PROSITE entry PS51422

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51422
Entry name [info]	SAR1
Accession [info]	PS51422
Entry type [info]	MATRIX
Date [info]	01-DEC-2008 CREATED; 10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51417
Associated ProRule [info]	PRU00756

Name and characterization of the entry

Description [info]

small GTPase SAR1 family profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=179;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=174;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-2.7613292; R2=0.0039843; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-12354.1425781; R2=27.9933796; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=2827; H_SCORE=66783; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=2325; H_SCORE=52730; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-18; D=-40; I=-40; I0=-18; B1=*; E1=*; MI=-210; MD=-210; IM=-210; DM=-210;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-210; BD=-210;
/M: SY='L';  M= -31, -43, -39, -47,   6, -75, -38,  14, -44,  64,  13, -46, -65, -32, -48, -37, -24,   4, -37, -22;
/M:
/M: SY='L';  M= -37, -45, -81, -64,  28, -84, -39,  13, -59,  65,  19, -57, -71, -42, -58, -46, -29,  -4,  18,  -8;
/M: SY='W';  M=   5, -29, -49, -31,  15, -58, -19,  -4, -28,   1,  11, -29, -50, -17, -33,  11,  -3,  -1,  75,  56;
/M: SY='K';  M= -20, -69,  -8,   6, -68, -49,  -8, -57,  55, -54, -32,  50, -42,  45,   5,  -5, -13, -46, -61, -16;
/M:
/M: SY='E';  M= -17, -69,   9,  40, -68, -45,  20, -58,  19, -55, -32,  37, -40,  13,  -9,  34,  17, -46, -64, -44;
/M: SY='A';  M=  56, -33, -32, -29, -69,  55, -39, -55, -35, -61, -41, -21, -38, -25, -42,   2,  -5, -37, -73, -62;
/M: SY='K';  M= -30, -70, -26,  -8, -75, -56, -11, -60,  82, -56, -36, -12, -49,  10,  32, -20,   0, -51, -62, -50;
/M: SY='I';  M= -44, -48, -95, -78, -19, -98, -66,  70, -73,  49,  29, -75, -83, -58, -73, -62, -36,  17, -54, -47;
/M: SY='V';  M= -31, -40, -74, -57, -15, -78, -43,  12, -51,  49,  13, -53, -67, -39, -53, -41, -24,  57,   1, -27;
/M: SY='F';  M= -44, -51, -83, -70,  94, -87, -32,  25, -65,   9,   7, -60, -76, -49, -64, -51, -37,  -4, -16,  11;
/M: SY='L';  M= -45, -51, -93, -76, -17, -97, -65,  34, -71,  70,  18, -74, -82, -56, -71, -62, -38,  20, -53, -46;
/M:
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M:
/M: SY='D';  M= -32, -80,  98,  11, -87,  -3, -24, -81, -22, -79, -61,   1, -46,  -5, -41, -18, -29, -67, -84, -64;
/M:
/M:
/M:
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M:
/I:         I=-7; MI=0; MD=-36; IM=0; DM=-36;
/M: SY='T';  M=  -4, -34, -33, -29, -61, -33, -37, -41, -29, -51, -34, -22, -40, -22, -35,  14,  93, -28, -67, -54;
/M:
/M:
/M:
/M: SY='H';  M=  -5, -59, -13,   2, -55, -15,  95, -44,   8, -44, -23,  -6, -43,  14,  27,  -9, -11, -35, -54, -19;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='M';  M= -19, -39, -41, -22, -28, -59, -21, -10,   3,   7, 103, -24, -50,  -9,  12, -19, -11,  -1, -38, -27;
/M:
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='K';  M=  -7, -63, -21,  -4, -65, -52, -12, -50,  79, -49, -29, -10, -46,   9,  15,  -6, -15,  -9, -59, -45;
