PROSITE entry PS51192

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51192
Entry name [info]	HELICASE_ATP_BIND_1
Accession [info]	PS51192
Entry type [info]	MATRIX
Date [info]	01-APR-2006 CREATED; 13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51192
Associated ProRule [info]	PRU00541

Name and characterization of the entry

Description [info]

Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=170;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=165;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.1345696; R2=0.0062874; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=24072.0117188; R2=6.5221872; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1331; H_SCORE=32753; N_SCORE=9.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=854; H_SCORE=29642; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-18; D=-70; I=-70; B1=-200; E1=-200; MI=-205; MD=-205; IM=-205; DM=-205;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-205; BD=-205;
/M: SY='I';  M=   9, -45,   4, -17,  -2, -40, -11,  53, -10,  13,  11, -11, -12, -48, -16, -25, -21,   4,  15, -37;
/M: SY='P';  M=  -8, -28, -23,   1,  11,  -5, -14,  -7,   8,   7,  10, -22,  43, -16, -13,   2,  12, -28, -71,  11;
/M: SY='L';  M=  15, -22, -31, -12, -20,   9, -18, -11, -10,  22,  -4, -15,   0, -10,  12,   2,  -4,   8, -74,  -6;
/M: SY='W';  M=  10, -41, -46, -22,  -8, -37,   3,  33, -11,  25,  -3,   6, -40, -44, -31,  -1, -17,   9,  37,  23;
/M: SY='L';  M=   9,  -6,  -4,  21, -44, -31,  10, -21,   8,  26, -10,  10, -24,   2,   3,  15, -37, -16, -25, -22;
/M: SY='K';  M= -25,  -4,  -3,  16, -50,  -1, -13, -31,  30, -15,  -8,  24, -10,  26,  28,  25, -26, -39, -77, -21;
/M: SY='G';  M= -16, -75,  -6, -18, -16,  57,  21, -63,  24, -33,  -2,  37,   7, -11, -12, -17, -28, -72, -75, -19;
/M: SY='R';  M= -38,   6,  -8,  14, -54, -26,  31, -28,  41, -18,  21,   9,  -9,  27,  44, -11, -29, -38, -77, -19;
/M: SY='D';  M= -28, -73,  62,  -8, -54,  10,   2, -27, -30, -63, -68,  58, -20, -17,   1,  29, -15, -33, -85, -26;
/M: SY='C';  M= -16,  43, -24, -68,  23,  14, -46,   9, -34,   2,   5, -36, -74,   1,  -8, -30,  20,  40, -40, -29;
/M: SY='I';  M= -21, -71, -81, -77,   6, -83, -74,  68, -74,  45,  13, -75, -77, -48, -65, -54,  -1,  24, -71, -15;
/M: SY='L';  M=  18, -10, -79, -75, -40,   4, -74,  39, -74,  48,   7, -73, -76, -70, -75, -50, -34,  40, -76, -60;
/M: SY='C';  M=  39,  46, -31,  -6,   6, -30,   2,   0, -37, -16, -26, -25, -71,  28, -15,   3,  -8,  19,   9, -41;
/M: SY='M';  M=  47, -32,  43, -59, -50,  33,   7, -30, -49,   1,  47, -55, -47, -60, -68,  -1, -35, -40,  12, -64;
/M: SY='P';  M=  -1, -41,  22,  43, -64, -48,   8, -34,   9, -72, -43, -41,  74,  26, -12, -17, -44,  -8, -80, -70;
/M: SY='T';  M= -35,  -7, -62, -62, -65, -69, -66, -52, -60, -55,  68, -41,  10, -27, -66, -14,  97,  -5, -85, -63;
/M: SY='G';  M=  -6, -38, -32, -37, -41,  50, -18, -44, -26, -42, -37, -25, -34, -33, -38, -11, -25, -41, -37, -38;
