PROSITE entry PS51181

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51181
Entry name [info]	PPASE_TENSIN
Accession [info]	PS51181
Entry type [info]	MATRIX
Date [info]	01-FEB-2006 CREATED; 12-AUG-2020 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51181
Associated ProRule [info]	PRU00590

Name and characterization of the entry

Description [info]

Phosphatase tensin-type domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=175;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=170;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=-0.7977655; R2=0.0037671; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=4642.9262695; R2=22.2597980; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=3132; H_SCORE=74361; N_SCORE=11.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=1407; H_SCORE=35962; N_SCORE=4.5; MODE=1; TEXT='?';
/DEFAULT: M0=-17; D=-20; I=-20; B1=-200; E1=-200; MI=-105; MD=-105; IM=-105; DM=-105;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-105; BD=-105;
/M: SY='R';  M= -31,   1, -29,  -6,  20, -40,  21, -20,  21, -30, -25,  -7,  25, -17,  55, -26, -10,  -5, -33,  17;
/M: SY='R';  M= -31,  29,  -9,  -3,  -3, -42,  24,  -4,  20, -29,   2, -22, -39, -13,  68, -26, -11, -29, -36,  15;
/M: SY='Y';  M=  -7, -41,  28, -25,  20, -37, -18,   7,   6,   0, -18,  -1, -40, -25, -26, -16, -11,  -8, -18,  69;
/M: SY='Q';  M= -24, -41, -20,   2, -42, -31, -22,  -8,  12, -36, -28,  29,  37,  47,  23,  14,  19, -31, -45, -32;
/M: SY='H';  M=  -5, -40,  -2,  22, -13, -15,  42, -19,  26, -18,   7,  22, -33,  12,   7,   5, -22, -32, -39,  12;
/M: SY='D';  M=  -1, -40,  45,   9, -14, -14, -23, -15, -14,  -3,  -5,   9,  27,   8, -28,  12,  -5, -29, -42,   1;
/M: SY='G';  M=  -5, -40,  10,  29, -14,  64, -27, -48, -24, -45, -38,  25, -31, -21, -32, -15, -11, -43, -42, -36;
/M: SY='F';  M=   2, -35, -41, -36,  54, -40, -31,  -1,  -5,  27, -11, -35, -42, -34, -32, -10,   7,  13, -24,  27;
/M: SY='D';  M= -27,  15,  72, -11, -38,  10, -22, -35,  -8, -15, -33,  19, -35, -22, -10,  -5,  -7, -11, -52,  -3;
/M: SY='L';  M= -33, -35, -50, -42,  27, -51, -32,   1, -43,  69,   4, -48, -50, -37, -40, -42, -29,  -7, -30,   4;
/M: SY='D';  M= -33, -46, 101,   4, -53, -30, -19, -52, -20, -50, -49,   0, -32, -20, -29, -21, -23, -48, -69, -36;
/M: SY='L';  M= -32,   4, -50, -42,  -8, -51, -34,  18, -43,  68,  33, -47, -48, -36, -40, -42, -28,  -4, -37, -19;
/M: SY='C';  M=  11,  49, -28, -28, -34, -26, -33, -21, -27, -29, -26, -18, -32, -25, -33,  49,  47,  18, -51, -33;
/M: SY='Y';  M= -36, -47, -36, -37,  14, -43,  -3,  -8, -30, -18, -15, -37, -48,  -4, -27, -31, -31, -25,   6, 110;
/M: SY='I';  M= -26, -39, -50, -47, -16, -54, -51,  73, -43,   0,  -3, -42, -41, -42, -46, -36, -21,  51, -43, -24;
