PROSITE entry PS51462

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51462
Entry name [info]	NUDIX
Accession [info]	PS51462
Entry type [info]	MATRIX
Date [info]	01-AUG-2009 CREATED; 26-FEB-2020 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00695
Associated ProRule [info]	PRU00794

Name and characterization of the entry

Description [info]

Nudix hydrolase domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=132;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=127;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.4772368; R2=0.0053481; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=15837.5009766; R2=5.5553956; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1501; H_SCORE=24176; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1127; H_SCORE=22098; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-16; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;

...

                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='P';  M= -9,-30,-12, -9,-35, 12, -4,-35,  9,  2, 35,-13, 51,-28,-12,  3,  1,-25, 29, -7;
/M: SY='W';  M=-34,-64,-26,-46,-26,-43, 12,-25, 22, 15,-29,  2, -4,-15, 48, -5,-10,-30, 58, 46;
/M: SY='H';  M=-39,-65,-20,-24,-11, -8, 84,-13,  4,-47,-21, -2,-17, -1, 57,-32, -3,-10,-65,  0;
/M: SY='R';  M= 11,-28, 14, -3,-26,-48, 13,-20,-12, 13,-27,-28, 34,  4, 45, -6,-27, -7,-66,-50;
/M: SY='A';  M= 50,  4,-22,-38,-59, 17,-10,-47,-41,-39,-49, 22, 22,-37,-55, 16,  8, 17,-68,-43;
/M: SY='V';  M= 17, 21,-46,-19, 44,-48,-60, 10,-55,-36, -7,-30,-62,-56,-37,  3,  4, 58,-60,-20;
/M: SY='G';  M= 17,-19,-27,-53,-26, 47, 10,-19,-51, -7,-21,  7,-41,-35,-42, 38,-10,  5,-24,-22;
/M: SY='I';  M= 20, 56,-64,-48,-33, -9,-64, 56,-59,-10, -5,-39,-62,-44,-63,-23,-13, 42,-66,-25;
/M: SY='I';  M=  0, 30,-38,-61, 25,-28,-23, 35,-38, 24, 28,-60, -3,-58,-60,-53,-32, 29, 25, 18;
/M: SY='I';  M= -5,-35,-68,-62,-22,-49,-63, 52,-61, 45, -4,-63,  6,-44,-50,-38,-36, 41,-63,-46;
/M: SY='F';  M= -4,-11,-39,-24, 52,-55,-10, 31,-54, 21,  5,-57,-64,-30, -4,-37, -9, 19,-23, 29;
/M: SY='N';  M=-12,-17, 35, -9,-45,-51, 18,-15,-13,-34,-49, 63,-57, -9, 29, -2, 16,  5,-74,-52;
/I:         I=-10; MD=-26;
/M: SY='P';  M=-46,-78,  6, 24,-60,-22,-38,-74, 10,-65,-42,-23, 29,  1, 17,-37, 11,-51,-78,-24; D=-10;
/I:         I=-10; MI=0; MD=-26; IM=0; DM=-26;
