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PROSITE entry PS51193


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51193
Entry name [info] HELICASE_ATP_BIND_2
Accession [info] PS51193
Entry type [info] MATRIX
Date [info] 01-APR-2006 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51192
Associated ProRule [info] PRU00541

Name and characterization of the entry

Description [info] Superfamilies 1 and 2 helicase ATP-binding type-2 domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=280;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=275;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.5287702; R2=0.0044709; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=58353.0000000; R2=0.0000000; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1560; H_SCORE=58353; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1112; H_SCORE=58353; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-14; D=-40; I=-40; B1=-1000; E1=-1000; MI=-155; MD=-155; IM=-155; DM=-155;
...
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Post-processing [info]

PROMOTED_BY PS51194
COMPETES_HIT_WITH PS51192; PS51194(30); PS51196

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 96 in 96 different sequences
Number of true positive hits 96 in 96 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 5
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.05 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] Helicase ATP-binding
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
96 sequences

CHL1_ASPCL  (A1CJ34), CHL1_ASPFU  (Q4WWE9), CHL1_ASPNC  (A2QY22), 
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UniProtKB/Swiss-Prot
False negative sequences
5 sequences

TFNPH_ASFB7 (Q89581), TFNPH_ASFK5 (P0C9B3), TFNPH_ASFM2 (Q89926), 
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PDB
[Detailed view]
78 PDB

2VSF; 3CRV; 3CRW; 4A15; 5FMF; 5H8C; 5H8W; 5IVW; 5IY6; 5IY7; 5IY8; 5IY9;
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