/M: SY='T';  M=  -5, -29, -25, -27, -28, -34,  24, -21, -25,   6, -19,  -5, -28, -27, -31,  -6,  80, -16, -50, -15;
/M: SY='D';  M= -29, -47,  69,  15, -49, -31, -23, -42, -19, -46, -40,   2,  62, -20,   2,   2, -21, -25, -55, -38;
/M: SY='N';  M= -29, -41, -14, -17, -42, -29,  41, -44,   7, -42, -30,  65, -37,  27,  59, -17,  -6, -42, -50, -28;
/M: SY='I';  M= -26, -37, -48, -44, -14, -50, -44,  58, -42,  35,  -1, -42, -43, -38, -43, -13, -22,  40, -42, -23;
/M: SY='I';  M= -30, -42, -46, -15, -14, -54, -47,  78, -41,  20,  -1, -41, -40, -37, -45, -38, -24,  20, -40, -22;
/M: SY='A';  M=  61,  11, -37, -30, -33, -24, -39,  10, -32, -22, -20, -32,   3, -30, -36, -14,  -7,  28, -44, -34;
/M: SY='M';  M= -24,  65, -44, -38, -21, -39, -25,   0, -32,  -3, 102, -31, -37, -27, -33,  -9,  12,  -4, -45, -21;
/M: SY='G';  M=  -2, -36, -26, -31, -44,  62, -31, -46, -29, -47, -38, -14,   4, -23, -35,  55, -16, -39, -43, -38;
/M: SY='F';  M= -18, -41, -44, -43,  65,   0, -25,  13, -37,  -4, -16, -37, -45, -38, -37, -32, -11, -18,  57,  65;
/M: SY='P';  M= -30, -56, -32, -21, -51, -32, -35, -39, -28, -49, -36, -37, 111, -31, -40,  -8, -23, -44, -45, -48;
/M: SY='A';  M=  47, -28, -31, -28, -35, -11, -34, -18, -28, -28, -24, -22, -32, -25, -32,  41,  20,  25, -46, -33;
/M: SY='T';  M=  -8, -34,  -4,  27, -33, -31, -27,  -9, -20,  -6,  -1,  -1, -11, -18, -10,  30,  50, -22,  13, -30;
/M: SY='G';  M= -18, -38,  -9, -26, -44,  60, -26, -47,  19, -47, -36,  38, -33, -21,  -1,  13,   4, -42, -44, -37;
/M: SY='Y';  M= -31, -41, -38, -36,  31, -44, -25,  35,  -2,   0, -12,  -3, -42, -30,   1, -30,  -2,  14,  24,  60;
/I:         I=-4; MI=0; MD=-21; IM=0; DM=-21;
/M: SY='E';  M=   1, -43, -11,  58, -17, -10,  27, -43,  17, -38, -31, -19, -27,  45,  -1,  -6, -10, -38, -42, -29;
/M: SY='S';  M=  28, -35, -29, -21, -35,   3, -26, -29,  16,   5,   1, -21, -34,  24,  19,  29,  -6, -25, -41, -30;
/M: SY='F';  M=  10,  28, -41, -34,  48, -38, -31,   1, -34,  30,  10, -15, -44,  18, -34, -18, -26,  -5,  32,   3;
/M: SY='Y';  M= -37, -47, -42, -42,  45, -44, -13,   4, -34, -16, -16, -41, -48, -32, -32, -35, -33, -23,  79,  97;
/M: SY='R';  M= -32, -48, -30, -18, -39, -43, -18, -44,  10, -20, -27, -23, -41,  -6,  96, -27, -31, -39, -41, -27;
/M: SY='N';  M= -28, -33,  -3, -23, -37, -17,  14, -40, -14, -46, -33,  99, -38, -16, -22, -10,   4, -42, -56,  -5;
/M: SY='P';  M= -22, -44,   7, -18, -46,  -8, -28, -41,   8, -46, -36, -12,  80, -21,   6,  37,  -6, -40, -46, -39;
/M: SY='I';  M= -16, -40, -40, -13,  -2, -46, -32,  37,   6,  35,  26, -36, -41, -26,  19, -34, -27,   1,  26,   2;
/M: SY='D';  M= -26, -42,  41,  38, -43,  -7, -20, -38,  26, -25, -33,  36,  -8, -12,  13,  -6, -21, -16, -49, -34;
/M: SY='D';  M= -19, -46,  74,  53, -51, -33,   5, -49, -13, -44, -40,  -9, -28,  35, -21, -20, -24, -45, -55, -34;
