PROSITE entry PS51419

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51419
Entry name [info]	RAB
Accession [info]	PS51419
Entry type [info]	MATRIX
Date [info]	01-DEC-2008 CREATED; 10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51417
Associated ProRule [info]	PRU00753

Name and characterization of the entry

Description [info]

small GTPase Rab1 family profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=200;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=195;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.6544935; R2=0.0043816; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=10457.1884766; R2=18.2324715; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1563; H_SCORE=38955; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1106; H_SCORE=30622; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-19; D=-40; I=-40; I0=-19; B1=*; E1=*; MI=-210; MD=-210; IM=-210; DM=-210;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-210; BD=-210;
/M: SY='D';  M= -15, -76,  39,  24, -52, -21,  10, -21,  28, -62,  -9,  11, -17,  18,   5,  23,   2, -53, -70, -52;
/M: SY='Y';  M=   1, -65,   6,  30, -10, -39, -20, -33,  14, -41,  -3,  -4,  -5,  23,   4, -16,  -8, -29, -12,  59;
/M: SY='D';  M= -11, -78,  56,  33, -78, -55, -18, -49,  20, -54, -41,  30, -14,  12,   1,  12,  12, -56, -73, -54;
/M: SY='Y';  M= -24, -51,  -8, -17, -10, -61,  39,   4,  14, -20,  19,  -1, -35,  -9,  -2,  -6, -10,  13, -50,  62;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='L';  M=  -6, -58,   8,   1, -52, -28,  -4,   5,  12,  33,  -4,   0, -52,  24, -25,  -8,  10,   2, -56, -42;
/M: SY='F';  M=  -5, -12, -71, -53,  67, -71, -13,  15, -48,  25,   8, -46, -62, -35, -49,   4, -18,   4, -36,  40;
/M: SY='K';  M= -45, -87, -40, -20, -91, -71,   3, -77,  97, -71, -51, -25, -62,   8,  26, -34, -18, -68, -75, -64;
/M: SY='V';  M= -35, -13, -90, -72,   8, -85, -53,  55, -67,  35,  16, -64, -75, -52, -66, -47, -17,  55, -48,  -8;
/M: SY='V';  M= -45, -18,-102, -85, -42,-100, -72,  60, -82,  34,   3, -79, -89, -68, -82, -64, -16,  66, -66, -57;
/M: SY='L';  M= -35, -54,-104, -86,  -2,-102, -70,  49, -83,  60,  34, -80, -88, -65, -81, -65, -42,  39, -59, -53;
/M: SY='I';  M=  -9, -14, -96, -79, -41, -95, -66,  70, -75,  37,  -9, -73, -84, -62, -76, -57, -20,  47, -62, -52;
/M:
/M: SY='D';  M= -14, -86,  82,  37, -86, -54, -22, -76,   5, -73, -50,  26, -15,  -1, -27,   9, -25, -64, -81, -30;
/M: SY='S';  M=  13, -59, -30,  -4, -53, -22, -23, -39,  -4,  -8,  19, -19, -32,  21,  -2,  62, -10, -20,   9, -19;
/M: SY='G';  M=  30, -71,   9,  -4, -42,  45, -21, -58,   3, -58, -36,  33, -51,   0, -22,  23, -11, -48, -69, -24;
/M: SY='V';  M= -18,  -4, -78, -64, -51, -67, -58,   0, -61, -32, -21, -55, -68, -50, -64, -22,  25,  88, -66, -55;
/M:
/M:
/M: SY='T';  M= -14, -46, -45, -37, -78, -23, -47, -64, -40, -69, -48, -32, -50, -31, -48,  66,  85, -47, -81, -69;
/M: SY='C';  M= -11,  79, -40,  -9, -60, -52, -35, -46, -27, -50, -31,  14, -53, -19, -37,  78,  -7, -36, -65, -52;
/M: SY='L';  M= -55, -59,-111, -93,  33,-109, -74,  58, -89,  63,  23, -87, -92, -69, -86, -72, -47,   8, -59, -53;
/M: SY='L';  M= -24, -43, -81, -63, -32, -82, -49,  32, -59,  53,  42, -58, -72, -46, -60,  -7, -17,  44, -49, -39;
/M: SY='H';  M= -25, -26, -28,  10,  -8, -59,  50, -28,   7,  11,   8,  19, -52,  38,   1,  10,  -1, -14,  -9,   7;
