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PROSITE entry PS51182


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51182
Entry name [info] C2_TENSIN
Accession [info] PS51182
Entry type [info] MATRIX
Date [info] 01-FEB-2006 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51181
Associated ProRule [info] PRU00589

Name and characterization of the entry

Description [info] C2 tensin-type domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=130;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=125;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.2453599; R2=0.0054778; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=17524.1953125; R2=7.9445629; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1325; H_SCORE=28051; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=960; H_SCORE=25151; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-14; D=-60; I=-60; B1=-300; E1=-300; MI=-205; MD=-205; IM=-205; DM=-205;
...
» more

Post-processing [info]

PROMOTED_BY PS51181

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 38 in 38 different sequences
Number of true positive hits 38 in 38 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.44 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Author [info] N_Hulo
Version [info] 7

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
38 sequences

AUXI_BOVIN  (Q27974), AUXI_HUMAN  (O75061), AUXI_MOUSE  (Q80TZ3), 
» more

UniProtKB/Swiss-Prot
False negative sequences
1 sequence

PTEN_CAEEL  (G5EE01)

		
PDB
[Detailed view]
9 PDB

1D5R; 3N0A; 5BUG; 5BZX; 5BZZ; 7JTX; 7JUK; 7JUL; 7JVX