/M: SY='V';  M= -22, -33, -47, -42, -16, -50, -46,  28, -40,  29,  -4, -42, -44, -40, -41, -32,   2,  65, -48, -25;
/M: SY='V';  M=   8,   1, -36,  -4,   7, -39, -34,   5, -29,  13,   6, -34, -40,  10,  -9,   0, -20,  45, -40,  -1;
/M: SY='R';  M= -14, -41, -16,  26, -40, -34,   9, -38,  28, -17, -27,  29, -32,  24,  49, -18,  13, -35, -45, -30;
/M: SY='F';  M= -40, -38, -49, -46,  92, -48, -25, -14, -41,   8, -14, -42, -51, -46, -38, -38, -32, -19,  -4,  58;
/M: SY='L';  M= -33, -35, -50, -43,  36, -51, -34,  11, -44,  67,   4, -48, -49, -38, -41, -42, -29,  -5, -31, -12;
/M: SY='D';  M= -27, -39,  61,  18, -43, -29, -19, -39,  16, -40,   3,  47, -31, -15,  -4, -15,  29, -36, -56, -34;
/M: SY='T';  M=  -9, -35, -23, -10, -36, -30,   6, -14,  25, -30,   4,   1, -30,  18,  14,  32,  41,  -4, -46, -28;
/M: SY='K';  M= -30, -42, -21, -16,   0, -34,  40, -35,  49, -24,  20,  33, -35,  18,  31, -23, -24, -36, -34,  23;
/M: SY='H';  M= -35, -46, -22, -23, -17, -38, 118, -41, -25, -17, -17, -14, -38, -16, -20, -26, -33, -42, -38,  55;
/M: SY='G';  M=   0, -43,   7, -18, -17,  60,  -4, -45,  11, -44, -19, -18,  42, -26, -29,  -7, -27, -42, -41, -36;
/M: SY='D';  M=   0, -40,  41,   3, -45,  12,   6, -44,  19, -44, -36,  27,  13,  -4,  10,  16,  -6, -39, -49, -34;
/M: SY='H';  M= -29, -42,  24,  -5, -37,  20,  89, -43,  10, -13, -26,  39, -35, -16, -20, -20, -26, -43, -55, -20;
/I:         I=-6; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='W';  M= -36, -51, -46, -40,  27, -41,  13, -25, -34, -23, -23, -42, -46, -31, -34, -20, -36, -12, 125,  80;
/M: SY='W';  M= -16,  19, -31, -19, -31, -38,  25, -13,  52, -14,  47, -22, -35,  -5,  30, -26, -11, -28,  54, -22;
/M: SY='I';  M= -26, -39, -49, -46, -16, -53,  -4,  70, -42,  11,  -3, -41, -41, -40, -44, -36, -22,  47, -43, -22;
/M: SY='W';  M= -37, -48, -50, -44,  49, -44, -27,   5, -37,   0, -17, -46, -47, -36, -37, -39, -35, -10, 114,  72;
/M: SY='N';  M= -28, -34,  -1,  15, -42, -18, -10, -23, -13, -45, -34,  97, -36, -14, -22, -11, -14, -40, -59, -37;
/M: SY='F';  M= -34, -35, -50, -44,  62, -50, -34,  -2, -43,  57,  -1, -45, -49, -41, -40, -39, -12,  -1, -24,  -4;
/I:         I=-1; MD=-5;
/M: SY='C';  M= -20, 108, -42, -35, -43, -46, -38, -47,  11, -27, -35, -32, -52, -31,  43, -32, -32, -38, -57, -43; D=-1;
/I:         I=-1; MI=0; MD=-5; IM=0; DM=-5;
/M: SY='A';  M=   5,   0, -49,  -2, -59, -12, -54, -51, -45, -21, -48, -20, -60, -45,  -7, -23, -47, -27, -69, -58; D=-1;
/I:         I=-1; DM=-5;
/M: SY='E';  M= -13,   8, -15,  41, -36,   8, -24, -38, -18, -37,  -3,   4,  -3, -14, -13,  39,  29, -32, -43,   1;
/M: SY='E';  M= -23, -45,   6,  70, -48,  20, -22, -48,   7, -43, -37, -19,  -7,  12,   9,  -7, -11, -42, -44, -37;
/M: SY='R';  M= -27, -42, -23,   1, -15,  -3, -23, -21,  23, -36, -29,  16,  29, -16,  48, -19,  28, -32, -38,  10;
