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PROSITE entry PS51407


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General information about the entry

Entry name [info] LAMP_3
Accession [info] PS51407
Entry type [info] MATRIX
Date [info] 01-NOV-2008 CREATED;
10-MAY-2017 DATA UPDATE;
27-MAR-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00280
Associated ProRule [info] PRU00740

Name and characterization of the entry

Description [info] Lysosome-associated membrane glycoprotein family profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=387;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=382;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6685364; R2=0.0048871; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=82462.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=2503; H_SCORE=82462; N_SCORE=14.9; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=784; H_SCORE=82462; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-19; D=-100; I=-100; B1=-350; E1=-350; MI=-105; MD=-105; IM=-105; DM=-105;
...
                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-105; BD=-105;
/M: SY='F';  M= -27, -34, -30,  -3,  49, -39, -26,  -9,  31,  13,  32,   6, -37, -23, -17, -28, -22,  18, -28,  -9;
/M: SY='E';  M=   7, -35,  36,  42, -33, -29, -19, -22, -17,  -2,   3,  40, -30, -13, -24, -18, -18,   7, -48, -31;
/I:         I=-9; MD=-9;
/M: SY='C';  M= -30,  64, -52, -47,  39, -51, -44,  18, -45,  21, -11, -44, -51, -47, -45, -38, -27,  33, -37, -16; D=-9;
/I:         I=-9; MD=-9;
/M: SY='P';  M= -28, -46, -28, -18, -47, -35, -32, -40,  42, -45, -34, -24,  73, -21, -16,  -7,  24, -38, -46, -40; D=-9;
/I:         I=-9; MD=-9;
/M: SY='D';  M= -33, -46,  67,  24, -48, -33,  56, -52,   1, -47, -40,  27, -33, -15, -22, -22, -25, -49, -63, -30; D=-9;
/I:         I=-9; MD=-9;
/M: SY='S';  M=   0, -39,  16, -22, -47,  23, -32, -45,  21, -46, -39, -16, -34, -22, -24,  32,  16, -38, -50, -38; D=-9;
/I:         I=-9; MD=-9;
/M: SY='K';  M= -31, -44, -16,   8, -46, -34, -20, -47,  57, -46, -34,  39, -34,  -8,  39, -22, -24, -43, -45, -34; D=-9;
/I:         I=-9; MD=-9;
/M: SY='G';  M= -17, -49,  18, -35, -57,  46, -37, -58, -17, -58, -49,  26, -44, -35, -41, -24,  -6, -53, -58, -50; D=-9;
/I:         I=-9; MD=-9;
/M: SY='Y';  M=  10, -52, -45, -48, -32, -47, -38, -45, -44, -47, -42,  -2, -53, -44, -48, -30,  25, -41, -42,  41; D=-9;
/I:         I=-9; MI=0; MD=-9; IM=0; DM=-9;
/M: SY='T';  M=  10, -42, -35, -28, -50, -40, -38, -40, -29, -42, -36, -26, -39,  39, -34, -16,  52, -33, -57, -42; D=-9;
/I:         I=-9; DM=-9;
/M: SY='C';  M= -39, 113, -54, -52, -40, -52, -49, -51, -49, -45, -43, -45,  23, -55, -56, -40, -38, -44, -58,   7; D=-9;
/I:         I=-9; DM=-9;
/M: SY='I';  M= -38, -47, -53, -51, -27, -59, -52,  45, -48,  18, -14, -44, -48, -47, -52, -37,  26,  -6, -52, -34; D=-9;
/I:         I=-9; DM=-9;
/M: SY='Y';  M=  14, -47, -51, -46,   2, -45, -28, -25, -43,  -6,  51, -46, -51, -37, -42, -36, -36, -27, -26,  56; D=-9;
/I:         I=-9; DM=-9;
/M: SY='A';  M=  59, -37, -43, -36, -51, -27, -46, -41, -38, -43, -37, -37, -42, -36, -43, -17,   2, -28, -53, -47; D=-9;
/I:         I=-9; DM=-9;
/M: SY='K';  M=   2, -48,  25,   9, -55, -38, -33, -52,  27, -52, -45,  10, -40, -24, -23,  -9,   1, -45, -59, -45; D=-9;
/I:         I=-9; DM=-9;
/M: SY='W';  M= -43, -50, -56, -51,  39, -53, -51, -28, -47,   8, -27, -48, -52, -49, -49, -39,  24, -32,  94, -13; D=-9;
/I:         I=-9; DM=-9;
/M: SY='S';  M= -12, -47, -27,  22, -53,  -7, -35, -45, -13, -49, -43, -27, -40,  12, -32,  38, -24, -18, -56, -44; D=-9;
/I:         I=-9; DM=-9;
/M: SY='M';  M=  16, -47, -47, -34, -41, -43, -37,  -2, -35, -23,  51, -40, -46,  38, -36, -31, -33,   4, -52, -36; D=-9;
/I:         I=-9; DM=-9;
/M: SY='N';  M=  -8, -45,  21, -30, -50, -32, -29, -10, -30, -48, -41,  59, -46, -30, -38,   3,  -9, -39, -66, -45; D=-9;
/I:         I=-9; DM=-9;
/M: SY='F';  M= -45, -48, -59, -57,  69, -59, -49,  21, -52, -16, -23, -49, -55, -58, -52, -44,  -3,  -4, -28,  -7; D=-9;
/I:         I=-9; DM=-9;
/M: SY='T';  M=   7, -41, -36, -14, -12, -42, -42, -34, -10, -12, -32, -30, -40, -35, -37,  -8,  48, -29, -54, -37; D=-9;
/I:         I=-9; DM=-9;
/M: SY='V';  M= -33, -47, -46, -40, -36, -55, -50,  23,  21, -24, -24, -39, -46, -38, -32, -35,  12,  32, -56, -38; D=-9;
/I:         I=-9; DM=-9;
/M: SY='P';  M= -34, -53, -36, -30, -53, -41, -38, -23, -28, -48, -40, -10,  55,  18,   0,   8,  16, -41, -56, -46; D=-9;
/I:         I=-9; DM=-9;
/M: SY='Y';  M= -44, -56, -48, -48,  -3, -54, -20, -26, -43, -29, -26, -49,   8, -40, -42, -42, -38,   2, -12,  85; D=-9;
/I:         I=-9; DM=-9;
/M: SY='E';  M= -36, -55,  22,  51, -54, -47, -30, -50, -23, -19, -41, -29, -38,  27, -30,  -7, -34, -47, -57, -44; D=-9;
/I:         I=-9; DM=-9;
/M: SY='T';  M= -42, -56, -41, -39, -62, -51, -46, -53, -39, -57, -49,   0,  10,  20, -46, -12,  39, -48, -70, -54; D=-9;
/I:         I=-9; DM=-9;
/M: SY='P';  M=  -2, -50,  -6, -34, -49, -19, -41, -43, -15, -18, -38,  -4,  25, -36,   1, -28,  21, -40, -59, -46; D=-9;
/I:         I=-9; DM=-9;
/M: SY='T';  M=  11, -39, -33, -35, -47, -34,   4, -41, -34, -45, -39,  -2, -39, -33, -40,  23,  47, -33, -61, -41; D=-9;
/I:         I=-9; DM=-9;
/M: SY='N';  M= -32, -47, -25, -35, -52,  26, -30, -52,   9, -38, -44,  52, -45, -29, -31,   7, -28, -51, -59, -47; D=-9;
/I:         I=-9; DM=-9;
/M: SY='Q';  M= -15, -53, -33, -19, -58, -38, -31, -51,  16, -51, -40, -27,  11,  58, -20,  21, -29, -49, -52, -42; D=-9;
/I:         I=-9; DM=-9;
/M: SY='T';  M=   4, -44, -32,  -2, -50, -41, -39, -40,  10, -43, -38, -27, -38,  13, -28,  -3,  41, -21, -57, -43; D=-9;
/I:         I=-9; DM=-9;
/M: SY='N';  M= -44, -55, -36, -45, -41, -44, -36, -20, -41, -12, -38,  42,  24, -40, -47,  -7, -34, -43, -55,   7; D=-9;
/I:         I=-9; DM=-9;
/M: SY='H';  M= -13, -50, -33, -12, -48, -44,  58, -44,  38, -43,  -3, -26, -42, -23, -17, -14, -12, -23, -58, -32; D=-9;
/I:         I=-9; DM=-9;
/M: SY='T';  M=  -6, -43, -28, -29, -50, -37, -34, -43,  -4, -46, -39,  28, -40,  23, -30,  -6,  44, -37, -60, -43; D=-9;
/I:         I=-9; DM=-9;
/M: SY='F';  M= -37, -45, -53, -51,  40, -57, -51,  21, -48, -19, -23, -43, -50, -52, -51, -35,  26,  22, -43, -21; D=-9;
/I:         I=-9; DM=-9;
/M: SY='T';  M= -10, -42, -12,  -2, -38, -44, -41, -31, -36,  10, -28, -31, -42, -34, -42,   3,  42, -28, -58, -40; D=-9;
/I:         I=-9; DM=-9;
/M: SY='I';  M=  14, -46, -57, -51,  18, -50, -49,  26, -50,  24, -16, -51, -53, -47, -51, -40, -36, -13, -43, -27; D=-9;
/I:         I=-9; DM=-9;
/M: SY='P';  M=  14, -49, -39, -33, -55, -33, -42, -47, -37, -53, -44, -35,  63, -35, -45,  28, -10, -42, -56, -50; D=-9;
/I:         I=-9; DM=-9;
/M: SY='R';  M=   4, -47,   2, -14, -46, -42, -39, -29, -25, -39, -36, -33, -47, -29,  29,  11, -28,  16, -59, -42; D=-9;