/M: SY='S';  M=-27,-18, 18, -2,-75, 13, -4,-54, -9,-33,-23,  3,-18,-19,-35, 19,-19,-43,-83,-68; D=-10;
/I:         I=-10; DM=-26;
/M: SY='D';  M= -8,-63, 50, 22,-35,  5, 14,-37, 25,-32,  7,  3, -3,  6, 10,-26, -7,-22,-68,-36;
/M: SY='G';  M=-28,-20, 25,-21,-27, 43,-47,-18, 21, -9,-31, 31,  2,  8, -2,-22,-15,-37,-63,-10;
/M: SY='E';  M=-18,-26,-23, 45,-40,-58, 39,-63, 44,-33,-50,-25,-53, 44, 45,-19,-24,-60,-62,  0;
/M: SY='V';  M=-27,  3,-69,-43, 20,-71,-65, 46,-63, 30,-18,-65,-30,-62,-64,-57,-34, 62,-61,-22;
/M: SY='L';  M=-54,-17,-72,-65, 30,-72,-59, 12,-64, 68,-12,-69,-70,-60,-63,-52,-50, 17, 55, -2;
/M: SY='L';  M=-18,-15,-71,-64, -9,-70,-59, 23,-63, 63, 45,-66,-67,-58,-62,-59,-33, 31, 18,-28;
/M: SY='Q';  M=  7, 32,-56,-51,-51, 12,-20, 17,-51,  7, -7,-28, -7, 46,-54,-35, 28, 30,-67,-51;
/M: SY='Q';  M=-24,-23,-44,  1,-47,-57,  5,-61, 43,-43, -2,-22,-56, 72, 62, -5,-39,-43,-63,-49;
/M: SY='R';  M=-25,-67,-27, -2,-63,-36, -9,-53, -7,-41,-12,-32,-59, 38, 93,  1,-49,-51,-64,-50;
/M: SY='S';  M= 30,-57,-51,-46, 10,-33,-21,-11,  9,-25,-46, -6,  1,  1, 13, 43,  8,-28,-19, 17;
/I:         I=-3; MD=-8;
/M: SY='D';  M=  7,-66, 39,  0,-23,-57,-15,-43, 15,-13,-53, 18, -9,-13, 38, -6,-11,-47,-70,-29; D=-3;
/I:         I=-3; MD=-8;
/M: SY='S';  M=-48, -5, -1,-16,-41,-23,  4,-30, -7,-60,-25,  2,-15,  9,  5, 20, 20,-31, -7,-19; D=-3;
/I:         I=-3; MD=-8;
/M: SY='K';  M=-33,-88,-58,-53,  4,-83,-75,-74, 44,-21,-69,-71, 21,-29,-29,-52,-71,-41,-82,-70; D=-3;
/I:         I=-3; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='P';  M=-47,-45,-63,-31,-79,-53,-65,-64, -2,-64,-69,-61, 85,-28,-53, 32,-42,-73,-78,-36; D=-3;
/I:         I=-3; DM=-8;
/M: SY='G';  M=-23,-64, 11, -8,-66, 75, 39,-70,-51,-30,-41, 38,-28,-48,-46,-33,-51,-67,-69,-58; D=-3;
/I:         I=-3; MI=0; MD=-8; IM=0; DM=-8;
/M: SY='M';  M= -4, 27,-10, 13, -2,-23, 17,-20,-12, 17, 35,-33,-60, -4,  4,-13,-16,  8,-18, 29;
/M: SY='W';  M=-58,-72,-78,-66, 25,-56, -5, -7,-61, 22,  0,-72,-68,-59,-62,-64,-61, -5,147, 24;
/M: SY='Q';  M=  4, -6, 28, 19,-32, -1,-49, -1, -6,-41,-33,-25,-54, 41,-46, 20, 24, 11,-67,-29;
/M: SY='F';  M=-26,  8,-45,-59, 64,-44,-26,  8,-57, 30, 28, 40,-21,-30,-58,-28,-46, 12,-53,-32;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='P';  M=-37,-68,-55,-47,-39,-56,-57,-25,-51, -9,-48,-41,104,-53,-61, 10, 10,  0,-66,-40;
