PROSITE entry PS51204
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General information about the entry
| Entry name [info] | HSA |
| Accession [info] | PS51204 |
| Entry type [info] | MATRIX |
| Date [info] |
01-MAY-2006 CREATED;
10-MAY-2017 DATA UPDATE; 27-MAR-2024 INFO UPDATE. |
| PROSITE Doc. [info] | PDOC51204 |
| Associated ProRule [info] | PRU00549 |
Name and characterization of the entry
| Description [info] | HSA domain profile. |
| Matrix / Profile [info] |
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=74; /DISJOINT: DEFINITION=PROTECT; N1=6; N2=69; /NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6783061; R2=0.0056114; TEXT='NScore'; /NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=11842.0527344; R2=3.2533453; PRIORITY=1; TEXT='Heuristic 5.0%'; /CUT_OFF: LEVEL=0; SCORE=1216; H_SCORE=15798; N_SCORE=9.5; MODE=1; TEXT='!'; /CUT_OFF: LEVEL=-1; SCORE=682; H_SCORE=14061; N_SCORE=6.5; MODE=1; TEXT='?'; /DEFAULT: M0=-46; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255; ... A C D E F G H I K L M N P Q R S T V W Y /I: B1=0; BI=-255; BD=-255; /M: SY='Q'; M=-133, -17, -60, -41, 4, -72,-125, 25, 15, 38, -4, -55, 48, 71, 4, -66,-130,-112,-141, -11; /M: SY='K'; M= -79, -24, -25, 38, -29, -62, 12, -40, 64, -26,-127,-121, 46, 40, 19, -24, -46, -43,-157, -43; /M: SY='R'; M= -10,-144, -9, -8, -10,-148, -18, -14, 38, -3, 23, -19, 15, 20, 51, -44, 5, -20,-144, -1; /M: SY='E'; M= -6, 23, 9, 58, -3, -85, -31, 1, -25, -9, -2,-127, 32, 47, -67, -22, -19, -10,-150, -45; /M: SY='Q'; M= -2,-148, -13, 38, -58, -82, 26, -60, -12, -64, -46, -50, 42, 65, 31, 6, -78, -6, 0, 9; /M: SY='E'; M= -33,-155, -54, 82,-156, -14,-125,-133, 4, -7, -25, -26, 29, 10, 17, -35, -15, -16,-166,-158; /M: SY='P'; M= -10, -21, -53, 35,-150, -86,-127,-128, 10, -26, 24, 14, 69, 9, 41, -13,-123, 0, 27,-150; /M: SY='P'; M= -21,-147, -26, 27, -59, -31, -35, -47, 34, -63,-131, 3, 49, 44, 36, 10, 0, -27,-155, -36; /M: SY='R'; M= -52,-155, -26, 14,-156, -79,-116, 9, 18, -88,-128, -6, 6, 40, 89, -14, -54, -49,-156,-151; /M: SY='P'; M=-129,-157, -43, 16, -55,-149, 37, -56, 37, -44,-131, 9, 59, 48, 58, -29, -39, -48,-151, -13; /M: SY='K'; M= -23,-149, -47, -3, -35, -60, 24, -10, 72,-143,-129, 22, -31, 54, 19, -22, -56, -43, 43, -24; /M: SY='T'; M= -4,-130, -44,-122, -12, -85,-129, -42, 49, -63,-125, -55,-143, -43, 30, 47, 69, -9,-154,-138; /M: SY='H'; M=-139,-164,-125, 10, 12,-156, 133,-152, -1, -44,-134,-110,-153, 48, -29,-127, -26,-150,-138, 12; /M: SY='W'; M= -51, -40,-139,-123,-128, -74, 42, -45, -18, -27,-122, -2,-155, 68, 57, -68, -8, -55, 132,-109; /M: SY='D'; M= -79,-163, 101, 37, -51, -26,-122,-158, -61, -88,-153, 28,-151, 22, -48, -60, -28, -57,-158, 3; /M: SY='H'; M= -35,-144, -62, -19, 49, -76, 87, -37, 9, -11,-122, -46,-161, 4,-127, -64, -57, -7,-108, 87; /M: SY='L'; M=-137,-135,-156, -9, 12,-170, 