/I:         I=-9; DM=-9;
/M: SY='P';  M= -34, -53,  11, -31,  -7, -19,  -1, -45, -35, -23, -40, -31,  50, -35, -17,  21, -29, -46, -54, -38; D=-9;
/I:         I=-9; DM=-9;
/M: SY='M';  M=  25, -45,   8, -31, -48,  -3,   2, -42,  -4, -39,  30, -29, -43, -31, -35,   6, -30, -37, -56, -40; D=-9;
/I:         I=-9; DM=-9;
/M: SY='D';  M= -37, -52,  44,  25, -55, -45, -33, -45,   5, -48, -45,  -3, -40,   0, -29, -28,   9, -17, -64, -45; D=-9;
/I:         I=-9; DM=-9;
/M: SY='V';  M=  -9, -44,   0, -43, -39,   5, -52, -11, -45, -28, -28, -39, -49, -46, -49, -33,  -3,  45, -62, -42; D=-9;
/I:         I=-9; DM=-9;
/M: SY='T';  M= -35, -44, -36, -39, -31, -46,  39, -31, -37,  -1, -27,   3, -45, -35, -40, -11,  41, -17, -52,  13; D=-9;
/I:         I=-9; DM=-9;
/M: SY='Y';  M= -45, -56, -49, -50, -27, -58,  15,  30, -21, -17, -26, -14, -53, -43, -45, -41,   5, -21, -43,  32; D=-9;
/I:         I=-9; DM=-9;
/M: SY='N';  M= -42, -53,   4, -34, -62, -36, -30, -60, -32, -65, -53,  62, -54,   9, -39,   4, -31, -60, -74, -53; D=-9;
/I:         I=-9; DM=-9;
/M: SY='G';  M= -35, -56, -42, -48, -62,  43, -48, -64, -11, -64, -54,  -8, -50, -41, -19,  -3,  -4, -58, -61, -56; D=-9;
/I:         I=-9; DM=-9;
/M: SY='S';  M=  -3, -47, -40, -41, -58, -33, -43, -56, -41, -60, -53, -29, -47, -33, -45,  58, -21, -48, -65, -50; D=-9;
/I:         I=-9; DM=-9;
/M: SY='S';  M=  -4, -48, -43, -43, -55, -36, -46, -28, -43, -53, -48, -32, -49, -36, -47,  52, -22, -23, -65, -49; D=-9;
/I:         I=-9; DM=-9;
/M: SY='C';  M= -45, 112, -55, -11, -56, -60, -60, -63, -54, -53, -53, -49, -69, -58, -62, -47, -45, -51, -82, -65; D=-9;
/I:         I=-9; DM=-9;
/M: SY='G';  M= -33, -58, -47, -57, -64,  62, -54, -69, -52, -66, -57, -33, -51, -50, -59, -31,  -7, -62, -59, -60; D=-9;
/I:         I=-9; MI=0; MD=-9; IM=0; DM=-9;
/M: SY='E';  M= -33, -49,  37,  38, -55, -43, -34, -52, -27, -51, -48, -22, -36, -23, -35,   7,  27, -45, -64, -46; D=-9;
/I:         I=-9; DM=-9;
/M: SY='D';  M= -44, -50,  52, -24,  33, -39, -29, -47, -33, -44, -45,  45, -50, -35, -40, -31, -32, -49, -52, -27; D=-9;
/I:         I=-9; DM=-9;
/M: SY='Q';  M=  -1, -50, -34,   2, -53,   3, -36, -40, -12, -44, -37, -31, -43,  45,  -1, -26,   0,  -9, -53, -42; D=-9;
/I:         I=-9; DM=-9;
/M: SY='N';  M= -29, -44,   8, -29, -51, -15, -33, -49,   6, -52, -45,  32, -41, -28, -31,  25,  26, -43, -62, -44; D=-9;
/I:         I=-9; DM=-9;
/M: SY='A';  M=  41, -34,  28,  -6, -44,  11, -32, -36, -27, -39, -34, -19, -33, -24, -33,  17,   7, -15, -49, -38; D=-9;
/I:         I=-9; DM=-9;
/M: SY='P';  M=  45, -35, -29, -20, -41, -21, -31, -28,   8, -35, -27, -26,  69, -22, -26,   7, -16,  -6, -41, -36;
/M: SY='T';  M= -16, -31, -23, -20, -29, -29,  27,   6,  27, -10, -19, -14, -28, -17, -17,  35,  44,   0, -45, -24;
/M: SY='L';  M= -29, -35, -48, -43,  25, -50, -37,  48, -41,  51,   4, -43, -44, -37, -41, -38, -24,  14, -31, -13;
/M: SY='V';  M=   7, -30, -36, -29, -19, -37, -33,   0,  10,  25,  32, -29, -35, -27, -25, -21,  25,  39, -42, -23;
/M: SY='I';  M= -26, -40, -43, -38, -18, -46, -42,  65, -36,  -2,  28, -36,  41, -35, -41, -31,   2,  24, -40, -24;
/M: SY='Q';  M=   9, -35, -18,   6, -37, -25, -21, -30,   7,  -5, -23,  21,  29,  44, -17,  24,  10, -28, -42, -30;
/M: SY='F';  M= -33, -33, -43, -41,  92, -43, -29, -14, -37,  -7, -15, -32, -42, -45, -36, -27,  27, -17,  -9,  23;
/I:         I=-6; MD=-6;
/M: SY='G';  M=   2, -37, -30, -37, -44,  63, -37, -43, -32, -43, -36, -17, -32, -32, -40, -11,  40, -35, -45, -41; D=-6;
/I:         I=-6; MD=-6;
/M: SY='R';  M= -24, -39, -27,  -7,   1, -34, -28,   0, -19, -27,  12,  18,  12, -22,  25,  21,  16,  -3, -45, -27; D=-6;
/I:         I=-6; MD=-6;
/M: SY='P';  M=  -3, -39, -29, -31, -45,  43, -36, -41, -30, -44, -36, -20,  45, -30, -38,  14,  35, -35, -47, -41; D=-6;
/I:         I=-6; MD=-6;
/M: SY='H';  M= -11, -43, -35, -29,   9, -41,  65, -17, -32, -15, -19, -30,  40,   2, -32, -29, -27,  24, -39,  21; D=-6;
/I:         I=-6; MD=-6;
/M: SY='T';  M= -16, -30, -26, -28, -34, -28, -32, -28, -26,  -9, -27, -15, -30, -24, -32,  47,  61, -22, -52, -32; D=-6;
/I:         I=-6; MD=-6;
/M: SY='W';  M= -10, -41, -46, -39, -16, -41, -46, -16, -36,  23, -18, -39, -41, -36, -40, -28,  33,  -2, 112, -14; D=-6;
/I:         I=-6; MD=-6;
/M: SY='T';  M=   4, -33, -25, -24, -37, -30, -31,  -4,  25, -33, -28,   0, -30, -21, -20,  24,  51, -22, -49, -33; D=-6;
/I:         I=-6; MD=-6;
/M: SY='L';  M=  -4, -37, -28,  12, -25, -13, -31,   5, -30,  28, -14,  19, -40, -26, -35,  -1, -22,  13, -46, -30; D=-6;
/I:         I=-6; MD=-6;
/M: SY='N';  M= -23, -34,  -8, -26, -37, -25, -21, -16, -19, -13, -29,  61, -36, -20,   1,  29,  25, -29, -54, -34; D=-6;
/I:         I=-6; MD=-6;
/M: SY='F';  M= -14, -37, -45, -41,  77, -44, -35, -18, -39,   1, -19, -36,   5, -45, -41, -29,  23, -20, -20,   1; D=-6;
/I:         I=-6; MD=-6;
/M: SY='T';  M=   6, -32, -27, -29, -39,  13, -36, -31, -27, -35, -30, -18,  16, -30, -35,  -7,  69, -23, -51, -36; D=-6;
/I:         I=-6; MD=-6;
/M: SY='R';  M= -30, -46, -31, -23, -43, -41, -29,  -8,  36, -39, -32, -23, -38, -16,  51,   7,  13, -32, -47, -34; D=-6;
/I:         I=-6; MD=-6;
/M: SY='N';  M=  -4, -40, -16,  15, -48, -27, -25, -45, -23, -49, -40,  52,  23, -20, -31,  25,   4, -41, -56, -42; D=-6;
/I:         I=-6; MD=-6;
/M: SY='A';  M=  34, -34,   1,  -8, -43, -24, -30, -35, -25, -39, -32,  22,  28, -24, -32,   8,  33, -28, -50, -38; D=-6;
/I:         I=-6; MD=-6;
/M: SY='T';  M= -17, -31, -27, -29, -34, -30, -34,   9, -27, -29, -26, -16, -30, -26, -33,  41,  63, -16, -52, -32; D=-6;
/I:         I=-6; MD=-6;
/M: SY='R';  M= -23, -39, -28, -24, -36, -35,  35,  -8, -13, -31,   8, -18, -35,   0,  42,  26,  34, -27, -49, -27; D=-6;
/I:         I=-6; MD=-6;
/M: SY='Y';  M= -38, -49, -34, -36,   8, -44,  58, -28, -31, -23, -18, -32, -48, -25, -28, -32, -33, -33,  -2,  98; D=-6;
/I:         I=-6; MD=-6;
/M: SY='S';  M= -18, -36, -25,  -7, -15, -29, -27, -34, -15, -37, -31, -17, -33,  12,  28,  48,  31, -16, -47, -30; D=-6;
/I:         I=-6; MD=-6;
/M: SY='V';  M= -35, -48, -58, -56,   9,  -2, -55,  29, -52,   6, -18, -50, -54, -52, -54, -44, -34,  32, -49, -30; D=-6;
/I:         I=-6; MD=-6;
/M: SY='Q';  M= -10, -50,   2, -28, -49,  -2,  17, -30, -32, -39, -34, -10, -46,  39, -35,  -9, -32,  15, -59, -39; D=-6;
/I:         I=-6; MD=-6;
/M: SY='D';  M=   3, -38,  29, -20, -37, -31,  11, -32, -23,  -3, -27,  -3,  24, -24,   4,  11,  28, -29, -52, -32; D=-6;
/I:         I=-6; MD=-6;
/M: SY='M';  M= -26, -35, -39, -37, -21, -44, -35,  25, -34,  17,  53, -29, -36, -32, -37, -22,  49,   1, -46, -25; D=-6;
/I:         I=-6; MD=-6;
/M: SY='W';  M= -34, -51, -43, -35, -33, -48, -38,   5,  -5, -33, -30, -36, -47,  22, -12,   4,   0,   6,  28,  15; D=-6;
/I:         I=-6; MD=-6;
