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PROSITE entry PS51410


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51410
Entry name [info] BH4_AAA_HYDROXYL_2
Accession [info] PS51410
Entry type [info] MATRIX
Date [info] 01-FEB-2010 CREATED;
01-FEB-2010 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00316
Associated ProRule [info] PRU00743

Name and characterization of the entry

Description [info] Biopterin-dependent aromatic amino acid hydroxylase family profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=347;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=342;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.8390105; R2=0.0242308; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=8523.0000000; R2=0.0000000; TEXT='Heuristic 0.1%';
/CUT_OFF: LEVEL=0; SCORE=238; H_SCORE=8523; N_SCORE=8.6; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=152; H_SCORE=8523; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-10; D=-80; I=-80; B1=-500; E1=-500; MI=-150; MD=-150; IM=-150; DM=-150;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 44 in 44 different sequences
Number of true positive hits 41 in 41 different sequences
Number of 'unknown' hits 3 in 3 different sequences
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Version [info] 2

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
41 sequences

AAAH_CHLPN  (Q9Z6L3), PH3H_STRC4  (F5BFC8), PH4H_BOVIN  (Q2KIH7), 
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UniProtKB/Swiss-Prot
'Unknown' sequences
3 sequences

AUR42_RANAE (P69025), AUR42_RANRN (P69024), AUR43_RANAE (P82399)

		
PDB
[Detailed view]
72 PDB

1DMW; 1J8T; 1J8U; 1KW0; 1LRM; 1LTU; 1LTV; 1LTZ; 1MLW; 1MMK; 1MMT; 1PAH;
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