PROSITE entry PS51418

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51418
Entry name [info]	RAN
Accession [info]	PS51418
Entry type [info]	MATRIX
Date [info]	01-DEC-2008 CREATED; 13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51417
Associated ProRule [info]	PRU00752

Name and characterization of the entry

Description [info]

small GTPase Ran family profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=165;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=160;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-6.1701593; R2=0.0037684; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-3205.4382324; R2=12.5203867; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=3920; H_SCORE=45874; N_SCORE=8.6; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=3363; H_SCORE=38901; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-19; D=-40; I=-40; I0=-19; B1=*; E1=*; MI=-210; MD=-210; IM=-210; DM=-210;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-210; BD=-210;
/M: SY='Q';  M=  -7, -25, -10,   5, -46, -43,  -7, -33,  14, -35, -14,  29, -37,  44,  -4,   0,   2,  -4, -48, -33;
/M: SY='Q';  M=   6, -59,   2,  25, -57, -20,  -6, -45,  15, -45, -23,  14, -19,  36,  -6,  10,  -6, -31, -56, -38;
/M: SY='D';  M=   6, -67,  41,  30, -66, -42,  -7, -55,   6, -53, -30,  28, -37,  28, -10,  12,  -9, -22, -62, -43;
/M: SY='N';  M=   5, -39,  17,  22, -35, -26,  -6, -37,  17, -42, -20,  25, -37,  15,  11,  -2,  -4,  -3, -53, -33;
/M: SY='K';  M=  -2, -25, -19,  10, -35, -48, -11,  12,  15, -16,  -6,  -4,   9,   6,   7,  -6,   1,   7, -41, -19;
/M: SY='P';  M=  12, -38, -23,  -2,  -7, -47, -14,   1,  -6, -23,  -5,  -7,  44,   2, -17,  -7,  22, -11, -40, -27;
/M: SY='T';  M= -14, -54,  -8,  13, -52, -45,  -5, -34,  19, -40, -19,  -1, -39,  22,  -2,  32,  45, -31, -52, -36;
/M: SY='F';  M= -45, -52, -73, -62,  93, -81, -12,  -6, -57,  -2,  -2, -48, -71, -40, -57, -45, -38, -17,   6,  43;
/M:
/M: SY='L';  M= -27,   9, -72, -55, -20, -75, -46,  20, -51,  52,  19, -51, -65, -39, -53, -38, -20,  40, -44, -34;
/M: SY='V';  M= -34, -39, -87, -72, -30, -91, -65,  57, -68,  10,   4, -68, -79, -57, -71, -55, -28,  68, -60, -50;
/M: SY='L';  M= -42, -49, -83, -68, -13, -90, -57,  31, -60,  67,  20, -66, -77, -48, -61, -55, -35,  10, -47, -37;
/M: SY='V';  M= -30, -19, -81, -65, -30, -83, -59,  41, -61,   8,   3, -61, -74, -51, -65, -47, -25,  74, -57, -46;
/M:
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M:
/M:
/M: SY='G';  M=   6, -48,   1,  19, -65,  60, -21, -51, -12, -54, -35,  -4, -38,  -3, -23,  -4, -10, -38, -66, -51;
/M: SY='T';  M=  -2, -31, -34, -22, -45, -35, -27, -22, -21, -34, -17, -18, -38, -13, -29,  26,  68,  18, -53, -41;
/I:         I=-6; MD=-33;
/M: D=-6;
/I:         I=-6; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='K';  M= -32, -69, -23,  -8, -73, -54, -11, -60,  84, -55, -37, -12, -48,  10,  25, -22, -23, -51, -60, -49; D=-6;
/I:         I=-6; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='T';  M=   7, -36, -21, -13, -53, -34, -24, -36, -14, -43, -24, -13, -38,   7, -22,   7,  79, -25, -58, -45;