/M: SY='R';  M= -44, -83, -41, -21, -86, -70,  -2, -72,  15, -47, -47, -25, -62,  35,  99, -15, -34, -63, -72, -61;
/M: SY='Y';  M= -56, -61, -93, -80,  87, -95, -26, -18, -75,  13, -17, -63, -85, -55, -72, -58, -48, -20,  -8,  88;
/M: SY='C';  M=  -3,  53, -51, -34, -13, -65,  -4,  -1,  -6, -16,  18, -10, -58,  -1, -39,   2,  36,  45, -42, -30;
/M: SY='D';  M= -19, -26,  47,  28, -20, -56,  41, -66,  31, -51, -40,  22, -49,  22,  10,   5,   8, -54, -71, -27;
/M: SY='N';  M= -31, -87,  55,   2, -86,  25, -22, -77,  18, -73, -49,  70, -52,  18,  -5,  -7, -25, -64, -81, -60;
/M: SY='Q';  M=  -3, -73,  -1,  32, -72, -56, -18, -15,  30, -38, -36,   1, -49,  34,  24,  13,  33, -16, -69, -51;
/M: SY='F';  M= -26, -56, -81, -66, 106, -86, -24, -31, -35, -29, -19, -55, -77, -46, -61, -48, -39, -29,  44,  36;
/I:         I=-11; MI=0; MD=-56; IM=0; DM=-56;
/M: SY='S';  M=  -7, -31,  22,  12, -24, -31,  -4, -35,   1, -35, -16,  14,   0,  25,  -4,  37,  21, -32, -66, -16; D=-11;
/I:         I=-11; DM=-56;
/M: SY='E';  M= -13, -29,   6,  48, -44,  -2,  -2, -50,  20, -61, -38,  -1,  30,  26, -18,  20,  -7, -15, -70, -51;
/M: SY='N';  M=  -3, -21,  14,  27, -46, -16,  29, -66,  17, -50, -39,  37,   3,  34,  -2,  17,  15, -54, -71, -52;
/M: SY='Y';  M= -25,  19, -50, -33,  12, -67,  34,  -6, -12,   5,   7, -34, -59,  21, -25,   0,  25,   4, -43,  66;
/I:         I=-13; MD=-67;
/M: SY='K';  M=  -1, -73,  10,  24, -45, -46, -18, -13,  45, -31, -17,  -3, -18,  37,   9,   9,   1, -26, -69, -51; D=-13;
/I:         I=-13; MI=-67; IM=-67; DM=-67;
/M: SY='S';  M=  24, -31, -26,  -8, -39, -60,  25, -33,  -1, -25, -27,  11,  33,  20, -23,  41,  25, -39, -62, -12;
/M: SY='T';  M= -18, -47, -48, -38, -66, -49, -44, -46, -36, -55,  -9, -34, -54, -30, -43,  15, 102, -36, -73, -60;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='I';  M= -36, -45, -81, -63, -38, -85, -53,  81, -60,   7,  14,  -1, -76, -48, -62, -47, -16,  41, -55, -44;
/M: SY='G';  M= -22, -54, -33, -26, -65,  86, -38, -31, -27, -36, -40, -27, -54,  -5, -35,  -9, -22, -43, -71, -55;
/M: SY='V';  M=  33, -12, -68, -27, -37, -53, -44,  38, -48, -12,  -8, -48, -67, -37, -53, -36, -23,  67, -49, -38;
/M: SY='D';  M=  18, -89,  84,  37, -88, -55,  24, -79, -13, -75, -53,  -8, -53,  -3, -30,  13, -28, -66, -84, -63;
/M: SY='F';  M= -50, -10, -88, -74, 108, -91, -30, -11, -69, -13, -14, -61, -81, -52, -68, -54, -43, -24, -14,  34;
/I:         I=-11; MD=-58;
/M: SY='K';  M=   4, -61, -26,   0,  10, -21,  -3, -43,  34,  10,   3,  -9, -51,  26,  16,  12,  -2, -16, -59, -43; D=-11;
/I:         I=-11; MI=-58; MD=-58; IM=-58; DM=-58;
/M: SY='T';  M=   0,  -1,   0,   0,  -1,  -1,   0,   0,   0,   0,   0,   0,  -1,   0,   0,   0,   0,   0,  -1,   0; D=-11;
/I:         I=-11; DM=-58;
/M: SY='K';  M= -42, -86, -37,  -4, -90, -69, -21, -76,  85, -70, -49, -22, -60,   9,  54, -19,  -5, -66, -74, -62; D=-11;
/I:         I=-11; DM=-58;
/M: SY='T';  M= -19, -65,  -4,   3, -60, -58, -20, -15,   5, -40, -28,   6, -51,  19,  21,  21,  58,  13, -62, -46; D=-11;
/I:         I=-11; DM=-58;
/M: SY='I';  M= -43, -13,-101, -83,   1, -96, -65,  62, -79,  34,  43, -75, -84, -63, -77, -59, -36,  55, -57, -48;
/M: SY='E';  M= -13, -63,  -7,  40, -36, -58, -21, -18,   5,  -6,   9,  22, -51,  29, -15,   3,   8,  13, -60,  19;