/M: SY='G';  M= 34, 60,-52,-49,-66, 61,-54,-64, 14,-62,-18,-42,-56, 29,-29,-22, -2,-56,-65,-60;
/I:         I=-15; MI=0; MD=-39; IM=0; DM=-39;
/M: SY='G';  M=-36,-63,-51,-62,-69, 96,-58,-73,-56,-71,-61,-38,-55,-53,-63,  4,-42,-42,-62,-64;
/M: SY='H';  M=-36,-62,-51,-36, 29, 31, 83,-51, 31,-19, 29,-31,-58,-43,  7,-23,-16, -9,-61,-26;
/M: SY='P';  M=-24,  9,-67,-59,-43,-67,-63, 43,-45, 17, 19,-62, 49,-57,-11,-46,-37, 48, 40,-48;
/M: SY='E';  M=-24,-65, 58, 66,-65,-32,-18,-52,  8,-18,-55, 12,-34,  9,  1,-23,-46,-42,-71,-43;
/I:         I=-6; MI=0; MD=-14; IM=0; DM=-14;
/M: SY='P';  M=  6,-17,  4, 18,-25,-38, -2,-20, 18,-19,-34,-17, 69, -7,-17,  5,-36,-24, -4,-23;
/M: SY='G';  M=-37,-37, 52, -9,-69, 75,-50,-71,-11,-58,-41,  9,-25,-24,-45, -9,-49,-56,-68,-61;
/M: SY='E';  M=-40,-68, 16, 98,-67,-40,-42,-43, -8,-40,-57,-43,-45, -9,-31,-44,-48,-50,-67,-35;
/M: SY='S';  M=-30,-34, 20, 12,-62,-26,-27,-57, -5,-60,-28, 11, -5, -2,-38, 58, 57,-32,-72,-55;
/M: SY='P';  M=  1,  4,  9,-20,-12,-61,-35, 34,-54, 17,-15,-18, 51,-13,-59,-35,-32, 22,-28,  3;
/M: SY='E';  M= -1,-63, -8, 55,-12,-34,-30,  0,-16,  8,-10,-48,-10, 20, -3,-14,-12,-10, 10, 10;
/I:         I=-14; MI=0; MD=-35; IM=0; DM=-35;
/M: SY='E';  M=  0,-64, 48, 57,-62,-20,-11,-15,-16,-43,-29,-19,-51, 39,-14,-11,  5,-22,-68,-19;
/M: SY='C';  M= 65, 74,-54,-52,-61, 14,-57,-55,-39,-56,-51,-21,-56,-50,-57,  0, 34,-27,-69,-60;
/M: SY='A';  M= 66,-13,-62,-55,-18,-25,-59,  2,-56, 24, 14,-56,-60,-53,-59,-40,-33, 25,-63,-50;
/M: SY='R';  M= -6,-15,-56, -8,-36,-63, -3, 26, -4, 26,  9,-22,-61, 10, 31,-12,-29, 23,-62, -6;
/M: SY='R';  M=-54,-36,-50,-30,-64,-64,-40,-70,  8,-62,-51,-43,-62, -4,109,-48,-44,-63,-63,-50;
/M: SY='E';  M=-48,-68,-23, 99,-68,-64,-41,-52, -8,-39,-57,-45,-46,-23, 27,-45,-49,-62,-67,-59;
/M: SY='L';  M= 10,  3,-65,-60,  9,-44,-59, 21,-59, 48,  1,-58,-63,-57,-61,-25, 27, 29,-61,-30;
/M: SY='W';  M=-23,-26,-23, 36, 11,-30,  3,-31, 30,-22,  6,-15,-56, 19, 28,-24,-20,-18, 65, 14;
/M: SY='E';  M=-31,-68, -3,102,-56,-62,-12,-54,-22,-63,-59,-43,-44, -2,-26,-44,-48,-63,-67,-45;
/M: SY='E';  M=-48,-69,-19,106,-70,-64,-41,-54,-22,-63,-60,-45,-43,-22,-39,-45,-48,-63, -7,-60;
/M: SY='T';  M= 23,-26,-57,-55,-35,-48,-28, 17,-54, 33,  0,-50,-57,-52,-58,  6, 58, 16,-66,-48;