/M: SY='T';  M=   4, -34, -33, -25, -48, -37, -31, -18, -22, -22, -19, -21, -41, -17, -29,  -4,  82, -11, -58, -45;
/M: SY='F';  M= -49, -54, -76, -66,  94, -84,  -7, -20, -61,  -3,  -8, -49, -73, -42, -59, -48, -41, -24,  12,  57;
/M: SY='V';  M= -27, -35, -72, -56, -28, -77, -49,  42, -52,  12,   3, -53, -68, -42, -56, -24, -21,  68, -51, -39;
/M: SY='K';  M= -22, -65, -13,   2, -65, -50,  28, -53,  70, -50, -29,  -5, -43,  18,  12, -12,  16, -44, -57, -43;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M:
/M: SY='H';  M= -22, -50, -25, -13, -16, -54, 105,   8,  -5, -27, -15, -16, -49,  -3, -12, -17, -16, -23, -28,  -4;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='L';  M= -14, -32, -40, -22, -21, -56, -20,  25,  -1,  38,  24, -23, -48,   5, -24,  -5,  -7,   0, -32, -21;
/M: SY='T';  M= -11, -45, -12,  15, -49, -41, -16, -33,  -4, -28, -19,  -7, -40,   2, -14,  17,  68, -25, -53, -38;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M:
/I:         I=-10; MI=0; MD=-50; IM=0; DM=-50;
/M: SY='E';  M= -20, -64,   7,  76, -64, -43, -13, -49,   0, -52, -33,  11, -41,   7, -13,  -9, -14, -10, -64, -45;
/M: SY='F';  M= -41, -50, -66, -56,  93, -76,  -7, -23, -52, -18, -12, -42, -67, -35, -52, -21, -34, -23,  10,  56;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='E';  M=  -1,  -3,   0,   3,  -3,  -2,   0,  -1,   0,  -2,  -1,   1,  -2,   1,   1,   0,   0,  -2,  -3,  -2; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='K';  M= -18, -59, -15,   3, -57, -49,  13, -45,  62, -25, -23,   9, -29,  14,  17,  -8, -10, -12, -54, -39; D=-1;
/I:         I=-1; DM=-4;
/M: SY='K';  M= -19, -69,  13,   8, -70, -47,  -6, -59,  48, -54, -32,  11, -40,  43,  43,  -7, -11, -47, -61, -44; D=-1;
/I:         I=-1; DM=-4;
/M: SY='Y';  M= -30, -50, -35, -25,  14, -62,  30, -31, -20, -29, -17, -24, -56, -14, -26, -25,  -5, -27,  -2, 100; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='I';  M= -13, -37, -26,  16, -30, -52, -15,  32,   5,  -3,  -1,   9, -44,   0, -17, -11,  -5,  24, -37, -24; D=-1;
/I:         I=-1; DM=-4;
/M: SY='A';  M=  60, -32, -27, -20, -61, -29, -30, -47, -23, -51, -31, -16,  45, -14, -32,  19,  -2, -31, -64, -52; D=-1;
/I:         I=-1; DM=-4;
/M: SY='T';  M= -10, -37, -36, -33, -56, -37, -39, -33, -32, -44, -32, -27, -43, -27, -37,  -8,  95, -24, -64, -52; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='M';  M= -19,  20, -66, -47, -15, -67, -33,  35, -43,  39,  40, -42, -57,  -7, -44, -28, -12,  28, -32, -22; D=-1;
/I:         I=-1; DM=-4;
/M: SY='G';  M= -26, -50, -37, -40, -79,  92, -51, -77, -51, -79, -64, -37, -49, -42, -54, -23, -30, -60, -70, -71; D=-1;
/I:         I=-1; DM=-4;
/M: SY='V';  M=   3,   6, -28, -21, -13, -26, -19,  11, -20,  -5,  -1, -19, -24, -16, -22, -11,  -6,  29, -21, -16; D=-1;
/I:         I=-1; DM=-4;
/M: SY='E';  M=  -5, -74,  35,  64, -73, -42,  -9, -63,   3, -60, -37,  16, -39,  12,   9,  -2, -13, -51, -68, -48; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='V';  M= -33, -40, -83, -69, -33, -85, -64,  44, -65,   0,   1, -65, -77, -56, -68, -51, -28,  78, -62, -50; D=-1;
/I:         I=-1; DM=-4;
/M: SY='H';  M= -17, -54, -14,   2, -38, -49,  82, -37,   6, -38, -18,  15, -42,   9,  17,   1,  -9, -30, -43,  34; D=-1;