/M: SY='S';  M=  13,  21, -63, -12, -29, -28, -63, -56, -38,  24,   6, -56, -44, -57, -65,  66,  28, -20, -77, -14;
/M: SY='G';  M= -25, -38, -32, -28, -41,  51, -35, -45, -27, -43, -38, -25, -34, -33, -38, -25, -25, -42, -37, -39;
/M: SY='K';  M= -31, -38, -27, -21, -39, -35, -14, -40,  55, -39, -33, -17, -31, -20, -12, -28, -29, -37, -36, -33;
/M: SY='T';  M= -21, -31, -29, -30, -24, -32, -33, -30, -29, -32, -17, -23, -30, -30, -33,  16,  54, -26, -43, -32;
/M: SY='L';  M=   7, -10, -70,   2,  24, -57, -27,  24, -40,  44,  -9, -53, -74, -42, -20, -39,  26,   6, -71, -21;
/M: SY='Q';  M=  32,  42, -67, -30,   0, -49, -66,  23, -36, -30, -34, -60, -70,  63, -37, -12,  30,  18, -26, -60;
/M: SY='Y';  M=  37, -24, -72, -70,  54,  -6, -62,  -1, -52, -13,   1, -43, -74, -45, -69,   1,  15,  -1, -58,  56;
/M: SY='I';  M=  15, -14, -51,  -9,  -6, -26, -68,  35, -66,  26,  16, -50,  22,  17, -52, -22, -11,  20, -74, -31;
/M: SY='L';  M=  12,   0, -70, -37,   2, -63, -28,  31, -16,  37,   4,  -9, -27,  15, -20,  -9,   3, -15, -70,  10;
/M: SY='P';  M=  26, -20, -73, -51,  32, -39, -42,  25, -51,   8, -17, -69,  68, -33, -52, -20, -21,  -4, -68,   5;
/M: SY='I';  M=  30,   7, -77, -55, -11, -36, -72,  51, -71,  31,  49, -70, -53, -67, -73, -15,  -6,  13, -75, -58;
/I:         I=-7; MD=-21;
/M: SY='L';  M=  16, -73, -55, -12,  -5, -40, -24,  17,   0,  41,  -3, -54, -48, -44, -31, -33, -30,   2,  30,  39; D=-7;
/I:         I=-7; MD=-21;
/M: SY='Y';  M= -17, -45,   6,  36, -22, -32,  26, -34,  -3, -13, -12,   8, -52,  32,   3,  -5,  -7, -32,   3,  39; D=-7;
/I:         I=-7; MD=-21;
/M: SY='H';  M=   8, -74, -15, -15, -13, -57,  31, -17,   6,  27,   0,  -7, -74,   7,  -6,  -8,   6, -10, -72,  26; D=-7;
/I:         I=-7; MD=-21;
/M: SY='L';  M= -13, -30, -88, -83,  -2, -17,  -4,  16, -27,  39, -12, -40, -89, -59, -48, -33, -72, -11, -11, -18; D=-7;
/I:         I=-7; MD=-21;
/M: SY='H';  M= -56,   1, -20, -21, -38, -78,   8, -13,   4,  -8, -22, -11, -94, -13,  -9, -36, -55, -50,  -9,   5; D=-7;
/I:         I=-7; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='Q';  M=  11, -13, -24,   6, -88, -39, -24, -73,   8, -50, -39,  -9, -38,  14,  12,   0, -29, -39,  -9, -40; D=-7;
/I:         I=-7; DM=-21;
/M: SY='N';  M= -18, -80, -13,   9, -21,  -9, -11, -24,  14,   9, -45,  15,   5,  -3, -15,   3, -11, -29, -82, -31; D=-7;
/I:         I=-7; DM=-21;
/M: SY='R';  M=   5, -29,  12,  -7, -48,   0, -21, -19,  25, -45, -66,  23,  -9,  18,  25,   2,  -9, -53, -79,  -4; D=-7;
/I:         I=-7; DM=-21;
/M: SY='G';  M=  -6, -75,  -6,   4, -25,  48,  24, -41,  19, -59, -45,  25,   2,  14,   0,  -9, -12, -34, -32, -15;
/M: SY='K';  M= -39, -13, -22, -31, -21,  36, -23, -16,  43, -14, -27, -22,  33,   9,   1,  -5, -14, -25,  14, -10;
/M: SY='Q';  M= -62, -79, -47, -37, -17,   2, -14, -26,  46, -18,  -8, -23,  32,  48,  48, -20, -17, -41,   9, -27;
/M: SY='V';  M=  30,  26, -71, -68,   0, -24, -30,  25, -46, -32, -52, -26,   0, -67, -71,   4,  33,  49, -78, -41;
