PROSITE entry PS51186

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PURL: https://purl.expasy.org/prosite/signature/PS51186

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General information about the entry

Entry name [info]	GNAT
Accession [info]	PS51186
Entry type [info]	MATRIX
Date [info]	01-MAR-2006 CREATED; 07-APR-2021 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51186
Associated ProRule [info]	PRU00532

Name and characterization of the entry

Description [info]

Gcn5-related N-acetyltransferase (GNAT) domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=140;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=135;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.7210873; R2=0.0068247; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=23249.4824219; R2=4.3146853; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1258; H_SCORE=28677; N_SCORE=9.3; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=847; H_SCORE=26904; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-17; D=-50; I=-50; B1=-300; E1=-300; MI=-105; MD=-105; IM=-105; DM=-105;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-105; BD=-105;
/M: SY='M';  M=  -8, -31, -28,  -9, -21, -35, -84,  43, -28,  15,  56, -41,   1, -31, -27, -11,  -5,  27, -91,  -3;
/M: SY='E';  M= -12, -53,  18,  29, -40, -43,   9,   4,   7,  -8,  17,  19, -13, -17,  14, -23,  26,   5, -98, -56;
/M: SY='I';  M= -46, -32, -97, -63,  32, -61, -36,  65, -74,  30,   8, -68, -95, -64, -92, -70, -14,  36, -36,  27;
/M: SY='R';  M= -26, -40, -15,   3, -42, -58,  -3, -50,  14, -16, -16, -26,  -5, -15,  80,   1, -18, -12,   1, -13;
/M: SY='P';  M=  -4,  -3,  26,  34, -70, -48, -20, -22,  -4, -11, -50,   2,  40,  12,  -1,   7,  16, -21, -96, -15;
/M: SY='M';  M=  18, -10, -35, -18,  14, -40, -52,  18, -34,  36,  42, -28, -31, -59, -37, -31, -49,  24, -12,  16;
/M: SY='T';  M=   0, -89,  11,  17, -10, -41, -32,  -9,   9, -37, -40,  15,   4,   5,  14,  13,  49, -36, -38, -31;
/I:         I=-15; MD=-32;
/M: SY='P';  M=  -3, -55, -10,  44, -43, -42,  12, -23, -10, -16,  -3, -39,  50,   6,   6, -13,   5,  -6,   0, -31; D=-15;
/I:         I=-15; MI=-32; IM=-32; DM=-32;
/M: SY='E';  M=   8,  -5,  22,  43, -23, -12,   6, -21,  10, -37,  -4,  -5, -33,   6, -16,  15,  15, -25, -18, -45;
/M: SY='D';  M=  -8, -40,  85,  13, -61, -47, -15, -29, -21, -25, -29,  -2, -50,  -2,  -5,   8, -22, -23, -36, -28;
/M: SY='L';  M=   4, -53, -70, -41,  21, -61, -22,  27, -17,  44,  20, -38, -41, -38,   0, -34,  -4,   4,  39, -13;
/M: SY='E';  M=   6, -58,  33,  34, -37, -50,  19, -20,  13, -21,   6,  -3,  34,  13, -30,  -9, -31,  -7, -35,   2;
/M: SY='Q';  M=  18, -57,  30,  26,  -6, -14,  16, -28, -10,  -9,  -2, -29,   0,  31,  19,  -5, -17, -33, -94, -27;
/M: SY='I';  M= -11,   7, -95, -51,  25, -49, -13,  44, -71,  39,  23, -41, -51, -61, -48, -34, -23,  24,  40,   3;