/I:         I=-1; DM=-4;
/M: SY='P';  M= -14, -55,  -8,  10, -15, -46,  23, -39,   5, -40, -19,   9,  62,  40,  -7,  -6,  -7, -31, -51, -34; D=-1;
/I:         I=-1; DM=-4;
/M: SY='L';  M= -44, -50, -90, -73, -13, -96, -62,  36, -68,  67,  41, -71, -80, -52, -68, -60, -36,   9, -49, -43; D=-1;
/I:         I=-1; DM=-4;
/M: SY='D';  M= -13, -59,  31,  14, -56, -41,  -7, -36,  21,  -7, -21,  26,  -5,  14,  -7,   6,   6, -12, -55, -37; D=-1;
/I:         I=-1; DM=-4;
/M: SY='F';  M= -47, -55, -77, -68,  97, -83, -20,  -9, -63,   9,   0, -54, -74, -46, -62, -50, -42, -15,  -2,  28; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='H';  M=   0,   0,   0,   0,   0,  -1,   1,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='T';  M=   0,   0,   0,   0,  -1,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   0,   1,   0,  -1,  -1; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='N';  M=  -1,  -2,   0,   0,  -3,  -2,  -1,  -3,   0,  -3,  -2,   4,  -2,   0,  -1,   1,   0,  -2,  -3,  -2; D=-1;
/I:         I=-1; DM=-4;
/M: SY='R';  M=  -1,   2,  -1,   0,   0,  -1,  -1,  -1,   1,  -1,   0,  -1,  -2,   0,   2,   0,   0,  -1,  -2,   0; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='G';  M= -14, -45, -19, -15, -65,  73, -28, -56, -15, -58, -40, -17, -42, -12,  10, -10, -15, -43, -63, -52; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='K';  M= -14, -62,  -8,  27, -60, -46,  -7, -48,  41, -44, -24,   1,  29,  31,   7,  -1,  -3,  -3, -57, -39; D=-1;
/I:         I=-1; DM=-4;
/M: SY='I';  M= -23, -32, -72, -54,   8, -72, -39,  61, -50,  20,  13, -48, -62, -36, -51, -34,  -7,  35, -36,   4; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='R';  M= -13,  12, -19,  13, -40, -49,  -1,   0,   9, -13,  -9,  -8, -41,  20,  49,  -7,  -5,  -4, -44, -29; D=-1;
/I:         I=-1; DM=-4;
/M: SY='F';  M= -42, -50, -80, -66,  90, -86, -31,   3, -61,  24,  30, -57, -74, -44, -60, -50, -35,  -5, -15,  10; D=-1;
/I:         I=-1; DM=-4;
/M: SY='N';  M= -15, -43,  34,  21, -62, -22,   2, -51,   6, -49, -27,  59, -38,  14,  -9,  -4,  -8, -40, -59,  23; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='V';  M= -24,  61, -78, -62, -30, -73, -51,  37, -58,  -6,   1, -55, -67, -47, -60, -37, -19,  69, -51, -39; D=-1;
/I:         I=-1; DM=-4;
/M: SY='W';  M= -44, -57, -55, -45,  20, -71,  33, -39, -31, -33, -25, -37, -65, -27, -33, -39, -37, -37, 146,  35; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='D';  M= -39, -79, 104,   5, -83, -44, -29, -80, -29, -79, -65,  -5, -48, -12, -46, -26, -36, -68, -77, -63; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='T';  M= -10, -38, -37, -33, -57, -37, -40, -33, -33, -45, -33, -27, -44, -27, -37,  -8,  96, -24, -64, -53; D=-1;
/I:         I=-1; DM=-4;
/M: SY='A';  M=  82, -34, -39, -37, -61, -33, -44, -38, -40, -50, -37, -28, -42, -32, -44,  -5, -10, -26, -68, -58; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='G';  M= -20, -51, -13,  -3, -74,  83, -36, -65, -29, -68, -51, -18, -45, -21, -37, -14, -21, -51, -71, -62; D=-1;
/I:         I=-1; DM=-4;