/M: SY='F';  M=  -1, -45, -56, -50,  56, -49, -43, -23, -49,  12,  16, -48, -55, -48, -48, -11, -36, -27, -33, -13; D=-6;
/I:         I=-6; MD=-6;
/M: SY='T';  M=  -3, -41, -37, -37, -44, -38,  19, -32, -37, -40, -36, -27, -41, -34, -41,  28,  38,   3, -63, -39; D=-6;
/I:         I=-6; MD=-6;
/M: SY='Y';  M= -43, -57, -44, -43,  -4, -50, -18, -37,  -8, -35, -30, -43,  -1, -34, -34, -12, -38, -41, -12,  85; D=-6;
/I:         I=-6; MD=-6;
/M: SY='N';  M= -28, -33,  -6, -25, -42, -20, -14, -40, -17, -47, -35,  88, -38, -19, -25, -10,  28, -39, -62, -38; D=-6;
/I:         I=-6; MD=-6;
/M: SY='T';  M= -26, -33, -25, -32, -26, -36, -29,  -5, -28,  22, -16,  37, -36, -29, -34, -15,  56, -17, -51, -30; D=-6;
/I:         I=-6; MD=-6;
/M: SY='S';  M= -12, -32, -20, -26, -42,   6, -25, -41, -24, -45, -37,  30, -32, -18, -29,  66,  12, -35, -51, -35; D=-6;
/I:         I=-6; MD=-6;
/M: SY='H';  M= -36, -48,  75,  -6, -46, -34,  84, -54, -24, -45, -37,  -5, -35, -19, -26, -24, -29, -51, -71, -21; D=-6;
/I:         I=-6; MD=-6;
/M: SY='T';  M=  -9, -34, -24, -26, -38,  -5, -27, -32,   2, -33,  18,  22, -32, -21,  17,  14,  50, -27, -50, -33; D=-6;
/I:         I=-6; MD=-6;
/M: SY='T';  M=   6, -36,  -2,   7, -40, -31,   6, -11,  -9, -34, -29,  24,   3,   0, -27, -12,  49, -25, -52, -34; D=-6;
/I:         I=-6; MD=-6;
/M: SY='T';  M=  -4, -36, -35, -32,  18, -39,  27, -16, -33,   7, -18, -28,  27, -33, -36, -20,  41,   9, -43, -21; D=-6;
/I:         I=-6; MD=-6;
/M: SY='F';  M= -33, -38, -42, -39,  77, -42, -35, -22, -37, -18, -23, -33,  26, -43, -40,  -1,  24, -24, -20,   0; D=-6;
/I:         I=-6; MD=-6;
/M: SY='P';  M= -30, -49, -38, -30, -40, -39, -40, -25, -34,  -7, -28, -38,  83, -36, -43,  -3,   2,   3, -50, -42; D=-6;
/I:         I=-6; MD=-6;
/M: SY='G';  M= -26, -41,  33, -25, -47,  35,  18, -47, -28, -47, -40,  33, -36, -27, -35,  -3,  28, -42, -57, -38; D=-6;
/I:         I=-6; MD=-6;
/M: SY='A';  M=  46, -38, -29,  15, -49, -28, -37, -42,  -4, -43, -37, -29, -36, -24, -31,  10,   2, -31, -50, -43; D=-6;
/I:         I=-6; MD=-6;
/M: SY='S';  M= -21, -35,   7,   0, -29, -36, -35,   8, -30,   1, -20, -24, -35, -27, -35,  27,  27,  25, -51, -31; D=-6;
/I:         I=-6; MD=-6;
/M: SY='S';  M=  -2, -36,   9,   2, -43, -26, -27, -39,  -2, -42, -35,   3,  13, -18,  -1,  42,  31, -32, -51, -36; D=-6;
/I:         I=-6; MD=-6;
/M: SY='K';  M= -27, -41, -23,  -1, -37, -37,  40,  -1,  51, -32, -25,   8, -34, -15,  -8,  -4,  -7,   5, -48, -28; D=-6;
/I:         I=-6; MD=-6;
/M: SY='G';  M= -18, -45, -28,  -2, -50,  77, -35, -57, -30, -52, -42, -18, -35, -29, -11, -18, -35, -50, -42, -44; D=-6;
/I:         I=-6; MD=-6;
/M: SY='P';  M= -26, -42, -38, -33, -29, -40, -40,  30, -35,   2, -17, -34,  60, -34, -41,   7,  13,  10, -46, -33; D=-6;
/I:         I=-6; MD=-6;
/M: SY='H';  M= -12, -38, -30, -27, -28,  -2,  35,   5,  21,  -1, -21, -21, -35, -23, -22,  12,  25, -22, -42,   2; D=-6;
/I:         I=-6; MI=0; MD=-6; IM=0; DM=-6;
/M: SY='T';  M= -17, -29, -24, -27, -36, -30, -33, -29, -25, -34, -29, -13, -27, -26, -32,  33,  75, -21, -54, -33; D=-6;
/I:         I=-6; DM=-6;
/M: SY='V';  M=  -2, -35, -44, -40, -24, -43, -45,  34, -38, -10,  13, -36, -41, -37, -41,   5,  -1,  52, -50, -29; D=-6;
/I:         I=-6; DM=-6;
/M: SY='T';  M=  -9, -35,  29,   5, -39, -33, -31,  -5,  -2, -33, -30, -14, -29, -22, -28,  14,  55, -23, -53, -34; D=-6;
/I:         I=-6; DM=-6;
/M: SY='H';  M=  11, -40, -22,   3, -40, -28,  68, -23, -25, -38, -29,   8,  28, -19, -28,  25,   3, -34, -53, -26; D=-6;
/I:         I=-6; MI=0; MD=-6; IM=0; DM=-6;
/M: SY='P';  M=  -1, -45, -31, -26, -42, -31, -33, -16, -29, -25,   8,   2,  81, -29, -38,  10,  -4, -31, -47, -40; D=-6;
/I:         I=-6; DM=-6;
/M: SY='T';  M=  13, -39, -38,  -8,  33, -41, -39, -27, -35,  -9, -27, -33, -41,  -9, -39, -22,  36, -14, -41, -23; D=-6;
/I:         I=-6; DM=-6;
/M: SY='H';  M=   8, -39,  36, -20, -38, -15,  41, -34, -27,  -6, -27,   9,  14, -25, -32,  -5,  25, -31, -54, -30; D=-6;
/I:         I=-6; DM=-6;
/M: SY='T';  M= -24, -36, -37, -39,   4,   3, -42,  40, -35, -16, -17, -26, -35, -36, -41,  -8,  49,   7, -44, -26; D=-6;
/I:         I=-6; DM=-6;
/M: SY='T';  M= -24, -39, -24,  -5, -42, -36, -29, -37,  31, -39, -31, -18,  25,   0,  20,   3,  50, -31, -48, -34; D=-6;
/I:         I=-6; DM=-6;
/M: SY='A';  M=  29, -36, -36, -33, -33,  11, -37,  19, -29, -15, -22, -28, -37, -28,   2,  21, -20,  11, -45, -33; D=-6;
/I:         I=-6; DM=-6;
/M: SY='P';  M=  -6, -46,  36,   5, -46, -34,  54, -43, -25, -43, -34, -19,  62, -23, -32, -21,  14, -40, -56, -32; D=-6;
/I:         I=-6; DM=-6;
/M: SY='L';  M= -25, -38, -36, -37, -23,  10, -33,  20, -32,  32, -12,   3, -42, -29, -10,  22, -22, -14, -43, -28; D=-6;
/I:         I=-6; DM=-6;
/M: SY='N';  M= -26, -38,  28, -22, -42,   9, -19, -40, -22, -17, -34,  69,   0, -21, -29,  13, -17, -40, -56, -38; D=-6;
/I:         I=-6; DM=-6;
/M: SY='S';  M=  12, -34,  17, -21, -38, -29, -32, -24,  19, -33, -29, -18, -33, -22, -23,  29,  24,  14, -51, -34; D=-6;
/I:         I=-6; DM=-6;
/M: SY='T';  M=   7, -33, -32, -30, -29, -37, -36,  14,   0,  -4,  17, -23, -32, -28, -30, -13,  59, -12, -48, -30; D=-6;
/I:         I=-6; DM=-6;
/M: SY='Y';  M= -32, -41, -45, -44,  45, -48, -24,   7, -38, -12, -15, -41, -48, -39, -37, -33,  -7,  31, -13,  70; D=-6;
/I:         I=-6; DM=-6;
/M: SY='R';  M= -35, -49, -26, -22, -49, -39,  24, -53,  38, -49, -38,  27, -42, -15,  50,  -7, -29, -49, -52, -35; D=-6;
/I:         I=-6; DM=-6;
/M: SY='C';  M= -36, 113, -44, -43, -44, -47,  57, -52, -43, -42, -38, -33,   4, -44, -46, -35, -35, -43, -72, -39; D=-6;
/I:         I=-6; DM=-6;
/M: SY='I';  M= -30, -41, -35, -42, -31, -44, -40,  33, -37, -11, -20,  30, -43, -37, -42, -13,  27,  19, -56, -35; D=-6;
/I:         I=-6; DM=-6;
/M: SY='S';  M= -17, -36, -27, -31, -45, -14, -32, -43, -29, -47, -40,   9, -36, -24, -35,  58,  32, -36, -57, -39; D=-6;
/I:         I=-6; DM=-6;
/M: SY='G';  M= -15, -46,  -7, -16, -42,  30, -35, -32, -32,  -7, -32,  18,   6, -32,  -9,  -8, -30,  -5, -53, -41; D=-6;
/I:         I=-6; DM=-6;
/M: SY='N';  M= -30, -43, -26,   7, -37, -38,  20,  -2, -26,   0, -27,  21, -41, -24,   3,  20,   3, -29, -54, -34; D=-6;
/I:         I=-6; DM=-6;
/M: SY='T';  M=  -6, -40, -34, -28, -42, -40, -37, -24, -26, -33, -29, -26, -38,  32,  -9,   4,  45,  14, -55, -37; D=-6;
/I:         I=-6; DM=-6;
/M: SY='V';  M=  -7, -39, -47, -44,   9, -49, -44,   8, -42,  -2, -19, -40, -46, -43, -45, -29,  27,  35, -43,   9; D=-6;
/I:         I=-6; DM=-6;
/M: SY='H';  M= -33, -48, -24,   3, -41, -41,  42, -35,  -7, -39, -31,  24, -41,  41,   3, -25,  -1,  -3, -51,   0; D=-6;
/I:         I=-6; DM=-6;
/M: SY='M';  M= -30, -43, -43, -36, -30, -41, -34, -21,  -5,  17,  55, -35,  26, -30, -34,  16, -10, -25, -48, -32; D=-6;
/I:         I=-6; DM=-6;