/M: SY='G';  M=  11,   7, -29,  -9, -27,  35, -11, -14, -17, -12, -24, -23, -11,  -3, -12,  20,  -3,   0, -34,  27;
/M: SY='Y';  M= -33, -44,  -4, -32,   6, -40,  21, -23, -11, -22, -18, -10, -43, -24, -26, -25,  12, -14,  -3,  99;
/M: SY='D';  M= -14, -42,  64,  14, -40, -17,  11, -41, -22, -28, -36,   5,  35, -19, -29,  22,  -2, -38, -50,   0;
/M: SY='P';  M=  11, -40,  28,  10, -36, -16,  11, -31, -12,  -2, -27, -21,  55, -22, -30,  17,  -1, -21, -45, -12;
/I:         I=-5; MD=-27;
/M: SY='E';  M=  -2,  -6,  10,  29, -38, -13,  -1, -34,  20,  -4, -28,   3, -31,  -7, -20,  22,  25, -30, -48, -33; D=-5;
/I:         I=-5; MI=-27; MD=-27; IM=-27; DM=-27;
/M: SY='E';  M= -27, -42,   8,  28,   4, -13,  13, -19,  28,  -2, -26,  -5,  -5, -16,   0,  13,  -8, -31, -39,  -1; D=-5;
/I:         I=-5; DM=-27;
/M: SY='F';  M= -33, -37, -48, -44,  75, -48, -34,  11, -24,   9,  15, -15, -48, -44, -38, -37, -28,  27, -20,  18; D=-5;
/I:         I=-5; DM=-27;
/M: SY='H';  M= -32, -43,  30,   0,  14, -17,  63, -21,   1, -30,   0,  38, -38,  -4, -11, -23, -25, -35, -30,  51;
/M: SY='G';  M= -22, -14,  12, -25, -37,  49,  14, -42, -11, -43, -34,  44,  12,  -2,  -9,   6, -23, -25, -42,   8;
/M: SY='R';  M= -29, -42, -22,  -9, -12, -19,   7, -20,  19, -11, -25,  40, -38,   1,  67,  -6, -24, -34, -43, -26;
/M: SY='V';  M= -22,   9, -45, -23,  10, -49, -44,  37, -38,   1,  -8, -41, -43, -12, -40, -32, -20,  65, -43,  -5;
/M: SY='S';  M=  -3,  16, -25,  12, -28, -20,  28,  13, -11,  -8, -21,  -4, -35,  13,  10,  30, -19,   2, -41,   9;
/M: SY='H';  M= -29,  22, -23,   7, -31, -38,  75, -39,  -7, -34, -25,   1, -38,  -4,  59,  -7, -11, -15, -43,  18;
/I:         I=-6; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='Y';  M= -32,  35, -43, -40,  59, -46, -23,   8, -13, -12,   6, -38, -47, -36, -15, -34, -27,  21, -12,  68;
/M: SY='P';  M= -26, -49,  -2, -27, -17,  41, -34, -18, -31, -38,  20, -28,  86, -31, -40, -25, -27, -37, -41, -38;
/M: SY='W';  M= -38, -41, -55, -47,  83, -47, -38,  14, -42,  -1,  30, -45, -47, -45, -41, -41, -34, -17,  96,   9;
/M: SY='P';  M= -31, -46,  53,   2, -36, -36, -27, -15, -14,  13,   2, -22,  67,  -1, -31, -27, -11, -29, -48, -34;
/M: SY='D';  M= -33, -46, 101,   4, -53, -30, -19, -52, -20, -50, -49,   0, -32, -20, -29, -21, -23, -48, -69, -36;
/M: SY='H';  M=-208,-243,-159,-160,-203,-213, 446,-259,-174,-205,-161,-128,-210,-141,-156,-176,-204,-257,-310,-110;
/M: SY='H';  M= -30,  27, -16, -22,   4, -28,  87, -41, -21, -35, -26,  61, -38,  17, -22,  -7,  -9, -41,  24,   6;
/M: SY='P';  M=   9, -47, -35, -24, -42, -33, -38, -22, -30, -35, -28, -38,  98, -33, -40, -26, -22,  19, -46, -42;
/M: SY='P';  M=  -7,   3, -33, -22, -50, -32, -36, -39, -29, -48, -35, -38, 109, -32, -40, -27, -24, -42, -45, -48;
