PROSITE entry PS51434

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PURL: https://purl.expasy.org/prosite/signature/PS51434

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General information about the entry

Entry name [info]	NUP_C
Accession [info]	PS51434
Entry type [info]	MATRIX
Date [info]	01-FEB-2009 CREATED; 10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51434
Associated ProRule [info]	PRU00765

Name and characterization of the entry

Description [info]

NUP C-terminal domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=138;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=133;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.7975209; R2=0.0075680; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=24128.2714844; R2=2.6870775; PRIORITY=1; TEXT='Heuristic 0.1%';
/CUT_OFF: LEVEL=0; SCORE=754; H_SCORE=26154; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=490; H_SCORE=25445; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-41; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='K';  M= -22,  -4, -21,  -1, -29, -83,  30, -27,  60, -91, -82,  35,  30,   4,  36,  16, -27, -87, -96, -81;
/M: SY='P';  M= -75, -95,  46,  16,   0,  22, -75, -91, -21, -92, -86,   8,  51,  44, -77,  40, -72, -43, -93,   0;
/M: SY='G';  M=  -8, -95,  58,  55, -14,  58, -78,-100, -17, -96, -90, -67, -10, -69,  -3, -29, -78, -94, -96, -87;
/M: SY='Y';  M= -88,-100, -86, -86, -42, -94,  20, -77, -22, -74, -69, -86,   4, -76,   3, -83, -83, -82, -50, 131;
/M: SY='W';  M= -85, -99, -90,  14,  35, -93, -81, -25, -19, -34, -75, -91,   5, -25, -83, -32, -13,  -5, 128,  77;
/M: SY='C';  M= -76,  85, -88, -85, -20, -91, -85,   0,  11,  17,  75, -78, -89, -81, -82,   0,  60, -31, -98, -78;
/M: SY='S';  M= -22, -89, -19,  -9, -20, -84, -81, -10,  27, -12, -75, -13,  35,   2,  -5,  51,  -8,  27, -96, -81;
/M: SY='P';  M= -84,-109, -85, -74, -95, -86, -85, -90, -81, -99, -86, -91, 128, -84, -92, -81, -77, -95, -91,  17;
/M: SY='S';  M= -14,  -1,  23, -70, -93, -73,   4, -92,  -3, -94, -87,  12,   7, -67,  17,  86,  -1, -86,-101, -84;
/M: SY='I';  M= -83, -93, -97, -90,   7,-101, -87,  66, -10,  48,  30, -92,  31, -85,  -7, -89, -78, -15, -86,  -1;
/M: SY='E';  M=  -5, -93,  20,  74, -83, -87, -71, -22, -35,  -3,  -1,  22, -82,  38, -73, -21, -11, -81, -91,  29;
/M: SY='E';  M= -16,  11,  -3,  71, -95, -87, -76, -88,  28, -88, -82, -70, -79,  48, -12, -27,  49, -17, -98, -86;
/M: SY='L';  M= -83, -88, -16, -90, -64, -99, -86,  39, -91,  77,  16, -13,  -5, -86, -91, -88,   2, -56, -92, -74;
/M: SY='K';  M=   2, -91, -72,  30, -86, -26, -74,  -5,  35, -83,  -6,  31, -84,  28,  29,  17,   3, -10, -92,  13;
/I:         I=-20; MD=-50;
/M: SY='T';  M=  -5, -92,  -2,  41, -92, -13,  14, -93,  36, -92, -85,   6,  11, -18,  -5,  11,  44, -87, -97,  -1; D=-20;