/M: SY='E';  M= -27, -45,  -3,  23, -49,  17, -29, -47,  -8, -29, -39,  20, -37,  11, -29,  17,  -2, -44, -53, -42; D=-6;
/I:         I=-6; DM=-6;
/M: SY='N';  M= -33, -45,  12, -29, -52,  18, -22, -51, -26, -57, -44,  72,  18, -27, -34, -20, -24, -52, -62, -47; D=-6;
/I:         I=-6; DM=-6;
/M: SY='V';  M= -27, -44, -46, -33, -35, -51, -45,  -3, -35, -20, -20, -42,   7,  37, -37, -34, -26,  55, -56, -35; D=-6;
/I:         I=-6; DM=-6;
/M: SY='T';  M= -24, -35, -35, -36, -37, -42, -43, -18, -33, -30, -28, -25, -36, -36, -40,   4,  65,  22, -60, -37; D=-6;
/I:         I=-6; DM=-6;
/M: SY='Q';  M=  -7, -42, -34, -24, -43, -42, -35, -22, -26, -31, -27, -27, -39,  55, -29, -19,  37,  19, -53, -36; D=-6;
/I:         I=-6; DM=-6;
/M: SY='H';  M=  -9, -41, -38, -36, -30, -45,  35,   8,  -9,  14, -19,  -8, -42, -33, -35, -26,  30,  -6, -54, -30; D=-6;
/I:         I=-6; DM=-6;
/M: SY='Y';  M= -35, -47, -43, -39,  11, -46, -30,   9, -39,  16, -17, -41,  44, -37, -41, -14,  -1, -20, -27,  46; D=-6;
/I:         I=-6; DM=-6;
/M: SY='W';  M=   3, -49, -36, -30, -28, -14,  62, -46,   1, -41, -33, -28, -41, -24,   7,   2, -33, -45,  94,  12; D=-6;
/I:         I=-6; DM=-6;
/M: SY='D';  M=  -5, -44,  64, -14, -51,   4, -28, -48, -25, -49, -44,   5, -36, -25,  -8,   1,  14, -42, -61, -40; D=-6;
/I:         I=-6; DM=-6;
/M: SY='I';  M=  17, -41, -48, -41, -26, -43, -46,  28, -42,  17, -13, -44,  25, -40, -45, -32, -26,  23, -47, -33; D=-6;
/I:         I=-6; DM=-6;
/M: SY='H';  M=   2, -39, -31, -27,   6, -35,  43, -34,  19, -12, -27, -22, -37, -25, -23,  12,  30, -30, -46, -24; D=-6;
/I:         I=-6; DM=-6;
/M: SY='I';  M= -32, -40, -48, -45, -20, -53, -45,  43, -43,  30,  -7, -40, -44, -41, -46, -33,  27,  12, -47, -28; D=-6;
/I:         I=-6; DM=-6;
/M: SY='Q';  M=   5, -47, -22,  27, -53, -36, -25, -43, -16, -41, -32, -24,  15,  67, -21, -18,  12, -39, -47, -37; D=-6;
/I:         I=-6; DM=-6;
/M: SY='A';  M=  60, -29, -31, -25, -38, -17, -33, -30, -28, -16, -26, -25,   9, -23, -32,  28, -15, -20, -42, -35; D=-6;
/I:         I=-6; DM=-6;
/M: SY='H';  M= -38, -43, -35, -35,  66, -43,  78, -26, -33, -17, -17, -27, -45, -30, -29, -32, -33, -30, -13,  61; D=-6;
/I:         I=-6; DM=-6;
/M: SY='L';  M= -32, -41, -42,  -3, -22, -52, -37,  -6,   7,  34,  33, -42, -46, -31, -31, -39, -29,  23, -47, -29; D=-6;
/I:         I=-6; DM=-6;
/M: SY='Q';  M=  23, -33, -22, -14, -40,  15, -22, -35,   3, -21, -26, -14, -29,  51, -17,  46, -12, -29, -39, -29;
/M: SY='N';  M= -19, -30,  -7, -18, -38, -18,  24, -35, -14, -39, -29,  75, -31,  13, -20,  28,  33, -33, -54, -29;
/M: SY='G';  M=  32, -30, -24, -27, -39,  47, -29, -36, -25, -37, -30,   4, -28, -23, -31,  27,  31, -27, -42, -34;
/M: SY='T';  M= -14, -27, -16, -24, -35,  14, -24, -30, -20, -34, -28,  39, -26, -21, -27,  29,  66, -23, -50, -31;
/I:         I=-9; MD=-10;
/M: SY='F';  M= -28, -39, -44, -32,  48, -47, -36,  -3, -33,   7, -13, -38, -46,  38, -33, -32, -26,  41, -32, -11; D=-9;
/I:         I=-9; MD=-10;
/M: SY='S';  M= -15, -37, -24, -23, -43,  11,  24, -45,  13, -45, -36, -13, -33, -15,   9,  60, -12, -38, -48, -31; D=-9;
/I:         I=-9; MD=-10;
/M: SY='P';  M= -30, -49, -27, -15, -49, -37, -28, -42,  42, -45, -33, -24,  69,  24,  12, -24,   2, -42, -44, -38; D=-9;
/I:         I=-9; MD=-10;
/M: SY='T';  M= -29, -42, -22,  20, -44, -19,   2, -32,  -2, -38, -33,  25, -37,   0, -28, -20,  35,   3, -58, -38; D=-9;
/I:         I=-9; MD=-10;
/M: SY='E';  M= -25, -43, -10,  61, -41, -40, -24, -32, -15, -11, -28, -24, -28,  30, -22,   0,  11, -10, -47, -35; D=-9;
/I:         I=-9; MD=-10;
/M: SY='N';  M= -24, -38, -25, -26,  16, -31, -27,  -7, -25, -30, -27,  34,  27,  17, -31,  17,  31,  -9, -44, -26; D=-9;
/I:         I=-9; MD=-10;
/M: SY='T';  M= -21, -36, -32, -30, -32,  -9,   9,  -3, -21,  -7, -22, -22, -36, -25,  23,  21,  38,  11, -50, -29; D=-9;
/I:         I=-9; MD=-10;
/M: SY='C';  M= -31, 113, -42, -43, -38, -45,  38,  -7, -41, -33, -31, -30, -50, -43, -45, -28,  14, -28, -66, -38; D=-9;
/I:         I=-9; MD=-10;
/M: SY='D';  M=  25, -40,  33,  32, -46, -32, -31, -35, -11, -39, -36, -21, -33, -20, -29,   1,   7,  -6, -53, -39; D=-9;
/I:         I=-9; MD=-10;
/M: SY='Q';  M=   3, -45, -21,  30, -50, -35, -28, -43,   4, -43, -34, -24,  28,  43, -21,   4,  16, -38, -48, -38; D=-9;
/I:         I=-9; MD=-10;
/M: SY='D';  M= -29, -47,  74,  12, -54,  10, -26, -54, -25, -53, -49,  -9, -35, -22, -33,  12, -25, -49, -62, -41; D=-9;
/I:         I=-9; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='H';  M= -19, -62, -51, -47, -59,  -8,  37, -53,   4, -36, -47, -42, -58, -43, -17, -43, -17, -25, -71, -48; D=-9;
/I:         I=-9; DM=-10;
/M: SY='P';  M= -32, -52,   9, -16, -51, -33, -28, -43,  17, -50, -37,  21,  85,   7, -24, -25, -24, -46, -48, -43; D=-9;
/I:         I=-9; DM=-10;
/M: SY='T';  M= -18, -34, -27, -28, -38,  10, -31, -31, -20, -36, -31, -17, -32, -23,  19,  35,  51,  -7, -50, -34; D=-9;
/I:         I=-9; DM=-10;
/M: SY='P';  M= -19, -49, -40, -34,  16, -39, -41, -36, -37, -41, -37, -36,  70, -38, -45,  11,  13, -22, -46, -34; D=-9;
/I:         I=-9; DM=-10;
/M: SY='T';  M= -19, -32, -25, -26, -38, -32, -31, -32, -19, -35, -30, -16,   1, -23,  16,  27,  68, -24, -52, -33; D=-9;
/I:         I=-9; DM=-10;
/M: SY='T';  M= -19, -30, -23, -25, -37, -33, -31, -29, -23, -33, -28,   7, -28,   4, -30,  11,  77, -21, -54, -33; D=-9;
/I:         I=-9; DM=-10;
/M: SY='V';  M=  21, -42, -46, -40, -42, -38, -48, -18, -41, -32, -31, -40,  21, -40, -46,  13, -24,  32, -58, -43; D=-9;
/I:         I=-9; DM=-10;
/M: SY='A';  M=  36, -42, -37, -33, -51,   9, -40, -45, -33, -48, -40, -31,  33, -31, -16,  22, -24, -37, -51, -46; D=-9;
/I:         I=-9; DM=-10;
/M: SY='P';  M= -16, -62, -47, -39, -62, -48, -51, -51, -43, -59, -49, -47,  77, -47, -54, -35,  15, -50, -63, -60; D=-9;
/I:         I=-9; DM=-10;
/M: SY='H';  M=  18, -39, -35, -33, -35, -14,  53,  13, -33, -26, -22, -27,   8, -31, -36, -20,  25,  10, -53, -28; D=-9;
/I:         I=-9; DM=-10;
/M: SY='P';  M=   3, -45, -37, -29, -38, -34, -40,  19, -33, -29, -25, -35,  77, -33, -41,   9, -21,   6, -46, -39; D=-9;
/I:         I=-9; DM=-10;
/M: SY='H';  M= -26, -44, -26,   1, -39,   6,  60, -38, -27, -14, -28, -22,  56, -24, -32,   8,  14, -37, -51, -29; D=-9;
/I:         I=-9; DM=-10;
/M: SY='T';  M= -20, -35, -30, -28, -36, -35, -36, -18, -28, -29, -26, -23,  41,  -6, -35,  15,  54,  20, -52, -35; D=-9;
/I:         I=-9; DM=-10;
/M: SY='P';  M= -10, -45, -31, -25, -46, -34, -37, -35, -28, -42, -33, -29,  87, -32, -39, -18,  44, -33, -49, -43; D=-9;
/I:         I=-9; DM=-10;
/M: SY='P';  M=   4, -39, -33, -30, -38,  10, -36,  -5, -26, -31, -27, -26,  41, -29,   2,  13,  23,  11, -48, -36; D=-9;
/I:         I=-9; DM=-10;
/M: SY='P';  M= -32, -57, -33, -23, -53, -34, -36, -41, -30, -51, -38, -38, 104, -32, -42,  -6, -24, -45, -47, -49; D=-9;