/M: SY='Y';  M= -16,   3, -34,  -8,  20, -65,  -9,  13,   1,  19,  11, -13, -39,   3,  10, -34, -19,   6,  32,  44;
/M: SY='E';  M=  13, -58,  34,  50, -39, -28,   1, -62,   6, -47, -36,  23,  -2,  26,  12,   8, -32, -62, -96, -19;
/M: SY='W';  M= -36, -38, -39, -25,  15, -50, -86,  47, -59,  40,  27, -14, -67,  -7, -46, -26, -14,  10,  56,  -2;
/M: SY='H';  M= -24, -53,   5,  24,  10, -39,  32,   7, -43,   7,   3,  11, -20, -17,  27, -11, -23,  -5,   7,  27;
/M: SY='R';  M=   0,  -7,  16,  17, -29, -32,   0, -18,  10, -11, -34,  20,  -3,  30,  32,  -3,   2, -29, -37, -29;
/M: SY='E';  M=   3, -61,  40,  50, -69, -21,  -9, -44,  19, -40, -24,  -9, -16,  24,  21,   4, -28, -36, -18, -36;
/M: SY='C';  M=  23,  29,  16,   8,  -7, -20, -36, -41, -65,  -2, -22, -26,   4,  -5, -19,   9,  23,   7,  -1,  14;
/M: SY='F';  M= -14, -91, -14, -19,  66, -36,  -9, -32, -20,  24, -14, -12, -54, -31,  -6, -11, -15, -18,  59,  28;
/I:         I=-13; MD=-27;
/M: SY='P';  M=  -5, -56,  15,  11, -54,   3, -36, -22,  -3, -33, -56, -29,  43,   7,   9,  -5,   8,   3,  11,  -1; D=-13;
/I:         I=-13; MD=-27;
/M: SY='W';  M= -15, -25,   8,  28,   6, -15,   1, -32, -17, -17, -23, -30,  37,  -5,  -8,  -6, -15, -53,  37,  -5; D=-13;
/I:         I=-13; MI=-27; MD=-27; IM=-27; DM=-27;
/M: SY='Q';  M= -17, -94,  15,   1, -11, -31,   0,  -2, -13,  -3,   8, -21,  14,  34,  -8,  10, -15, -15,  14,  33; D=-13;
/I:         I=-13; DM=-27;
/M: SY='D';  M=   8, -54,  34,   6, -22,  -1,   9, -21, -11, -24, -42,  -3,  32, -12, -19,  20,   1,  -7,  18, -20;
/M: SY='E';  M=   9, -28,  13,  26, -41, -37,  17,  14,  -6, -14,   6,   4,  14,  23,   7, -23,   7, -13,   2, -60;
/M: SY='D';  M=  14, -53,  29,  28, -31, -16,   2, -58,   4, -15, -55,   6,  21,   5,  -5,  16,   9, -46, -18,  -3;
/M: SY='F';  M=  -5, -36,   0,  27,  34, -35,  -9,  -4, -33,  -8,  -7, -12, -16,   0, -24,  16,  13,  -3,   7,  22;
/M: SY='W';  M= -18, -11, -13,  -5,  27, -56,  -4,  19, -21,  20, -45, -39, -40, -29,   9,   0, -14,  -6,  58,  43;
/M: SY='R';  M=   3, -35,   7,  11, -19, -19,  20, -26,   0,   6,   8, -31,   0,  20,  33,   0,  -5, -17, -92,  -2;
/M: SY='E';  M= -12,   4,  27,  64, -54, -16,  16, -53,   7, -54, -39,   8, -27,  19,   3,  -5, -19, -31, -45,  -7;
/M: SY='W';  M= -14, -55,   0, -21,  51, -34, -22,  -5, -40,  15,   5, -84, -28,  -9,   8, -10, -38, -23,  81,  44;
/M: SY='L';  M= -24,   4,  -6,   3,   3, -27, -51,  28, -29,  31,   9, -15, -31, -25,  -4, -21, -18,  15, -43,  25;
/M: SY='E';  M=  -4, -57,  36,  50, -54, -61,  10, -36,   6, -23, -31,   4,   1,  16,   8,   5,   1, -27,  -2, -24;
/I:         I=-14; MD=-29;
/M: SY='D';  M=   6, -36,  30,  18, -16, -21,  18, -19,  -6, -28, -58,  24,  -6, -12,   9,  -7, -14, -39, -22, -35; D=-14;
/I:         I=-14; MI=-29; MD=-29; IM=-29; DM=-29;
/M: SY='W';  M=  -9, -57,  29,  40, -54,   3,  23, -76, -12, -30, -36, -10,  38,   7,  -3,  -3, -27, -43,  42,   2; D=-14;
/I:         I=-14; DM=-29;
