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PROSITE entry PS51440


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51440
Entry name [info] TIM_2
Accession [info] PS51440
Entry type [info] MATRIX
Date [info] 01-MAR-2009 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00155
Associated ProRule [info] PRU10127

Name and characterization of the entry

Description [info] Triosephosphate isomerase (TIM) family profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=244;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=239;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.9888400; R2=0.0071089; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-15939.3437500; R2=25.5977039; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1057; H_SCORE=11117; N_SCORE=9.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=635; H_SCORE=315; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-21; D=-100; I=-100; B1=-350; E1=-350; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 661 in 661 different sequences
Number of true positive hits 661 in 661 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] PS_Langendijk_Genevaux
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
661 sequences

ERYH_BRUA2  (Q2YIQ6), ERYH_BRUAB  (P0C119), ERYH_BRUME  (Q8YCV3), 
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PDB
[Detailed view]
210 PDB

1AG1; 1AMK; 1AW1; 1AW2; 1B9B; 1BTM; 1CI1; 1DKW; 1HG3; 1HTI; 1I45; 1IF2;
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