/M: SY='G';  M=-35,-63,-13,-58,-68, 90,-34,-73,-52,-59,-37, 27,-56,-51,-23,-21,-29,-68,-11,-62;
/M: SY='I';  M=-33,-21,-64,-20,  9,-56,-34, 60,-59, 32,-18,-42, -7,-57,-34,-45,-23, 28,-55, 24;
/M: SY='D';  M=-13,-62, 44,  6,-32,-39, -2,-15, 18,-13,-48, -6, 18,  0, 19,  9, 19,-12,-68,-36;
/I:         I=-13; MD=-34;
/M: SY='V';  M= 10, 13,-46,-25,-23, 14,-21,  6,-20, 21,-24,-19, 24,-53,-34,-10,-18, 24,-66,-37; D=-13;
/I:         I=-13; MD=-34;
/M: SY='E';  M= -6,-65, 25, 29,-64,-18,-17,-30, 20,-21,-54, -3,  3, 12,-14,  9, 10,-21,-72,-41; D=-13;
/I:         I=-13; MD=-34;
/M: SY='D';  M=-17,-68, 20,-12, -4,-64,  1, -3, 10,  0,-17, -4, 17,  8,-28, -6,-11, -6,-70,-27; D=-13;
/I:         I=-13; MI=0; MD=-34; IM=0; DM=-34;
/M: SY='V';  M=-25,-59, -9,  8, 14,-28,-36, 21,-44, 19, -8,-17,-23,-51,-28, -2,  3, 41,  0,  5;
/M: SY='E';  M=-12,-39, 31, 34,-60,-44, -8, -9,  6,-30,-49,-18,-23, 26, 28, 21,  5,  2,-68,-35;
/M: SY='Y';  M=-42,-60, -3,-21, -8,-59, -8, 20,  2, 17,-14, 22,  9,-10,-50,  9,-20, 26,-57, 37;
/M: SY='L';  M=-33,-63,-31, -6,-21,-35, 27, 24,-50, 45,-32,-34, 36,-50, 13,-54,-21,  3, 30,-14;
/I:         I=-5; MD=-13;
/M: SY='G';  M= 19,-22,-10,-30, -2, 42,-56,-66, 14,-38,-58,-14,-32, 13, -8,  1,-22,-54,-67,-42; D=-5;
/I:         I=-5; MD=-13;
/M: SY='F';  M=-45,-22,-53,  5, 45,-74, 10,-39, -4,-21,  3,-63,-54,-47,-38, 24,-46,-46,-70,-50; D=-5;
/I:         I=-5; MD=-13;
/M: SY='Q';  M=-44, 24,-60,-72,  1,-86,-76, -9,-55,-21,-32,-72,-84, 27, -9,-48, 21,-40,-85,-42; D=-5;
/I:         I=-5; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='Y';  M=-50,-74, -2, 11,-45,-37,-21,  2,-57,-44,-54,  1, 10,-11,-35,-10,-14, 19,-66, 43; D=-5;
/I:         I=-5; DM=-13;
/M: SY='W';  M=-48,-67,-63,-30, 39,-42,-53,-45,  6,  4,-17,-58,-64,-49, 33,-29, -2,-10,115, 45;
/M: SY='P';  M=  5,-36,-23, 27,-25,-27, 31, 15,  0, -4,-27,-28, 33, 18,-12,  5, -7,-10,-64,-18;
/M: SY='H';  M= -2,-38,  1,-31, 50,-40, 50,  8,-27,-44,-10,-38, 18,  4,-13,  5,  8,-14,-51, 35;
/M: SY='Y';  M=-31,-64, -8,-13, 35,-29,  3,-35,-13, 10,  4,  8, 48,-35,-35,-20,-34,-19,  9, 63;
/I:         I=-9; MD=-22;
/M: SY='D';  M= -9,-38, 55,-37,-25,-63,-51,-65, -1,-64, 13,-20,-66, 15, 10,-12,  6,-42,-70, 24; D=-9;
/I:         I=-9; MD=-22;
/M: SY='D';  M=-13,-83, 23,-24, -7,-23,-11,-48,-23,-37,-71,-17, 11,-64,-41,  2,-64,-74,-81, -3; D=-9;