/M: SY='P';  M= -15, -14,   5,   7, -42,  15,  21, -30,   2, -20, -54,  19,  37, -18,   2,  21,   3, -29, -38,   2;
/M: SY='H';  M=  13,   0,  13,  -2,   6,   4,  43,  -6, -13, -15,   1,   3, -40,  -5,   8,  -2, -36,  -3,  22, -12;
/I:         I=-10; MD=-22;
/M: SY='F';  M= -41, -60, -12, -24,  26,  20,   7,  -2, -12,   0, -21, -28,  -1,  -8,  25,  -1,   9, -19, -22,   6; D=-10;
/I:         I=-10; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='F';  M=  -2,  26, -55, -57,  52, -33,  27,  -4, -49,  13,   0, -20,   0, -30, -58,   8, -22,  -7,  34,  26; D=-10;
/I:         I=-10; DM=-22;
/M: SY='W';  M= -14, -54, -98, -93,  60, -22, -36,  16, -72,  32,  -2, -54, -70, -63, -31, -72, -53,  11,  81,  46;
/M: SY='V';  M=  12,-105, -74,-101,   5, -12, -71,  95,-105,  27, -13,-132,-183, -75,-139, -71, -13, 111,-184, -42;
/M: SY='A';  M=  61, -24, -44, -39, -47, -21, -32,  17, -32,   3,   8, -49, -41, -26, -20, -23, -27,  18,  14,  -1;
/M: SY='E';  M= -20, -13, -10,  57,  14, -56, -76, -26,  14, -16, -23,  -4, -33,  -6,  11, -16, -17,  -3,  31,  28;
/M: SY='D';  M= -18, -55,  35,  34, -24, -55,  19,   4,  17,  -1, -31, -22, -40,  -7,  14,  -3, -29,  -4, -16,  21;
/M: SY='D';  M= -26, -94,  73,  38, -98,  19, -10, -96,  -7, -47, -58,  47,  -6,  10, -36, -14, -43, -93,-104, -87;
/M: SY='G';  M= -43, -93,  40,  18, -71,  67,  -8, -98, -17, -66, -88,  34,  -7,  -5, -29, -15,  -8, -77, -15, -88;
/M: SY='E';  M= -20, -26,   1,  47, -54, -86,   4, -38,  43, -61, -81,  13, -48,  39,  22,  -8,  16, -13, -97, -43;
/M: SY='I';  M=  -5,   1, -56, -58,  -2, -96, -56,  49, -59,  37, -29, -67,  34, -47, -73, -84, -41,  44, -91, -10;
/M: SY='V';  M=  21, -21, -72, -91, -48, -94, -95,  56, -60,  -2,   1, -65, -30, -47, -91, -57, -25,  70, -97, -55;
/M: SY='G';  M=  22, -92, -40, -70, -99,  97, -88,-103, -85, -85, -90, -69, -47, -83, -92, -33, -82, -95, -35, -93;
/M: SY='F';  M=  -2,  45, -90, -58,  57, -19,  25, -31, -48,  -7,  38, -60, -68, -28, -44, -27,  24,  -5,  30,  52;
/M: SY='I';  M=  42,   9, -93, -89, -37,   5, -57,  49, -70,  14, -25, -64, -91, -61, -70, -36, -14,  39, -14, -41;
/M: SY='R';  M=  10,  15, -38, -12, -41,  19, -23,  -5, -33,  -7,  20, -10, -48,  17,  32,  12,  11,  -5,  10, -42;
/M: SY='L';  M=   3,  30, -55, -73,  36,  10, -54,  26, -88,  38, -18, -64, -66, -87, -46, -41, -25,  12, -12,  34;
/M: SY='Y';  M= -31, -56,  -7,  -2,   2, -22,  29, -15,   9, -15, -22,  19, -88,  -7,  26,  19,   2,   5,  16,  33;
/M: SY='P';  M= -15, -62, -21,  -6,   2, -25,  -3,  18,  14,   1,  13,   0,  42,   0,  -4, -22, -16,   8, -15,  -5;
/M: SY='D';  M= -21,   5,  26,  -4,   1, -31,   7,  23, -28,   1, -15,  26,   4,   0,   4, -20,  -5,  -1, -28,   8;
/I:         I=-12; MD=-25;
/M: SY='W';  M= -32, -97,  44,  -7, -18,  16,  15, -50, -31, -22, -31,  17,  33,  -1,  -3, -15, -15, -43,  55,  22; D=-12;
/I:         I=-12; MD=-25;
/M: SY='H';  M= -42, -66,  17,  16, -15,  11,  34, -41,  16, -34, -57,  28,  11,  17,   9,  -9,   2, -64,   8, -24; D=-12;