/M: SY='Q';  M= -22, -63, -10,   1, -52, -49,  25, -49,  10, -47, -28,  -6, -44,  96,   1, -13, -15, -23, -53, -34; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='E';  M= -36, -76,   6,  94, -78, -46, -25, -69, -17, -69, -54,  -7, -48,  -8, -29, -24, -32, -60, -72, -59; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='K';  M=   0,  -1,   0,   0,  -1,  -1,   0,   0,   1,   0,   0,   0,  -1,   0,   0,   0,   0,   0,  -1,   0; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='F';  M= -26, -39, -54, -38,  83, -67, -16,  -9,  -4,  10,   2, -34, -58, -23, -37, -28, -18,  -9, -10,  26; D=-1;
/I:         I=-1; DM=-4;
/M: SY='G';  M= -11, -50,  21,   2, -72,  66, -23, -62, -18, -63, -42,  -4, -39,  -5, -31,  22, -12, -46, -73, -56; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='G';  M= -10, -39, -29, -22, -50,  74, -30, -35, -22, -41,  27, -20, -43, -16, -29,  -7, -10, -26, -58, -44; D=-1;
/I:         I=-1; DM=-4;
/M: SY='L';  M= -48, -57, -77, -68, -18, -82, -57,   3, -60,  79,  10, -66, -75, -51, -60, -57, -43,  -6, -48, -36; D=-1;
/I:         I=-1; DM=-4;
/M: SY='R';  M= -29, -70, -25,  -6, -73, -55,  -9, -59,  32, -54, -34, -11, -48,  26,  83,   4, -20, -50, -60, -49; D=-1;
/I:         I=-1; DM=-4;
/M: SY='D';  M= -34, -92,  97,  33, -91, -40, -19, -83, -18, -80, -62,   6, -44,   0, -39, -18, -30, -70, -88, -63; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='G';  M=  21, -34, -28, -28, -73,  78, -41, -59, -37, -65, -46, -21, -39, -27, -44,   0,  -8, -40, -75, -65; D=-1;
/I:         I=-1; DM=-4;
/M: D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='Y';  M= -60, -64, -77, -71,  46, -88,  -4, -39, -66, -28, -26, -50, -79, -46, -64, -54, -53, -40,  16, 118; D=-1;
/I:         I=-1; DM=-4;
/M: SY='I';  M= -38, -42, -93, -79, -34, -94, -73,  84, -76,   1,   1, -74, -83, -65, -78, -60, -32,  51, -66, -55; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='Q';  M= -15, -69,  15,  19, -68, -13,  55, -58,  13, -55, -31,  23, -38,  61,  11,  -4,  -8, -46, -63, -43; D=-1;
/I:         I=-1; MI=0; MD=-4; IM=0; DM=-4;
/M: SY='S';  M=  37, -31, -30, -24, -69,  48, -35, -57, -30, -60, -39, -18, -36, -19, -38,  51,  -2, -37, -72, -60; D=-1;
/I:         I=-1; DM=-4;
/M: SY='Q';  M= -20, -75,  43,  14, -74, -44,  21, -65,  12, -61, -38,  26, -40,  82, -11,  -7, -14, -52, -69, -49; D=-1;
/I:         I=-1; DM=-4;
/M: SY='C';  M=  36, 120, -63, -56, -54, -34, -49, -25, -51, -42, -27, -35, -42, -41, -52,  -2,  -6, -15, -64, -54;
/M: SY='A';  M=  77,  26, -52, -43, -60,   7, -43, -43, -41, -52, -32, -27, -38, -30, -46,   3,  -3, -28, -67, -57;
/I:         I=-8; MI=0; MD=-41; IM=0; DM=-41;
/M: SY='I';  M= -42, -46, -95, -79, -23, -98, -68,  85, -74,  25,  38, -75, -83, -60, -74, -62, -35,  22, -57, -49;
/M: SY='I';  M= -41, -45, -96, -80, -27, -98, -71,  86, -76,  18,  24, -76, -84, -62, -77, -63, -34,  33, -61, -52;
/M: SY='M';  M= -43, -50, -86, -69,  38, -90, -49,   6, -65,  26, 117, -65, -76, -48, -64, -53, -35,  -4, -36, -21;
/M:
/M:
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='V';  M= -29, -40, -76, -63, -38, -76, -59,  24, -58,   2,  -5, -58, -71, -50, -62, -42,   2,  85, -62, -50;