/M: SY='D';  M= -26, -82,  81,  20, -81, -43, -15, -72,  -7, -69, -47,  44, -43,  14, -24, -12,  21, -59, -78, -56;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='D';  M= -28, -86,  77,  34, -86,  19, -16, -77,  -9, -73, -52,  30, -43,   5, -28,   3, -23, -64, -82, -58;
/I:         I=-10; MI=0; MD=-50; IM=0; DM=-50;
/M: SY='R';  M= -10, -69, -20,  -3, -72, -54, -10, -58,  30, -55, -33,   0, -47,  26,  80,   8, -18, -48, -61, -48;
/M: SY='L';  M= -34, -42, -82, -64, -19, -85, -52,  22, -60,  59,  53, -60, -72, -46, -61, -47,  -3,  37, -46, -39;
/I:         I=-8; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='A';  M=  37, -49, -17,  -1, -47,  12,  16, -34,  15, -36, -16,  -8, -42,   5, -15,  13,   7,  10, -50, -35;
/M: SY='Q';  M= -14, -11, -21,  -4, -44, -49, -14, -16,  -3, -33, -14, -10, -43,  78, -15,  16,  31,   5, -48, -34;
/M: SY='H';  M= -23, -48, -33, -17, -12, -59, 107, -24, -12,   3, -10, -20, -51,  -6, -20, -19, -16,   1, -25,  17;
/I:         I=-3; MI=0; MD=-14; IM=0; DM=-14;
/M: SY='Q';  M=  -3, -46,  -7,   6, -40, -51, -13,   6,  -3, -21, -10, -10, -43,  54,   2,  -9,   9,  36, -45, -31;
/M:
/M:
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='L';  M= -21, -35, -53, -35,  15, -64, -25,  -5, -32,  52,   8, -34, -55,  40, -36, -24, -13,   2,  46, -10;
/M: SY='H';  M= -20, -60, -16,   0, -50, -34, 103, -44,   8, -44, -24,  -7, -45,  30,  18, -12, -13, -36, -51,  14;
/M:
/M: SY='T';  M= -16, -55, -10,   1, -55, -46,  54, -45,  -1, -46, -25,  31, -43,   4, -13,  -1,  72, -35, -57, -40;
/I:         I=-5; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='S';  M=  16, -38, -32, -19, -50, -40, -26, -32, -18, -39,  18, -18, -42, -10, -27,  77,   5, -13, -56, -43;
/M: SY='E';  M= -32, -83,  13,  92, -81, -46, -18, -72,  -7, -69, -51,   0, -47,  22, -20, -18, -27, -62, -78, -57;
/M: SY='E';  M= -27, -81,  20,  83, -81, -44, -15, -71,  -5, -68, -46,   3, -44,  31, -21,  10, -21, -59, -76, -55;
/M: SY='L';  M= -51, -57, -96, -80,  19,-101, -60,   8, -75,  77,  30, -76, -84, -56, -73, -65, -43,  -4, -43, -31;
/M: SY='T';  M=  17, -36, -34, -20, -46, -41, -26, -28, -16, -36, -17, -19, -42, -11, -29,  47,  53,  26, -52, -40;
/M: SY='I';  M= -30, -37, -80, -62, -16, -79, -45,  66, -57,  35,  52, -56, -68, -42, -57, -41, -22,  16, -39,  15;
/I:         I=-4; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='G';  M=  24, -47,  -8,  11, -67,  67, -26, -54, -18, -57, -37, -10, -41,  -9, -29,  -6, -12, -40, -69, -54;
/I:         I=-10; MI=0; MD=-54; IM=0; DM=-54;
/M: SY='N';  M= -19, -68,  -2,   8, -70,  26, -11, -59,  38, -56, -34,  62, -42,  14,   0,   7, -13, -47, -65, -47;
/M: SY='M';  M= -39, -43, -94, -78, -27, -94, -65,  68, -74,   8,  82, -72, -81, -59, -74, -57, -32,  49, -56, -48;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='K';  M= -21, -69, -15,   2, -70, -51, -10, -57,  51, -54, -32,  31, -44,  12,  49,  -4,  42, -47, -62, -46;
/M: SY='F';  M= -46, -53, -89, -74,  98, -92, -38,  11, -69,  22,   9, -65, -79, -52, -68, -55, -39,   3, -22,   3;
/M: SY='T';  M= -21, -61, -16,  -3, -66, -49, -15, -51,  60, -52, -31,   4, -45,   5,  -2, -12,  70, -42, -62, -47;