/I:         I=-20; MD=-50;
/M: SY='M';  M= -41, -93, -96, -89,   9, -95, -77,   9,  -4,  20, 102, -89,  10, -80, -29, -22, -80, -67,  40,  56; D=-20;
/I:         I=-20; MD=-50;
/M: SY='T';  M=  16, -87, -15,   9, -90, -38, -84,  -5, -39, -48, -80, -22,  37, -76, -84,  41,  65, -16,-101, -87; D=-20;
/I:         I=-20; MI=0; MD=-50; IM=0; DM=-50;
/M: SY='P';  M=   1,  15,  26,  31, -27, -90, -81,  32,   3,   1, -73, -18,  44, -74,   8, -77,   0, -27, -94, -14;
/M: SY='E';  M= -24, -94,  37,  71, -95, -19, -73, -91,  18, -24,   5,  24,  -7,  35, -18, -71,  -5, -88, -98, -86;
/M: SY='Q';  M= -39, -98,  41,  52, -34,  -5,  26,   8,  -1, -86, -80, -69, -83,  83,  -2, -72, -79, -85, -93, -15;
/M: SY='L';  M= -32,  41, -92, -11, -67, -95, -82, -59, -83,  77,  27, -90, -96, -16,  10,   7, -77, -64, -92, -75;
/M: SY='R';  M= -36,  24, -77, -69, -93, -10,   1, -88,  50, -89, -81,  -8, -86,  43,  58,  46, -71,  -1, -96, -82;
/M: SY='N';  M=   7, -91, -71,  12, -29, -80, -73,  -8,  13, -87, -80,  55, -86,  51,  45,  32, -71, -40,  48, -79;
/M: SY='V';  M= -26, -85, -98, -32, -21,-100,-100,  26, -91,  -6, -59, -95, -95, -92, -93, -84, -70,  95,-100, -77;
/M: SY='P';  M= -76, -95,  28,  50, -92, -83,  51, -91,  -5, -90,  -2,  -4,  56,  28, -73,  36, -10, -43, -98,  -7;
/M: SY='N';  M= -77, -92,  62, -67, -97,  31,  65, -99, -70, -97, -87,  78, -87,  18, -11,   1, -21, -97,-108, -82;
/M: SY='F';  M= -91, -88,-105, -99, 115,-101, -85, -62, -96,  36, -62, -96,-103,-102, -93, -92, -84, -68, -63, -42;
/M: SY='T';  M= -73, -86, -79, -23, -82, -89, -85,  26,  31, -74, -72, -14, -84, -13,   5,   8,  73,  39,-100, -81;
/M: SY='V';  M= -41, -88,-102, -97, -69,-103,-103,  78, -94, -31, -57, -95, -94, -94, -96, -86, -72,  81, -98, -77;
/M: SY='G';  M= -67, -91, -81, -85, -13,  82, -83, -12, -81, -92, -85, -68, -86,  -1, -27,  54, -27, -87, -89,  -7;
/M: SY='R';  M= -84, -97, -74, -70,   0, -88,  35, -97,   4, -91, -81,  56, -92, -61, 103, -75, -79, -93, -95, -76;
/M: SY='E';  M= -78, -96,  16,  67, -94, -90,  20, -37,  47, -45, -81, -70, -13,  25,  29, -21,  -6, -19, -97, -83;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='G';  M= -37,-100,  17, -90,-107,  81,  -8,-112, -89,-110,-100,  42, -94, -87, -96, -23, -87,-107,-106,-100; D=-28;
/I:         I=-28; DM=-71;
/M: SY='Y';  M= -85,  21, -92, -90,  69, -95, -69,  -3,   8, -67, -68, -87, -98, -84, -80, -19, -79,  -1, -58, 106;
/M: SY='G';  M=  -9,  41, -83, -93, -99, 101, -89,-106, -87,-101, -91, -69, -87, -85, -94, -67, -84, -98, -93, -95;
/M: SY='Q';  M= -23, -92,  20,  37, -91, -81, -71, -94,  50, -92, -84,   2, -82,  53,   0,  49, -29, -89, -92,  14;
/M: SY='I';  M= -77, -90,-102, -99, -68,-106,-102,  90, -95, -11, -55, -95, -94, -94, -97, -88, -73,  67, -96, -76;