/M: SY='I';  M= -15, -36, -69, -51, -26, -70, -36,  55, -32,  10,  -1, -32, -62, -11, -30, -24, -17,  53,  41,   1;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='D';  M= -27, -82,  71,  29, -81,  -3,  -2, -71,   9, -47,  -9,  41, -51,  11,   1,  -1, -20, -59, -76, -56;
/I:         I=-11; MI=0; MD=-58; IM=0; DM=-58;
/M: SY='G';  M= -27, -11,  30,  15, -75,  54, -20, -64,  -6, -62, -39,  45, -51,  10, -21,   5,  -3, -53, -72, -24;
/M: SY='K';  M= -13, -76, -11,  38, -75, -56,  -2, -17,  52, -62, -20,  13, -49,  32,  20,  -1,  18, -33, -70, -52;
/I:         I=-9; MI=0; MD=-47; IM=0; DM=-47;
/M: SY='K';  M= -18, -67,  -9,   0, -40, -58,  -3,   5,  43, -26,  -5,   6,  -3,   8,  28,   1,  37, -22, -63, -47;
/M: SY='V';  M= -33, -41, -81, -64,   8, -80, -20,  59, -60,  10,  -3, -58, -71, -47, -60, -43,   2,  61, -47, -36;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='K';  M= -11, -75,   0,  -3, -74, -57,  15, -46,  68, -34, -38,   5, -50,  18,  26,   8,  14, -53, -70, -52;
/M: SY='L';  M= -22, -54, -93, -75,  12, -95, -60,  18, -71,  74,  33, -71, -82, -55, -71, -57, -38,  -2, -52, -19;
/M: SY='Q';  M= -14, -35, -21,  30, -72, -31, -20, -60,   4, -37,  -7,  -1, -52, 102, -17, -17, -20, -50, -69, -52;
/M: SY='I';  M= -48,   3,-104, -88, -38,-103, -74,  80, -84,  47,  -4, -81, -90, -69, -83, -66, -41,  22, -66, -57;
/M:
/M:
/M: SY='T';  M= -21, -48, -50, -38, -56, -55, -43,   9, -36, -44, -28, -36, -57, -29, -43,   2,  99, -23, -66, -53;
/M: SY='A';  M=  86, -49, -38, -32, -75, -30, -44, -62, -37, -66, -46, -30, -52,   0, -45,  16, -19, -47, -79, -66;
/M:
/M: SY='Q';  M= -30, -75,  -2,   1, -73, -60,  -1, -61,  -5, -48,  -3, -14, -53, 111, -17, -10, -12, -52, -70, -53;
/M: SY='E';  M= -42, -96,  13, 100, -96, -30, -29, -87, -12, -84, -64,  -8, -56, -10, -38, -28, -37, -75, -93, -71;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='R';  M= -49, -88, -45, -10, -94, -73, -22, -78,  43, -72, -52, -27, -64,  -1,  99, -24, -38, -70, -75, -66;
/M: SY='F';  M= -79, -78,-102, -98, 106,-108, -17, -54, -92, -41, -40, -69, -96, -66, -85, -73, -71, -56,   5,  85;
/M: SY='R';  M= -18, -11,  -8,   3, -70, -18,  30, -59,  12, -58, -36,  15, -50,  26,  75, -16,  -8, -49,   2, -50;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='S';  M=  25,  13, -36, -20, -61, -53,  -1, -47, -21, -51, -30,   8, -29, -13, -32,  71,  35, -38, -65, -51; D=-12;
/I:         I=-12; DM=-64;
/M: SY='M';  M= -37, -46, -87, -69, -31, -87, -54,  62, -65,  44,  64, -22, -77, -51, -66, -49, -30,  29, -51, -42;
/M: SY='T';  M=  23,   1, -35,  -7, -19, -36,  -6, -15, -18, -37, -18,  15, -55, -10, -19,  -3,  71,  -5, -53, -40;
/M: SY='R';  M= -17, -73, -20,   2, -71, -57,  17, -38,  21, -39, -36,   9,  29,  30,  44,  30,  18, -28, -68, -51;
/M: SY='S';  M=  22, -52, -34, -17, -46, -49,   7,  -5, -17, -14,  42,  -1, -33,  11, -28,  51,  14,  -1, -52, -38;
/M: SY='Y';  M= -65, -71, -85, -75,  53, -97,   3, -51, -71, -30, -37, -17, -87, -52, -70, -60, -57, -50,   2, 120;
/M: SY='Y';  M= -60, -66, -88, -77,  44, -95, -19, -28, -72, -26, -30, -60, -85, -53, -71, -27, -52, -42,  30, 120;
/M: SY='R';  M= -45, -85, -42, -22, -89, -71,  -2, -74,  25, -69, -49, -26, -63,  12, 100, -17, -18, -65, -73, -63;
/M: SY='G';  M= -26, -20,  24,   5, -73,  51, -19, -62,   7, -60, -37,  38, -50,   2,   8,  14,  -6, -51, -70, -24;