1, -4, -40, 73, 48,-154,-164, -50, -8,-144, -30, 20,-142,-124; /M: SY='L'; M= -33, -9, -59, -65, -31, -74,-142, 25,-143, 70, -8, 9, -46, 23, -61, -23, -34, -1,-149,-135; /M: SY='Q'; M= 12,-146, 9, 62, -35, -80, -34,-154, 41, -84,-135, 1,-140, 69, -55, 24, -22,-142,-158,-145; /M: SY='E'; M= -10,-148,-101, 87,-148, -53, 53, 40, -28,-132,-127, -57,-147, 19, -59, -9, -55, -22,-164, -53; /M: SY='M'; M= 10, 21,-159, -61, -48, 15,-151, 38,-145, 7, 110, -78,-156,-133, -64, -53, -59, 7,-139, -58; /M: SY='Q'; M= 6, -25,-120, -4,-138,-142, -21, -3, 48, 19, 24, 50,-148, 52, -28, -61, 6, -31,-155,-144; /I: I=-17; MD=-42; /M: SY='W'; M= -54,-154,-136, 9, -52, -48, 11,-155, -8,-159,-142, 26,-168,-130,-141, 10, -40, -30, 142, -6; D=-17; /I: I=-17; MI=0; MD=-42; IM=0; DM=-42; /M: SY='M'; M= -74,-137,-152,-143, 55,-159, 94, -21,-141, 3, 106, -57,-158, -52, -62, 2, -50, -47,-124, -9; /M: SY='S'; M= 51, -31,-132,-121,-145, 4,-123, -20, 5,-143,-134,-119,-139, 30, 50, 58, -53, -70,-148, -11; /M: SY='K'; M= 21,-141, 22, 26,-155, -60,-127, -1, 64,-140,-130, 16,-144, -23, 16, -38, 25, -8,-166,-151; /M: SY='D'; M=-135, -16, 92, 38,-146, -51, -22,-136, -23, 18, -37, -7,-152, -23, -2, -12, -59, -76,-164, -36; /M: SY='F'; M= -68,-133,-166,-160, 101,-168, -7, -4,-146, 2, 44,-153,-169, -50, -2, -34, -37, 5, -1, 20; /M: SY='Q'; M= 11,-143, -12, -2, -10,-146, 17, -11, 24, -30, 19, -29,-148, 56, 50, -12,-122, -19,-134, 35; /M: SY='E'; M= -24,-154, 47, 74,-154,-141,-113, -63, -23,-156,-139, 35,-144, 68, -18, -20, -2, -80,-156, -10; /M: SY='E'; M= -12,-151, -28, 84, 15, -29, -27,-140, -10, -45, -8, -13,-148, -39, 11, 2, -76, -45,-140, 34; /M: SY='H'; M= -9,-153, -59, -66, -4, -86, 87, -55, 25, -58,-131, -61,-149, 20, 82, -24, -16, -47,-146, -41; /M: SY='K'; M= -70,-151, -56,-115, -58, -52, -38, -69, 76, -36, -30, -1,-147, 9, 71, -6, -36, -15, 15,-142; /M: SY='W'; M= -28,-143, -16, -30, 2, -78, -32, -80, 3, -59,-128, 12,-156, 28, 21, 20, -14, -17, 128, 34; /M: SY='K'; M= -80,-158, -55,-110, -49, -52, 67, -39, 89,-147, -39, 11,-145, 30, 44,-123,-126, -48,-162,-132; /M: SY='R'; M= -28,-141,-135, -37,-141,-148, -5, 30, 45, -22, 38, -27,-149, 25, 66, 9, -23, -11,-154,-143; /M: SY='A'; M= 51,-134, 17, 4, -48, -16, 7, -28, 20, -25,-129, 38,-143, 2, -27, -9, 9, -70, -7, -16; /M: SY='R'; M= 32, 0,-134, -62,-146, -71, 4, -11, 43, -55, 19, -4,-145, 32, 56, -25, -22, 18,-153,-144; /M: SY='A'; M= 69, 63,-145, -56, 7,-132, -25, 5, -63, 0, 21,-135,-142, -26, 1, 5, 2,-110,-145,-130; /M: SY='K'; M= -9, -35,-130, -59, -36, -75, 16, -41, 78, -84,-128,-117,-144, 27, 56, -11, 13, -30,-152, -21; /M: SY='K'; M= -29,-150,-125, -14, -49, -32, -36, -78, 74, -65,-128, -22,-145, 45, 60, -23, -1, -11,-155, -44; /M: SY='M'; M= -59, 23,-171,-165, 54,-172,-152, 44,-153, 51, 58, -49,-168,-147, -32, -86,-128, 32,-133,-109; /M: SY='A'; M= 69, 37,-132,-132,-151, 