/M: SY='L';  M= -12, -41, -79, -74, -24, -42,  27,  37, -74,  60, -24, -51, -78, -69, -74, -57, -29,  35, -22, -14;
/M: SY='I';  M= -62,   3, -82, -56,  25, -66, -45,  61, -75,  12,  -6, -76, -56, -74, -76, -70, -58,  56, -65,  43;
/M: SY='I';  M= -52,   0, -81, -76, -15, -68, -74,  53, -74,  45,  42, -74, -36, -71, -75, -46,  11,  43, -76, -56;
/M: SY='V';  M=  36,  39, -53, -20, -11, -66, -38, -20, -64, -23, -14, -62, -51,  -1, -68,  23,  28,  52, -80, -42;
/M: SY='P';  M= -56, -22, -29, -47, -80, -69,  25, -44, -51, -63, -33, -22, 116, -64, -72, -40, -30,  -8, -82, -75;
/M: SY='T';  M= -50, -69, -58,  -4, -64, -69, -61, -40,  -8,  21,  -7,  32,   7, -38,  22,   4,  71, -33, -29, -64;
/M: SY='R';  M= -32, -75, -11, -10, -69, -61, -28,   7,  35, -29, -58, -19, -44, -38,  67,  22,   7,   8, -78, -46;
/M: SY='E';  M=  25, -31, -36,  48, -65, -51, -22, -11, -57,  -7, -22, -11,   9, -53, -63,  35,  23,   1, -77,   5;
/M: SY='L';  M=  -5, -68, -80, -73, -45, -80, -69, -11, -74,  80, -21, -50, -53, -33, -73, -46, -24,  10, -73, -39;
/M: SY='A';  M=  58,  11, -35, -65, -64, -22, -40,   1, -41, -18,  39, -35, -38, -32, -33, -11,  -1,  37, -24, -42;
/M: SY='E';  M=  -1, -74,   6,  38, -27, -44,  19,  -9,  -4, -22,   2,  36, -26,  28,  18,  -2, -18, -16, -25, -10;
/M: SY='Q';  M= -34, -35,  16,  14, -77, -66, -33, -50, -34, -60, -37,  15, -49, 104,  -9, -16, -24, -60,  75, -59;
/M: SY='W';  M= -28, -75, -14, -43, -34, -75,  11,  36,  -2,   1,  26, -47, -32,  49, -51, -47,  19,  24,  85, -53;
/M: SY='Y';  M=  22, -22, -46,   3,   0, -35,  14,  -9,   1,  -5,  -8, -20, -36,   2, -21,   2, -23,  10, -20,  61;
/M: SY='E';  M= -12, -75,  15,  55, -76, -33, -21, -43,  23, -42, -15,  38, -36,  27,  14,  10,   4, -69, -80, -46;
/M: SY='E';  M=  -6, -75,   0,  48, -12, -59,  -2, -12,   3, -25, -25,  11, -47,  22,  28, -19,   1,   8,  13, -19;
/M: SY='F';  M=  -1,   3, -58, -21,  58, -46, -69,  16, -47,  39,  26, -42, -78, -28, -71, -56, -38,  22,  30, -21;
/M: SY='K';  M=   3, -74, -34,  19, -16, -20, -17, -25,  40,  -9, -10,  -9, -50,  30,  36,  10,  -8, -38, -73,  -7;
/M: SY='K';  M=  -1, -75,  11,  22, -29, -27,  22, -40,  37, -41, -15,   6,  -4,  17,  15,   6,   5, -28,  32, -15;
/M: SY='W';  M= -11, -25, -41,  -1,  36, -74,   7,  10, -21,  28,  -2, -27, -23, -14,   8, -18, -13,  -9,  75,   4;
/M: SY='F';  M=   1,   3, -51, -19,  48,  17, -13, -26,  -2,  16,  12,  -7,   6, -62, -24,  -1,  -1, -28, -18,  -4;
/M: SY='P';  M= -23, -43,  21,  28, -29,  13, -60,  -7,  20, -13, -21,  13,  40,  20, -13,  -9, -40, -30, -76, -22;
/M: SY='F';  M=  -7, -10, -10,  10,  33,   1,  29, -21,  15,   3,  -7,  -5,  10, -21,  -3,  -4, -38, -35, -68,  17;
/I:         I=-5; MD=-16;
/M: SY='C';  M=   3,  19, -36,  -2,   0, -15, -15,   1,  15,  15,   6,  17,  -9, -15, -19, -23,  -6,   0,   1,  -7; D=-5;
/I:         I=-5; MD=-16;
/M: SY='G';  M=   5, -14,   1, -11, -42,  21,  18, -24,  -6, -17, -13,   7,  18, -10, -10,  15, -34,   7, -11, -11; D=-5;
/I:         I=-5; MD=-16;