/M: SY='T';  M=  -3, -34, -35, -29, -64, -32, -37, -48, -31, -56, -36, -22, -40, -23, -38,  38,  92, -33, -69, -57;
/M: SY='S';  M=  21, -49, -15,  -1, -14, -45, -14, -37,  12, -40, -19,  14, -41,   4, -15,  66,  -7, -28, -53, -37;
/M: SY='R';  M= -10, -70, -33, -13, -76, -58, -12, -60,  33, -57, -38, -16, -51,   8,  93, -23, -24, -52, -62, -52;
/M: SY='V';  M= -13, -30, -29, -24, -21, -56,   4,  37, -22,   9,  21,  12, -48, -12, -28,  -1,   6,  42, -31, -19;
/I:         I=-7; MI=0; MD=-38; IM=0; DM=-38;
/M: SY='T';  M= -11, -37, -41, -30, -46, -44, -34,   5, -27, -31, -18, -27, -47, -21, -33,  -5,  92,  -9, -57, -43;
/M: SY='Y';  M= -66, -67, -83, -78,  46, -93,  -6, -43, -72, -32, -31, -54, -83, -50, -69, -58, -58, -45,  15, 123;
/M: SY='K';  M= -21, -62, -19,  -2, -61, -52, -11, -46,  81, -47,   2,  13, -45,  10,   5, -12, -14, -11, -57, -42;
/M:
/M: SY='V';  M= -28, -42, -91, -77, -39, -91, -72,  46, -74,  -6,  -4, -72, -82, -64, -76, -57, -31,  86, -69, -57;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='P';  M=  -2, -67,  16,  22, -69, -43, -15, -58,  -6, -58, -37,  20,  88,   4, -21, -10, -16, -47, -69, -50;
/M: SY='N';  M= -15, -62,  -9,   7, -61, -47,   7, -49,  14, -48, -25,  67, -40,  23,  25,  17,  24, -18, -58, -41;
/M:
/M: SY='H';  M= -38, -58, -44, -30,  15, -70, 111, -39, -24, -12, -23, -29, -62, -17, -30, -31, -30, -35,  -1,  70;
/M: SY='R';  M= -37, -75, -35, -14, -79, -61,   6, -65,  35, -59, -40, -17, -53,  10,  95, -19, -27, -57, -62, -52;
/M: SY='D';  M= -32, -82, 101,  10, -82, -44, -21, -76, -14, -74, -55,   0, -47,  -2,   4, -19, -28, -64, -79, -59;
/M: SY='L';  M= -46, -50, -98, -82, -19,-101, -69,  39, -77,  70,  16, -78, -85, -60, -76, -65, -39,  31, -55, -49;
/M: SY='V';  M=  -8,  37, -47, -23,   4, -57, -22,   9, -26, -10,  14, -27, -48,  12, -15,  -1,  25,  49, -29, -18;
/M: SY='R';  M=  -1, -57, -25, -11, -69, -10, -17, -56,   9, -55, -35, -14, -46,   2,  90, -13, -16, -45, -63, -51;
/I:         I=-5; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='V';  M= -24, -35, -60, -11, -29, -70, -40,  35, -41,  -8,  19, -43, -62, -32, -46, -33, -10,  73, -46, -35; D=-5;
/I:         I=-5; DM=-25;
/M: SY='C';  M= -17, 129, -45,  -1, -48, -47, -39, -25, -33, -38, -24, -33, -50, -28, -37, -17, -17, -19, -56, -45; D=-5;
/I:         I=-5; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='E';  M= -16, -68,  14,  63, -23,   1,  -8, -56,  32, -54, -30,   2, -18,  14,  -8,  -4,   2, -45, -63, -43;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='N';  M= -20, -72,  27,  12, -72, -34,  37, -62,   1, -59, -36,  84,  -3,  10, -15,  -1,  -5, -50, -68, -48;
/I:         I=-4; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='I';  M= -43, -46, -98, -83, -30,-100, -74,  89, -79,  21,   5, -79, -87, -66, -80, -66, -36,  35, -64, -54;
/I:         I=-12; MI=0; MD=-64; IM=0; DM=-64;
/M: SY='P';  M=   8, -42, -30, -29, -69, -37, -41, -54, -34, -60, -44, -25, 108, -27, -40,  -8, -14, -40, -73, -62;
/M: SY='I';  M= -42, -47, -93, -79, -27, -96, -69,  91, -73,   9,  34, -74, -84, -61, -74, -61, -36,  24, -60, -50;
/M: SY='V';  M=  -7, -39, -72, -64, -44, -66, -62,  20, -61, -16, -12, -55, -67, -52, -63, -34, -24,  88, -67, -55;