/I:         I=-12; MI=-25; MD=-25; IM=-25; DM=-25;
/M: SY='H';  M= -31,   9,  -8,  18,  -8, -17,  51, -11, -18, -18, -21, -19, -39, -18,  18, -24,  14,  14,  21,  16; D=-12;
/I:         I=-12; DM=-25;
/M: SY='A';  M=  36,  21, -57, -47, -50,  32,  -8,   3, -36,   6,  -9, -36, -42, -60, -17, -39,  10,   7,  25, -17; D=-12;
/I:         I=-12; DM=-25;
/M: SY='Y';  M=  10, -21, -42,  38,  17, -10,  49, -16, -19, -39, -52, -59, -30,   1, -17, -15, -10, -17,  36,  58;
/M: SY='I';  M= -60, -39, -46,  14, -27, -50, -54,  73, -69,  39,  16, -32, -92, -84, -91, -87, -61,  22, -15, -21;
/M: SY='H';  M= -10,  -1,  15,  38,   0,   5,  46,  10, -34, -18,  -7, -23, -87, -24, -18,  -5,  -6, -10,  31,  15;
/M: SY='D';  M=  11, -19,  32, -24,   0,  27,  -3, -62, -20, -31,  -3,  -2, -26, -24,  31,  22,   0, -49,  -1,   2;
/M: SY='I';  M= -58,  -5, -75, -95,  31,-100, -88,  52, -92,  45,  25, -93, -96, -90, -92, -32, -38,  37,  11,  23;
/M: SY='W';  M=  47,   6, -47, -25,  30,  -7, -34, -10, -82, -10, -11, -64, -91, -81, -17, -19, -44,  19,  55,  48;
/M: SY='V';  M= -38, -85, -99, -94, -18, -82, -99,  33, -73,  -3, -17, -93, -94, -92, -93, -67,   0,  90, -42, -76;
/M: SY='H';  M=  20, -25,  48, -21, -42, -24,  53, -29,  -3,  -3,  -8,  -5, -58, -31,  16,  27, -31, -34, -98, -23;
/M: SY='P';  M= -10, -99, -35,  35, -98, -53, -50, -74,  19, -71, -65, -48,  96,  -4,  18,   0, -42, -70, -96, -91;
/M: SY='D';  M=  16, -90,  46,  45, -69,  -8, -10, -76, -10, -48, -38,  21, -10, -22,   0,  29,   2, -55, -20, -85;
/M: SY='Y';  M=  -1,  12, -86, -27,  44, -64,  67, -29, -81, -15, -19, -82, -59,  -3, -24, -27, -44, -29,  40,  90;
/M: SY='R';  M= -53,-100, -79, -23, -43, -77,  -1, -94, -13, -51, -79, -57, -90,  71,  97, -75, -31, -63,  45, -76;
/M: SY='G';  M= -54, -24, -33, -79, -95,  74,   0, -97,  11, -71, -86,  15, -88, -15,  56, -14, -64, -32, -36, -87;
/M: SY='Q';  M= -53, -20, -76, -28, -48, -55,  25, -60,  59,  -8,  20,   1, -87,  64,  54, -27, -37, -62, -92, -44;
/M: SY='G';  M= -48, -94, -81, -89, -99, 100, -54, -84, -25,-102, -91, -32, -86, -35, -25, -25, -67, -99, -92, -93;
/M: SY='I';  M= -25, -90, -99, -94,   4, -81, -35,  67, -79,  42, -27, -93, -67, -65, -62, -69, -61,  33, -40,  44;
/M: SY='G';  M=  48, -52, -83, -88, -96,  88, -88, -66, -85, -94, -16, -55, -85, -82, -91, -34, -41, -47, -92, -92;
/M: SY='T';  M= -12, -88, -61, -14, -35, -26, -31, -70,  46, -59, -64, -53, -67,   3,  44,  43,  54, -38, -41, -58;
/M: SY='R';  M=  31, -90, -49,  21, -40, -61,   9, -18,  27, -14,   7, -24, -85,  33,  43, -20,   3, -22, -35, -23;
/M: SY='L';  M=   4, -52,-100, -92, -62, -68, -86,   1, -93,  82,  32, -96, -98, -86, -91, -60, -78,  -8, -90, -53;
/M: SY='M';  M=  -6, -36, -99, -73, -21, -78, -54,  33, -73,  53,  72, -68, -95, -63, -90, -86, -44,  36,  21, -11;
/M: SY='Q';  M=  -1, -93,  24,  41, -55, -41, -14, -55,  24, -43, -25,  32, -84,  47,  35, -10,  -6, -72,  -9, -23;