/I:         I=-11; MI=0; MD=-56; IM=0; DM=-56;
/M: SY='T';  M=  47, -34, -43, -35, -63, -35, -41, -39, -36, -51, -34, -26, -42, -27, -42,  -2,  85, -27, -70, -59;
/M: SY='F';  M= -53, -57, -86, -75, 100, -90, -12,  -2, -70, -17, -14, -55, -79, -49, -66, -53, -46, -28,   7,  68;
/I:         I=-10; MI=0; MD=-52; IM=0; DM=-52;
/M:
/I:         I=-9; MI=0; MD=-45; IM=0; DM=-45;
/M:
/M:
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M:
/M: SY='H';  M= -34, -70, -12,  -7, -41, -55, 125, -59,   1, -55, -39, -13, -52,  28,  -5, -24, -27, -52, -47, -24;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='Q';  M=  11, -57, -12,  45, -54, -47, -10, -14,   4, -25, -21,  -4, -17,  47,   0,   0,  17,  -6, -54, -37;
/M: SY='Q';  M=  -8, -56, -14,   8, -52, -50, -11,   5,   2, -40, -19,  18, -21,  80, -11,   1,  20, -10, -53, -37;
/I:         I=-10; MI=0; MD=-50; IM=0; DM=-50;
/M: SY='A';  M=  75, -38, -49, -37, -43, -49, -39,  -7, -34,  -3, -14, -32, -51, -26, -40, -15, -13,  13, -57, -45;
/M:
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='R';  M= -27, -66, -26,  -6,  -5, -57, -11, -51,  31, -49, -29, -12, -48,  24,  85, -17, -18, -43, -57, -43;
/M: SY='V';  M=  -3, -37, -75, -58, -30, -79, -49,  33, -55,  35,   2, -54, -69, -44, -58, -41,   5,  64, -50, -39;
/M:
/M: SY='K';  M= -36, -79, -29,   6, -85, -61, -12, -69,  88, -62, -42, -15, -52,  10,  42, -25, -26, -60, -65, -55;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='D';  M= -25, -82,  69,  14, -81, -44, -14, -72,  -4, -68, -46,  63, -43,  51, -21, -12,   2, -59, -77, -55;
/M:
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='F';  M= -19,  29, -72, -53,  61, -66, -30,   9, -48,  30,  12, -44, -57, -33, -46, -28, -12,  25, -25,  35;
/M: SY='P';  M=  30, -37, -31, -22, -65,  -8, -33, -52, -26, -56, -35, -19,  86, -16, -35,  -1,  30, -36, -69, -56;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='A';  M=  41, -70,  18,  34, -69, -46, -10, -59,  28, -56, -32,  28, -41,  18, -10,   9,   5, -47, -65, -45;
/I:         I=-3; MI=0; MD=-13; IM=0; DM=-13;
/M: SY='V';  M= -25, -36, -71, -55, -33, -72, -48,  52, -52, -12,  -3, -50, -66, -41, -55,  10, -20,  72, -51, -39;
/M: SY='D';  M= -29, -87,  79,  15, -86, -44, -17, -78,  13, -73, -52,  67, -44,   4, -27,  -4, -23, -64, -82, -59;
/M: SY='G';  M=  49, -34, -38, -33, -71,  65, -42, -57, -37, -63, -42, -24, -39, -27, -44,   1,  20, -38, -75, -64;
/M: SY='I';  M= -42, -45,-101, -87, -38,-102, -80,  80, -84,   2,  -3, -81, -89, -72, -85, -67, -36,  64, -71, -60;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='V';  M= -38, -44, -91, -78, -39, -91, -73,  38, -74,  -6,  -6, -73, -83, -65, -77, -57, -33,  90, -69, -57;
/M: SY='F';  M= -68, -68, -91, -87, 103, -97,  -7, -43, -81, -30, -29, -58, -86, -55, -74, -62, -60, -45,  15,  81;
/M: SY='L';  M= -50, -54,-102, -84, -15,-104, -70,  34, -80,  71,  63, -81, -86, -60, -78, -67, -42,   7, -53, -49;
/M: SY='V';  M= -40, -44, -97, -83, -40, -97, -77,  52, -80,  -6,  -5, -78, -87, -69, -82, -63, -34,  86, -71, -59;
/M:
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='C';  M=  53,  81, -53, -41, -51, -35, -39, -35, -39, -42, -23, -29, -41, -28, -44,  44,  10, -14, -59, -49;
/M: SY='A';  M=  49, -38, -30, -13, -16, -54, -17, -16,  -4, -19,  -3, -17, -46,  -4, -22,  29,  13,  -2,  21,   7;
/M: SY='D';  M=   0, -77,  97,  12, -84, -42, -21, -74, -16, -73, -53,  11, -45,  -2, -34, -15, -10, -60, -83, -61;
/M: SY='H';  M= -11, -61, -12,   5, -30, -49,  63, -46,  21, -46, -24,  -3,  30,  28,  40,  -4,  -8, -31, -57,  12;
/M: SY='E';  M=  -9, -29,  16,  61, -69, -23,  -9, -59,   6, -56, -32,  33, -40,  26, -10,  27,   0, -47, -65, -45;
/I:         I=-7; MI=0; MD=-38; IM=0; DM=-38;
/M: SY='R';  M= -29, -64, -34, -17, -72, -54, -18, -62,  14, -59, -41, -19, -51,   1,  97,   7, -24, -52, -63, -52;
/M: SY='F';  M= -46, -51, -96, -79,  80, -96, -54,  26, -75,  50,  28, -73, -81, -55, -72, -59, -38,  -2, -39, -25;
/M: SY='Q';  M=  14, -58,   8,  20, -54, -25, -10,  -9,  11,   1,  -7,  13, -16,  42, -10,   4,  -8,  -7, -54, -38;
/M:
/M: SY='S';  M=  37, -34, -39, -32, -70, -31, -40, -56, -35, -62, -41, -23, -39, -25, -42,  84,  13, -37, -74, -63;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='K';  M= -21, -76, -30,  -9, -82, -60, -11, -67,  81, -61, -40,   1, -51,  10,  55, -23, -24, -58, -65, -54;
/M: SY='E';  M=  -4, -61, -11,  38, -58, -48,  -9, -18,  33, -46,  -6,  11, -41,  19,  26,  16,  -8,   5, -57, -12;
/M: SY='E';  M= -25, -73,   1,  86, -74, -48, -14, -62,   3, -61, -40,  -3, -45,   6,  16, -14,   1, -52, -69, -52;
/M: SY='L';  M= -38, -46, -82, -65,  -2, -87, -53,  26, -60,  71,  15, -62, -74, -46, -62, -49,   6,   6, -47, -38;
/I:         I=-6; MD=-29;
/M: SY='D';  M= -16, -76,  72,  25, -75, -45,  29, -66,  12, -62, -38,  23, -41,  26,   7,  -3, -13, -53, -70, -49; D=-6;
/I:         I=-6; MD=-29;
/M: SY='S';  M=  33, -63,  14,  17, -61, -47,   9, -49,  12, -48,   9,  11, -40,  26,  -9,  40,  -8, -39, -59, -41; D=-6;
/I:         I=-6; MD=-29;
/M: SY='L';  M= -50, -54, -97, -81, -16,-101, -68,  39, -74,  74,  18, -78, -85, -59, -74, -66, -42,   7, -53, -46; D=-6;
/I:         I=-6; MD=-29;
/M: SY='L';  M= -49, -53,-100, -82,  19,-101, -64,  23, -78,  70,  62, -78, -83, -57, -75, -64, -40,  -2, -47, -42; D=-6;
/I:         I=-6; MD=-29;
/M: SY='Q';  M=   5, -67,  11,  20, -66,  -8,  -9, -56,   5, -54, -30,  36, -40,  44, -10,  26,  31, -44, -63, -44; D=-6;
/I:         I=-6; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='D';  M=   0,  -1,   1,   0,  -1,  -1,   0,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   0,  -1,   0; D=-6;
/I:         I=-6; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='E';  M=   0,  -1,   0,   1,  -1,  -1,   0,  -1,   0,  -1,   0,   0,   0,   0,   0,   0,   0,  -1,  -1,  -1; D=-6;
/I:         I=-6; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='E';  M=   4, -66,   7,  52, -65, -46,  26, -54,   7, -52,  -4,   0, -39,  34,  13,   8,  28, -43, -60, -42;
/M: SY='L';  M= -49, -53,-102, -85,  17,-102, -67,  48, -81,  69,  19, -80, -85, -61, -78, -66, -41,   7, -50, -42;
/I:         I=-9; MI=0; MD=-45; IM=0; DM=-45;