/I:         I=-9; DM=-10;
/M: SY='T';  M=  10, -33, -26, -26, -41, -25, -32, -34, -26, -39, -33, -17,  29, -24, -33,  47,  47, -27, -50, -36; D=-9;
/I:         I=-9; DM=-10;
/M: SY='P';  M= -34, -49, -38, -29,   7, -40, -37, -25, -34,  12, -23, -41,  88, -36, -42, -32,  -2, -30, -41, -32; D=-9;
/I:         I=-9; DM=-10;
/M: SY='T';  M=  22, -30, -32, -31, -33, -30, -38, -13, -30, -25, -23, -24, -34, -29, -35,  24,  45,  30, -52, -33; D=-9;
/I:         I=-9; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='P';  M= -43, -65, -48, -42, -66, -49, -52, -57, -46, -65, -55, -47,  72, -47, -56,   7,  -2, -57, -67, -62; D=-9;
/I:         I=-9; DM=-10;
/M: SY='W';  M= -41, -58, -46, -38, -53, -51, -49, -31,   2, -53, -47, -38, -50,  21, -36,   5,  20, -47,  53, -43; D=-9;
/I:         I=-9; DM=-10;
/M: SY='P';  M= -31, -56, -33, -23, -52, -34, -36, -41, -30, -51, -38, -37, 104, -32, -42,  -2, -24, -45, -47, -49; D=-9;
/I:         I=-9; DM=-10;
/M: SY='T';  M= -10, -34, -30, -27, -30, -33, -31, -22,  10,  14, -20, -21, -35, -23,   1,  31,  38, -11, -47, -30; D=-9;
/I:         I=-9; DM=-10;
/M: SY='P';  M= -20, -41,  18,   5, -47, -25, -26, -43, -23, -48, -39,  15,  57, -20, -31,  47, -14, -41, -52, -40; D=-9;
/I:         I=-9; MI=0; MD=-10; IM=0; DM=-10;
/M: SY='P';  M=  16, -44, -28,   2, -41,   9, -33,  -6, -26, -35, -27, -31,  87, -26, -36, -20, -21,  -9, -41, -40;
/M: SY='T';  M=  13, -30, -20,   6, -35, -29, -28, -26,  32, -31, -25, -15,  13, -16, -15,   2,  58,  -8, -44, -31;
/M: SY='V';  M=  26, -29, -38, -33, -20, -34, -38,  27, -32,  10,  19, -31, -35, -31, -35, -18,  27,  42, -43, -25;
/M: SY='G';  M= -12, -36,  -7, -33, -12,  71, -32, -18, -30, -37, -32, -14, -32, -27, -36,  25, -21, -10, -38, -32;
/M: SY='N';  M= -25, -36,  12, -15, -35, -27,  38,   7,  22, -31, -23,  55, -31,  14,  13, -13,  23, -25, -49, -25;
/M: SY='Y';  M= -34, -45, -34, -37,  18, -41,   0, -20, -28, -16, -13, -35, -46, -24, -25, -29, -29, -25,  10, 110;
/M: SY='T';  M= -17, -31, -13,   7, -28, -24, -16, -31, -15, -33, -26,  41, -28,  28, -21,  32,  47, -27, -38,  22;
/M: SY='W';  M= -19, -34, -49, -41, -14, -46, -51,  26, -38,  -6,  -9, -44, -42, -39, -40, -32, -19,  68,  88, -16;
/M: SY='T';  M=  -1, -28, -21, -24, -27, -24, -23, -22, -19,  13, -18,  28, -30, -19,   1,  39,  45, -19, -45, -27;
/M: SY='N';  M= -22, -34,  25, -20, -42,  39, -12, -43, -16, -48, -35,  83, -34, -17, -25,  -9, -15, -43, -53, -36;
/M: SY='G';  M=   8, -34, -20, -11, -41,  65, -27, -38, -25, -41, -33,  30, -31, -23, -32,  13,  -6, -16, -42, -37;
/M: SY='N';  M= -16, -30,  -6, -20, -38, -14,  27, -39, -15, -43, -32,  76, -32, -12, -21,  51,  -6, -36, -54, -30;
/M: SY='G';  M=   0, -38,   8, -17, -43,  47, -24, -41, -12, -39, -30, -13, -30,  38,  33, -11,  22, -35, -41, -32;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='T';  M= -21, -32, -28, -26, -26, -35, -32,   0, -26,  15, -15, -21,  53, -28, -33, -11,  65, -14, -45, -29;
/M: SY='C';  M= -48, 277, -88, -88, -69, -80, -88, -83, -80, -64, -64, -61,-110, -95, -93, -54, -48, -58,-129, -90;
/M: SY='L';  M= -27, -34, -48, -42,  -8, -50, -38,  46, -41,  52,   5, -44, -43, -36, -40, -37, -23,  30, -37, -19;
/M: SY='L';  M= -28, -36, -34, -24, -15, -42,  24,  15,  24,  46,  25, -29, -38,  22, -18, -30, -25, -10, -36, -18;
/M: SY='A';  M=  61, -26, -36, -28, -25, -21, -33, -13, -30,  25, -12, -31, -34, -26, -33, -12, -18,   4, -38, -28;
/M: SY='Q';  M= -16, -35,  21,  32, -41, -26, -20, -37,   6, -37, -30, -10, -25,  41, -16,  40,  33, -31, -45, -30;
/M: SY='M';  M=  17, -31, -40, -33, -20,   6, -21,  -7, -28,  -1, 100, -28, -32, -22, -29, -22,   2, -10, -38, -19;
/M: SY='G';  M=   5, -40,  16, -22, -47,  71, -27, -48, -24, -44, -34, -12, -31,  37, -29, -12, -28, -42, -39, -36;
/M: SY='L';  M= -30, -35, -49, -43,  25, -50, -37,  50, -42,  53,   5, -43, -43, -37, -41, -39, -25,   5, -31, -13;
/M: SY='Q';  M=   0, -45, -18,   2, -51, -29, -12, -38,  -4, -33, -21, -14, -30, 102,  -4, -11, -24, -38, -35, -24;
/M: SY='L';  M= -30, -35, -48, -42,  25, -49, -34,  42, -40,  52,  39, -42, -43, -35, -39, -38, -25,   3, -31, -12;
/I:         I=-32; MD=-33;
/M: SY='N';  M= -35, -42, -12, -28, -49, -27, -16, -49, -14, -54, -41,  82, -46, -20,  28, -19, -22, -50, -63, -42; D=-32;
/I:         I=-32; MI=-33; IM=-33; DM=-33;
/M: SY='I';  M= -24, -36, -45, -42, -13, -49, -44,  66, -39,  20,   0, -36, -37, -37, -42, -30,  13,  34, -40, -21;
/M: SY='T';  M= -16, -27, -30, -29, -22, -35, -33,  -3, -27,   7,  22, -21, -30, -28, -32,  13,  59,  36, -48, -25;
/M: SY='Y';  M= -29, -43, -24,  18,  27, -39,  -9, -22, -19,   3, -14, -27, -37,  53, -19, -24, -27, -26,  -8,  76;
/I:         I=-27; MD=-28;
/M: SY='D';  M= -35, -46,  19,  11, -36, -44, -31, -26, -26,  11,   4,  14,   3, -27,   3, -31,  -1,  -9, -55, -37; D=-27;
/I:         I=-27; MD=-28;
/M: SY='K';  M= -29, -44, -26,  10, -45, -41, -33, -14,  37, -41, -35, -23, -35, -19,  10,   8,  32, -33, -51, -38; D=-27;
/I:         I=-27; MD=-28;
/M: SY='Q';  M= -37, -57, -26,  32, -59,  -8, -34, -53,  30, -52, -43, -30, -40,  38, -19, -32, -38, -31, -53, -45; D=-27;
/I:         I=-27; MD=-28;
/M: SY='D';  M= -33, -53,  43, -30, -54,  35, -40, -54, -40, -22, -47, -23, -46, -37, -47,   7, -35, -51, -61, -48; D=-27;
/I:         I=-27; MD=-28;
/M: SY='N';  M= -40, -56,   3, -46, -59,  29, -44, -47, -45, -57, -51,  35, -56, -45, -52, -35, -40,  -5, -70, -56; D=-27;
/I:         I=-27; MI=-28; IM=-28; DM=-28;
/M: SY='K';  M= -23, -38,  11,  21,  19,  -3, -22, -35,  50, -31,   3, -14, -28, -11,  12,   4,   7, -32, -34, -21;
/M: SY='N';  M=   1, -32, -11,   7, -38, -23, -19, -35,  42, -38, -29,  50, -27, -11,  -9,  17,  32, -30, -45, -31;
/M: SY='V';  M=  26, -30, -35, -30, -26, -33, -39,  19, -30, -14, -14, -30,  28, -32, -36, -16,  28,  46, -45, -29;
/M: SY='W';  M=  -3, -40, -31, -23, -26, -30, -33, -32, -17, -34, -29, -24,  32,  14,  17,   3,  42, -30, 108, -16;
/M: SY='R';  M= -24, -40, -24,  10,  24,  21, -20, -37,  -4, -31, -27, -20, -35, -13,  62,   2,  -4, -34, -29,  14;
/M: SY='I';  M=   9, -37, -33, -12, -16, -15,  26,  36,   5,   4, -10, -29,   4, -25, -26, -25, -22,  19, -31,  30;
/M: SY='F';  M= -29, -33, -43, -40,  84, -39, -30,   7, -37,  13, -12, -33, -43, -39, -36,  17, -22, -13, -13,   8;
/M: SY='N';  M= -22, -29,  -5, -23, -34, -19, -13, -21, -15, -34, -26,  88, -36, -17, -23,  -9,  17,  15, -57, -33;
/M: SY='I';  M= -27, -37, -48, -45, -10, -52, -44,  69, -41,  31,   3, -41, -40, -38, -43, -37, -21,  30, -38, -19;
/M: SY='N';  M= -24, -34,  60,  -9, -42, -19, -12, -40, -15, -44, -36,  72, -32, -15, -23,  11,  16, -38, -59, -33;
/M: SY='P';  M= -28, -50, -31, -20,  11, -31, -32, -34, -27, -40, -31, -34, 104, -30, -38,  -4, -21, -38, -37, -33;
/M: SY='N';  M=   3, -30,  -6, -20, -36, -16, -12, -33,   5, -20, -28,  83, -33, -14, -19,  17,   6, -32, -52, -32;