/M: SY='E';  M=  -9, -93, -24,  61,  -1, -88,   6, -84,  22, -43,  27, -73, -83,  11,  41,   4,  -5, -26, -90,  10;
/M: SY='W';  M= -93, -97,-107, -99, 106, -97, -88, -73, -93, -66, -74, -99,-101, -98, -92, -93, -90, -80, 128,  44;
/I:         I=-30; MD=-77;
/M: SY='P';  M= -85, -95,  47, -17, -80, -44, -82, -35, -36,  50,  30,  14,  59, -81, -88, -83, -15, -76,-100, -84; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='G';  M= -23, -92,  36,  41, -36,  44,  -2, -92,  29, -51, -85,  -4, -83,   0, -73,  17,  -2, -43, -95, -17;
/I:         I=-28; MI=0; MD=-71; IM=0; DM=-71;
/M: SY='P';  M= -80, -98,   3, -12, -90, -86, -81, -84, -11, -47, -83,   7, 104, -77, -30, -38,  35, -23, -95,  11;
/M: SY='V';  M= -72,  12, -93, -91, -19, -98, -98,  43, -88, -61, -63, -85, -91, -91, -92, -75,  59,  81,-101, -78;
/M: SY='D';  M= -82, -94, 106, -10,-102, -77, -68,-100, -70,-101, -96,  71, -85, -69, -78,  -7, -71, -98,-117, -88;
/M: SY='L';  M= -17, -87,-101, -94, -62,-101, -90,  30, -94,  78, -50, -98, -98, -89, -93, -90, -77,  35, -92, -73;
/M: SY='T';  M=   9, -85, -27, -76, -83, -80, -79, -76, -70, -14, -76, -70, -85, -12,  39,  60,  61,   7, -96,   0;
/M: SY='N';  M=  11, -92,  -2,  33, -83,  42, -72, -91, -68, -25, -82,  53, -87, -69,  39, -36, -27, -87, -88,  41;
/M: SY='I';  M= -22,   8, -98, -92,   0, -26, -93,  58, -91,  40,  -4, -91, -95,  -3, -92, -84, -22,  50, -92, -74;
/M: SY='D';  M= -47, -92,  85, -25, -97, -78, -70, -42, -31, -94,  14,  78,  35, -71, -79, -31,  -2, -90,-110, -88;
/I:         I=-12; MI=0; MD=-31; IM=0; DM=-31;
/M: SY='L';  M= -88,   9,-104, -97,  53, -35, -92,  21, -95,  58,   0, -99,  17, -94, -27, -94, -84, -18, -87, -69; D=-12;
/I:         I=-12; DM=-31;
/M: SY='D';  M=  10, -98,  84, -10,-104,  45, -80, -34, -79,-100, -95,   6, -89,  16, -86, -73, -81, -95,-108, -93; D=-12;
/I:         I=-12; DM=-31;
/M: SY='N';  M= -26, -95,  13,  32, -22, -87,  24,  -3,  52, -91, -85,  52, -88, -69, -13,  11, -76, -31,-102, -85; D=-12;
/I:         I=-12; DM=-31;
/M: SY='I';  M= -39, -90,   2, -91, -69, -98, -92,  80, -91,  24,  49, -88, -92, -87, -93,  -2, -74,  32, -94, -75;
/M: SY='V';  M= -15, -87,  -7, -92, -72,-100,-100,  58, -92, -57, -60, -91, -94, -92, -94, -83, -70,  89,-101, -79;
/M: SY='I';  M= -78, -93,  41,  38, -83, -89,  24,  44,  -9, -76,  -6,   6, -84,  31, -26,   1,  14,  -2, -96,   4;
/M: SY='I';  M= -86, -92,-104,-100,  80,-105, -94,  82, -96,  24, -56, -95, -97, -96, -96, -92, -79, -26, -77, -57;
/M: SY='E';  M= -76, -94,  11,  55, -96,  21,  -2, -94,  17, -56, -84,  32, -83,  48,  34, -25,   3, -43, -98, -85;
/M: SY='P';  M= -39, -96,   6,   9, -21, -84,  -9, -89,  17, -24, -80,   8,  67,  55,  30,  13, -31, -89, -93, -12;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='K';  M= -78,  34, -74,   6, -93,   9,  25, -94,  60, -27, -80,   3, -86,  43,  55,  -5, -77, -91, -95, -82;