/M: SY='A';  M=  40, -55,  -9,  10, -51, -39, -11, -38,  20, -20, -19,  -5, -42,  13, -12,  37,  13, -30, -53, -14;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='N';  M= -17, -70,  18,  10, -70, -36,  19, -59,  19, -56, -32,  69, -40,  39,  -1,   6,  23, -47, -65, -45;
/I:         I=-3; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='V';  M=  -7,  20, -44, -27, -27, -54, -24,  -2,  -3, -17,   0, -26, -48, -15, -31,   7,  29,  58, -37, -25; D=-3;
/I:         I=-3; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='P';  M= -38, -60, -46, -48, -79, -52, -56, -76, -53, -76, -65, -46, 121, -47, -56, -35, -41, -64, -73, -71; D=-3;
/I:         I=-3; DM=-17;
/M: SY='F';  M= -37, -43, -91, -73,  68, -89, -53,  54, -69,  26,  14, -67, -76, -52, -68, -52, -30,  30, -42, -31; D=-3;
/I:         I=-3; DM=-17;
/M: SY='L';  M= -33, -46, -88, -72, -23, -91, -62,  24, -67,  62,  11, -68, -79, -54, -69, -55, -33,  51, -55, -46; D=-3;
/I:         I=-3; DM=-17;
/M: SY='I';  M= -41, -45, -96, -82, -35, -98, -75,  88, -78,   4,   0, -77, -86, -67, -80, -63, -35,  45, -67, -57; D=-3;
/I:         I=-3; DM=-17;
/M: SY='L';  M= -52, -58, -92, -78,  11, -98, -58,   7, -72,  79,  18, -74, -83, -56, -71, -64, -44,  -5, -41, -26; D=-3;
/I:         I=-3; DM=-17;
/M: SY='G';  M=  -7, -39, -26, -28, -76,  84, -43, -68, -39, -72, -52, -22, -41, -29, -46,  13, -12, -47, -78, -66; D=-3;
/I:         I=-3; DM=-17;
/M: SY='N';  M= -18, -57,   0,  -2, -70, -39, -25, -66, -16, -67, -47, 102, -44,  -8, -27,  14, -18, -51, -72, -53; D=-3;
/I:         I=-3; DM=-17;
/M: SY='K';  M= -42, -74, -31, -20, -80, -59, -23, -69,  98, -65, -50, -23, -56,  -4,   6, -33, -35, -61, -67, -58; D=-3;
/I:         I=-3; DM=-17;
/M: SY='I';  M= -33,  25, -90, -74, -35, -85, -64,  86, -70,  -6,  -2, -67, -77, -59, -72, -50, -27,  39, -60, -49; D=-3;
/I:         I=-3; DM=-17;
/M:
/M: SY='R';  M=  13, -55,  -6,   2, -50, -50,   7,  28,  31, -39,  13,  13, -42,   9,  38,  -2,  -8, -29, -52, -36;
/I:         I=-5; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='P';  M= -13, -55,  -9,   2, -56, -29, -11, -44,  19, -44, -25,  -5,  72,  28,   4,  -9,   0, -36, -54, -39;
/I:         I=-12; MD=-64;
/M: SY='E';  M=   0,  -1,   0,   0,  -1,   0,   0,  -1,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   0,  -1,   0; D=-12;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='A';  M=   3,  -2,  -1,   0,  -3,  -2,   1,  -2,  -1,  -2,  -1,   0,  -2,   0,  -1,   0,   0,  -2,  -3,  -2;
/M: SY='V';  M=  33,  -4, -47, -30, -20, -57,  22,  29, -27,  -4,  21, -28, -49, -17, -32, -18,   2,  36, -31, -20;
/M: SY='S';  M=  -8, -43, -14,  -9, -68,  -8, -26, -57, -17, -59, -37,  20,   0,  -8, -28,  79,  -8, -41, -69, -54;
/M: SY='E';  M= -21, -65,  -7,  79, -63, -48, -11, -50,   6, -49,   9,  -4, -43,   9,  16, -11, -14, -41, -60, -43;
/M: SY='E';  M=   1, -80,  62,  63, -80, -26, -14, -71,  -5, -67, -46,   4, -42,  14, -22, -11, -10, -58, -75, -54;
/M: SY='E';  M= -13, -68,  -6,  59, -68, -46,   6, -58,  24, -54, -31,  21, -40,  39,  20,  -6,   5, -46, -62, -31;
/M: SY='L';  M= -50, -55, -95, -78,   2,-100, -63,  13, -73,  75,  39, -76, -83, -55, -72, -65, -42,  -2, -47, -40;