/I:         I=-9; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='P';  M=-60,-18,-26,-60,-49, 16,-22,-66,-16,-72,-41,-72, 40,-39,-60,-47,-47,-48, -1,  6; D=-9;
/I:         I=-9; DM=-22;
/M: SY='R';  M=-66, -7,-71,-58,-13, 15,-49, -1,-11,-10,-38, -6,-35,-63, 29,-32,-35,-63, 22,-64; D=-9;
/I:         I=-9; DM=-22;
/M: SY='G';  M=-37,-72,-38,-35,-12, 39,-26,  4,-43,-14,-54,  6,-53,-23, -8,-30, -7,  0,-74,-40; D=-9;
/I:         I=-9; DM=-22;
/M: SY='Q';  M=-40,-68, -2, 33,-20,-30, -2,-35, 21,-28,-54, -6, -9, 39,-35, -9, 25,-17,-26,-40; D=-9;
/I:         I=-9; DM=-22;
/M: SY='H';  M=-19, -9, 18,-11,-29, -7, 50,-23, 18,-23,-18, 20, -2, -5, 19,  7,  1,-14, 23,-14;
/M: SY='E';  M=-20, 12,  5, 45,-24,-56, 30,-10,-17,-25,  9,  6,-42, 34,-11, 20,  2,-42, -1, 22;
/M: SY='V';  M= -8,-60,-45,-17, 22,-44,  4, 20, 17, 12,  3,-30,-61,-10,  5,-15, -6, 27, 12, 16;
/M: SY='W';  M=-29, 53, 13,-16, 16,-24, -7, -8,-20,-14, 37,-17,-45,  4,-22,-28, -2, 11, 92, -8;
/M: SY='H';  M=-26, -5,-26,-54, 50,-39, 59,  3,-20, -8, 22, -8,  1,-36,-21,-32,  6, -7,-48, 52;
/M: SY='W';  M= -1,  0,-62, -8, 13,-22,-35, 27,-57, 22, -9,-60, -8,-55,-60,-45,-12, 36, 49, 38;
/M: SY='Y';  M=-14, 21,-66,-50, 60,-66,-10,  5,-59, 24, 24,-61,-67,-58,-59,-54,-12, 11, 23, 64;
/M: SY='V';  M= -6,  4,-19, -7, 18,-35,-21, 17,  6, 22,-23,-53,-62,  1, 17,-27,-24, 34,-61,-28;
/M: SY='A';  M= 36, 24,-31,-46, 22, 18,-40,  5,-26, 15,-16,-31,  8,-19,-57,-37,-46,  8,-57,  5;
/M: SY='R';  M=-26, 22,  5, 27, 16,-43,-17,-18, -4, -4,-44,  9,-28, -3, 34,-13,  3, 17,-63,-16;
/M: SY='V';  M=-15, 20,-35,-19,-12,  9,-20, 11,-25, 22, -6, 18,-27,-51,-23,  0, -1, 27, -7, -4;
/M: SY='D';  M=-36,-38, 44, 17,-24,-47,  9,-36,  9, -3,-28,  4, 30, -6,  0,  8, 20,-19, -4,-21;
/M: SY='H';  M=-10,-19, 35, 12,-58, 12, 37,-44,  3,-16,-20,-31, 27,  2,-31, 19,  8,-17,-67, -7;
/M: SY='D';  M= -4,-22, 43, 31, -7,  2, -8,-31,-13, -7,-34, -1, 12, -5,-25,  5, 17,-24,-68,-52;
/M: SY='Q';  M=-17,-63, 18, 31, -5,-24,-10, -9, -5, 10,-21,-13, 26, 37,-16, 10,  0,-33,-64,-49;
/M: SY='I';  M=-20,-19,  5, -6, 11,-24,-35, 42,-14, -5,-22, 13, 14, 24,-11,-21, -7,  7,-26,-19;
/I:         I=-5; MD=-13;
/M: SY='P';  M=-21,-40,  2, 16, -4,-12,-29, -4, -8, -8,-19, 14, 39, 29, 17, -8,-26,-18,-27,-13; D=-5;
/I:         I=-5; MD=-13;