/M: SY='V';  M= -22, -10, -10, -26, -19,  10, -68,  22,   1,  12,  18, -11, -38, -30, -19, -14,  -6,  24, -37,  -5; D=-5;
/I:         I=-5; MD=-16;
/M: SY='K';  M= -24, -44, -13,  13, -21, -37,  16,  15,  22,  -2, -11,  -5, -14, -10,  -8,   2,   0,   0, -82, -47; D=-5;
/I:         I=-5; MD=-16;
/M: SY='Y';  M= -21,  10, -33, -25,   3, -32, -23,  18,   9, -11, -14, -19, -54, -39, -37,  -4,  -2,  25,   2,  42; D=-5;
/I:         I=-5; MD=-16;
/M: SY='H';  M=  -2,  20, -72, -25,  12,   8,  28,  -3, -15, -13,  -9, -16, -47, -28, -20,   6, -30,   5, -75,  21; D=-5;
/I:         I=-5; MD=-16;
/M: SY='V';  M= -34,  -2, -44, -26, -50,  11,  11,  -2, -29, -15, -29, -27, -26, -39,  -2,  12,  -8,  13, -29,   7; D=-5;
/I:         I=-5; MD=-16;
/M: SY='L';  M= -32, -35, -32, -17, -19, -17, -78,   9, -53,  11, -27,  -6, -31, -32, -31,   8, -25,   7, -38, -17; D=-5;
/I:         I=-5; MD=-16;
/M: SY='Y';  M= -57, -13, -68, -64, -29, -44, -53, -19, -29,   3, -17, -41, -28, -56, -83,  13,  16, -16, -84,  35; D=-5;
/I:         I=-5; MI=0; MD=-16; IM=0; DM=-16;
/M: SY='G';  M= -15,-100, -41,   4, -66,  37, -52, -32, -28, -74, -90, -41, -66, -32,  -2, -31, -85, -92, -98, -39; D=-5;
/I:         I=-5; DM=-16;
/M: SY='G';  M=  -6, -92,  -4,  -6, -52,  33, -44, -59, -14, -56, -58, -15,  -7, -24,  -2, -16, -47, -62, -95, -86; D=-5;
/I:         I=-5; DM=-16;
/M: SY='T';  M= -22, -49,   6,  19, -59,   5,  -9, -54, -16, -40, -24, -25, -27,  18,  -2,   4,  23, -12, -36, -28; D=-5;
/I:         I=-5; DM=-16;
/M: SY='Y';  M= -10, -82, -11, -13, -11,   0, -43, -18,  20, -58, -25, -12, -20,  -4,  18,   6,  -1, -29,  11,  21; D=-5;
/I:         I=-5; DM=-16;
/M: SY='K';  M= -18, -80,  20,  19, -39, -37, -28, -14,  25,  -2, -20, -16, -21,  -4,   6,   7, -19, -32, -81,  -6; D=-5;
/I:         I=-5; DM=-16;
/M: SY='R';  M= -26, -80,  -7,  23, -18, -31, -23, -13,  21, -29, -10, -38, -30,  18,  29,   8,   0, -28,   7,   9; D=-5;
/I:         I=-5; DM=-16;
/M: SY='D';  M=  -1, -78,  20,  16,  -1, -37, -45,   5,   7, -31,  -9, -29, -11,   9,  17,  -6,  -5, -11, -75,  14; D=-5;
/I:         I=-5; DM=-16;
/M: SY='Q';  M= -36, -40,   1,  20,  21, -54,  -7, -24, -10,   3, -14,   1, -35,  53,  21,  -2, -18, -28,  37, -57; D=-5;
/I:         I=-5; DM=-16;
/M: SY='E';  M= -37, -47,  32,  33, -15, -26, -39,  -3,  16,  -2,  -2,   6, -18,   1,   6,  -2, -32, -21,  12, -13; D=-5;
/I:         I=-5; DM=-16;
/M: SY='K';  M=  -9, -76,  13,  21, -32,  -7, -11, -34,  32, -12,  -4,   5,  -2,  21,  23,  -5, -16, -19,  -1, -64; D=-5;
/I:         I=-5; DM=-16;
/M: SY='K';  M= -11,  -5,   1,  10, -18, -37,   1,  -1,  29,   7,   1,   0, -69,  17,  16,   6,   8, -13, -75, -14;
/M: SY='L';  M=  -8,  -5, -25,   4,  -9, -21, -39,   5,  18,  23, -52,   3, -38,  12,   4,   2, -14,  -6,  19,  16;
/M: SY='S';  M=   0,   2,  -1,  -8,  -6, -41, -11,  -4,  18,  -3,  20,  19,  -3,   1,  15,  26, -25, -27,   8, -15;
/M: SY='K';  M= -17, -44,  13,   5, -54,  24,   9, -19,  27, -28, -12,  14,  24,   4,  -4,   9,  -2, -55, -75,   9;
/M: SY='K';  M=  -7,  -2,  18,   7, -46,  14,  -5, -60,  37, -46, -66,  32, -13,  23,  26,  18, -12, -71, -80, -66;