27,-137,-132, -80,-142, -26, 10,-139,-127, -17, 45, -5, -10, 2,-148; /M: SY='H'; M= -22,-155, -26, -31, -61, -45, 66, -43, 41, -90,-132, 22,-148, 66, 63, -52, -52,-144,-142, 19; /M: SY='M'; M= 57, -14, -57, -22,-128, -36, 18, -30, -21, -25, 71, -43,-143, -19, 17, 12, -46,-118, 70, 0; /M: SY='C'; M= -6, 91,-171,-161,-126, -83,-164, 57,-158, -26, 61,-157,-163,-150,-161, -58,-118, 65,-150,-143; /M: SY='M'; M= 40,-131, -30, 17,-132, -73,-127, 17, -11, -3, 61, 26,-146, 29, -13, -7, -21, -17, -26, -19; /M: SY='Q'; M= 8,-144, 27, 33,-157,-136,-116,-148, 29, -37,-131, 40,-143, 63, 22, -1, 32,-138,-159,-151; /M: SY='H'; M= -22,-143,-142, -20, 42, -59, 94, -58,-145, -12,-126, -43,-163, -35,-138, -27, -14, -48, 65, 91; /M: SY='H'; M=-143, -17,-150,-143, 44, -43, 123, -5,-149, -6, -39,-126,-164,-118,-133, -55,-136, -18, 107, -22; /M: SY='Q'; M= 9, -43,-121, 14, -32, -52, 9, -29, 40, -32,-124, 9,-145, 46, 29, 12, 31, -31,-149, -17; /M: SY='N'; M= -17,-148, 15, 24, -59, -73, 55,-147, 1, -38,-136, 65,-151, 31, 35, -15, -12, -77,-140, 37; /M: SY='K'; M= -72,-140, -11, -55,-137, -1,-128, 12, 46, 8, 15, -43,-151, 25, 39, -17, 41, -16,-153, -36; /M: SY='E'; M= 10,-153, -31, 82, -21,-142, -22,-150, 36, -87, -32, 23, 14, 29, -24, -57, -63, -65,-163,-145; /M: SY='K'; M= -39,-153,-125, 15,-156, 12,-125, -24, 68, -56,-128,-121, 3, 14, 61, -70, -8, -10,-163,-154; /M: SY='E'; M= 11, 41, 21, 77,-156,-143, -16, -32, 11, -37, -5, -4,-145, 12, 12, -14, -60,-133,-165,-152; /M: SY='E'; M= -41, 48, 12, 79,-159,-149, 25, -43, 28, -50,-136,-118, 7, 20, 24, -37, -59, -83,-167,-150; /M: SY='Q'; M= -38, -35, -50, 60,-154,-146,-113, -11, 42, -41,-123, -14,-143, 86, 8, 0,-120, -27,-157,-150; /M: SY='K'; M= -53, -31, -2, -7,-144,-146,-119, -62, 75, -36, 20, -15,-147, 8, 71,-122, -10, -75,-153, -11; /I: I=-18; MD=-45; /M: SY='R'; M= -29, 2, -26, 9, -10,-161, 4, -34, 17, -10,-131,-134,-161, 12, 68, -76, -61, -65, 14,-140; D=-18; /I: I=-18; MI=0; MD=-45; IM=0; DM=-45; /M: SY='I'; M= 1,-138, -67, 22,-137, -24,-137, 50, 41, 5, -6, -35, 14, -23, 17, -60, -48, 3,-161,-148; /M: SY='E'; M= 21,-149, -12, 88, -50,-142, -36, -18, 20, -47, -25,-120, -66, 22, -31, -1, -61, -78,-164,-149; /M: SY='R'; M= -53,-158, -52, 18, -51, -75, -4, -45, 63, -83,-133, -45, -48, 20, 83, 2,-123, -78,-158,-144; /M: SY='E'; M= -45,-140, -41, 59, -69,-149,-125, 42, 5, -35, 20, 36, -30, 38, -56, -42, 35, -41, -9,-144; /M: SY='E'; M= 54, 11, -52, 76,-154, -74,-126, -24, -62, -18,-128,-127, 0, 32, -9, -17,-119, -81,-160,-154; /M: SY='K'; M= -40,-153, -19, 58,-160,-140, -55, -31, 81,-151, -33, -45, -23, -21, 22, 27,-118,-140,-171,-153; /M: SY='Q'; M= -11, -32, -49, 56,-139,-144,-111,-136, 29, -34, -10, 21, -40, 83, -19, -14,-121, -17,-144, 16; /M: SY='R'; M= -43,-161, 15, -28,-156,-147, -35, -68, 24, -43, -33, 9, -64, -33, 103,-126,-129, -40, 1,-147; /M: SY='L'; M= -62,-134, -31,-149,-116, -35, -39, 58, 8, 65, 46, -24,-162,-135, -27, -46, -63, -63,-153,-139; /M: SY='Q'; M= -25,-155,-120, -1,-156,-144, 7,-148, 59, -49,-127, 15, -31, 82, 63, -56, -54, -53,-154,-146; /M: SY='A'; M= 62, -1, -34,-127,-138, -52,-131, 2, 8, -6, 33, -26, -34, -2, 42, -3, -61, -37,-149, -45; /M: SY='L'; M= -20, -13, -31,-146, 19,-162, 8, 14, 12, 68, -4, -65,-161, -41,-136, -45,-128, 7,-140, -13; /M: SY='W'; M= 39,-138,-130, -31,-139,-135,-127, -61, 68, -78, 41, -37, -27, 4, 25, 25,-116,-131, 79, -36; /M: SY='S'; M= 43,-131, -13, -9, -24, -29,-130, 10, 30, -8, -44, 4,-142, -11, 8, 43, -26, -66,-155,-140; /I: E1=0; IE=-255; DE=-255;» more |
Numerical results [info]
| Total number of hits | 50 in 50 different sequences |
| Number of true positive hits | 49 in 49 different sequences |
| Number of 'unknown' hits | 0 |
| Number of false positive hits | 1 |
| Number of false negative sequences | 0 |
| Number of 'partial' sequences | 0 |
| Precision (true positives / (true positives + false positives)) | 98.00 % |
| Recall (true positives / (true positives + false negatives)) | 100.00 % |
Comments [info]
| Matrix type [info] | protein_domain |
| Scaling database [info] | reversed |
| Author [info] | CJA_Sigrist |
| Taxonomic range [info] | Eukaryotes |
| Maximum number of repetitions [info] | 1 |
| Feature key [info] | DOMAIN |
| Feature description [info] | HSA |
| Version [info] | 5 |
Cross-references [info]
| UniProtKB/Swiss-Prot True positive sequences |
49 sequences
AEF1_GIBZE (Q4IB96), BRM_DROME (P25439), DOM_DROME (Q9NDJ2), EAF11_USTMA (Q4P209), EAF1A_ARATH (F4J7T3), EAF1B_ARATH (F4J7T2), EAF1_ASPFU (Q4WP03), EAF1_CANAL (Q5A119), EAF1_CRYNB (P0CO99), EAF1_CRYNJ (P0CO98), EAF1_DEBHA (Q6BI82), EAF1_EMENI (Q5B4Q8), EAF1_EREGS (Q756L0), EAF1_KLULA (Q6CMB8), EAF1_NEUCR (Q7SBU6), EAF1_YARLI (Q6C7K8), EAF1_YEAST (Q06337), EAF_SCHPO (O59773), EP400_HUMAN (Q96L91), EP400_MOUSE (Q8CHI8), HEPF1_PLAF7 (C0H4W3), PIE1_ARATH (Q7X9V2), SMCA2_HUMAN (P51531), SMCA2_MOUSE (Q6DIC0), SMCA4_BOVIN (A7Z019), SMCA4_HUMAN (P51532), SMCA4_MOUSE (Q3TKT4), SMCA4_RAT (Q8K1P7), SNF21_SCHPO (Q9UTN6), SNF22_SCHPO (O94421), SNF2_YEAST (P22082), SRCAP_HUMAN (Q6ZRS2), SSL1_CAEEL (Q9NEL2), STH1_YEAST (P32597), SWR1_ASPFU (Q4WAS9), SWR1_CANAL (Q59U81), SWR1_CANGA (Q6FK48), SWR1_DEBHA (Q6BKC2), SWR1_EMENI (Q5ARK3), SWR1_EREGS (Q759G7), SWR1_GIBZE (Q4IAK7), SWR1_KLULA (Q6CJ38), SWR1_NEUCR (Q7S133), SWR1_SCHPO (O13682), SWR1_USTMA (Q4P328), SWR1_YARLI (Q6CA87), SWR1_YEAST (Q05471), SWSN4_CAEEL (G5EF53), SYD_ARATH (F4IHS2)» more
|
| UniProtKB/Swiss-Prot False positive sequences |
1 sequence
YPF17_PLAF7 (Q8ILR9) |
| PDB [Detailed view] |
29 PDB
4I6M; 5I9E; 5Y81; 6GEJ; 6GEN; 6IGM; 6K15; 6KW3; 6KW4; 6KW5; 6LTH; 6LTJ; 6TDA; 6UXV; 6UXW; 6V8O; 6V92; 6VZ4; 6VZG; 7C4J; 7EGM; 7EGP; 7VDT; 7VDV; 7VVY; 7VVZ; 7Y8R; 7YFN; 8ESC » more |