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PROSITE entry PS51232


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51232
Entry name [info] GBD_FH3
Accession [info] PS51232
Entry type [info] MATRIX
Date [info] 01-AUG-2006 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51232
Associated ProRule [info] PRU00579

Name and characterization of the entry

Description [info] Rho GTPase-binding/formin homology 3 (GBD/FH3) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=372;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=367;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.3135400; R2=0.0029745; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=111127.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=2753; H_SCORE=111127; N_SCORE=10.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1408; H_SCORE=111127; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-14; D=-160; I=-160; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 51 in 51 different sequences
Number of true positive hits 51 in 51 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 98.08 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] GBD/FH3
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
51 sequences

BNI1_CANAL  (Q5AL52), BNI1_YEAST  (P41832), BNR1_CANAL  (Q5AAF4), 
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UniProtKB/Swiss-Prot
False negative sequences
1 sequence

RID1_SCHPO  (O74737)

		
PDB
[Detailed view]
15 PDB

1Z2C; 2BAP; 2BNX; 2F31; 3DAD; 3EG5; 3O4X; 3OBV; 4UWX; 4YC7; 4YDH; 6XF1;
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