/M: SY='A';  M=  80, -12, -55, -42, -63, -47, -45, -44, -41, -34, -34, -35, -52, -32, -48,  33,  -9, -14, -70, -59;
/M: SY='H';  M=   2, -25,  35,   4, -69, -57,  62, -27,   6, -31,  11,  21, -50,  44, -19,   8,  -9,  -5, -67, -49;
/M: SY='G';  M=  45,  23, -47, -31, -50,  61, -35, -13, -31, -40, -22, -31, -55, -22, -39, -18, -17, -17, -58, -16;
/M: SY='C';  M=  49,  50, -71, -53,   8, -39, -39,  34, -49,  -7,  -3, -47, -64, -37, -51, -33, -10,  33, -41, -31;
/M: SY='I';  M= -51, -55,-108, -91,   3,-106, -74,  65, -87,  49,  33, -85, -91, -69, -85, -69, -44,  42, -62, -55;
/M: SY='L';  M= -45,  -6,-102, -84,  -8, -99, -67,  53, -80,  57,  10, -77, -86, -65, -79, -62, -38,  45, -59, -51;
/M: SY='V';  M= -15,  36, -83, -65, -16, -82, -51,   9, -62,  -1,  38, -59, -73, -49, -63, -44,  -3,  79, -50, -40;
/M: SY='Y';  M= -82, -80,-102, -98,  76,-109, -16, -57, -93, -44, -43, -69, -97, -66, -86, -74, -74, -59,   6, 118;
/M: SY='D';  M= -43, -98, 108,   4,-100, -52, -33, -95, -31, -92, -73,  15, -57, -14, -51,  -6, -40, -80, -99, -75;
/M: SY='I';  M= -27,   0, -99, -82, -43, -97, -69,  71, -79,  15,   2, -76, -86, -66, -80, -60, -18,  63, -65, -54;
/M: SY='T';  M=  -3, -13, -26, -30, -66, -48, -39, -52, -31, -57, -36,  -7, -52, -23, -41,  24,  96, -40, -71, -58;
/M: SY='N';  M= -18,   3,  47,  -1, -78, -57, -19, -68,  25, -65, -41,  64, -50,  18,  25,  25, -19, -56, -73, -54;
/M: SY='R';  M=  -9, -77, -19,  44, -76, -57,  -2, -45,  28, -52, -39, -11,  -6,  45,  47,  20, -19, -34, -71, -53;
/M: SY='E';  M=  -5, -77,  23,  44, -76, -27,   0, -51,  21, -41, -39,  23, -49,  28,   7,  28,   5, -54,   8, -52;
/M: SY='S';  M= -14, -46, -45, -39, -79, -43, -48, -64, -41, -70, -50, -33, -51, -33, -49,  88,  60, -47, -83, -70;
/M: SY='F';  M= -69, -71,-100, -91, 109,-104, -20, -44, -85,  -6, -30, -67, -92, -62, -80, -67, -61, -46,  25,  57;
/M: SY='E';  M= -12, -77,  42,  50, -77, -42,  19, -67,   6, -17, -40,  22, -49,  27,  -1,   8,  -7, -44, -72,  -8;
/M: SY='N';  M=  13, -38,  13,   9, -74, -22,  40, -43,  22, -61, -38,  63, -49,   3,   9,   2,  -1, -39, -70, -26;
/M: SY='V';  M=  12,  -6, -74, -57, -33, -76, -45,  25, -53,  35,   9, -52, -68, -41, -55, -24,   9,  56, -46, -36;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='K';  M= -17, -78,  10,  19, -77, -38,   0, -67,  47, -48, -18,  20,   5,  33,  30,  13,   3, -55, -72, -22;
/M: SY='N';  M=  -6, -72,   4,  10,  -9, -31,  28, -39,  25, -11, -35,  32, -49,  26,  25,  18, -11, -49, -68,   4;
/M:
/M: SY='M';  M= -17, -39, -58, -41, -21, -67, -33,  34,   2,  36,  38, -39, -59, -27,  10, -19, -17,  30, -40,  -7;
/M: SY='E';  M= -26, -80,  32,  45, -80, -32,   8, -70,  39, -51, -42,  26, -49,  35,  -4,  10,  16, -58, -74, -54;
/M: SY='E';  M= -27, -21,  59,  70, -79, -57,  -1, -69,   8, -66,  -3, -10, -51,  31, -19, -15,  -5, -57, -74, -55;
/M: SY='I';  M=   3,  14, -90, -72,  17, -85, -53,  56, -67,  41,  -2, -63, -75, -53, -66, -47, -27,  37, -49, -39;
/M: SY='R';  M= -25, -77,  30,  23, -77, -56,  14, -30,  37, -28, -40,  19, -49,  39,  43, -14,  -4, -36, -72, -29;
/M: SY='Q';  M=   8, -76,   6,  37, -75, -56,  -1, -41,  36, -41, -17,   9, -49,  42,  12,  17,  -4, -42, -71,  -8;
/M: SY='Y';  M= -10, -14, -26,  16, -25, -59,  49, -43,  30,  -8,  24,  32, -52,   6, -23,  -4, -17, -36, -58,  54;
