WITH PS51463
PROMOTED_BY PS51071

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 968 in 783 different sequences
Number of true positive hits 968 in 783 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.79 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] PS_Langendijk_Genevaux
Feature key [info] DOMAIN
Feature description [info] SIS
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
783 sequences

AGAS_ECO57  (Q8XAC2), AGAS_ECOLI  (P42907), AGAS_ECOLX  (Q9KIP9), 
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UniProtKB/Swiss-Prot
False negative sequences
2 sequences

GALDH_ARATH (O81884), GLCAE_SACS2 (Q97WE5)

		
PDB
[Detailed view]
87 PDB

1JEO; 1JXA; 1M3S; 1MOQ; 1MOR; 1MOS; 1NRI; 1TK9; 1TZB; 1TZC; 1VIM; 1VIV;
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