/M: SY='E';  M= -34,  52, -69,  60,   6, -88,  31,   3,   0, -26, -77,  10, -84, -68,   4,  18,  24, -78, -93,  -6;
/M: SY='C';  M=  10,  92, -98, -94, -73, -96, -96,  43, -92, -39, -65, -91, -97, -93, -94, -81, -73,  72, -97,  13;
/M: SY='I';  M=  -9, -88, -17,  35,   2, -85, -81,  44, -25, -24,  -5,  28, -84, -73, -81,  40,  32, -11, -95, -78;
/M: SY='V';  M= -73, -86, -99, -93,   8, -99, -98,  15, -91,   5, -60, -94,   0, -92, -93, -10, -70,  91, -98, -75;
/I:         I=-30; MD=-77;
/M: SY='Y';  M= -92,-103, -90, -92, -41, -98, -58, -78,  -9, -75, -71, -91,-103, -80, -80, -86, -86, -83, -49, 133; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='P';  M= -11,-101,  35,  18,-101,  -2, -81, -93, -15, -98, -13, -18, 105, -75, -84, -24, -75, -93, -99, -95;
/M: SY='D';  M= -80,  45,  88,  24, -86, -84, -72, -88, -74, -37, -86,  20,  -3, -72, -81,  10, -14, -19, -99,  35;
/I:         I=-26; MI=0; MD=-65; IM=0; DM=-65;
/M: SY='D';  M= -41,  -2,  69,  57, -88,  -8,  13, -25, -73, -38, -80, -69, -84,  17, -79, -13, -75,  26,-100,   1;
/M: SY='S';  M= -19, -90,  13,  26, -85,   1, -77,  -2, -74, -47, -79, -16,   9,  34, -79,  51,  32, -13, -93,  20;
/I:         I=-21; MI=0; MD=-53; IM=0; DM=-53;
/M: SY='Q';  M= -80,   2,  16,  23, -87, -88,  22, -79,   8,  24, -75,  36, -23,  49, -75,  15, -34,  -2,-102, -83; D=-21;
/I:         I=-21; DM=-53;
/M: SY='K';  M= -81,  16, -77, -67, -96, -89, -80, -90,  96, -93, -84,   6, -14, -65,   7, -33, -26,  -3, -96, -86; D=-21;
/I:         I=-21; DM=-53;
/M: SY='P';  M= -83,-107,  24, -70,-102, -85, -86, -35, -80, -99, -88, -85, 124, -82, -91, -31, -76, -93, -98, -98;
/M: SY='P';  M=   6,-100,  11,   6, -97, -29, -81, -90,  19, -95, -85, -79, 101, -16,  -2, -25, -75, -41, -95, -19;
/M: SY='V';  M= -39,  -2, -89, -22, -15, -94, -87,  27, -24,  25,   2, -17,   0,   2,  12,  -5, -73,  58, -95, -77;
/M: SY='G';  M= -67, -93, -80, -91, -99, 101, -87,-105, -85,-102, -92,  -6, -85, -83, -93, -14,  -7, -98, -93, -94;
/M: SY='E';  M= -19,  16, -68,  57, -35, -86,  -3, -79,  23, -47,  -1,  11, -83,  55, -69,  12,  13,  14, -95, -23;
/M: SY='G';  M= -35, -94, -77,  -9, -99,  89, -84,-104,  46,-100, -90, -68, -84, -74, -21, -10, -81, -97, -92, -91;
/M: SY='L';  M= -84, -87,-102, -94, -59,-103, -85, -14, -95,  92,  33,-100,-101, -87, -92, -94, -80, -56, -89, -71;
/M: SY='N';  M= -80, -85, -55, -75, -91, -69, -61, -89, -67, -30,  -2, 126, -91, -68, -75, -63, -65, -92,-112, -88;
/M: SY='V';  M= -75, -89, -84, -74, -82, -93, -83, -33,  58, -20, -70, -77, -88,  18,  42, -27,  15,  63, -97, -80;
/M: SY='P';  M= -39, -99,  -8,  19, -25, -85, -78, -93,  10, -95, -85, -76,  89,   1,  52,  22, -24, -91, -95, -87;