/M: SY='H';  M=  34, -28, -39,  23,  -2, -47,  41, -37,  26, -16, -33, -19, -49,  12,   9, -36,  12, -33,  10,  18;
/M: SY='A';  M=  50,  15, -69, -88, -25, -32, -89,  17, -88,  46,  -9, -89, -93, -85, -69, -38, -49,  34, -92, -27;
/M: SY='E';  M=  -6, -21, -42,  52, -47, -94, -83,  46,  -5,  26,  13, -83, -62,  -3, -19, -49, -28,  11, -93, -34;
/M: SY='E';  M=  -3, -34,  44,  55, -48, -53,  24, -64,  26, -90, -16, -12, -82,  40,  20,  -7, -11, -60, -98, -43;
/M: SY='W';  M= -14, -94, -23,   5,   9, -75,  33,  15,  15, -13,  -7, -36, -90,   3,  12, -24, -12, -12,  77,  56;
/M: SY='A';  M=  68,  31, -87, -50,  -7,   0, -27, -37, -66,  16,  27, -47, -49, -80, -68, -12, -21, -20, -90,   1;
/M: SY='R';  M=  -7, -93, -14,   3,  26, -40, -31, -14,  38, -10, -14, -32,   5,  15,  56, -34, -31, -18, -39, -53;
/M: SY='E';  M=   5, -42,  28,  45, -53,  -3,  21, -73,  21, -41, -41,  19, -37,  32,   8,   5,  -8, -63, -37, -58;
/M: SY='R';  M=  -5, -21,  -2,  26, -31, -28,  19, -17,   9,   8,   6,  -8, -31,  26,  42, -17, -30, -23,  19, -32;
/I:         I=-10; MD=-22;
/M: SY='G';  M= -44, -60, -24, -19, -18,  71,  22, -93, -23, -17, -15,  16, -24,  -4, -30, -12, -39, -58, -41, -27; D=-10;
/I:         I=-10; MD=-22;
/M: SY='C';  M=  13,  62, -49, -63,   8, -48, -25,  18, -39,  11, -32, -72,-104, -68, -33, -61, -33,   2, -37,  16; D=-10;
/I:         I=-10; MI=-22; MD=-22; IM=-22; DM=-22;
/M: SY='R';  M= -34, -16,   9,  24, -59,  -3,  25, -54,  25, -82, -55,   6,   0,   5,  27,   8,  11, -56,-102, -47; D=-10;
/I:         I=-10; DM=-22;
/M: SY='R';  M=  -7,   9, -78,  23,  -8, -23, -32, -19,  24, -30, -15, -13, -50, -31,  57,   0,   1, -24,  -1,   1; D=-10;
/I:         I=-10; DM=-22;
/M: SY='I';  M= -14, -35, -47, -77,   2, -97, -89,  53, -41,  31,  28, -54, -52, -46, -28, -34, -26,  43, -11,   1; D=-10;
/I:         I=-10; DM=-22;
/M: SY='Y';  M=  -2, -92, -24,  30,  20, -14,  16,  -8, -20, -25,  15, -37, -29,  -7, -12,   4,  12,  -3,  31,  38; D=-10;
/I:         I=-10; DM=-22;
/M: SY='L';  M=  18,  -8, -94, -49,  -1, -48, -52,   9, -70,  63, -25, -52, -52, -84, -57,  -3, -20,  -3,  49, -42;
/M: SY='W';  M= -30,  -4,  29,  31,   3,  -8,  40,  -7,  -8,  -2, -19, -30, -87,  -4, -41, -10,   2,  -6,  56,  13;
/M: SY='V';  M=  12,  35, -89, -57, -47, -74, -92,   8, -85, -11, -37, -82, -25, -86, -72, -22,  59,  65, -23, -42;
/M: SY='E';  M=   0, -92,  17,  24,  11,   4,   6, -36, -31, -15,  22, -11, -38,  23,  21,   1,  -2, -43,  -1,  18;
/M: SY='P';  M=  26, -17,  -5,  29, -32, -28,   2, -46,   7, -18, -57, -12,  41, -17, -31,   0,  11,  15, -13, -83;
/M: SY='D';  M= -19, -92,  51,   8, -33,  -3,  32, -52,   8, -54, -58,  21, -36,  22,  -3,  24,  13, -47,  39, -23;
/M: SY='N';  M= -42, -46,   0, -38, -66, -36,  -1, -58, -40, -37, -36, 108, -30,  -4, -13, -24, -10, -38,-106, -39;
/I:         I=-6; MI=0; MD=-12; IM=0; DM=-12;
