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PROSITE entry PS51192


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51192
Entry name [info] HELICASE_ATP_BIND_1
Accession [info] PS51192
Entry type [info] MATRIX
Date [info] 01-APR-2006 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51192
Associated ProRule [info] PRU00541

Name and characterization of the entry

Description [info] Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=170;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=165;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.1345696; R2=0.0062874; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=24072.0117188; R2=6.5221872; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1331; H_SCORE=32753; N_SCORE=9.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=854; H_SCORE=29642; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-18; D=-70; I=-70; B1=-200; E1=-200; MI=-205; MD=-205; IM=-205; DM=-205;
...
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Post-processing [info]

PROMOTED_BY PS51194
COMPETES_HIT_WITH PS51193; PS51194(30); PS51196

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 2'831 in 2'787 different sequences
Number of true positive hits 2'831 in 2'787 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 16
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.44 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] Helicase ATP-binding
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
2787 sequences

009L_FRG3G  (Q6GZW6), 055L_FRG3G  (Q6GZS1), 172L_IIV6   (O55764), 
» more

UniProtKB/Swiss-Prot
False negative sequences
16 sequences

CAS3_THET8  (Q53VY2), DHX32_MOUSE (Q8BZS9), DHX32_XENLA (Q5XH12), 
» more

UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

NTP1_SWPVK  (Q08513), RH1_CATRO   (P85441)

		
PDB
[Detailed view]
902 PDB

1A1V; 1C4O; 1CU1; 1D2M; 1D9X; 1D9Z; 1FUU; 1GKU; 1GL9; 1GM5; 1HEI; 1HV8;
» more