/M: SY='A';  M=  44,  10, -41,  -6,  -8,   0, -28,  -7, -24,  -7, -12,  -9, -55, -15, -21,   6,  18,  13, -47, -35;
/I:         I=-10; MI=0; MD=-52; IM=0; DM=-52;
/M: SY='Q';  M= -17, -74,  11,  17, -72,   9,  13, -62,  -3, -49, -37,  25,  22,  39,  -3,  19,   2, -24, -10, -25; D=-10;
/I:         I=-10; MI=0; MD=-52; IM=0; DM=-52;
/M: SY='E';  M= -12, -32,  23,  48, -48, -28,   0, -41,  12, -48, -39,   3,  38,  26,  -8,  22,  -7, -53, -71, -52;
/M: SY='N';  M= -20, -80,  49,  20, -79,   4, -19, -70,   5, -48, -43,  59,  -1,  14, -11,   9,   9, -57, -74, -55;
/I:         I=-7; MI=0; MD=-36; IM=0; DM=-36;
/M: SY='V';  M=  -1,  14, -79, -61,   3, -74, -41,  51, -56,  11,  19, -52, -37, -42, -55, -36, -12,  53, -39,  13;
/M: SY='P';  M= -12,   7, -26,  -8, -40, -49, -28,  26, -24, -16, -12, -28,  59,  18, -34, -14,  -1,  34, -48, -12;
/M: SY='I';  M= -16,  -9, -59, -41,   7, -68, -33,  52,   7,   3,  42, -13, -60, -27,   8, -29,  13,  22, -40, -29;
/M: SY='M';  M=   4,   5, -77, -58,  -3, -58, -12,  48, -53,  19,  55, -50, -63, -39, -52, -33, -18,  39, -37,  11;
/M: SY='L';  M= -58, -62,-112, -94, -29,-113, -81,  46, -91,  74,  30, -91, -96, -72, -89, -77, -51,  19, -65, -61;
/M: SY='V';  M=  -1,   7, -95, -78, -41, -93, -64,  49, -74,  31,  -9, -71, -83, -61, -75, -56, -33,  69, -61, -51;
/M: SY='G';  M=  32, -50, -33, -30, -81,  81, -45, -69, -38, -73, -52, -28, -51,  -6, -47,   1, -19, -52, -84, -71;
/M: SY='N';  M= -29, -70, -12,  -9, -80, -53,  -9, -71, -19, -71, -51, 108, -54, -12, -32,   9,   4, -59, -80, -62;
/M:
/M: SY='C';  M=   9,  67, -61, -43, -11, -69, -34,  36, -13,  -3,  23, -14, -61, -29, -44,  30,  -1,  17, -40, -29;
/M:
/I:         I=-6; MD=-33;
/M: SY='L';  M= -20,  26, -32, -30, -30, -70, -35,   2, -40,  63,  31, -41, -61, -10, -44, -22, -18,  -2, -42, -31; D=-6;
/I:         I=-6; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='E';  M=   1, -68,  17,  37, -67, -21, -16, -57,  15, -22, -34,   8, -17,  22,   8,  12,  -4, -14,  -9, -47; D=-6;
/I:         I=-6; DM=-33;
/M: SY='E';  M=  -6, -26,  29,  43, -32, -56,  -6, -65,  17, -45, -20,  21,  -4,  31,   0,  13,  22, -44, -71, -52;
/M: SY='N';  M=  -9, -77,  21,  28, -77, -56, -18, -46,  26, -35, -40,  43,  10,  39,  13,   6,   1, -31, -72, -29;
/I:         I=-10; MD=-52;
/M: SY='R';  M= -17, -73, -26,  -8, -71, -33, -20, -44,  31, -58, -14,  14, -25,   1,  84,  -9, -21, -49,  -3, -52; D=-10;
/I:         I=-10; MI=0; MD=-52; IM=0; DM=-52;
/M: SY='Q';  M=  11,   9, -16,  34, -61, -58,  -3, -37,   8, -39, -29, -15, -51,  56,   6,   1,  -8,  23, -62,  -3;
/M: SY='V';  M= -41, -49, -86, -69, -41, -91, -61,  33, -64,  -7,   7, -66, -81, -23, -68, -53, -16,  88, -62, -52;
/M: SY='S';  M= -17, -72,  27,   2, -35, -44, -19, -59,  19, -46,   7,  14,  25,  12, -18,  45,  35, -49, -68, -50;
/M: SY='T';  M=  -3, -68, -22,  31,  11, -57,  -3, -53,   4, -53, -32,  -1,  -1,  23,  21,  18,  48, -30, -64, -29;
/M: SY='E';  M= -25, -77,  26,  65, -47, -56,   1, -49,  21, -51, -40,  23, -28,  22,  -1,  11,  -9, -55, -11, -53;
/M: SY='E';  M=  -3, -77,  36,  60, -76, -58,  -4, -25,  -3, -41, -12,   1, -50,  52,  -4,  -9,  -9, -21, -72, -30;
/M: SY='A';  M=  58, -14, -50, -33, -41,  28, -34,  13, -32, -22,   6, -34, -59, -23, -40, -25, -19,  19, -51, -39;