/M: SY='Q';  M= -15,-106,  -9,   8, -18, -60,   0, -14,   5,  -9, -41, -51, -21,  14,  -1, -39,  -6, -17,-105, -14; D=-6;
/I:         I=-6; DM=-12;
/M: SY='P';  M=  15,-100, -30, -16, -52,  -2,  20, -55,   8, -52, -22, -12,  38,  -4,  28, -12, -31, -29, -19, -22; D=-6;
/I:         I=-6; DM=-12;
/M: SY='A';  M=  72, -35, -55, -56, -94, -35, -89, -40, -68, -24, -15, -36, -29, -32, -59,  36, -48, -36,-101, -92; D=-6;
/I:         I=-6; DM=-12;
/M: SY='I';  M= -25,   9, -89, -18, -39, -67,   7,  51, -31,   2,  16, -34, -67,  24,  34, -26, -29,  18, -95, -14; D=-6;
/I:         I=-6; DM=-12;
/M: SY='R';  M=  19, -94,  -2,  -2, -74,   9,  44, -53,  18, -74, -84,  26,  10, -24,  46,   4, -64, -54,  -1, -24; D=-6;
/I:         I=-6; DM=-12;
/M: SY='F';  M=  -9, -11, -60, -62,  79, -67, -51, -28, -58,  47,   9, -93, -99, -70, -70, -71, -23,   9, -77,   2; D=-6;
/I:         I=-6; DM=-12;
/M: SY='Y';  M= -24, -57, -92, -92,  39, -95, -10, -30, -86, -13,   0, -71, -74, -62, -84, -85, -46, -53,  44, 118; D=-6;
/I:         I=-6; DM=-12;
/M: SY='E';  M=   9, -95, -36,  63, -69, -53,  23, -73,  27, -22, -35, -36, -48,  43,  25, -34, -14, -42, -95, -24; D=-6;
/I:         I=-6; DM=-12;
/M: SY='K';  M=  -9, -58, -22, -23, -95, -38,  -1, -95,  69, -93, -53, -19, -63,  -4,  63,  22, -34, -53, -39, -56; D=-6;
/I:         I=-6; MI=0; MD=-12; IM=0; DM=-12;
/M: SY='M';  M=  -2,  40, -71, -59,  35, -78,   5,  -9, -48,  44,  44, -11, -97,  10,  -9, -35, -65,  -4, -40, -20; D=-6;
/I:         I=-6; DM=-12;
/M: SY='G';  M= -72,-190, -55, -85,-201, 198, -73,-149,-102,-205,-185, -31,-127,-166,-184, -87,-169,-200, -73,-189; D=-6;
/I:         I=-6; DM=-12;
/M: SY='F';  M= -38, -91, -74, -75, 108, -70, -49, -57, -52, -37,  10, -92,-101, -95, -68, -71, -66, -38,  14,  63; D=-6;
/I:         I=-6; DM=-12;
/M: SY='Q';  M=  -5, -24, -21,  38, -57, -49,  18, -27,  27, -60, -23, -23, -18,  39,  35,  -6,  25, -15, -95, -23; D=-6;
/I:         I=-6; DM=-12;
/M: SY='R';  M= -26, -43,  -8,  27, -19, -21, -21,  25,  11,   2, -22, -38,  -8, -15,  36, -33,  -6,  11, -91,   5;
/I:         I=-13; MD=-27;
/M: SY='E';  M=  -5, -25,  16,  47, -35, -14,  -2,   1, -23, -33,  -8, -12,   8,  -4, -19,  -5,   7,  11, -42, -13; D=-13;
/I:         I=-13; MD=-27;
/M: SY='G';  M=  -8, -21,   6,  22, -54,  51,  -4, -19,  19, -90, -53, -29,  13, -24, -15, -13,  -1, -12, -16, -45; D=-13;
/I:         I=-13; MI=-27; MD=-27; IM=-27; DM=-27;
/M: SY='R';  M= -13, -11, -10,   7,   7, -28,  -2,   0,   1, -23, -10, -12,  -5,  11,  30,  -5,  -4,  14, -37,  24; D=-13;
/I:         I=-13; DM=-27;
/M: SY='Y';  M= -20, -31,  13,  -6,  31, -12,   7,  -5, -39,  18,   7, -47, -30, -47,   5, -20, -23,  16,  21,  38;
/M: SY='R';  M= -10, -23, -20,  15,   3, -17, -19, -35,  26, -22,  33, -17,  27, -12,  37, -15, -25, -16, -44,  21;
/M: SY='K';  M= -40, -33,  21,  25,   2,  14,   7, -51,  25, -10, -10,  21, -23,  -1,  11, -13,   5, -23, -14, -31;