/M: SY='L';  M= -51, -55,-101, -83, -15,-105, -70,  34, -78,  76,  34, -81, -86, -60, -76, -69, -43,   4, -53, -48;
/M: SY='C';  M= -12, 112, -69, -56, -38, -50, -46,   5, -51, -20,  -9, -42, -52, -40, -52, -16,  13,  42, -53, -42;
/M:
/M:
/M:
/M: SY='V';  M= -23,  25, -72, -55, -22, -72, -40,  25, -50,   6,   6, -49, -63, -38, -52, -34, -16,  76, -39,   4;
/M:
/M: SY='I';  M= -24,  31, -79, -61, -24, -75, -44,  60, -57,   4,  26, -53, -65, -43, -56, -20, -17,  59, -41, -31;
/I:         I=-11; MI=0; MD=-58; IM=0; DM=-58;
/M: SY='K';  M=   0,  -1,   0,   0,  -1,  -1,   0,   0,   1,   0,   0,   0,   0,   0,   0,   0,   0,   0,  -1,   0;
/M: SY='D';  M=   0,  -1,   1,   0,  -1,   0,   0,  -1,   0,  -1,  -1,   1,   0,   0,   0,   0,   0,  -1,  -1,  -1;
/M: SY='R';  M=   0,   0,   0,   0,  -1,  -1,   0,  -1,   0,  -1,   0,   0,  -1,   0,   1,   0,   0,  -1,  -1,  -1;
/I:         I=-5; MI=0; MD=-27; IM=0; DM=-27;
/M: SY='K';  M= -27, -69, -12,  13, -73, -49,  -9, -60,  72, -55, -36,  -7, -43,  50,  12, -16, -19, -51, -59, -47;
/I:         I=-3; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='V';  M= -18, -34, -13, -31, -29, -59, -30,  29, -30, -15,  -2, -31, -53, -21, -37,  -1, -12,  70, -42, -30; D=-3;
/I:         I=-3; DM=-15;
/M: SY='K';  M= -25, -65, -23,  10, -65, -54,  -9, -52,  79, -49, -29,  -9, -45,  11,  25, -15, -16, -44,  30, -43; D=-3;
/I:         I=-3; DM=-15;
/M: SY='A';  M=  48, -57,  -7,  26, -56, -45, -10, -44,  15, -44, -23,  -2,   5,  16, -10,   8,  12, -35, -55, -39; D=-3;
/I:         I=-3; DM=-15;
/M: SY='K';  M= -23, -70, -15,  14, -72, -43,  -8, -59,  68, -55, -33,  -5, -43,  42,  33,  -7,   6, -49, -61, -46; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Q';  M= -11,   7, -15,   1,  -8, -39,   9, -30,   1, -32,  10,   9, -40,  53,   3,  26,  32, -23, -46, -31; D=-3;
/I:         I=-3; DM=-15;
/M: SY='I';  M= -32, -38, -84, -69, -34, -84, -61,  77, -65,  -3,  -2, -63, -75, -55, -67, -30, -26,  56, -58, -47; D=-3;
/I:         I=-3; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='T';  M=   0, -52,   2,   4, -49, -46, -10, -36,  14, -38, -17,  14, -39,  28, -10,   3,  54,  16, -50, -35; D=-3;
/I:         I=-3; DM=-15;
/M: SY='F';  M= -37, -49, -61, -48,  97, -73, -12, -22, -41, -17, -10, -40, -65, -30,  -3, -37, -30, -22,   1,  39; D=-3;
/I:         I=-3; DM=-15;
/M: SY='H';  M= -17, -58,  10,   5, -49, -47, 101, -43,   4, -43, -23,  -3, -41,   9,   7,   8, -10, -35, -51,   5; D=-3;
/I:         I=-3; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='R';  M=  -4, -10,  -5,  -1,  -9,  -9,   4,  -8,   3,  -3,  -5,  -2,  -8,   1,  14,  -1,  -3,  -7,  -9,  -6; D=-3;
/I:         I=-3; DM=-15;
/M: SY='K';  M=  -5, -11,  -3,  -1, -12,  -9,  -2, -10,  14,  -9,  -6,  -2,  -8,   3,   3,   0,  -3,  -9, -10,  -8; D=-3;
/I:         I=-3; DM=-15;
/M: SY='K';  M=  -1,  -3,  -1,   0,  -3,  -2,   0,  -2,   4,  -2,  -1,   0,  -2,   1,   1,   1,  -1,  -2,  -3,   0; D=-3;
/I:         I=-3; DM=-15;
/M: SY='N';  M=  -1,   0,  -1,   0,  -2,   0,  -1,   0,   0,  -2,   0,   4,  -2,   0,   0,   0,   0,  -1,  -2,  -2; D=-3;