/M: SY='Q';  M=  -3,  -9,   8,  31, -75, -56,   1, -41,  45, -29, -39,  23, -49,  52,  20, -14, -18, -38, -71, -33;
/M: SY='Q';  M=   1, -77,  -1,  42, -76, -40,  -4, -66,  38, -39,   1,   4, -49,  45,  22,  11,   6, -54, -71, -53;
/M: SY='F';  M= -28, -38, -75, -57,  66, -74, -34, -13, -36,  26,  18, -28, -65, -39, -52, -35, -11,   3,  54,  63;
/M: SY='C';  M=  74,  76, -62, -50, -59, -24, -48, -25, -48, -50, -31, -39, -52, -37, -53,  16, -15, -32, -67, -56;
/M: SY='E';  M=  -9, -79,  40,  50, -79, -45, -18, -69,  41, -66,  -7, -10, -49,  36,  16,   6,  -7, -57, -73, -54;
/M: SY='E';  M= -14, -81,  31,  53, -81, -55, -18, -71,  26, -67, -43,  26, -49,  35,  16,  25,  -5, -59, -75, -55;
/M: SY='N';  M= -24, -23, -33,  -8, -46, -61,  43,   7,  14,  19,   9,  58, -53,   7, -27, -20, -17, -18,  -3,  22;
/I:         I=-12; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='N';  M= -20, -12,  22,   8, -77,  42,  10, -66,  29, -63, -40,  50, -50,   9,  -1,  -2, -11, -54, -72, -29;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='M';  M=  19,  -6, -65, -47, -15, -68, -35,  33, -44,  25,  64,  -4, -60, -32, -46, -11,  10,  15, -38, -12;
/M: SY='P';  M= -11, -23,  -4,   7, -37, -20,  -3, -21,  19,  12,  16,  -7,  39,  25,  -3,   3,   5, -39, -61, -29;
/M: SY='F';  M= -24, -11, -81, -64,  84, -78,  -6,   0, -59,   1,  -7, -53, -69, -43, -58, -40, -26,  -8,  47,  68;
/M: SY='F';  M= -24,  13, -74, -56,  63, -46,   4,  30, -35,   6,  45, -48, -61, -37, -33, -31,  -2,  10,  13,  22;
/M: SY='E';  M= -10, -75,  -4,  91, -37, -58, -21, -60,  -8, -49, -38, -13, -52,  -1,  -9, -18, -21, -50, -70,  -4;
/M: SY='T';  M=  17,   6, -60, -44, -47, -62, -43,   0, -42, -33, -18, -41, -60, -33, -49, -25,  87,  28, -58, -46;
/M:
/M: SY='A';  M=  82, -44, -51, -42, -73, -44, -48, -57, -43, -64, -43, -34, -15, -33, -50,  35, -16, -14, -78, -67;
/M: SY='K';  M=   1, -28, -30, -12, -31, -62, -23, -45,  81,   3, -27, -19, -54,  -4,  -4, -11, -20, -38, -61, -23;
/I:         I=-12; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='T';  M= -25, -12,  40,  44, -75, -56,   8, -64,  -4, -35, -39,  31, -49,  18, -18,   9,  50, -53, -71, -52;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='N';  M=   4, -76,  27,  -1, -77,  35, -21, -66,   1, -64, -42,  51, -50,   0, -23,  42, -21, -55, -74, -27;
/M: SY='E';  M= -25, -63,  11,  35, -15, -58,   1,  24,   4,  -8, -27,   0, -51,  23, -12,  14,  22, -14, -60,  -8;
/M: SY='N';  M= -31, -77,  -8,  -4, -81,  13,   8, -71, -15, -70, -48, 101, -54,   5, -28,  -3, -12, -59, -79, -61;
/M: SY='V';  M= -51, -55,-110, -96, -50,-110, -90,  64, -93, -16, -15, -90, -98, -82, -95, -76, -45,  86, -82, -71;
/M: SY='E';  M= -12, -79,  35,  59, -79, -57, -18, -27,  21, -47, -41,  43, -50,  15,  -5,  -1, -12, -29, -73, -27;
/M: SY='E';  M=  -9, -39,  10,  73, -78, -42, -19, -68,  17, -28, -41,   9, -50,  40, -18,   3,  -4, -56, -73, -54;
/M: SY='A';  M=  43,  13, -59, -41, -12, -67, -34,  23, -39,  12,  17, -39, -29, -28, -43,  18,   7,  18, -40, -29;
/M: SY='F';  M= -45, -54, -91, -73, 100, -93, -54,   5, -69,   8,  44, -68, -81, -54, -69, -55, -20,   7, -46, -31;
/M: SY='E';  M= -25, -63,  -8,  34, -28, -40,  -1,  -2,   6,   9,  18,   8, -51,  31,   8, -17,  27, -14, -60, -13;
/M: SY='E';  M=  -3, -36,   2,  41, -21, -42,  20, -42,  25, -25, -34,   7, -50,   2,  14,   3,  31, -14, -66, -20;