/M: SY='Y';  M=  11,  34, -66, -26,  31, -19,  19,  -1, -21, -32, -56,  -6,  32, -22, -20,  -5,  20,  -7,  -6,  40;
/M: SY='D';  M= -57, -43,  69, -11, -78,  -8,  62, -62,  16, -49, -28,  43,  -8,  28,   1, -27, -22, -62, -88, -63;
/M: SY='I';  M= -30, -41, -83, -79, -12, -67, -80,  77, -61,  12,  10, -54, -76, -74, -77, -55, -41,  57, -76, -57;
/M: SY='V';  M= -40,  12, -30, -48,  -2, -81, -25,  42, -19,  36,   8, -71, -76, -69, -53, -53,   5,  52, -75, -11;
/M: SY='I';  M= -36, -72, -81, -78,  19, -83, -43,  64, -74,   3, -26, -75, -78, -73, -75, -29, -43,  60, -66,  44;
/M: SY='T';  M=  29, -24, -46, -37, -35,  38, -67,   0, -64, -17,  50, -43, -67, -62, -54,  12,  52, -12, -78, -64;
/M: SY='T';  M= -30, -16, -58, -60, -69, -40, -66, -41, -19, -56, -43, -18, -30, -59, -43,  34,  99, -32, -86, -66;
/M: SY='P';  M= -23, -40,  -8, -36, -15, -69,  28, -23, -41, -66, -41,   3,  82, -31,  -7, -12,  -5, -18, -18,  66;
/M: SY='E';  M=   2, -75,   0,  51, -58,  50, -58, -51, -26, -68, -46,   9, -65,  44, -19,  21, -57, -59, -77, -45;
/M: SY='R';  M=  -9, -14, -66, -11,  10, -62, -19,  11,  13,  -5,  35, -61, -72, -14,  52,  -3,  15,   4, -70,  10;
/M: SY='L';  M= -14, -25, -83, -77,  28, -82, -73,  39, -76,  61,  -7, -77, -79, -72, -75, -57, -19,  25,  17, -23;
/M: SY='L';  M=  -8, -22,   8, -11,  14, -13, -13,  10, -31,  29,  -5,   0, -37, -12,  13,  -6,   7,  -1, -74, -21;
/M: SY='D';  M= -13, -42,  49,  -7,  -6, -24,  11, -40,  18, -10, -42,  34, -69,   2,  15,  22,  -3, -48, -78,  -7;
/M: SY='H';  M= -29, -38,  39,  13, -10, -40,  53, -38, -19,  19,  26,   9,  10, -11, -10,   3, -23, -30, -31, -16;
/I:         I=-6; MD=-18;
/M: SY='L';  M= -17, -25, -75, -41,  -5, -48, -11,  36,  -1,  37,   6, -44, -11, -43, -12, -26, -10,  -2, -28,  34; D=-6;
/I:         I=-6; MD=-18;
/M: SY='Q';  M= -31, -77,  27,  20, -18, -33, -15, -38,  17,   0, -17,   8, -41,  42,  23, -15,   5, -22, -78, -22; D=-6;
/I:         I=-6; MD=-18;
/M: SY='R';  M= -14,  -6,  -3,   7, -12, -36,  20, -50,   5, -12, -30,  23, -21,  14,  43,  -2, -10, -42,  -7, -64; D=-6;
/I:         I=-6; MD=-18;
/M: SY='D';  M= -49, -29,  26,  -4,  -8,   9,  -2, -13,   8,   8, -13,   6, -12, -18,  -3, -10, -23, -56,  19, -23; D=-6;
/I:         I=-6; MD=-18;
/M: SY='S';  M= -16, -80, -30, -39, -28, -26,  11, -36,  14, -17, -13,  20,   7,  -8,  11,  22,  -3, -29, -29,   3; D=-6;
/I:         I=-6; MD=-18;
/M: SY='L';  M= -33, -31, -28, -32, -17, -44, -21,   1,  -8,  20,   9,  14, -14, -23, -18,  -5, -12,  -3, -85, -23; D=-6;
/I:         I=-6; MD=-18;
/M: SY='W';  M= -13, -89, -10, -44,   6, -44, -36,   3,   0, -16, -45,  10, -16, -20,  -8,  -2, -40, -38,  16, -52; D=-6;
/I:         I=-6; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='L';  M= -33, -53, -37, -59,  23, -69, -47, -18, -41,  38,  27, -22, -36, -18,   0, -23, -28,   1, -81, -62; D=-6;
/I:         I=-6; DM=-18;
/M: SY='R';  M= -40, -81,   6,   6, -61, -12,  -8, -28,  27, -65, -19, -19,  -4,   5,  31,  25,  -9, -16, -32,   0; D=-6;