/I:         I=-3; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='L';  M= -22,   2, -66, -49, -18, -68, -36,  33, -44,  58,  22, -44, -59, -32, -46,  -9, -15,  11, -36, -26; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Q';  M= -16, -56, -10,   4, -53, -46, -10, -42,   5, -43, -23,  -4,  -4,  90,  -6,  -3,  10, -34, -53,   3; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Y';  M= -23,  -7, -47, -31,   4, -61,  23, -16, -26, -18,  28, -28, -54, -17, -31, -23, -16, -13, -10,  99; D=-3;
/I:         I=-3; DM=-15;
/M: SY='Y';  M= -25, -36, -61, -45,  17, -68, -23,  13, -42,  -1,  29, -40, -59, -28, -44, -30, -18,  11, -16,  94; D=-3;
/I:         I=-3; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='D';  M= -29, -87,  74,  64, -86, -40, -16, -78, -11, -74, -54,   7, -10,   4, -30, -14, -24, -65, -82, -58; D=-3;
/I:         I=-3; DM=-15;
/M: SY='I';  M= -39, -43, -92, -76, -25, -94, -66,  82, -72,  14,  44, -71, -80, -58, -73, -58, -32,  33, -57, -49; D=-3;
/I:         I=-3; DM=-15;
/M: D=-3;
/I:         I=-3; DM=-15;
/M: SY='A';  M=  84, -32, -42, -39, -65, -32, -45, -39, -40, -53, -37, -27, -41, -31, -45,  -1,   8, -26, -73, -62; D=-3;
/I:         I=-3; DM=-15;
/M: SY='K';  M= -32, -71, -28,  -9, -77, -56, -11, -62,  85, -57, -38, -13, -49,  10,  33, -22,  -6, -53, -61, -51; D=-3;
/I:         I=-3; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='S';  M= -16, -60,  15,   6, -64, -43, -14, -52,  11, -52, -31,  10, -41,   7, -15,  73,  23, -41, -63, -46;
/M:
/M: SY='Y';  M= -30,   0, -60, -46,  37, -69, -12, -18, -41, -18,  -7, -37, -61, -28, -23, -31, -23, -16,  -1, 105;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='N';  M= -26, -71,   8,   7, -71, -44, -17, -65,   4, -64, -44,  99, -45,  16, -13, -15, -22, -54, -70, -50;
/I:         I=-10; MI=0; MD=-54; IM=0; DM=-54;
/M: SY='F';  M= -26, -36, -65, -48,  83, -69, -19,   7, -44,  -6,   4, -40, -35, -30, -45, -30, -18,  10, -10,  50;
/M: SY='E';  M= -12, -73,  13,  88, -77, -42, -18, -64,  -8, -65, -46,   1, -44,   2, -22,  -6, -21, -53, -75, -55;
/M: SY='K';  M= -20, -60, -19,   4, -57, -52,  -9, -43,  73,  -6,   1,  -7, -44,  11,  10,   2, -12, -35, -54, -40;
/M:
/M: SY='F';  M= -37, -46, -74, -60,  94, -79, -29,  17, -56,   6,   7, -52, -70, -41, -56, -43, -17,  -3, -16,  11;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='L';  M= -29, -42, -63, -46, -19, -72, -39,   8, -37,  63,  11, -45, -63, -30, -14, -35, -22,  28, -42, -32;
/M: SY='W';  M=   0, -35, -42, -26,  -5, -57, -15, -12, -23, -17,   0, -25, -30, -13, -29,   2, -10,  -8, 107,  66;
/M: SY='L';  M= -46, -51, -93, -76, -15, -98, -65,  36, -71,  71,  19, -74, -82, -55, -70, -62, -38,  14, -51, -44;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M: SY='A';  M=   3,  -2,  -2,  -1,  -1,  -2,  -1,   0,  -1,   1,   1,  -1,  -2,  -1,  -1,  -1,   0,   0,  -2,  -1;
/M: SY='R';  M= -35, -72, -34, -13, -78, -59, -10, -62,  40, -57, -38, -15, -51,  11,  89, -17, -25, -54, -61, -51;
/M: SY='K';  M= -20, -61, -20,  -1, -61, -52,  -9, -25,  70, -45, -25,  -7, -44,  12,  31, -11,   8, -19, -55, -41;
/I:         I=-13; MI=0; MD=-67; IM=0; DM=-67;
/M:
/I:         I=-13; E1=0; MI=0; IE=0; DE=-67;