/M: SY='N';  M=-18,-24,  1,  5,-53,-23,-18, 16, -5,  0,-14, 32, 16, 14,-17,-23,-10,  0, -4, -5; D=-5;
/I:         I=-5; MD=-13;
/M: SY='P';  M=-35,-20, 24, -4,-35,-46,-12,  3,-20, -7,-50, 21, 46, 24, -5,-17, -5,-24,-27,-41; D=-5;
/I:         I=-5; MD=-13;
/M: SY='N';  M=-18,-74,-22,-15,-18,-40,-19,-61,  1,-17,-22, 28, 22, -1,-19,-26, -9,-19,-75, -5; D=-5;
/I:         I=-5; MD=-13;
/M: SY='P';  M=-28,-26, 15,-11,-82,-27, -3,-54,-32,-36,-34, 11, 19,-24,-38,-20, -4,-62,-93,-76; D=-5;
/I:         I=-5; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='D';  M= -5,-10, 43, 13,-27,  7,  9,-59,  2,-29,-53, 16, 38,-10, -3, 12,-10,-29,-68,-26;
/M: SY='E';  M=-47,-68, 21,102,-71,-62,-41,-71,-30,-64,-60,-42,-44,-13,-40,-36,-11,-63,-69,-60;
/M: SY='V';  M=-10, -3,-46,-58, 41,-40, 26, 33,-43,-10,-12,-23,-47,-32,-47,  9,  1, 49,-60,-27;
/I:         I=-22; MI=0; MD=-57; IM=0; DM=-57;
/M: SY='D';  M=  1,-40, 21, 19,-42,-18,-21,  2, 19, -7, 13,-20,-32, 12, 15, 20,-10,-14,-64,-13;
/M: SY='E';  M= 19,-39, 39, 43,-67, 13, -6,-65, 17,-57,-57,  7,-13,  8,-10, 19,-18,-59,-69,-57;
/M: SY='W';  M= 17,  9,-67,-61, 21,-17,-58, 25,-56, 14,-36,-47,-50,-42,-11,-41,-42, 26, 89, 32;
/M: SY='R';  M= -8, 11,-25, 25, 23,-32,  4,-20, 37,-31, -8,-17,-57, 21, 42,-15,-47,-10,  1,-29;
/M: SY='W';  M=-59,-76,-45,-25, 25,-62,-38,-25,-33,-10,-32,-49,-49,-55,-19,-37,-48,-33,155, 16;
/M: SY='V';  M=-33,-12,-55,-61, 34,-52,  6, 28,-58, 22, 34,-47,-65,-14,-33,-29,-34, 50, 40, -2;
/M: SY='P';  M=-25,-62, 38, 19,-50,-22,  4,-61, -2,-64,-56, 12, 54,-18,-21, 40, 28,-46,-71,-36;
/M: SY='P';  M=-15,-63,-60,-14, -7,-64,-33, 14,-29, 39,-21,-59, 46, -2, 12,-38,-31,  2, 39, 24;
/M: SY='E';  M=  5,-63, 41, 51,-63,-46, 13,-62, 19,-46,-22, 20, -6, 23,-22,  3, -6,-51, 17,-26;
/M: SY='E';  M=-14,-33, 48, 62,-49,-48,  4,-52,  2,-48,-39,-12,-51, 33,  2,  8,-26,-31, -8,-18;
/M: SY='L';  M= 27,-35,-64,-58, 11,-50,-56, 13,-26, 50,  7,-35, -9,-36,-41,-42,-29, 19,-57,  1;
/M: SY='P';  M= -5,-16,-36,-17,-13,-27,-21, 13,  3, 27, -5, -1, 37, -2,  5,-34, -9, -1, 21, -7;
/I:         I=-17; MD=-42;
/M: SY='E';  M= 20,-20, 30, 39,-30,-46, -2,-50, 13,-22,-31, 19, -5, 23,  0, -9,  1,-55,-68,-39; D=-17;
/I:         I=-17; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='L';  M=  3,-62, 18,  4,  3,-24, -7,-17,-13, 27, 21, -4, 14, 15, 13,-17,-47,-28,  4,-30;