/M: SY='R';  M= -13, -13, -20,  -7, -30, -38, -11,   5,   6, -18,  -8, -10, -33,   1,  54, -10,  -8,   2, -33, -24;
/M: SY='Q';  M=   7, -59,  12,  33, -57, -39,  17, -28,   6, -45,  -3,  12, -39,  40,  -8,  17,   2, -36,   5,  19;
/M: SY='H';  M=  25, -25, -25,  -1, -33, -51,  44,  -6,  -8,   2,  31,   4, -43,   8, -19,  11,   1,  -2, -39,  -7;
/M: SY='L';  M= -46, -51, -93, -76,  55, -94, -54,   7, -71,  62,  47, -71, -78, -52, -69, -58, -38,  -5, -38, -26;
/M: SY='G';  M=   0,  -1,   0,   0,  -1,   1,   0,  -1,   0,  -1,   0,   0,   0,   0,   0,   0,   0,  -1,  -1,  -1;
/M: SY='L';  M=  -1,  -1,  -1,  -1,   0,  -1,  -1,   1,  -1,   1,   0,  -1,  -1,  -1,  -1,  -1,   0,   0,  -1,  -1;
/M: SY='Y';  M=   0,   0,   0,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   1;
/M: SY='Q';  M=   0,  -1,   0,   0,  -1,   0,   0,  -1,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   0,  -1,   0;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='Q';  M=   0,  -1,   0,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   1,   0,   0,   0,   0,  -1,   0; D=-12;
/I:         I=-12; DM=-64;
/M: SY='T';  M=   0,   0,   0,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   1,   0,   0,   0;
/M: SY='T';  M=   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,  -1,   0,   0,   0,   1,   0,   0,   0;
/I:         I=-5; MD=-24;
/M: SY='G';  M=  -1,  -2,  -1,  -1,  -3,   3,  -1,  -2,  -1,  -1,  -2,   0,  -2,  -1,  -1,   0,  -1,  -2,  -3,  -2; D=-5;
/I:         I=-5; MD=-24;
/M: SY='K';  M=  -3, -10,  -1,   1, -10,  -8,  -1,  -5,  11,  -8,  -4,   3,  -7,   2,   1,   1,  -2,  -7,  -9,  -5; D=-5;
/I:         I=-5; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='G';  M=  -4, -19,  -2,   0, -23,  21,  -1, -19,  -2, -19, -11,  -2, -16,   9,  -6,   2,  -1, -12, -24, -18; D=-5;
/I:         I=-5; DM=-24;
/M: SY='N';  M=  -1, -26,   1,   5, -25,  -9,  -3, -17,  14, -20, -11,  14, -16,  12,   5,   6,  -2, -16, -24, -17; D=-5;
/I:         I=-5; DM=-24;
/M: SY='V';  M=  -2,  -1,  -3,  -1,  -4,  -9,  -3,   5,   0,  -3,   1,   0,  -7,  -1,  -4,   0,   2,   6,  -6,  -4; D=-5;
/I:         I=-5; DM=-24;
/M: SY='N';  M=  -1,  -5,  -5,   2, -21, -18,  -4, -16,   9, -16,  -8,  14,   7,   4,  -2,  10,   5,  -7, -21, -15; D=-5;
/I:         I=-5; DM=-24;
/M: SY='L';  M=  -4,  -2, -13,  -6, -11,  -6,  -7,   3,   1,  11,   2,  -7, -18,   1,   4,  -5,  -2,   2, -14,  -9; D=-5;
/I:         I=-5; DM=-24;
/M: SY='K';  M=   1, -42,  -2,   7, -41, -24,  -5, -32,  28, -32,  -8,   7, -13,  10,  10,   6,  11, -25, -39, -27; D=-5;
/I:         I=-5; DM=-24;
/M: SY='E';  M= -15, -55,  30,  37, -54,  -4,  -7, -47,  -1, -45, -30,   9, -27,  17, -14,   0, -11, -38, -51, -36; D=-5;
/I:         I=-5; DM=-24;
/M: SY='E';  M=  -2,  -7,  -3,   4,  -6,  -8,  -2,   1,   0,   2,   1,   1,  -2,   1,   1,   2,   2,  -3,  -7,  -5; D=-5;
/I:         I=-5; DM=-24;
/M: SY='N';  M=   1,  -2,   4,   1, -10,   4,  -2,  -8,   0,  -8,  -4,   7,  -1,   2,  -2,   1,  -1,  -6, -10,  -7; D=-5;
/I:         I=-5; DM=-24;
/M: SY='Q';  M=   2,  -7,  -4,  -1,  -6,  -2,  -2,   1,  -1,  -3,   0,  -1,  -7,   6,  -3,   1,   1,   3,  -7,  -4; D=-5;