/I:         I=-6; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='P';  M= -25, -44, -24,  12, -45, -33, -29, -36,  -6, -41, -32, -24,  82,  11,   3,   7,  34, -27, -46, -38;
/M: SY='F';  M= -35, -36, -51, -45,  70, -50, -33,  14, -43,  46,  16, -45, -49, -42, -41, -40, -29,   0, -21,  10;
/M: SY='N';  M=   2, -39,   5,  31, -34,   0,  -5,  -4, -20,   5, -23,  32,  16,  -4,  -9,   7, -21, -15, -46, -32;
/M: SY='L';  M= -31, -38,   4,  -1,  15, -45,  22,  23, -35,  50,  23, -34, -42, -29, -35, -15, -26,  -9, -38, -17;
/M: SY='M';  M= -30, -37, -50, -44,   3, -50, -36,  47, -41,  47,  59, -43, -43, -35, -40, -40, -26,  13, -37, -18;
/M: SY='P';  M= -10, -43, -18,   0,   9, -39, -32,  15, -22,  24, -14, -34,  56,  19, -33, -10, -25, -12,  31, -23;
/M: SY='E';  M=   1, -40,   6,  30, -36, -33, -23, -11,  24,  -2,   3,  11,  12,  22,   9,   2, -14, -20, -44, -31;
/M: SY='F';  M= -13,  11, -49, -46,  64, -47, -39,  53, -42,   5,  -9, -40, -44, -43, -43, -20, -25,  15, -24,  10;
/M: SY='C';  M= -22,  81, -44, -41, -23, -45, -43,  33, -38, -10,  37, -34, -42, -39, -41, -20,  19,  44, -51, -29;
/M: SY='D';  M=  16,   7,  39,  10,  -9,   5, -23, -40,  17, -37,   1,  16, -34, -16,  33, -11, -23, -35, -45, -30;
/M: SY='D';  M= -24, -14,  61,  50, -45, -14, -21, -43,  -3, -24, -37,   6, -28, -12, -23,  22,  -6, -39, -53, -35;
/M: SY='M';  M=  18, -34, -46, -39, -19, -40, -37,  42, -36,   4,  70, -38, -39, -33, -38, -29, -21,  41, -43, -23;
/M: SY='D';  M= -14, -39,  41,   3, -35, -14,   5, -27,   3, -18, -27,  24, -35,   1,  28, -10,  15,   9, -48,  -9;
/M: SY='N';  M=   8, -37,  30,  30, -40, -10, -19, -34,   4, -21,   3,  55, -32,  -6,  -5,  -8,  -6, -21, -50, -34;
/M: SY='W';  M= -38, -52, -49, -40,  39, -42,  11, -26, -35,  -4, -22, -45, -46,  -9, -34, -39, -39, -34, 130,  67;
/M: SY='L';  M= -30, -35, -50, -42,   7, -50, -34,  19, -42,  61,  47, -46, -46, -36, -39, -40, -27,  17, -37, -17;
/M: SY='Q';  M=  -2, -39,   5,  27, -39, -16,  23, -16,  11, -20,   1,   0, -31,  38,  -1,  20,   8, -12, -46, -29;
/M: SY='Q';  M=  18, -37, -20,  26, -42,  11, -25, -34,   7, -36, -30, -19, -30,  32,  17,  30,  -3,  -6, -43, -33;
/I:         I=-2; MI=0; MD=-9; IM=0; DM=-9;
/M: SY='D';  M= -15,   7,  76,   3, -48, -28,  -5, -47,   9, -46, -40,   1,  13,   4,  -5,  18, -19, -42, -56, -35;
/M: SY='P';  M=  -8, -44,   2,  38, -43,   2, -25, -41,   3, -42, -34, -22,  61,  15,  -2,   7,   4, -38, -42,  -9;
/M: SY='K';  M= -18, -41,  13,  31, -42, -15,  12, -40,  37, -23,   0,  32, -31,  33,   4,  10, -21, -38, -45, -30;
/M: SY='N';  M=  -4, -37, -14, -22, -38, -25,  41, -37,  -8, -24, -28,  72, -39, -14,  48,  -5, -19, -20, -52, -29;
/M: SY='V';  M=   0, -32, -44, -40, -21, -45, -48,  31, -37,  -7,  -9, -38, -40, -39, -40, -26,  18,  69, -51, -27;