/M: SY='A';  M=  88,  54, -84, -79, -92, -70, -86, -84, -80, -85, -80, -76, -85, -77, -85,  21,  25, -72, -97, -89;
/M: SY='R';  M= -77, -91, -77,  39, -82, -94, -81,   7,  -1,   7, -71, -77,   2, -16,  54, -74,  53,  21, -97, -81;
/M: SY='I';  M= -78, -91, -98, -13, -69,-105,-101,  92, -93, -30, -56, -93, -92, -91, -96, -88, -73,  61, -95, -76;
/M: SY='T';  M= -71, -82, -76, -14, -80, -87, -81, -74, -72, -42,  -9, -68, -80, -75,  17,   7, 103,  -9, -97,  13;
/M: SY='L';  M= -83,  10,-101, -95,  16,-102, -86, -21, -94,  79,  33, -98,-100, -89, -92, -92, -79,  21, -86,   0;
/M: SY='E';  M= -40, -94,   0,  66,  23, -90,  18, -82,  38, -25, -77,  13, -85, -65,  -9, -77, -77, -12, -81,  56;
/M: SY='N';  M= -34,  16,  -7, -76, -12,  43,  26, -87, -13, -39, -81,  83, -90,  23,  11, -69, -74, -10, -99, -82;
/I:         I=-28; MD=-71;
/M: SY='C';  M= -77, 101, -95, -92, -86, -95, -96,  10, -90, -76, -14, -24, -10,   5, -95,  26, -27,  54,-110, -90; D=-28;
/I:         I=-28; MI=-71; MD=-71; IM=-71; DM=-71;
/M: SY='W';  M= -38,-103, -15, -92,  40, -21, -94,  24,  10, -78, -80, -93, -98, -88, -27, -90, -29, -12, 127,  35; D=-28;
/I:         I=-28; DM=-71;
/M: SY='P';  M= -81, -10, -19, -73, -98,  -8, -86, -92,  18, -99, -88, -82, 114, -80, -83, -34,   0, -94,  48, -92;
/M: SY='K';  M= -13, -90, -27, -78, -29, -36, -80,  30,  40,  15, -68,  -7, -88, -73,  37, -16,  30,  -5, -89,  13;
/M: SY='D';  M=  -9, -91,  70,  -7, -96,  19, -73, -92, -31, -24, -86,  63,  -7,  17, -78,  16, -19, -90,-104, -87;
/M: SY='K';  M= -40, -94,   5,   3, -11, -24, -76,  -1,  66, -37, -78, -71, -86,   1,  58,  -8, -28, -38, -90, -11;
/M: SY='S';  M=  -6, -90,  30,  16, -89, -83, -78, -21,  34, -84,   8,   4,  11,   4,  -2,  36,   6,  13,  21, -83;
/M: SY='T';  M= -76, -88,  41,  23, -18,   7, -76, -25,   4, -24, -80,  50, -83, -72, -77,  -7,  61, -38, -98, -16;
/M: SY='R';  M= -20, -92, -14,  -1,  -7,  10,  32, -83,  38, -23, -77,  34, -88,   0,  49, -29, -35,   2, -92,   0;
/M: SY='D';  M=  -5, -93,  53,  37, -93,  12, -77, -23,  46, -25, -82, -67, -83,   9,   3,  12, -34, -46, -97, -85;
/I:         I=-9; MD=-23;
/M: SY='P';  M=  -5,-103, -29, -86, -85, -45, -12,  32, -89, -19, -79, -22,  66,  17, -93,  -2, -30, -43,  15,  29; D=-9;
/I:         I=-9; MD=-23;
/M: SY='I';  M= -26,-100, -32, -93, -31,-103, -98,  66,  -6, -19, -72, -92, -99, -88,  26,   8, -82,  19,-102, -85; D=-9;
/I:         I=-9; MD=-23;
/M: SY='K';  M= -92,-107, -23, -12,-105,-102, -91, -33,  48, -56, -92, -23,  29,  16,  20, -85,  31, -39,-110, -98; D=-9;
/I:         I=-9; MD=-23;
/M: SY='D';  M=-102,-119,  62,  28,-115, -19,  -6,  -7, -89, -54,-104, -86, -19, -16,   0, -96, -98,-105,-124,-105; D=-9;
/I:         I=-9; MD=-23;
/M: SY='P';  M= -30,-119, -15,  -9,  18, -30,-105, -38,-100,-108,-104, -29,  70, -22,-108, -96,  -5,-105,-112,-101; D=-9;