/M: SY='L';  M= -22, -15, -89, -72, -33, -88, -56,  44, -68,  60,  32, -65, -78, -54, -68, -36, -31,  34, -53, -44;
/M: SY='A';  M=  47,  -9, -53, -36, -20, -25, -33,  19, -35,  -5,  -7, -36, -58, -24, -41,   8,  18,  32, -43, -32;
/M: SY='E';  M= -15, -40,  13,  46, -80, -57,  10, -70,  44, -66, -42,  15, -50,  22,  40,  14,  -4, -47, -74, -55;
/M: SY='K';  M= -10, -75,  23,  35, -46, -56, -18,  -8,  41, -17, -38,  12, -49,  24,  23,  -1,  -9, -24, -70, -51;
/M: SY='I';  M= -15,   9, -84, -65, -15, -79, -46,  61, -61,  35,  34, -57, -70, -46, -59, -41,  -8,  32, -43,   4;
/M: SY='M';  M= -24,   3, -54, -15,   1, -66, -31,  26,   6,  37,  39, -16,  -9,  -2, -27, -15, -17,  -5, -40,  24;
/M: SY='Q';  M=   5, -27,   9,  39, -74, -56,  -5, -63,  30, -25,  13,   8, -49,  44,  10,  22,  -9, -52, -70, -28;
/M: SY='R';  M=   3, -70, -21,   0, -67, -57,   6, -27,  33, -24, -18,  28, -29,  31,  36,   6,  17, -14, -66, -13;
/M: SY='H';  M=  -1, -27,  -4,  15, -57, -45,  28,  -2,  24, -12,  22,  17,  -9,  15,  -4,  -4,  -9,  -1,   1,   9;
/M: SY='Q';  M=  -8, -76,  15,  27, -47, -24,   0, -41,  40, -63, -14,  10,   8,  45,  -4,  10,   4, -27, -71, -29;
/M: SY='N';  M=  -7, -73,  15,  19, -40, -30, -18, -60,  22,  -9,  12,  33, -12,  27,   0,  17,  11, -36, -68, -17;
/M: SY='Q';  M= -10, -26,  10,  33, -40,   2,  25, -61,   1, -32, -17,  26,  -4,  42, -18,  13,  15, -50, -20, -31;
/M: SY='E';  M= -11, -70,  22,  25, -32, -32,   0,  -2,  23, -19, -34,   2,  23,   7,  -3,  11,   7, -15, -66, -24;
/I:         I=-3; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='N';  M=  -5, -28,   1,   6, -26,  -9,   0, -21,   4, -10, -13,   8, -20,   7,  -3,   5,  -3,  -9, -26, -19; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Q';  M=  -6, -19,  -1,  -5, -23, -34, -14, -20,  -1, -12,  -1,   9, -21,  20,   2,  17,   0, -12, -11, -30; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Q';  M=  -7, -49, -14,  -2, -32, -25,   1, -38,  13, -25, -22,   4, -12,  33,   9,  20,  -2, -22, -46, -34; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Q';  M= -11, -67,   9,  20, -66, -51,   6, -40,   7, -32, -33,  28, -21,  33,  10,  18,  -1, -21, -63, -46; D=-3;
/I:         I=-3; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='Q';  M= -16, -66,  15,  14, -38,  17, -16, -23,  12, -36,  -8,  14,  12,  28, -16,  16, -16, -24, -62, -45; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Q';  M=  -1, -50,  -9,  12, -31, -16,   0, -12,   1, -27, -23,   8,   6,  25,  10,  15,  14,  -9, -47, -35; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Q';  M= -18, -71,  19,  23, -70, -25, -16, -43,  14, -36, -36,  35,  -5,  56,   5,   4, -16, -20, -65, -29; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Q';  M= -13, -50,   5,  13, -22,  -3, -14, -27,   1, -17,  -8,  19, -12,  21,  -2,  15,  17,  -7, -47, -18; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Q';  M=  -2, -11,   5,   0,  -5,  -3,  -3,  -1,   2,  -4,   0,   3,  -8,   6,  -1,   1,   1,   0, -10,  -8; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Q';  M=  -6, -51,  -4,   7, -49,  -6,   5, -19,  12, -15, -24,  15, -36,  21,   7,  18,  15,  -9, -48, -16; D=-3;
/I:         I=-3; DM=-15;
/M: SY='L';  M=  -2,  -6,  -9,  -4,  -2,  -8,   0,   6,  -3,   6,  -1,  -4,  -9,   0,  -7,  -2,  -3,   5,  -6,  -2; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Q';  M=  -5, -55,  17,   7, -54, -11,  13, -32,  23, -22, -28,  22, -16,  23,   0,   8,   5, -22, -51,  -2;