/I:         I=-5; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='R';  M=   0,  -1,   0,   0,  -1,  -1,   0,   0,   0,   0,   0,   0,  -1,   0,   1,   0,   0,   0,  -1,   0; D=-5;
/I:         I=-5; DM=-24;
/M:
/M: SY='M';  M= -36, -41, -89, -72,  14, -87, -55,  43, -68,  42,  54, -65, -73, -51, -66, -50, -28,  42, -44, -37;
/M: SY='E';  M= -31, -87,  41,  86, -86, -41, -18, -78, -13, -75, -56,   5, -44,   1, -32, -17, -27, -65, -82, -60;
/M: SY='V';  M= -37, -43, -85, -70, -26, -88, -62,  26, -65,  41,   6, -66, -77, -54, -67, -54, -31,  70, -56, -46;
/M: SY='F';  M= -43, -50, -78, -66,  94, -83, -21,  15, -61,   1,   1, -53, -72, -44, -60, -47, -36, -12,  -4,  32;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='M';  M= -23, -42, -49, -37, -27, -58, -36,  -8, -31,  -4, 118, -36,  -9, -26, -35, -25, -20,  -9, -46, -34;
/M: SY='C';  M=  -2, 117, -53, -44, -47, -34, -39, -27, -37, -38, -21, -29, -40, -30, -29,   7,  20, -17, -56, -45;
/M:
/M: SY='V';  M= -23, -36, -66, -52, -34, -68, -46,  35, -48, -12,  -4, -47, -64, -39, -52,   0, -19,  77, -52, -40;
/M: SY='V';  M= -13, -34, -72, -56, -26, -75, -45,  45, -52,  37,   4, -51, -66, -40, -54, -21, -19,  51, -45, -35;
/I:         I=-11; MI=0; MD=-56; IM=0; DM=-56;
/M: SY='K';  M= -19, -64, -15,   3, -63, -50,  -9, -50,  58, -49,  33,  27, -42,  22,  30,  -8,  12, -41, -58, -42;
/M: SY='R';  M= -36, -76, -34, -12, -82, -61, -10, -67,  53, -60, -40,  -1, -52,  11,  84, -25, -26, -58, -63, -53;
/M: SY='Q';  M= -14, -43, -18,  -2, -10, -51, -14,  -4,  -5, -26,  33,   8, -43,  71, -17,  -4,  -6,   0, -42,  21;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M:
/I:         I=-10; MI=0; MD=-54; IM=0; DM=-54;
/M: SY='Y';  M= -42, -53, -63, -52,  17, -77, -14,   9, -46, -18, -13, -43, -69, -34, -47, -41, -35, -20,   0, 112;
/M: SY='G';  M=  34, -38, -27, -14, -53,  42, -24, -39, -16, -19, -23, -15, -15,  -7, -26,   8,  28, -28, -57, -44;
/M: SY='E';  M= -14, -88,  56,  79, -87, -42, -16, -78, -11, -74, -54,   6, -43,   4, -30, -14, -24, -65, -83, -59;
/M: SY='G';  M=  32, -37, -31, -20, -51,  59, -28, -34, -20, -40,  29, -18, -41, -12, -29,  -3,  -6, -24, -57, -45;
/M: SY='F';  M= -46, -52, -87, -73,  91, -91, -37,  16, -68,  28,  12, -63, -78, -50, -66, -55, -38,  -4, -20,   5;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='R';  M= -30, -75, -24,  -4, -80, -56,  -9, -65,  51, -59, -38,  25, -48,  39,  69, -18, -20, -55, -63, -51;
/M:
/M: SY='L';  M= -37, -50, -92, -75, -15, -96, -62,  31, -70,  68,  54, -72, -80, -53, -70, -60, -37,   8, -50, -45;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='S';  M=  37,  37, -47, -36, -59, -20, -38, -45, -35, -51, -30, -25, -38, -25, -41,  74,  -2, -29, -65, -55;
/M: SY='Q';  M= -20, -68,  -6,  13, -67, -48,  10, -56,  24, -53, -31,  11, -20,  86,  -2,  -5,  11, -45, -62, -45;
/M: SY='Y';  M=   0,  -1,   0,   0,   0,  -1,   0,   0,   0,   0,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   1;
/M: SY='I';  M= -44, -48, -97, -80, -20, -99, -68,  66, -76,  53,  29, -76, -83, -59, -75, -63, -36,  22, -55, -49;
/I:         E1=0; IE=-210; DE=-210;