/M: SY='A';  M=  53, -31, -41, -34, -27, -29, -42,  33, -34,  -5, -14, -35, -37, -32, -38, -18, -19,  38, -43, -30;
/M: SY='V';  M=  42,  30, -42, -36, -26, -34, -44,  19, -36, -13, -14, -37, -40, -36, -39, -21, -18,  57, -48, -31;
/M: SY='V';  M= -24, -35, -50, -44, -15, -52, -47,  50, -42,  29,  -2, -44, -44, -41, -43, -36, -21,  59, -45, -24;
/M: SY='H';  M= -35, -46, -19, -19, -33, -36, 129, -52, -23, -34, -19,  -8, -35, -13, -17, -24, -33, -51, -69,  -2;
/M: SY='C';  M= -27, 140, -46, -47, -37, -42, -46, -44, -42, -34, -34, -33, -57, -50, -49, -29, -27, -31, -67, -47;
/M: SY='K';  M=-189,-233,-167,-126,-236,-211,-172,-239, 316,-233,-197,-146,-192,-118,  95,-172,-174,-224,-217,-195;
/M: SY='A';  M=  60, -31, -34, -30, -38,  37, -32, -30, -30, -28,  40, -25, -33, -26, -34,  -2, -21, -22, -41, -34;
/M: SY='G';  M= -14, -42, -30, -41, -48,  89, -36, -56, -35, -52, -41, -16, -34, -33, -43, -15, -34, -50, -39, -43;
/M: SY='K';  M=-189,-232,-167,-126,-236,-211,-172,-238, 317,-233,-197,-145,-192,-118,  84,-172,-174,-224,-217,-195;
/M: SY='G';  M= -14, -42, -30, -41, -48,  89, -36, -56, -35, -52, -41, -16, -34, -33, -43, -15, -34, -50, -39, -43;
/M: SY='R';  M=-201,-250,-190,-154,-228,-231,-156,-248, -71,-225,-192,-169,-226,-120, 350,-183,-197,-229,-227,-187;
/M: SY='T';  M= -13, -28, -22, -24, -35, -25, -30, -29, -22, -33, -29, -11, -26, -22, -29,  53,  75, -21, -51, -31;
/M: SY='G';  M= -14, -42, -30, -41, -48,  89, -36, -56, -35, -52, -41, -16, -34, -33, -43, -15, -34, -50, -39, -43;
/M: SY='T';  M= -21, -29, -30, -31, -24, -39, -35,  10, -28,  15,   8, -21, -31, -31, -34, -11,  75,  12, -49, -27;
/M: SY='M';  M= -25, -35, -49, -42, -15, -47, -33,  36, -37,  22,  86, -40, -40, -32, -37, -36, -23,  39, -42, -20;
/M: SY='C';  M=   6,  69, -41, -39, -24, -39, -42,  43, -36,   1, -13, -31, -40, -36, -41,   8,  16,  27, -48, -30;
/M: SY='C';  M=  -1, 120, -41, -41, -33, -36, -42,   7, -38, -27, -27, -30, -47, -40, -43,  17, -20,   2, -57, -39;
/M: SY='C';  M=  45,  85, -31, -29, -39, -21, -34, -36, -29, -36, -31, -22, -36, -26, -34,  43,   3, -25, -49, -37;
/M: SY='Y';  M= -35, -13, -43, -41,  26, -44, -16, -15, -35,   7, -14, -42, -48, -32, -33, -35, -31,   5,  84,  92;
/M: SY='L';  M= -32, -34, -50, -42,  -6, -51, -33,   3, -43,  73,  25, -49, -49, -35, -40, -43, -28,  -5, -37, -18;
/M: SY='M';  M= -28, -37, -49, -42, -13, -49, -34,  49, -37,  29,  71, -41, -41, -33, -21, -37, -24,  29, -39,  -3;
/I:         I=-6; MD=-32;
/M: SY='Y';  M=  10, -44,  -3,  -2,  -5, -18,  -5, -37,   9, -35, -30,  -8, -41, -23, -26,  16, -25, -35, -22,  68; D=-6;
/I:         I=-6; MI=-32; IM=-32; DM=-32;
/M: SY='S';  M= -23,  23, -12, -10,  11, -34, -24,   6,  -2,  19,   1, -12, -38,  12, -18,  36, -18, -19, -32,  28;
