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PROSITE entry PS51352


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51352
Entry name [info] THIOREDOXIN_2
Accession [info] PS51352
Entry type [info] MATRIX
Date [info] 01-DEC-2007 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00172
Associated ProRule [info] PRU00691

Name and characterization of the entry

Description [info] Thioredoxin domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=137;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=137;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-1.8272276; R2=0.0066185; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=16355.6416016; R2=3.6087751; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1561; H_SCORE=21989; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1259; H_SCORE=20899; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-15; D=-100; I=-100; B1=-300; E1=-300; MI=-150; MD=-150; IM=-150; DM=-150;
...
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Post-processing [info]

COMPETES_HIT_WITH PS50404; PS51353; PS51354; PS51355

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 981 in 873 different sequences
Number of true positive hits 980 in 872 different sequences
Number of 'unknown' hits 1
Number of false positive hits 0
Number of false negative sequences 72
Number of 'partial' sequences 5
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 93.16 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 3
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] Thioredoxin
Version [info] 8

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
872 sequences

1CPX_DIRIM  (O17433), 1CPX_ONCVO  (P52570), AHP1_CHATD  (G0S1P8), 
» more

UniProtKB/Swiss-Prot
False negative sequences
72 sequences

APRL5_ARATH (Q93YX4), APRL6_ARATH (Q9ZPE9), APRL7_ARATH (Q84JN1), 
» more

UniProtKB/Swiss-Prot
'Partial' sequences
5 sequences

PDIA3_MESAU (P86235), PRDX4_CROAT (P0CV91), PRDX5_MESAU (P86241), 
» more

UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

SCO1_MOUSE  (Q5SUC9)

		
PDB
[Detailed view]
746 PDB

1A23; 1A24; 1A2J; 1A2L; 1A2M; 1AC1; 1ACV; 1AIU; 1AUC; 1BED; 1BQ7; 1CQG;
» more