/I:         I=-9; MD=-23;
/M: SY='Q';  M=-100,-115, -92,  -2,-118,-106, -97,-114,  27, -53,-105,  24, -33,  35, -31,   1,  10,-111,-121,-108; D=-9;
/I:         I=-9; MI=0; MD=-23; IM=0; DM=-23;
/M: SY='P';  M=   9,  -4,   2, -21,-112, -19,-102, -13,-100, -50,  22,   8,  40, -10,-106, -95, -97, -99,-120,-109; D=-9;
/I:         I=-9; DM=-23;
/M: SY='K';  M= -96,-111, -33, -89,-100, -16, -95,   6,  44, -24, -91, -91,-105, -19,  40, -37, -19, -45,-107, -14; D=-9;
/I:         I=-9; DM=-23;
/M: SY='Y';  M= -21,-105,-103, -23,  50,-107,   2, -33, -95,   5, -78,-101,-109,   9, -30, -96, -93,  -1,  20,  64; D=-9;
/I:         I=-9; DM=-23;
/M: SY='E';  M= -18,-105, -26,  43,-102,-100,  11,   2,  36, -95, -90, -83, -94,   5,  31,  -5, -86, -18,-107, -93; D=-9;
/I:         I=-9; DM=-23;
/M: SY='K';  M=  -1,-104, -85, -10, -98, -45, -84,-101,  46, -35, -90,   7, -97,  31,  44, -33, -31, -97,-100,   8; D=-9;
/I:         I=-9; DM=-23;
/M: SY='H';  M= -51,-101, -81, -20,  37, -94,  87, -96,  55, -89, -12,  17, -94,  27, -19, -82, -86, -96,  25, -21; D=-9;
/I:         I=-9; DM=-23;
/M: SY='L';  M= -87, -95,-109,-103, -69,-111,-100,  53,-102,  63, -57,-105,-104, -97,-101, -98, -83,  36, -99, -80; D=-9;
/I:         I=-9; DM=-23;
/M: SY='K';  M= -40,-104, -14,  51, -97, -96, -77, -25,  53, -95, -87, -77, -89,  53,  39, -80, -84, -94, -95,  12; D=-9;
/I:         I=-9; DM=-23;
/M: SY='R';  M=   4, -97, -80, -27, -30, -16, -78, -97,  34, -58, -85,   6, -91,  35,  73,  -3, -12, -92, -97, -85; D=-9;
/I:         I=-9; DM=-23;
/M: SY='L';  M= -39, -94, -93, -87,  26, -97, -81, -24,  -7,  51, -64,  -5,-100,  39, -84,  -9, -81,  -6, -83,  46; D=-9;
/I:         I=-9; DM=-23;
/M: SY='C';  M=   3,  90, -79, -27, -90, -86,  -4, -30,  63, -85, -80, -71, -86, -16, -17, -11,  53, -27,-100, -85;
/M: SY='E';  M=  35, -90, -24,  50, -95, -80, -74, -91,  42, -42, -82,  21, -82,  35,  20,  20, -27, -85, -96, -85;
/M: SY='K';  M= -76, -92,  12,   9, -88, -30, -76,   0,  54, -48,  41, -10, -84,  35,  30,  10,   3,  -2, -96, -81;
/M: SY='K';  M=   9, -91, -73,   9, -90, -83,  10, -83,  55, -27,  53,  25,  30,  43, -25, -18,  12, -82, -95, -82;
/M: SY='G';  M= -11, -93,  54,  -5, -93,  65, -76, -94,   3, -95, -88,  48, -86, -74, -12, -69, -77, -16, -97,  -4;
/M: SY='A';  M=  58,  48, -84, -81, -85, -32, -85,   2,  -8, -32,  44, -13, -10, -79, -83, -20,  52, -26, -97, -84;
/M: SY='E';  M= -78, -94, -15,  63, -91, -48,  55, -94,  43, -90, -82, -68, -80,  23,  36, -70,  43, -89, -95,  -3;
/M: SY='F';  M= -91, -90,-103, -99, 118,-100,   3, -22, -95, -25, -66, -93,-102,-101, -92, -91, -84, -24, -60,  25;
/M: SY='I';  M= -76, -90, -87,  31, -73,-101, -93,  66,  -5, -11,  13, -88, -89, -81, -86, -83, -16,  65, -97, -78;