/M: SY='K';  M=  17, -34,  14,  14, -36,  11, -26, -32,  39, -10, -25, -14, -27, -14, -12, -12,  31, -26, -41, -31;
/M: SY='T';  M= -16, -26, -24, -26, -27, -33, -32,   1, -22, -20,  12, -13, -24, -26, -30,  -3,  82,   5, -50, -27;
/I:         I=-32; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='H';  M=  -7, -34, -15, -13, -38, -24,  51, -37,  33, -36, -26,  29, -28,  30,  -9,  32,  23, -33, -46, -23;
/I:         I=-32; MD=-33;
/M: SY='F';  M=  24, -33, -40, -35,  40, -35, -39,  -7, -12, -17, -19, -33, -40, -35, -34,   1,   0,  38, -36, -17; D=-32;
/I:         I=-32; MI=-33; IM=-33; DM=-33;
/M: SY='S';  M= -14, -33, -12,  26, -40,   5, -19, -36, -14, -37, -30,  23, -26,  40, -19,  42,  33, -31, -45, -31;
/M: SY='G';  M= -12, -40, -27, -39, -46,  87, -34, -54, -33, -49, -38, -13, -31, -30, -40, -12, -31, -47, -37, -41;
/M: SY='S';  M= -13, -30,  19, -17, -39,  13, -21, -37,   5, -40, -33,  35, -28, -15, -21,  52,  30, -31, -48, -31;
/M: SY='C';  M= -48, 277, -88, -88, -69, -80, -88, -83, -80, -64, -64, -61,-110, -95, -93, -54, -48, -58,-129, -90;
/M: SY='G';  M= -16, -36,  21,   6, -42,  39,  10, -43, -15, -42, -33,  23, -29,  22,   6,  32,   2, -38, -45, -31;
/M: SY='P';  M=  10, -33, -20, -25, -39,  33,  -3, -15, -23, -37, -29,  34,  36, -21, -30,  28,  18, -28, -45, -34;
/M: SY='Q';  M=   7, -37, -21, -12, -38, -30,  51, -27, -10, -29, -20,   4, -31,  63,  22, -12,  23,   1, -44, -22;
/M: SY='H';  M= -22, -32, -20, -22, -27, -31,  55, -22,   1,   8, -17,  29, -32, -17,  15,   4,  44, -10, -48, -21;
/I:         I=-27; MD=-28;
/M: SY='P';  M=  33, -36, -34, -30, -40,  10, -37, -24, -31, -34, -29, -28,  41, -29, -37,  25, -18,  14, -47, -38; D=-27;
/I:         I=-27; MI=-28; MD=-28; IM=-28; DM=-28;
/M: SY='H';  M= -25, -37, -19, -22, -37, -31,  55, -33, -21, -12, -25,  39, -34,  29, -24,   4,  43, -31, -55, -26; D=-27;
/I:         I=-27; DM=-28;
/M: SY='L';  M= -34, -36, -52, -44,  -8, -54, -36,   1, -46,  67,   4, -51, -52, -38, -42, -45, -31,  -7, -38, -21; D=-27;
/I:         I=-27; DM=-28;
/M: SY='R';  M= -12, -40, -30,  12,   9, -40, -29,   7,  -3,  13, -18, -29, -38, -20,  33,   9,  -7, -20, -39, -24; D=-27;
/I:         I=-27; DM=-28;
/M: SY='L';  M= -33, -36, -52, -44,  -9, -53, -37,   2, -45,  64,   3, -51, -51, -39, -42, -44, -29,  11, -40, -21; D=-27;
/I:         I=-27; DM=-28;
/M: SY='N';  M= -19, -31,  -5,   9, -38, -18,  30, -38, -13, -41, -30,  72, -30,   8, -20,  34,  18, -35, -53, -29;
/M: SY='F';  M= -22, -32,   4,  -4,  60,  -7, -19, -28, -23, -25, -26,  50, -36, -23, -28,  32, -14, -29, -28,  -7;
/M: SY='Q';  M= -19, -41, -14,  20, -45,  -1, -18, -40,  11, -41, -29,  22,  42,  57, -14,  27, -16, -38, -41, -32;
/M: SY='Y';  M= -16, -36, -20, -22, -24,  33, -16, -36, -17, -36, -27,  26, -32,  30,   1,  35,   8, -34, -28,  40;
/I:         I=-32; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='G';  M= -17, -37, -23, -20, -39,  47, -26, -38,  29, -24, -28, -13, -29,  22,  14,   0,  30, -33, -39, -31;
/M: SY='Y';  M= -11, -36, -33, -28,  28, -37,  25,  11, -27,  12, -10, -26, -37,  21, -27,   2,  11,   7, -21,  49;
/M: SY='L';  M= -27, -32, -47, -40,  -6, -49, -36,  25, -41,  60,   6, -45, -45, -35, -39, -38, -23,  30, -37, -18;
/M: SY='N';  M=   0, -33,  47,  24, -39, -23, -17, -35, -15, -24, -31,  54, -29, -14, -23,   7,  27, -31, -53, -33;
/M: SY='F';  M= -33, -34, -50, -44,  79, -48, -34,  18, -41,  33,  -4, -42, -47, -44, -39, -37, -27,   9, -15,   6;
/M: SY='T';  M= -19, -35, -23, -20, -33,  22, -27,  13,  18, -25, -20,  10, -29,  35, -19, -11,  43,   2, -42, -28;
/M: SY='F';  M= -38, -34, -51, -46, 100, -46, -31, -11, -42,   5, -12, -40, -49, -52, -39, -37, -30, -16,  -5,  17;
/M: SY='T';  M=  38, -28, -23, -23, -35,  15, -27, -25,  10, -28,  17,  20, -28, -21, -23,  -7,  39,  -9, -43, -31;
/M: SY='Q';  M= -23, -38, -31, -17, -27, -37, -24,  -9,  27,  12,  45, -26,  22,  48, -14, -24, -21,  23, -39, -23;
/M: SY='D';  M= -26, -39,  53,  32, -45, -26, -15, -44,  43, -44, -36,  50, -28,  -8,  -8, -16, -18, -41, -50, -33;
/I:         I=-32; MD=-33;
/M: SY='E';  M= -11, -57, -35,  29, -52, -25, -45, -48, -36,  -7, -41, -43, -49, -32, -14, -11, -17, -45, -62, -51; D=-32;
/I:         I=-32; MI=-33; IM=-33; DM=-33;
/M: SY='N';  M= -16, -34, -10,   1, -40,  24,  40, -42, -16, -42, -31,  59, -31,  16, -21,  40, -12, -39, -49, -28;
/M: SY='Q';  M= -17, -37, -15,  33, -36, -27, -18, -31,  14,   3, -22, -15, -28,  55, -12,  40, -15, -29, -39, -27;
/I:         I=-28; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='S';  M= -22, -40,   6, -23, -49, -26, -26, -48,  19, -51, -42,  36, -38, -19, -22,  50, -15, -43, -56, -40; D=-28;
/I:         I=-28; DM=-29;
/M: SY='H';  M=  -2, -44, -37, -31, -37, -44,  46, -27, -18,  -8, -25, -30, -44, -25,  43, -28,   8,   7, -54, -29; D=-28;
/I:         I=-28; DM=-29;
/M: SY='F';  M= -30, -36, -43, -39,  73, -45, -24,  -5, -29,  -8, -12, -37, -46, -36,  10, -32, -25,  30, -10,  52;
/M: SY='Y';  M= -35, -43, -36, -38,  51, -42,  -4, -18, -31, -13, -13, -36, -47, -28, -28, -31, -29, -23,   8, 102;
/M: SY='L';  M=   1, -32, -46, -39,  -8, -44, -34,  25, -39,  60,   5, -43, -44, -33, -38, -34, -23,  14, -36, -19;
/M: SY='K';  M= -18, -38,   9,  22, -43, -25, -17, -41,  47, -40, -30,   8, -26,  46,  -3,  35, -14, -37, -41, -29;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='E';  M=  18, -38,  -4,  70, -44,  20, -21, -44, -12, -39, -34, -19, -22,  -5, -21,   3, -21, -35, -42, -36;
/M: SY='V';  M= -17, -32, -48, -40, -15, -46, -50,  21, -38,  -4,  -7, -43, -42, -40, -39, -31, -16,  74,  65, -20;
/M: SY='N';  M=  -3, -38,  -7,  40, -44,  27, -16, -43,  -9, -42, -32,  54, -29,  29,  12, -13, -20, -40, -44, -34;
/M: SY='Y';  M=  19, -33, -41, -37,  -7, -39, -29,  32, -35,  32,  -3, -38, -40, -31, -36, -27, -21,  27, -26,  42;
/M: SY='N';  M=  -7,  28,  21, -20, -21, -20, -11, -34, -18, -36, -29,  64, -35, -17, -24,  24,   5, -32, -33,  44;
/M: SY='M';  M= -24, -32, -44, -37, -12, -44, -30,  22, -34,  38,  73, -36, -38, -30, -34, -30,  11,  27, -39, -18;
/I:         I=-28; MD=-29;
/M: SY='T';  M= -24, -38, -34, -36, -20, -38, -29, -10, -32, -28, -26, -25, -38, -31, -36,  22,  49,   4, -34,  45; D=-28;
/I:         I=-28; MD=-29;
/M: SY='F';  M= -37, -41, -56, -50,  51, -55, -41,  12, -48,  37,  12, -50, -53, -47, -46, -45, -33,  14, -31, -11; D=-28;
/I:         I=-28; MD=-29;
/M: SY='P';  M= -37, -62, -45, -40, -64,   2, -49, -58, -44, -65, -53, -41,  69, -43, -53,  19, -34, -58, -61, -59; D=-28;
/I:         I=-28; MI=-29; MD=-29; IM=-29; DM=-29;
/M: SY='D';  M= -40, -55,  58, -16, -61, -39,  22, -60, -30, -58, -50,  13, -45,  20, -35,   3, -32, -57, -72, -42; D=-28;
/I:         I=-28; DM=-29;
/M: SY='A';  M=  50, -29, -32, -26, -32, -22, -34,  11, -27, -23, -19, -26,  29, -25, -33,  13,  10,  16, -42, -32;
/I:         I=-32; MD=-33;
