PROSITE entry PS51195

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51195
Entry name [info]	Q_MOTIF
Accession [info]	PS51195
Entry type [info]	MATRIX
Date [info]	01-MAR-2006 CREATED; 10-MAY-2017 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51195
Associated ProRule [info]	PRU00552

Name and characterization of the entry

Description [info]

DEAD-box RNA helicase Q motif profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=29;
/DISJOINT: DEFINITION=PROTECT; N1=3; N2=27;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.3100777; R2=0.0079956; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2591.0996094; R2=0.9042146; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=900; H_SCORE=3405; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=650; H_SCORE=3179; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-17; D=-80; I=-80; B1=-400; E1=-400; MI=-255; MD=-255; IM=-255; DM=-255;

...

                A   C   D   E   F   G   H   I   K   L   M   N   P   Q   R   S   T   V   W   Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='M';  M= -1,-54,  0,  3, -1,-28,-12,-24, 18,  0, 28,  2,-15, -4,  6, 14, 19,-11, 19,-19;
/M: SY='S';  M=  8,-52, -7,  9, -9, -7,  4,-42, 15,-37, -2,  8,-22, -1,  4, 44, 27,-46, -1,-44;
/M: SY='F';  M=-53,-55,-27,-28,101,-60,-28,-16,-47,-23, -7,-20,-63,-59,-54,-12,-37,-29, 71,  2;
/M: SY='S';  M= 21,-20, 31, 31,-57,-24,  3,-54, 14,-25,-31,  5,-47, 22,-22, 38, -4,-43,-63,-38;
/M: SY='E';  M=-19,-30, 42, 52,-13,-16,  9,-56, -6,-32,-25, -2,-30, 42, -7, 17,-22,-39,-61,-34;
/M: SY='L';  M= -1, 16,-30,-44, 40,-28,-48,  0,-53, 46, 36,-40,-22,-50,-54,  6,-25, -8,-17,  6;
/M: SY='G';  M=-14,-27,  2,-18,-23, 56, -1,-47,-12,-53,-50, 36, 37,  2,-19,  5,-29,-38,-59,-32;
/M: SY='L';  M=-35,  0,-66,-60, 21,-66,-54, 37,-59, 64, 16,-61,-63,-54,-58,-35,-42, 16,-52,-33;
/M: SY='P';  M=-28, 10, 15,-15,-56, -6, 42,-41,  2,-37,-25, 17, 50,-13,-21, 50,-13,-47,-65,-27;
/M: SY='P';  M= -7,-61, 31, 38,-63,-12,-15,-59, 11,-60,-23, -2, 69, -2, -5,  8,-20,-56,-35,-54;
/M: SY='W';  M=  4,-58, 18, 34,-13,-48, 19,-30,  4,-36,-25,  3, -4,  8, 10, 10,  4,-33, 65,  6;
/M: SY='I';  M=-34,-36,-63,-58,-23,-57,-57, 54,-56, 48, 14,-57,-59,-40,-48,-43, 11, 37,-58,-39;
/M: SY='M';  M=-29,-13,-56,-50,-33,-49,-31, 21,-11, 48, 54,-14,-58,  3, -1,-12,-17, 12,-56,-14;
/M: SY='Q';  M=-12,-59,  5, 39,-42,-23,-22,-38, 38,-29,-46, 14,-48, 40, 36,  5,-21,-44,-60,-48;
/M: SY='A';  M= 49,-50,-20, -9,-56, 14,-10,-38,-24,-31,-24, 46,-50, -3,-13,  9,  5,-16,-63,-51;
/M: SY='L';  M=-36, 24,-67,-61,-28,-68,-57, 50,-59, 58, 20,-62,-62,-55,-59,-55,-42, 28,-57,-39;
/M: SY='K';  M= -3,-56, 10, 29,-43,-28, -9,-43, 36,-33,-27, 17,-36, 19, 28, 10,  6,-39,-58, -3;
/M: SY='E';  M= -6,-58, 39, 44,-58,-19, -2,-57, 30,-33,-49, 14,-47, 15, 22, -1,-11,-40,-62,-17;
/I:         I=-19; MD=-61;
/M: SY='M';  M= 16,-17,-49,-32,-29,-43,-14,-11,  7, 28, 47,  8,-55, 29,-10,  9,-26,-11,-56, -4; D=-19;
/I:         I=-19; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='G';  M=-24,-58,-18,-14,-64, 76, 10,-68,  8,-66,-55, 35,-51,-25,-27, -4,-44,-63,-61,-55; D=-19;
/I:         I=-19; DM=-61;
/M: SY='F';  M=-53,-58,-64,-62, 82,-64,-40, 26,-56, -6,-12,-58,-65,-56,-54,-54,-47,-17, 48, 80;
/M: SY='T';  M=-31,-54,-10, 33,-52,-42,-18, -9, 28,-27,-42,  1,-26, 22, -7, 15, 46,  2,-62,-24;
/M: SY='K';  M=-11,-27, -9, 32,-35,-46, 14,-38, 46,-35,-44, -7,-47, 23, 35, -5, 20,-14,-60,-36;
/M: SY='P';  M=-22,-15,-52,-41,-56,-39,-50,-44,-46, -4, 41,-54,108,-48,-56,-45,-14,-38,-60,-56;
/M: SY='T';  M=-27,-44,-41,-43, -2,-48,-48,-40,-40,-22,-26,-30,-43,-43,-33, 27, 96,-34,-65,-43;
/M: SY='P';  M=  4,-62, -5, 30,-62,-41,-14,-54,  5,-39,-49,-43, 90,-15, -9,  0,-16,-41,-61,-56;
/M: SY='I';  M=-42,-55,-66,-63,-22,-69,-67, 82,-59,-11,-20,-58,-25,-58,-62,-52,-20, 55,-59,-40;
/M: SY='Q';  M=-41,-67,-36,-16,-72,-49,-29,-57,-21,-53,-39,-32,-48,123,-22,-30,-44,-59,-54,-43;
/M: SY='A';  M= 38, 22,-32, 18,-57,-33,-27,-33, 26,-45,  1,-28,-48, 33, 10, 34, -9,-31,-60,-49;
/I:         E1=0; IE=-255; DE=-255;

» more

Post-processing [info]

PROMOTED_BY

PS51192

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	1'183 in 1'182 different sequences
Number of true positive hits	1'183 in 1'182 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	22
Number of 'partial' sequences	1

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	98.17 %

Comments [info]

Taxonomic range [info]	Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	2
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	N_Hulo
Version [info]	5

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	1182 sequences BOYB_DROME (Q9VNP5), CGH1_CAEEL (Q95YF3), CRHR_SYNY3 (Q55804), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	22 sequences DBP3_ASPCL (A1C5V3), DBP3_ASPNC (A2QFL3), DBP3_ASPTN (Q0CL13), » more
UniProtKB/Swiss-Prot 'Partial' sequences	1 sequence RH1_CATRO (P85441)
PDB [Detailed view]	217 PDB 1FUU; 1HV8; 1QDE; 1QVA; 1S2M; 1T6N; 1VEC; 1XTI; 1XTJ; 1XTK; 2DB3; 2G9N; » more