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PROSITE entry PS51462


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PURL: https://purl.expasy.org/prosite/signature/PS51462

Direct ScanProsite submission
General information about the entry

Entry name [info] NUDIX
Accession [info] PS51462
Entry type [info] MATRIX
Date [info] 01-AUG-2009 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00695
Associated ProRule [info] PRU00794

Name and characterization of the entry

Description [info] Nudix hydrolase domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=132;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=127;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.4772368; R2=0.0053481; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=15837.5009766; R2=5.5553956; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1501; H_SCORE=24176; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1127; H_SCORE=22098; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-16; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 939 in 939 different sequences
Number of true positive hits 937 in 937 different sequences
Number of 'unknown' hits 2 in 2 different sequences
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.57 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] Nudix hydrolase
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
937 sequences

080R_IIV3   (Q196Y0), 8ODP_CANLF  (F1P963), 8ODP_DANRE  (Q7ZWC3), 
» more

UniProtKB/Swiss-Prot
False negative sequences
4 sequences

CFIS1_ARATH (Q94AF0), CFIS2_ARATH (Q8GXS3), MUTYH_ARATH (F4JRF4), 
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UniProtKB/Swiss-Prot
'Unknown' sequences
2 sequences

IDI_ECOBW   (C5A0G1), IDI_KOCRD   (B2GFH1)

		
PDB
[Detailed view]
579 PDB

1G0S; 1G9Q; 1GA7; 1HX3; 1HZT; 1I9A; 1IRY; 1KHZ; 1KT9; 1KTG; 1MK1; 1MP2;
» more