/M: SY='Y';  M= -16,  -2, -26, -23, -16,   6,  22,   3, -15, -14,  -3, -16,  17, -22, -28, -47,  -9, -11,  61,  73;
/M: SY='Y';  M= -10,   0,   5,   9, -16, -23, -10,   8,   4,  -9, -22, -13,  -6, -26,  22, -39,  -9,  -1,  12,  57;
/I:         I=-10; MD=-22;
/M: SY='P';  M= -12, -32, -41,   8,   0,  11,  23, -11, -17,  15,   5, -13,  34, -25,   6,  -3, -35, -20,   1,   6; D=-10;
/I:         I=-10; MD=-22;
/M: SY='H';  M= -40, -56,  31, -17, -24,  -2,  40,   1,   3, -28,  -5,  15,  -1, -43, -10, -17,   5, -14,  31, -23; D=-10;
/I:         I=-10; MI=0; MD=-22; IM=0; DM=-22;
/M: SY='A';  M=  37, -51,   8,   4, -19,   3,  32, -70, -14, -52,   8, -14, -13, -28, -26,  -5,  -4, -29, -34, -57; D=-10;
/I:         I=-10; DM=-22;
/M: SY='Y';  M= -30,   4, -40, -56,  29, -47, -83,  29, -28,  30, -10, -36, -62, -30, -33, -67,  -3,  34,  10,  50; D=-10;
/I:         I=-10; DM=-22;
/M: SY='Y';  M= -27, -28, -12,  13,  -8, -36, -27,   6, -29,  15, -27, -35,  18, -27,  12,  -4, -17,  12,  42,  49;
/M: SY='M';  M= -16, -49, -16,   3,  -6, -51, -16, -15,  -1,  21, 100, -24, -24, -75, -40, -44, -43, -24,  28,  31;
/M: SY='K';  M=  14, -50, -16,  16, -13,  -3, -12,   5,  20, -17, -26, -16, -19,   4,  16,   9,  -4,  -8,   3,  -3;
/M: SY='K';  M= -33,  14, -23, -25,   3, -74,   5,  11,  47,  23,  20, -25, -23,   6,   8, -36, -30,  -7,  -7,  13;
/M: SY='P';  M= -16, -91,  12,   2,   4, -40, -26, -46,  13,  -2,   9,  16,  34, -11,   8,  -3,  31, -47,   5,  17;
/M: SY='L';  M=   9,   5, -19, -42,   1, -29, -28,  22, -14,  37,  34, -18, -28, -25,   2, -64, -21,   9,   5,  -2;
/M: SY='P';  M= -11, -25,  28,  33, -87,  -8, -19,  -8,   4, -34, -42,   5,  37,   5,  10, -11,   9, -19, -25,   1;
/I:         E1=0; IE=-105; DE=-105;

» more

Post-processing [info]

COMPETES_HIT_WITH

PS51187; PS51191; PS51729; PS51730; PS51731

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	740 in 668 different sequences
Number of true positive hits	739 in 667 different sequences
Number of 'unknown' hits	0
Number of false positive hits	1
Number of false negative sequences	77
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	99.86 %
Recall (true positives / (true positives + false negatives))	90.56 %

Comments [info]

Taxonomic range [info]	Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	3
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	PS_Langendijk_Genevaux
Feature key [info]	DOMAIN
Feature description [info]	N-acetyltransferase
Version [info]	8

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	667 sequences AAAT_ECOLI (P46854), AAC2_MYCBO (P0A5N1), AAC2_MYCFO (Q49157), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	77 sequences BUT82_GIBZE (I1RV22), GNAT5_ARATH (Q9LR91), HAT11_DICDI (Q86J12), » more
UniProtKB/Swiss-Prot False positive sequences	1 sequence Y9628_DICDI (Q55DK2)
PDB [Detailed view]	342 PDB 1B6B; 1BOB; 1CJW; 1CM0; 1GHE; 1I12; 1I1D; 1I21; 1IB1; 1J4J; 1KUV; 1KUX; » more