/I:         I=-6; DM=-18;
/M: SY='N';  M= -28, -25,  21,  11, -46, -20,  40, -65,  38, -48, -48,  46,   1,  10,  25,  -9, -26, -43, -83, -38; D=-6;
/I:         I=-6; DM=-18;
/M: SY='W';  M= -53,   5, -29, -76,  46, -81, -44,  23, -73,  30, -31, -32, -22, -73, -44, -72, -47,  31,  85,  35; D=-6;
/I:         I=-6; DM=-18;
/M: SY='D';  M= -13, -46,  42,   9, -53,  11,  15, -50,  23, -55, -67,  29, -68,  10,  22,  23,  -7, -45, -82, -36; D=-6;
/I:         I=-6; DM=-18;
/M: SY='Y';  M= -52,  30, -78, -74,  45, -65,   5,  -1, -69,  40,   5, -72, -80, -69,  -9, -58,   4,  16,   5,  59;
/M: SY='I';  M= -17,  12, -83, -78,  22, -82, -75,  53, -64,  43,  26, -77, -79, -73, -76, -52, -58,  47, -73, -53;
/M: SY='I';  M= -13, -41, -83, -57,  -1, -70, -82,  77, -75, -22,  -3, -76, -76, -74, -55, -68, -55,  65, -76, -57;
/M: SY='I';  M= -39,  -1, -83, -78,  24, -83, -74,  54, -55,  38,  34, -53, -78, -73, -75, -70, -32,  50, -72, -23;
/M: SY='D';  M= -52, -80, 117, -32, -87, -64, -53, -85, -55, -84, -83, -35, -67, -54, -63, -17, -56, -82,-102, -70;
/M: SY='E';  M= -59, -80,   7, 108, -83, -74, -54, -84, -42, -77, -73, -55, -56, -35, -52, -23, -44, -76, -81, -73;
/M: SY='A';  M=  62,  52, -69,  -4, -22,   5, -71,   3, -66, -30, -28, -65, -71, -18, -70, -25, -55,  35, -77, -43;
/M: SY='H';  M= -68, -81,  70, -45, -74, -68, 130, -86, -56, -73, -61, -40, -69, -11, -55, -24, -63, -84,-102, -46;
/M: SY='R';  M=  -8,  46,  -7,  14, -16, -47,  33, -46,   7, -17,  10,  -1, -71, -29,  56,   9, -11, -16, -78, -19;
/M: SY='M';  M=  -9, -15, -61, -58,  16, -43, -38,  46, -68,  38,  59, -45, -76, -66,  -6, -23,  -9,  11, -71, -15;
/I:         I=-5; MD=-15;
/M: SY='L';  M= -31, -73,  -1, -61,  -7,   2,  -6,  -4,  29,  34, -34, -15, -39, -25, -10,  25,  -7, -33, -73,   2; D=-5;
/I:         I=-5; MD=-15;
/M: SY='N';  M= -28, -43,  39,  12, -36,  14, -58, -31,   2, -23, -65,  48, -15,  20, -37,   2, -20, -21, -26,   6; D=-5;
/I:         I=-5; MD=-15;
/M: SY='W';  M=  -2, -76,  10,  13, -26, -36, -41, -24,  11, -11,  45,  11, -13,  16,   6,  16, -24, -38,  54, -22; D=-5;
/I:         I=-5; MD=-15;
/M: SY='G';  M= -21, -76,  -5,   6, -42,  43,  -9, -63,   0, -65,   0,   9, -69,  36, -23,  28,  22, -72, -80, -36; D=-5;
/I:         I=-5; MD=-15;
/M: SY='F';  M=  -3, -29,  24, -20,  44, -14,  36, -10, -19, -37, -63, -13, -36, -50,  20,  20, -21, -41, -33, -14; D=-5;
/I:         I=-5; MD=-15;
/M: SY='Q';  M=   1, -79,   8,  18, -16,  -1, -12,  -2,  -2, -32, -25, -11,   3,  19,  -8,   4,  -3, -39, -23,  13; D=-5;
/I:         I=-5; MD=-15;
/M: SY='F';  M=  -4, -46,  10,   9,  15, -19,   4, -25,  -9,   0, -60,  -2,   8,  12,   3, -30,  -1,   0, -80, -47; D=-5;
/I:         I=-5; MD=-15;
/M: SY='W';  M= -54, -50,  24,  -1,  -6, -78, -11, -15, -51,   4, -23, -19,  -9,  12,  20, -20,  15,  -2,  39,  15; D=-5;
/I:         I=-5; MD=-15;
/M: SY='I';  M= -24, -29, -33,   8, -56,  -9, -51,  18, -11,   6,  -5, -39,   9,   9,  -6, -24, -19,   0,  18, -39; D=-5;