/M: SY='N';  M=  14, -39, -20, -29, -46, -26, -24, -42,  -8, -28, -36,  63, -43, -23,   6,   9, -21, -39, -57, -41; D=-32;
/I:         I=-32; MI=-33; IM=-33; DM=-33;
/M: SY='G';  M= -19, -40,  15,  35, -44,  48, -21, -36, -16, -38, -31,  21, -29,  39, -23, -15, -24,  -7, -43, -34;
/M: SY='W';  M= -16, -35, -28, -24, -28, -10, -33, -25,   2, -32, -28, -19,  30, -21, -26,  43,  30,   2,  88, -21;
/M: SY='T';  M=  37, -27, -30, -27, -28, -25, -35,  16, -27, -19, -17, -21, -29, -26, -32,  18,  44,  23, -44, -29;
/M: SY='F';  M= -35, -36, -45, -43,  90, -43, -23, -13, -38,   1, -13, -37, -47, -42, -35, -13, -28, -18,  -3,  55;
/M: SY='S';  M=   2, -33, -16,  14, -37, -21,   9, -32,  -3, -30,  27,  11, -28,  44, -17,  50,   2, -29, -43, -26;
/M: SY='A';  M=  36, -33, -30,  -4, -29,  26, -36,  35, -29, -18, -17, -24, -31, -26, -35,   1,   0,   8, -40, -30;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='Q';  M=  19, -38, -29, -19, -36, -29,  21,  16, -22, -24,  16, -21, -34,  53, -23,  23,  -5, -19, -43, -26; D=-30;
/I:         I=-30; DM=-32;
/M: SY='N';  M= -26, -33,  26, -13, -41, -18,  -9, -41,  30, -46, -33,  87, -34, -11, -12, -10, -12, -41, -54, -34;
/M: SY='H';  M=  -1, -35, -15, -16, -29,  -7,  55, -37,   3, -36, -26,  42, -32,  34, -16,  35, -14, -35, -37,  24;
/M: SY='N';  M=  12, -27, -13, -21, -36, -16, -19, -32, -18, -37, -30,  55, -28, -16, -24,  48,  40, -26, -50, -31;
/M: SY='L';  M= -28, -32, -47, -39,  -5, -48, -32,   7, -40,  65,  34, -45, -46, -33, -37, -39, -24,  19, -36, -17;
/M: SY='R';  M= -17, -33, -23, -19, -33, -27, -21, -23,   4, -27,  20,  10, -32,   9,  46,  39,  15,   7, -44, -26;
/M: SY='M';  M=  26, -32,   5,  11,  27, -30, -21, -19, -24, -15,  51, -23, -32, -21, -28, -16,  22, -18, -25,  35;
/I:         I=-16; MI=0; MD=-17; IM=0; DM=-17;
/M: SY='W';  M= -32, -39, -53, -42,  43, -44, -39,  -5, -38,  37,  23, -47, -45, -37, -38, -40, -31,   8, 112,   0;
/M: SY='Q';  M= -23, -44,  40,  35, -49, -31, -14, -40,  -7, -36, -27, -10, -27,  81, -11, -13,  11, -38, -43, -28;
/M: SY='A';  M=  66, -24, -28, -23, -37, -16, -32, -26, -24, -29, -24, -21, -27, -23, -30,  -3,  40, -15, -41, -33;
/M: SY='P';  M=  -3, -35, -25, -23, -36, -28, -31, -20, -24, -31, -25,   7,  71, -26, -32,  13,  44,  11, -47, -34;
/M: SY='V';  M=  12, -31, -41, -31, -16, -39, -34,   5, -32,  37,   8, -37, -40,  17, -32, -26, -19,  48, -41, -22;
/M: SY='G';  M= -14, -38,   1, -32, -43,  78,  20, -49, -30, -45, -35, -11, -30, -27, -36, -12,   8, -43, -41, -35;
/M: SY='H';  M= -18, -35, -11, -13, -39, -20,  61, -40,   5, -39, -27,  54, -31,  40, -14,  40, -12, -38, -50, -22;
/M: SY='S';  M=  14, -27, -20, -20, -37, -12, -23, -36, -20, -39, -33,  -9, -27, -12, -25,  79,   0, -28, -45, -30;
/M: SY='Y';  M= -36, -40, -40, -40,  72, -43, -10, -16, -34, -10, -13, -37, -48, -34, -31, -32, -29, -21,   5,  91;
/M: SY='M';  M= -23,  46, -28, -17, -31, -34, -21, -24,  57, -19,  67, -18, -31, -11,  15,  -1, -20, -24, -39, -24;
/M: SY='C';  M= -48, 277, -88, -88, -69, -80, -88, -83, -80, -64, -64, -61,-110, -95, -93, -54, -48, -58,-129, -90;
/I:         I=-32; MD=-33;
/M: SY='N';  M= -29, -40, -19, -31, -40, -30,  37, -27, -24, -38, -31,  64, -44, -24,  -8,   7, -20,  16, -63, -34; D=-32;
/I:         I=-32; MI=-33; IM=-33; DM=-33;
/M: SY='S';  M=   4, -31, -20, -17, -38,  12, -25, -36,  41, -38, -30, -10, -26, -13, -11,  46,  31, -28, -42, -30;
/M: SY='E';  M=   4, -39,   2,  74, -44, -30, -16, -44,   9, -40, -34,  35, -22,  -1, -14, -16, -20, -37, -45, -36;
/M: SY='Q';  M=  -4, -42, -15,  25, -48, -29, -14, -38,  17, -35, -24, -13, -27,  86,  -5,   6,  -3, -36, -37, -27;
/M: SY='S';  M= -15, -32, -24, -20, -29, -27,  42, -20, -18,  -1, -19, -15, -31,  24,   9,  45,  23,  10, -46, -22;
/M: SY='I';  M= -24, -36, -46, -43, -12,   0, -41,  56, -40,  36,   0, -38, -40, -37, -42, -33, -22,  31, -38, -21;
/M: SY='Q';  M= -20, -37, -27, -15,  11, -32, -22,   2,  13,   1, -16, -20, -34,  57,  11,  26, -17,   7, -35, -19;
/M: SY='V';  M= -21, -31, -47, -40, -11, -48, -42,  23, -39,  39,   1, -43, -44, -38, -39, -33, -18,  61, -44, -21;
/M: SY='S';  M=  -7, -27, -20, -22, -36,  13, -25, -34, -21, -38, -32,  -8, -26, -16, -26,  70,  38, -27, -46, -30;
/M: SY='P';  M=  20, -40,   7,  22, -44,  23, -25, -41,  17, -41, -32, -18,  42, -14,  22,  -4, -22, -35, -41, -35;
/M: SY='H';  M=  41, -32,  18,  -1, -38, -21,  42, -33, -17, -31,   6, -15, -29,  17,   4,  20,   7, -25, -45, -25;
/I:         I=-32; MD=-33;
/M: SY='F';  M= -35, -37, -53, -47,  67, -52, -38,   7, -45,  36,  -7, -47, -51, -47, -43, -42, -30,  15, -23,  -2; D=-32;
/I:         I=-32; MI=-33; IM=-33; DM=-33;
/M: SY='Q';  M=  -7, -37, -21, -11,  -3, -28,  56, -30, -14, -29, -21, -13, -30,  67, -15,  22,  25, -12, -41, -17;
/M: SY='I';  M= -26, -35, -48, -42,  -9, -50, -39,  54, -40,  43,  32, -42, -41, -35, -40, -37, -22,  29, -38, -18;
/M: SY='N';  M= -27, -35,  51,  -9, -43, -20, -11, -42,  29, -46, -35,  78, -32, -12, -12, -12, -14, -42, -55, -33;
/M: SY='T';  M=  -4, -28, -31, -31, -20, -36, -34,  22, -28,  17,  11, -22, -31, -28, -33,   2,  59,  19, -44, -24;
/M: SY='F';  M= -31, -34, -40, -35,  74, -42, -26, -11,   4,  19,  26, -32, -41, -34, -27, -29,  14, -15, -15,  26;
/M: SY='N';  M= -19, -34,  44, -11, -40, -21,  25, -39,  -2, -41, -33,  52, -30,   7,  -3,  35,  16, -36, -53, -29;
/M: SY='V';  M= -20, -31, -43, -38, -12, -43, -38,  22, -37,  43,   0, -39, -42, -34, -37,   2, -17,  49, -42, -21;
/M: SY='R';  M= -28, -45, -20, -10, -38, -33,  30, -42,  26, -37, -26,  20, -34,  55,  59, -19, -26, -41,  54, -20;
/M: SY='V';  M= -20, -30, -47, -40, -11, -48, -41,  14, -39,  42,   1, -44, -44, -38, -39, -33, -18,  62, -44, -21;
/M: SY='Q';  M= -23, -47, -19,   0, -47, -32, -13,   2,  -5, -28, -18, -15, -30, 101,  -6, -13, -25, -30, -35, -23;
/M: SY='A';  M=  63, -30, -31, -22, -38, -17, -33, -28, -26, -16, -24, -29,  56, -24, -32, -10, -17, -19, -39, -36;
/M: SY='F';  M=  12, -33, -47, -42,  94, -38, -31, -14, -39,  -7, -15, -37, -45, -46, -37, -30, -27, -17,  -8,  13;
/M: SY='N';  M=   3, -38,  38,  -9, -44,  11, -15, -42,  18, -42, -31,  50, -32,  40,  13, -13, -19, -39, -46, -32;
/M: SY='V';  M= -23, -32, -43, -34,  40, -45, -36,   7, -34,  27,  -4, -39, -43,  16, -34, -31, -20,  53, -33, -11;
/I:         I=-32; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='D';  M= -24, -37,  52,  42, -38, -32,  26, -34,   1, -31,  26,  11, -26, -11, -19, -15,  31, -31, -51, -28;
/M: SY='N';  M= -19, -36,  24, -14, -43,  36, -19, -42,  33, -43, -33,  42, -30,  16, -13,   9,   5, -39, -44, -33;
/M: SY='G';  M= -19, -41,  58,   2, -47,  64, -24, -51, -24, -48, -41,  15, -30, -22, -32, -14, -25, -46, -47, -38;
/M: SY='H';  M= -22, -37, -19,  -2, -35, -32,  65, -31,  36, -31, -23, -12, -28,  24,  17,   6,  31,  -7, -46, -20;