/M: SY='G';  M= -23,  -2,   9,  13, -37,  39,   2, -37,   1, -15,  20,  -4,  -1,  17,  15,   4, -25, -36, -41,  -5;
/I:         I=-6; MD=-32;
/M: SY='Q';  M= -30, -45,   1,  18,   2, -19, -23,   3,  19,   7,  -2,  -2,   6,  42, -19, -27, -27, -26, -34,  18; D=-6;
/I:         I=-6; MI=-32; IM=-32; DM=-32;
/M: SY='C';  M= -14,  82, -36, -17,  27,   8,   6,  -7, -20,  -3, -23,  -9, -43,  -6, -14,  -5, -27, -19,  46,  11;
/M: SY='P';  M= -26, -44, -11,   4, -32,  -8, -31, -15,  24,   8, -24, -26,  57,  -8,  -6,   8,  -9, -30,  56, -29;
/M: SY='T';  M= -22, -36,  -4, -23,  -5, -13,   3, -10,   7, -20,  -1,  33,  28,  -2, -24,  24,  35, -26, -42,  -1;
/M: SY='A';  M=  41, -35, -30,   4, -33,   5,   6, -25, -28,   6,  31, -28,  38, -24, -33,  -8,   1, -22, -42, -31;
/M: SY='E';  M= -27, -45,  35,  47, -42, -16,   2, -41,  28, -27, -32, -17,  20,  22,   7,  -3, -24, -31, -43, -10;
/I:         I=-5; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='E';  M=  13, -40,  31,  59, -45, -31, -21, -41,  -1, -26, -33,  -1, -27,  26,  -2,   3,  -4, -35, -47, -35;
/M: SY='A';  M=  50,   7, -31, -26, -12, -21,   6,  -7,  -8,  -6, -23, -23, -34, -22, -10,  38, -15, -19, -42, -28;
/M: SY='L';  M= -16, -37,  -8, -10, -14, -44, -29,  15, -19,  50,  43, -36, -42,  -7, -13, -16, -25,  -2, -37,   0;
/M: SY='E';  M= -20, -43,  37,  44, -34, -35, -18, -20,   2, -12, -28,   9, -32,  12,  33,   0, -23, -34, -41,  12;
/M: SY='Y';  M= -32, -40, -36, -34,  51, -41,  36,  -6, -12,  17, -14,  -6, -44, -28,   6,  -1, -27, -13,  18,  55;
/I:         I=-3; MD=-16;
/M: SY='Y';  M= -37, -42, -19, -41,  73, -45, -18, -18, -37,  -6,  25, -38, -49, -37, -35, -18, -31, -23,  -6,  76; D=-3;
/I:         I=-3; MI=0; MD=-16; IM=0; DM=-16;
/M: SY='G';  M=  12, -38, -16, -31, -44,  37, -34, -41, -10, -42,  -4,  -3, -35, -27, -11,  25,  34, -34, -50, -39; D=-3;
/I:         I=-3; DM=-16;
/M: SY='E';  M=   0, -39, -12,  49, -33, -33, -20,   1,  -4, -19,   6,  30, -30,  25,  -5,  -8,  10, -25, -41,   3;
/M: SY='R';  M=  -1, -41, -28, -17, -36, -18, -24, -17,  44, -12,  19, -21, -35,  19,  55, -22,  -2, -13, -40, -28;
/M: SY='R';  M= -32, -49, -27,   1, -42, -42, -18, -48,  10, -40, -30, -22, -40,  -5,  96, -26, -31, -42, -41, -28;
/M: SY='T';  M= -11, -31, -32, -30,  28, -33, -29, -18, -28,  -5,  57, -21,   0, -27, -32,  22,  58, -17, -39, -18;
/M: SY='R';  M=  -2, -42,  29, -14,   1, -33,  -1, -36,  40, -36, -29,  12,  -2, -14,  43, -12, -23, -19, -36,  16;
/M: SY='P';  M= -30, -42,  15, -22,  -9, -35, -23,   7,  22, -13,  19,  35,  40, -21,  12, -25, -22,   0, -38,  14;
/M: SY='G';  M= -18, -39, -23, -10, -42,  50, -25, -41,  23, -26,  -2,  18, -33,  13,   7,  27, -13, -38, -42, -34;
/I:         I=-4; MD=-18;
/M: SY='F';  M= -20, -61, -61, -29,  15, -64, -57,  -7, -57,  -9,   4, -23, -66, -56, -42, -27, -48,  -7, -59, -40; D=-4;