/I:         I=-5; MD=-15;
/M: SY='E';  M=  -1, -15,  15,  23, -15, -53, -15, -17, -25, -32,   2, -17, -60, -35, -13, -10,  -5,  -4, -27,  16; D=-5;
/I:         I=-5; MD=-15;
/M: SY='Y';  M= -35, -21, -29,  -7, -17, -72,   9,  10, -10,   5, -25,  -9, -85,  -2,  -9, -27, -21, -12, -36,  23; D=-5;
/I:         I=-5; MD=-15;
/M: SY='I';  M= -15, -15, -68, -53, -41, -92, -16,  31, -27,   4,  -5, -82, -91, -15,   3, -20, -26,  -8, -44, -54; D=-5;
/I:         I=-5; MI=0; MD=-15; IM=0; DM=-15;
/M: SY='L';  M= -25, -24, -66, -41, -10, -51,   0,  13, -17,  26,  -4, -30, -90, -31, -30,  -7, -55, -20, -87, -16; D=-5;
/I:         I=-5; DM=-15;
/M: SY='R';  M= -30, -54, -23, -20, -78, -42, -17, -21,  32,  -4,   3, -26, -47,  -9,  32,   6, -13, -38, -25, -73; D=-5;
/I:         I=-5; DM=-15;
/M: SY='K';  M=  -6,   4, -37, -16,  -3, -26, -19, -61,  23, -17, -28,   7,  -5,  14,  16,  11, -10, -35, -79,  -2; D=-5;
/I:         I=-5; DM=-15;
/M: SY='L';  M=  -6, -28,   2, -15,  -3, -32,   6,   4,   4,  13,  -2,  -4, -39, -17,   4,   2,  -8, -30, -33,  -1; D=-5;
/I:         I=-5; DM=-15;
/M: SY='P';  M= -26, -32, -15,  -8,   0, -11, -24, -17,  23,   1,  -4,  16,  39, -22,  21,  -4, -40, -47, -76,  -4; D=-5;
/I:         I=-5; DM=-15;
/M: SY='P';  M=   2, -22,   6,  10, -12,  -6,  -4, -50,  18, -75, -68,  29,  41,   7,   8,   4,  -4, -40,  -8, -47; D=-5;
/I:         I=-5; DM=-15;
/M: SY='N';  M=  -8, -10,  32,   4, -58, -28,  17, -20,  11, -25, -43,  40,   1,   6,  -1,  24,  -2, -49, -84, -40; D=-5;
/I:         I=-5; DM=-15;
/M: SY='P';  M=   3,  10, -51, -28, -11, -31,   5,   7,  -8,  15, -18,  -9,  33, -12,  29, -29,  -9,   0, -35, -24; D=-5;
/I:         I=-5; DM=-15;
/M: SY='Q';  M= -37, -12, -24, -50, -42, -71,  32, -34,  19, -43, -37, -26,  30,  68,  55, -12,  -4, -36, -77, -16; D=-5;
/I:         I=-5; DM=-15;
/M: SY='I';  M= -48,  10, -71, -67,  12, -50, -42,  32,   3,  24,  31, -16, -53, -17,  20, -27,  29,  20, -73, -23;
/M: SY='I';  M= -38,-142,-163,-112, -10, -96,-147, 108,-150, 108,  34,-153, -86,-142,-151, -68,-117,  68,  -3, -58;
/M: SY='L';  M=  32,  31,-148, -86,   9,  48, -74,  13, -85,  93,  46, -86,-151, -92,-142, -67, -65,  15,-141,  -3;
/M: SY='M';  M= -80,  20,-160,-149, 111, -34,-133, -29,-107, 114, 115,-145,-101,-140,-113, -37, -15, -37, -71, -69;
/M: SY='S';  M= -63,-128,-114, -84,-141, -32,-124, -70,-115,-119, -32, -93,-125, -45,-126, 168, 138,-118,-165, -91;
/M: SY='A';  M= 167,-130, -71, -70,-153,  56, -83,-136, -86,-115,-127,-117, -15,-118,-135, -14, -40, -93,-153,-143;
/M: SY='T';  M= -65, -64,-116, -95,-103, -58,-133, -98, -86,-101,-121, -71,  -8, -87,-130,  42, 206, -84,-171,-132;
/M: SY='P';  M=   3, -51, -37, -51,  -1, -56, -41,  17, -66,  22,  32, -71,  85,  -7, -56, -52, -47,  -6,  -7, -26;
/M: SY='P';  M=  -9, -74,   1,  -9, -14,  -7,  -6,  18,  -9,  -3, -57,  11,  46,  -1,  -4,  24,   8, -21, -78, -63;
/M: SY='N';  M= -18, -74,  26,   9, -70, -16, -27, -40,  12, -19, -28,  53,  11,  40,  -3,   3, -10,  -9, -79,  -3;