/M: SY='L';  M=  -2,  -9,  -5,   0,  -3,  -6,   2,  -1,   1,   5,   0,  -3,  -1,   5,   1,   0,   0,  -1,  -9,  -4;
/M: SY='Q';  M=   0, -12,  -1,   3,  -7,  -7,   1, -10,   0,  -6,  -6,   4,   2,   6,  -1,   4,   5,  -2, -11,  -8;
/M: SY='Q';  M=  -1, -13,   4,   4,  -7,  -4,  -3, -11,   5,  -9,  -7,   5,   3,   6,   1,   1,   2,  -9, -12,  -9;
/M: SY='Q';  M=  -3, -13,   3,   7, -13,  -5,  -3, -11,   4,  -8,  -7,   1,  -1,   8,   0,   3,   3,  -9, -12,  -9;
/M: SY='P';  M=   0,  -4,   0,   1,  -2,   0,  -1,  -2,   1,  -3,  -2,   1,   2,   1,   0,   1,   1,  -1,  -3,  -2;
/M: SY='K';  M=   0,  -4,   0,   1,  -4,   0,   0,  -3,   2,  -3,  -2,   1,   1,   1,   0,   1,   1,  -1,  -4,  -3;
/M: SY='K';  M=  -1,  -4,  -1,   0,  -4,  -1,   0,  -2,   2,  -3,  -2,   1,   1,   2,   1,   0,   1,  -3,  -4,  -3;
/M: SY='K';  M=   0,  -1,  -1,   0,  -3,  -1,   0,  -1,   2,  -2,  -1,   1,   1,   2,   0,   0,   0,  -2,   0,  -1;
/M: SY='S';  M=  -1,  -1,   0,   1,  -2,   0,  -1,  -3,   1,  -2,  -1,   1,  -2,   2,   0,   2,   1,  -2,  -3,  -3;
/I:         I=-2; MD=-10;
/M: SY='C';  M=  -1,   3,   0,   0,  -2,  -1,  -1,  -2,   0,  -2,  -1,   1,   0,   1,   0,   1,   0,  -2,  -3,   0; D=-2;
/I:         I=-2; MD=-10;
/M: SY='Q';  M= -12, -63, -10,  15, -31, -43, -19, -33,  11, -33, -11,   0, -19,  27,  -8,   4,   9, -14, -60, -21; D=-2;
/I:         I=-2; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='C';  M=   0,   2,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,  -1,   0,   0,  -1,  -1,  -1;
/I:         I=-10; MI=0; MD=-54; IM=0; DM=-54;
/M: SY='I';  M=  -9,   3, -29, -17, -16, -24,  -2,  18, -15, -17,  -4,  -3, -37,  -9, -15,  -8,  -9, -10,  -4, -20; D=-10;
/I:         I=-10; DM=-54;
/M: SY='C';  M= -22,  52, -27, -11, -48, -41,  15, -35,  10, -26,  -3,  11,  -7,  12, -12,  16,  -1, -15, -53, -39;
/I:         I=-10; E1=0; IE=-210; DE=-54;

» more

Post-processing [info]

COMPETES_HIT_WITH

PS51417; PS51418; PS51420; PS51421; PS51422; PS51423; PS51424

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	534 in 534 different sequences
Number of true positive hits	528 in 528 different sequences
Number of 'unknown' hits	1
Number of false positive hits	5 in 5 different sequences
Number of false negative sequences	4
Number of 'partial' sequences	1

Precision (true positives / (true positives + false positives))	99.06 %
Recall (true positives / (true positives + false negatives))	99.25 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	N_Hulo, L_Cerutti
Version [info]	5

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	528 sequences AGAP1_HUMAN (Q9UPQ3), AGAP1_MOUSE (Q8BXK8), AGAP1_XENLA (Q6NRL1), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	4 sequences CPLN2_HUMAN (Q9BU20), CPLN2_MOUSE (A2A825), CPLN2_XENLA (Q6GNL4), CPLN2_XENTR (B7ZTR0) » more
UniProtKB/Swiss-Prot 'Partial' sequences	1 sequence RAB2A_MESAU (P86207)
UniProtKB/Swiss-Prot 'Unknown' sequences	1 sequence RAB7_EPICO (H9BW96)
UniProtKB/Swiss-Prot False positive sequences	5 sequences GSP1_ENCCU (Q8SS11), HSLU_THEMA (Q9WYZ2), HSLU_THEP1 (A5IJQ2), » more
PDB [Detailed view]	257 PDB 1EK0; 1G16; 1G17; 1HUQ; 1KY2; 1KY3; 1N6H; 1N6I; 1N6K; 1N6L; 1N6N; 1N6O; » more