PROSITE logo

PROSITE entry PS51444


View entry in original PROSITE format
View entry in raw text format (no links)
View entry auxiliary file in raw text format (no links)
Direct ScanProsite submission
General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51444
Entry name [info] FH2
Accession [info] PS51444
Entry type [info] MATRIX
Date [info] 01-MAR-2009 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51444
Associated ProRule [info] PRU00774

Name and characterization of the entry

Description [info] Formin homology-2 (FH2) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=399;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=394;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.1929207; R2=0.0175466; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=303; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=189; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-100; I=-100; B1=-1000; E1=-1000; MI=-105; MD=-105; IM=-105; DM=-105;
...
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 105 in 105 different sequences
Number of true positive hits 105 in 105 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] FH2
Version [info] 1

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
105 sequences

BNI1_CANAL  (Q5AL52), BNI1_YEAST  (P41832), BNR1_CANAL  (Q5AAF4), 
» more

PDB
[Detailed view]
20 PDB

1UX4; 1UX5; 1V9D; 1Y64; 2J1D; 2Z6E; 3O4X; 3OBV; 4EAH; 8RTT; 8RTY; 8RU2;
» more