» more

Post-processing [info]

COMPETES_HIT_WITH

PS51417; PS51419; PS51420; PS51421; PS51422; PS51423; PS51424

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	50 in 50 different sequences
Number of true positive hits	50 in 50 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	1
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	98.04 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	N_Hulo, L_Cerutti
Version [info]	7

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

50 sequences

GSP1_CANAW  (Q9P4E9), GSP1_CANGA  (Q6FR65), GSP1_EREGS  (Q74ZA9),

GSP1_NEUCR  (Q7RVL0), GSP1_YARLI  (Q8TFK3), GSP1_YEAST  (P32835), 
GSP2_YEAST  (P32836), RAN1A_LOTJA (P54765), RAN1B_LOTJA (P54766), 
RAN1_ARATH  (P41916), RAN1_ORYSI  (A2WSI7), RAN1_ORYSJ  (Q7F7I7), 
RAN1_SOLLC  (P38546), RAN2_ARATH  (P41917), RAN2_ORYSI  (A2Y7R5), 
RAN2_ORYSJ  (Q7GD79), RAN2_SOLLC  (P38547), RAN3_ARATH  (Q8H156), 
RAN3_ORYSI  (A2YEQ6), RAN3_ORYSJ  (Q69XM7), RAN4_ARATH  (Q9FLQ3), 
RANA1_TOBAC (P41918), RANB1_TOBAC (P41919), RANL_DROME  (Q9VUN3), 
RANT_MOUSE  (Q61820), RANT_RAT(Q8K586), RAN_BOVIN   (Q3T054), 
RAN_BRUMA   (P38542), RAN_CAEEL   (O17915), RAN_CANLF   (P62825), 
RAN_CARAU   (Q7ZZX9), RAN_CHICK   (P42558), RAN_DANRE   (P79735), 
RAN_DICDI   (P33519), RAN_DROME   (Q9VZ23), RAN_GIAIN   (P38543), 
RAN_HUMAN   (P62826), RAN_MACFA   (Q4R4M9), RAN_MOUSE   (P62827), 
RAN_ONCVO   (P38544), RAN_PLAFA   (P38545), RAN_PONAB   (Q5R556), 
RAN_RAT (P62828), RAN_SALSA   (Q9YGC0), RAN_TETPY   (P41914), 
RAN_TETTH   (P41915), RAN_VICFA   (P38548), RAN_XENLA   (P52301), 
RAN_XENTR   (Q6GL85), SPI1_SCHPO  (P28748)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

1 sequence

GSP1_ENCCU  (Q8SS11)

PDB
[Detailed view]

150 PDB

1BYU; 1I2M; 1IBR; 1K5D; 1K5G; 1QBK; 1QG2; 1QG4; 1RRP; 1WA5; 2BKU; 2MMC;
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