/M: SY='N';  M=   3, -73,  19,  27, -19,   0,  -7, -59,   7, -33, -40,  54,  -8,  -2,   9,   4,   3, -39, -11, -22;
/M: SY='V';  M= -13, -72,  14,   5, -51, -32, -10,  20,  17,  -9, -19,  20, -50, -27,   8,   0,  19,  25, -79, -17;
/M: SY='E';  M= -15, -22,  20,  28,   9, -49, -61,  -3,  21,  17, -25, -26, -19,  11,  25, -45, -25,  -6,   9,  -8;
/M: SY='E';  M=  -9, -30,   8,  32, -31, -21,   2, -20,  23,   6, -22,  11, -14,  23,  12,  -1, -15, -24, -76, -11;
/M: SY='W';  M=  19, -34,  12,  34,   0, -34, -39,   2, -11,  20, -18, -11, -18, -12, -42,  -7, -17,  -9,  38, -12;
/M: SY='M';  M=  23,  10, -25,  -3,   8, -18,  11,  15, -17,  20,  32, -31, -26, -17, -22, -20, -12, -14, -19,  16;
/M: SY='W';  M= -18, -75, -26, -11,  38, -29, -12,  -8,  24,  -9,   1,  -2, -49,  20,   3,  -2, -14, -11,  88, -10;
/M: SY='S';  M= -10, -37,   2,   4,   4, -33,  -5, -22,   8,  26, -32,  12, -22,   6,  -6,  31,   0, -22, -33, -27;
/M: SY='N';  M= -19, -13, -41, -41,  26,  10,   9,   6, -14,  15,  20,  36, -34,   1, -19, -13, -19,   2, -35,  14;
/M: SY='L';  M=  10, -11, -12,  -8,  11, -26, -40,  12, -11,  35,  29, -19, -50,  -1, -20, -50,   8,  13, -74, -57;
/M: SY='N';  M= -30, -44, -14,   4,  -1, -12,  25, -13,  16, -10,   6,  43,  16,   4,  23, -20, -35, -20, -71,  26;
/M: SY='F';  M= -36, -74,  29,   1,  32, -72,  19,  16,   4,  25, -21,  23, -30, -10,  -3,  -9, -25, -17, -73, -24;
/M: SY='P';  M= -26, -44, -18, -16,   8,  -8, -24,   5, -10,  14,  21, -28,  51,   2,  -9, -51, -10,  19, -28,   3;
/M: SY='K';  M= -36, -25,  12,   6, -22, -33, -39,   6,  36,  -2,  12,   9,  13,  -6, -16,   5,  -1,   6, -75,   3;
/M: SY='P';  M= -29, -29, -31,  10, -18, -33,   1,   4,  -1,  -5, -21,  -6,  52,  -8,   6,  15,  10,   3, -75,   1;
/M: SY='I';  M= -26, -42,  -8,  14,   8, -14,   5,  30,   6,  12,   3,   2, -19, -23, -22,  -6, -33,  16,   6,  -8;
/I:         E1=0; IE=-205; DE=-205;

» more

Post-processing [info]

PROMOTED_BY	PS51194
COMPETES_HIT_WITH	PS51193; PS51194(30); PS51196

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	2'831 in 2'787 different sequences
Number of true positive hits	2'831 in 2'787 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	16
Number of 'partial' sequences	2

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	99.44 %

Comments [info]

Taxonomic range [info]	Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	2
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	N_Hulo
Feature key [info]	DOMAIN
Feature description [info]	Helicase ATP-binding
Version [info]	5

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	2787 sequences 009L_FRG3G (Q6GZW6), 055L_FRG3G (Q6GZS1), 172L_IIV6 (O55764), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	16 sequences CAS3_THET8 (Q53VY2), DHX32_MOUSE (Q8BZS9), DHX32_XENLA (Q5XH12), » more
UniProtKB/Swiss-Prot 'Partial' sequences	2 sequences NTP1_SWPVK (Q08513), RH1_CATRO (P85441)
PDB [Detailed view]	902 PDB 1A1V; 1C4O; 1CU1; 1D2M; 1D9X; 1D9Z; 1FUU; 1GKU; 1GL9; 1GM5; 1HEI; 1HV8; » more