/M: SY='S';  M= -67,  34,  47,  12, -95,  16, -76, -96, -30, -97, -90,  10, -83, -68, -17,  83, -64, -90,-103, -87;
/M: SY='Y';  M= -40, -96, -91, -92,  45, -96,  18,   4, -86, -20, -65, -89,-100, -82, -83, -84, -82, -73, -52, 123;
/M: SY='D';  M= -82, -95,  94,  14,-100, -82, -70, -99,   5, -98, -92,  46, -84,   9,  28, -36,   0, -95,-109, -86;
/I:         I=-24; MD=-61;
/M: SY='P';  M= -16,-103, -89, -24,   9, -93, -83, -35, -32, -26, -81, -89,  82,  16,  18, -24, -28, -33, -87,  43; D=-24;
/I:         I=-24; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='E';  M= -17, -98,  42,  57, -93, -89,  22,  25,   0, -87, -84,  12, -87,  -1, -78,  15, -77, -36,-103, -18; D=-24;
/I:         I=-24; DM=-61;
/M: SY='T';  M= -74, -86,  -4, -34, -91, -40, -74, -84,  17, -89, -82,  63, -83,   3,  27,  11,  77, -28,-103, -84;
/M: SY='G';  M= -70, -95, -83, -87,  14,  94, -85,-101,  -1, -96, -88, -70, -87,  -3, -19, -31, -84, -97,  24, -24;
/M: SY='T';  M= -32, -87,  -4,  31, -83, -86, -84,  -8, -10, -44, -76, -73, -82,  -2, -79,  28,  70,  27,  70, -79;
/M: SY='W';  M= -90,  17,-109, -97,  41, -94, -94, -79, -90, -78, -81,-104, -99, -90, -91, -94, -94,  -8, 160,  65;
/M: SY='V';  M= -41,  10, -85, -81, -80, -90, -88,  12,  10, -69,   0, -77, -87,  10, -26,  15,  62,  63,-101, -81;
/M: SY='F';  M= -90, -90,-103, -99, 116,-100, -82, -18, -94, -59, -67, -94,-102,-101, -92, -90, -83,   0, -59,  50;
/M: SY='R';  M= -79, -93,  29,  31, -27, -90, -76, -25,  53, -82,  20, -70, -84,  -7,  57, -34,  19,   7, -96, -80;
/M: SY='V';  M= -70, -84, -97, -92, -72, -99, -98,   5, -90, -23,   7, -91, -94, -91, -92, -21,  16,  96,-103, -79;
/M: SY='P';  M= -82, -96,  45,  41,  38, -85, -74, -89,  26, -89, -85,  48,  62,  16, -73, -37, -75, -39, -93, -78;
/M: SY='H';  M= -86, -98,  38,  -4, -85, -88, 141, -98, -75, -86, -74, -61, -87, -66, -72, -76, -83, -36,-114,  -6;
/M: SY='F';  M= -34, -90,-100, -96, 112, -35, -85, -67, -92, -63,  -8, -91,   9, -98, -92, -19, -81,  -8,  41,  -4;
/I:         E1=0; IE=-255; DE=-255;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	14 in 14 different sequences
Number of true positive hits	14 in 14 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	Peptidase S59
Version [info]	4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

14 sequences

NU100_YEAST (Q02629), NU116_YEAST (Q02630), NU145_CHATD (G0SAK3),

NU145_YEAST (P49687), NU189_SCHPO (Q9UTK4), NU98A_ARATH (Q8RY25), 
NU98B_ARATH (F4ID16), NUP96_ARATH (Q8LLD0), NUP98_CAEEL (G5EEH9), 
NUP98_DICDI (Q54EQ8), NUP98_DROME (Q9VCH5), NUP98_HUMAN (P52948), 
NUP98_MOUSE (Q6PFD9), NUP98_RAT   (P49793)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

15 PDB

1KO6; 2AIV; 2Q5X; 2Q5Y; 3KEP; 3KES; 3PBP; 3TKN; 5CWW; 5HB5; 5HB6; 7F60;
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