/M: SY='C';  M=  5, 49, -5,-15,  1,-61,-54,  5,-38, 24,  8,-20, 12,-38,-38,-31, 12, 18,-60, 21;
/M: SY='H';  M= 19,-62, 22, -9,-57,-46, 28, -7,  9,-28, -4,  0, 14, 24, 10,  1, -7,  6, 18,-37;
/M: SY='S';  M= 14,-60, 16,  5, -5,-27, 10,-32, 18,-40, -8, 30, 16,-30,-11, 31, -7,-36,-62, 11;
/M: SY='F';  M= -4,-62,-48, 11, 38, 15, 34,-37,-10,-31,-33, 12,  6,-17,  1, -8, 13,-46,  1, 36;
/M: SY='K';  M=-24,-64, 29, 24,-59,-29,-28,  0, 47,-35,-51,  0, 27,-18, -3,  8, -8,-25, 32,-26;
/M: SY='W';  M= -7,-29, -4,-13, 14, -5, -8, 16,  2, -4, 18, -6, -1, -2, 19,-27,-26,-10, 47, 20;
/M: SY='K';  M= 19,-36,  6, -7, -8,-21, 10, -8, 22,  2,-44, -5, 10, 11, 10,-20,-14, -9, 21, -7;
/M: SY='Y';  M=-21,  2, -5, -2, 24,-52,-22, 20,  1, 11, 12,-19,  8,-24, -2, -9,-39, 17,-54, 30;
/M: SY='Y';  M= 28,-37,-19,-40, -7,-21,-46,-33,-21,  2,-18,-16,-17,  3,-15, 16, 26, -6,-50, 58;
/M: SY='P';  M=-21,-11, -8, 10, -3,-61,-34, 20, 12, 25, -7,-52, 47,  5,-14, -2,-36, -4,-23,-48;
/M: SY='W';  M= -7,-65,  7,  2, -6, -5,-50,-13,  4, -2,-46, -2,  6, 18, 17, -9,-24,-22, 87, 10;
/M: SY='F';  M=  5,-22,-21, -9, 34, -9,-52, -4, -4, 15, 29,  8,-33, 14,-36,-22,-21, 17, 25,-29;
/M: SY='Y';  M=  9,-38,-56,-10, 18,-34,  1, 18, 15, 23, 21,-27,-22,-13, 10,-35,-32, -2,-54, 27;
/M: SY='Q';  M=  2,-38, 10, 14,  7,-44,-18,-20, 10, 18, -3,  1, -3, 18, -7,-17,  1, -6,-58, 15;
/I:         E1=0; IE=-255; DE=-255;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	939 in 939 different sequences
Number of true positive hits	937 in 937 different sequences
Number of 'unknown' hits	2 in 2 different sequences
Number of false positive hits	0
Number of false negative sequences	4
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	99.57 %

Comments [info]

Taxonomic range [info]	Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	Nudix hydrolase
Version [info]	6

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	937 sequences 080R_IIV3 (Q196Y0), 8ODP_CANLF (F1P963), 8ODP_DANRE (Q7ZWC3), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	4 sequences CFIS1_ARATH (Q94AF0), CFIS2_ARATH (Q8GXS3), MUTYH_ARATH (F4JRF4), MYH1_SCHPO (Q10159) » more
UniProtKB/Swiss-Prot 'Unknown' sequences	2 sequences IDI_ECOBW (C5A0G1), IDI_KOCRD (B2GFH1)
PDB [Detailed view]	579 PDB 1G0S; 1G9Q; 1GA7; 1HX3; 1HZT; 1I9A; 1IRY; 1KHZ; 1KT9; 1KTG; 1MK1; 1MP2; » more