/M: SY='F';  M= -35, -36, -47, -44,  89, -45, -24,  -9, -39,  -6, -13, -39, -48, -44, -36, -35, -28,   7,  -3,  56;
/M: SY='G';  M=  15, -34, -29, -34,  14,  64, -31, -36, -31, -15, -28, -17, -32, -27, -36,  23, -22, -31, -33, -26;
/M: SY='P';  M= -20, -36, -21, -20, -37, -27, -26,  -2, -21, -33, -26,  24,  68,  11, -29,  16,  45, -23, -46, -33;
/M: SY='C';  M=  44,  47, -34, -30, -29, -26, -37,  -7, -30, -19, -18, -27, -34, -29, -34,   6,  15,  41, -47, -31;
/M: SY='Q';  M= -27, -42,  51,  41,  31, -35, -18, -31, -14, -29, -27, -14, -30,  52, -19, -20, -23, -10, -36, -18;
/M: SY='E';  M= -20, -41,  39,  65, -46, -30, -16, -45,  -8, -40, -35, -12, -23,  39, -16,  23, -18, -39, -46, -33;
/I:         I=-28; MI=0; MD=-29; IM=0; DM=-29;
/M: SY='C';  M= -48, 277, -88, -88, -69, -80, -88, -83, -80, -64, -64, -61,-110, -95, -93, -54, -48, -58,-129, -90;
/M: SY='S';  M=  -3, -33, -25, -23,   4, -23, -20, -21, -23,   2,   7,   7,  11,  16, -26,  50, -11,  -9, -31,  24;
/M: SY='S';  M=  19, -31, -31, -24, -22, -26, -25, -15, -23,  36, -10, -24, -35,  17,   0,  39, -14, -16, -38, -24;
/M: SY='D';  M= -31, -44,  99,   6, -51, -27, -16, -49, -18, -48, -47,   2, -30, -17, -26, -19, -20, -46, -66, -34;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='E';  M= -47, -67,  28,  37, -69,  -8, -41, -71, -29, -65, -60, -35, -48, -29,   7, -42, -47, -65, -69, -57; D=-30;
/I:         I=-30; DM=-32;
/M: SY='N';  M= -27, -39,  46, -10, -23, -27, -10, -35, -12, -35, -28,  50, -34,  36,   7, -14,  12, -35, -32,  45;
/M: SY='N';  M= -14, -28, -11, -22, -37,   4, -18, -34, -17, -39, -31,  61, -29, -16, -24,  45,  43, -29, -51, -32;
/M: SY='M';  M= -27, -36, -39,   4,  38, -46, -31,  44, -33,  16,  64, -36, -37, -29, -34, -34, -23,  14, -30, -10;
/M: SY='L';  M= -24, -31, -47, -40,  -8, -49, -37,  19, -40,  56,   4, -45, -45, -36, -39, -36, -21,  44, -39, -19;
/M: SY='I';  M= -24, -34, -48, -42, -10, -50, -42,  49, -40,  40,   2, -43, -42, -37, -41, -35, -20,  46, -40, -20;
/M: SY='P';  M= -29, -55, -30, -18, -49, -31, -33, -37, -26, -47, -33, -36, 112, -30, -39, -27, -22, -42, -42, -46;
/I:         I=-32; MD=-33;
/M: SY='I';  M= -38, -48, -58, -55, -19, -62, -54,  67, -51,  20,  -6, -50, -48, -47, -53, -47, -32,   6, -45, -28; D=-32;
/I:         I=-32; MI=-33; IM=-33; DM=-33;
/M: SY='V';  M=  36, -30, -41, -35, -21, -34, -43,  40, -35,  -7,  -8, -35, -37, -33, -38, -21, -16,  53, -43, -26;
/M: SY='V';  M= -18, -32, -47, -42, -16, -49, -49,  49, -39,   0,  -3, -41, -41, -40, -41, -31, -16,  69, -47, -23;
/M: SY='G';  M= -12, -40, -27, -39, -46,  87, -34, -54, -33, -49, -38, -13, -31, -30, -40, -12, -31, -47, -37, -41;
/M: SY='A';  M=  55, -29, -34, -30, -29,  29, -34,   2, -30,  12, -16, -26, -33, -26, -34, -12, -20, -13, -37, -31;
/M: SY='A';  M=  49,  44, -37, -33, -28,   3, -39,  35, -32, -16, -15, -29, -35, -30, -37, -15, -18,  16, -41, -30;
/M: SY='L';  M= -27, -31, -47, -40,  -6, -49, -34,   8, -40,  65,   6, -46, -46, -35, -38, -38, -24,  29, -37, -18;
/M: SY='A';  M=  49, -28, -34, -30, -27,  12, -34, -11, -30,  13, -14, -28, -34, -27, -33,   7, -16,  24, -40, -29;
/M: SY='G';  M=   9, -37, -30, -37, -40,  77, -35, -33, -33, -38, -31, -17, -32, -31, -39, -13, -27,   5, -39, -38;
/M: SY='L';  M= -28, -32, -47, -40,  -5, -49, -33,   7, -41,  67,   7, -46, -47, -35, -38, -39, -24,  20, -36, -17;
/M: SY='C';  M= -23,  69, -47, -42, -14, -47, -42,  34, -40,  33,  -3, -40, -45, -39, -41, -33, -20,  44, -45, -24;
/M: SY='L';  M=   5, -31, -42, -37, -13, -42, -38,  31, -36,  39,  -1, -37, -39, -34, -38, -26,  14,  38, -41, -22;
/M: SY='I';  M= -24, -33, -47, -42, -10, -49, -40,  46, -40,  39,  25, -42, -42, -36, -40, -35, -20,  45, -40, -20;
/M: SY='V';  M= -16, -32, -42, -41, -20,  23, -46,  29, -37,  -7,  -9, -34, -39, -38, -40, -26, -17,  66, -46, -27;
/M: SY='L';  M= -27, -32, -47, -39,  -6, -47, -30,   6, -38,  61,  53, -44, -44, -32, -36, -38, -24,  20, -36, -17;
/M: SY='I';  M= -23, -37, -43, -43, -16,  22, -41,  58, -39,  20,  17, -34, -38, -36, -42, -30, -23,  27, -38, -23;
/M: SY='A';  M=  64, -27, -33, -27, -34,  12, -35,   4, -29, -24, -20, -26, -31, -26, -33,  -9, -17,  14, -40, -33;
/M: SY='Y';  M= -35, -43, -36, -38,  48, -42,  -4, -18, -30, -14, -13, -36, -47, -27, -27, -30, -29, -23,   8, 103;
/M: SY='C';  M= -29,  65, -40, -32,  37, -43, -31,  -9,  22,  42,  -6, -34, -44, -30, -24, -33, -25,  -3, -31, -13;
/M: SY='I';  M= -26, -40, -49, -47, -12, -53, -49,  80, -42,   4,   1, -39, -38, -39, -45, -36, -20,  32, -38, -20;
/M: SY='G';  M= -16, -39, -28, -32, -40,  70, -30, -11, -19, -38, -30, -15, -32, -24,  30, -14,  10, -33, -38, -35;
/M: SY='R';  M= -30, -43, -30, -17, -28, -41, -18, -27,   4,  19, -15, -24, -40,  20,  80, -26, -28, -28, -37, -23;
/M: SY='R';  M=   1, -41, -23, -11, -40, -34, -19, -42,  54, -38, -27, -16, -33,  -4,  72, -20, -24, -36, -37, -27;
/M: SY='R';  M= -29,  49, -26, -15, -39, -39,   9, -45,  35, -38, -28, -18, -37,  -6,  80, -24, -27, -38, -41, -27;
/M: SY='Q';  M=   7, -37, -20, -11, -42,  -3,  45, -38, -15, -36, -25, -12,  13,  63, -16,  40,  -1, -34, -42, -24;
/M: SY='H';  M= -18, -36, -19, -18, -24, -24,  87, -39,  10, -33, -23, -10, -31, -11, -16,  49, -14, -36, -38,  34;
/M: SY='A';  M=  47, -27, -25, -21, -37, -17, -27, -31, -18, -33, -27, -16, -28, -17,  13,  41,  33, -20, -43, -31;
/I:         I=-30; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='G';  M=   0, -46, -36, -45, -53,  76, -42, -59, -40, -55, -45, -22, -39, -37, -47, -19, -37, -51, -45, -48; D=-30;
/I:         I=-30; DM=-32;
/M: SY='Y';  M= -34, -45, -34, -37,  18, -41,   0, -20, -28, -16, -13, -35, -46, -24, -25, -29, -29, -25,  10, 110;
/M: SY='Q';  M=   4, -44, -13,  34, -50, -29, -13, -39,  -5, -34, -23, -15, -27,  93,  -7, -12, -24, -37, -37, -27;
/M: SY='T';  M=  -1, -34, -22, -15, -38, -29, -23, -31,  -9, -33, -25, -15,  26,  40,  34,  14,  53, -26, -43, -29;
/M: SY='I';  M= -28, -36, -49, -44,  29, -50, -39,  57, -41,  36,  24, -41, -41, -38, -41, -37, -23,  22, -31, -12;
/I:         E1=0; IE=-105; DE=-105;
» more

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2024_02 which contains 571'282 sequence entries.


Total number of hits 18 in 18 different sequences
Number of true positive hits 18 in 18 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] PS_Langendijk_Genevaux
Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
18 sequences

CD68_HUMAN  (P34810), CD68_MOUSE  (P31996), LAMP1_BOVIN (Q05204), 
LAMP1_CHICK (P05300), LAMP1_CRIGR (P49129), LAMP1_HUMAN (P11279), 
LAMP1_MOUSE (P11438), LAMP1_RAT   (P14562), LAMP2_CHICK (Q90617), 
LAMP2_CRIGR (P49130), LAMP2_HUMAN (P13473), LAMP2_MOUSE (P17047), 
LAMP2_RAT   (P17046), LAMP3_HUMAN (Q9UQV4), LAMP3_MACMU (Q8MJJ2), 
LAMP3_MOUSE (Q7TST5), LAMP3_RAT   (Q5XI99), LMP1_CAEEL  (Q11117)
» more

PDB
[Detailed view]
8 PDB

2MOF; 2MOM; 4AKM; 5GV0; 5GV3; 8ATH; 8FY5; 8FYF