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Post-processing [info]

COMPETES_HIT_WITH

PS51417; PS51418; PS51419; PS51420; PS51421; PS51423; PS51424

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	50 in 50 different sequences
Number of true positive hits	50 in 50 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	1
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	98.04 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	N_Hulo, L_Cerutti
Version [info]	5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

50 sequences

SAR1A_ARATH (O04834), SAR1A_BOVIN (Q3T0D7), SAR1A_BRACM (O04266),

SAR1A_DICDI (Q559R0), SAR1A_HUMAN (Q9NR31), SAR1A_MOUSE (P36536), 
SAR1A_PIG   (Q52NJ3), SAR1A_PONAB (Q5R548), SAR1B_ARATH (Q01474), 
SAR1B_BOVIN (Q3T0T7), SAR1B_BRACM (O04267), SAR1B_CRIGR (Q9QVY3), 
SAR1B_DICDI (Q54Y14), SAR1B_HUMAN (Q9Y6B6), SAR1B_MOUSE (Q9CQC9), 
SAR1B_PIG   (Q5PYH3), SAR1B_RAT   (Q5HZY2), SAR1_ASPCL  (A1CRG9), 
SAR1_ASPFU  (Q4WJS7), SAR1_ASPNC  (P0C951), SAR1_ASPNG  (P0C950), 
SAR1_ASPOR  (Q877B9), SAR1_ASPTN  (Q0CUN7), SAR1_CAEEL  (Q23445), 
SAR1_CANAL  (Q59S78), SAR1_CANGA  (Q6FUZ9), SAR1_CHAGB  (Q2HA55), 
SAR1_CRYNB  (P0CR31), SAR1_CRYNJ  (P0CR30), SAR1_DEBHA  (Q6BVA7), 
SAR1_EMENI  (Q5BGB9), SAR1_EREGS  (Q755D7), SAR1_GIAIN  (Q8MQT8), 
SAR1_HYPJE  (P78976), SAR1_KLULA  (Q6CWR7), SAR1_KOMPG  (Q9P4C8), 
SAR1_LODEL  (A5E5G3), SAR1_MYCMD  (Q4P0I7), SAR1_NEOFI  (A1D4D1), 
SAR1_NEUCR  (P0C583), SAR1_PHANO  (Q0UKC0), SAR1_PICGU  (A5DR82), 
SAR1_PICST  (A3LTA2), SAR1_PYRO3  (P0CT17), SAR1_PYRO7  (P0CT16), 
SAR1_SCHPO  (Q01475), SAR1_TOBAC  (P52885), SAR1_YARLI  (Q6CB54), 
SAR1_YEAST  (P20606), SAR2_SOLLC  (P52884)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

1 sequence

SAR1_ENCCU  (Q8SS09)

PDB
[Detailed view]

21 PDB

1F6B; 1M2O; 2FA9; 2FMX; 2GAO; 2QTV; 4BZI; 6GNI; 6VS4; 6X90; 6ZGA; 8BSH;
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