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PROSITE entry PS51285


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51285
Entry name [info] AGC_KINASE_CTER
Accession [info] PS51285
Entry type [info] MATRIX
Date [info] 01-DEC-2006 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51285
Associated ProRule [info] PRU00618

Name and characterization of the entry

Description [info] AGC-kinase C-terminal domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=72;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=67;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.9194913; R2=0.0163582; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3483.5212402; R2=3.2733018; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=384; H_SCORE=4740; N_SCORE=8.2; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=281; H_SCORE=4403; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-7; D=-20; I=-20; B1=-200; E1=-200; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 346 in 346 different sequences
Number of true positive hits 346 in 346 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.19 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] AGC-kinase C-terminal
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
346 sequences

AKT1_BOVIN  (Q01314), AKT1_CAEEL  (Q17941), AKT1_DROME  (Q8INB9), 
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UniProtKB/Swiss-Prot
False negative sequences
10 sequences

AGC15_ARATH (Q9LTW5), AGC17_ARATH (Q1PFB9), IRE4_ARATH  (F4HPN2), 
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PDB
[Detailed view]
613 PDB

1APM; 1ATP; 1BKX; 1BX6; 1CDK; 1CMK; 1CTP; 1FMO; 1FOT; 1GZK; 1GZN; 1GZO;
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