/I:         I=-4; MI=0; MD=-18; IM=0; DM=-18;
/M: SY='F';  M= -46, -63, -61, -62,  23,  17, -60, -50, -60, -35, -51, -50, -13, -59, -64,  -1, -24, -27, -57, -42; D=-4;
/I:         I=-4; DM=-18;
/M: SY='K';  M= -16, -45,  -5,   9, -12, -35,  11, -42,  49, -30, -30,  -1, -11,  43,  28,  -4, -25, -40, -41, -28; D=-4;
/I:         I=-4; DM=-18;
/M: SY='G';  M=  -5,   5, -32, -42, -49,  82, -38, -54, -36, -51, -41, -18, -36, -34, -44, -16, -11, -47, -42, -44; D=-4;
/I:         I=-4; DM=-18;
/M: SY='V';  M= -10, -34, -48, -43, -21, -48, -49,  26, -41,   6,  -9, -42, -44, -42, -43, -17,  -2,  69, -52, -28; D=-4;
/I:         I=-4; DM=-18;
/M: SY='T';  M= -18, -32, -20,  14, -34, -32, -28, -10,  -4, -15, -25, -15, -27,  14, -25,  28,  69, -20, -48, -30;
/M: SY='I';  M=   8, -36, -37, -36, -22, -39, -40,  63, -34,  -2, -10,  -3, -35, -13, -38,   0,  29,   9, -43, -26;
/M: SY='P';  M= -18, -51, -31, -22, -40, -33, -31, -16, -27, -17, -29,  -6, 100,   1, -37, -11, -23, -35, -41, -13;
/M: SY='S';  M= -10,  11, -21,  -5, -41, -18, -25, -40, -20, -43, -36, -12,  11, -14,  -3,  78,  -4, -33, -48, -33;
/M: SY='Q';  M= -10, -49, -19,  12, -54, -32, -14, -41,  -6, -36, -23, -16, -31, 105,  -7, -14, -27, -42, -38, -27;
/M: SY='I';  M= -27,  -2, -33,   0, -22, -18, -31,  33,  13,  30, -10,  -8, -39,  -7,  19, -10, -24,   6, -41, -26;
/M: SY='R';  M= -32, -49, -28, -15, -42, -42, -17, -48,  20, -40, -29, -21, -40,  14,  94, -26, -30, -42, -41, -28;
/M: SY='Y';  M= -37, -49, -38, -36,  22, -42,  -9, -25,  -9, -21, -19, -38, -46,  -1, -26, -32, -33, -31,  85, 101;
/M: SY='V';  M=  -7,  29, -47, -42, -18, -46, -46,  36, -40,  20,  -7, -41, -44, -39, -42, -13, -19,  60, -48, -26;
/M: SY='Y';  M=  -8, -44, -24,   2, -22,  24,  36, -40,  -6, -35, -27,   3, -37,  12,  46,  -8, -28, -38, -27,  52;
/M: SY='Y';  M= -21,  12, -35, -38,  12, -40,  -5, -23, -31, -20, -17, -35, -47, -26, -29, -10, -28, -27,   4, 108;
/M: SY='W';  M= -35, -43, -41, -36,  63, -44,  58,  -5, -34, -15, -17, -34, -45,  -1, -32, -34, -32,   7,  76,  54;
/M: SY='E';  M= -19, -44,  33,  67, -14, -11,   6, -25,  -6, -37, -34,   3, -27,  -8, -21,  -1, -24, -37, -40,  13;
/M: SY='R';  M= -12,   8,  -7,   1,  19, -37, -22,  -2,  20, -12,   3, -23, -37,  33,  35,  -2, -11, -19, -31,  20;
/M: SY='W';  M= -19, -39, -39, -37,  25, -39, -25,   9, -34,  31,  20,  -8,   0, -31, -35,   7, -11,  -9,  50,  49;
/M: SY='L';  M=   5, -36, -38, -30, -20, -42,   4,  25,  18,  35,  11, -32, -39, -26,  11, -29,  -8,  16, -41, -24;
/M: SY='K';  M= -12,  20, -19,   8, -32, -31,  21, -28,  32, -25, -27,  31, -34,  13,  27,  11,   7, -33, -39,  16;
/M: SY='Y';  M= -16, -41,   4,   9,  -2,  -6,  30,   2,  -5, -21, -23,  18,   1,  18, -10,  -2,  -2,  -5, -33,  38;
/M: SY='F';  M= -11, -39,  -9,  10,  32,   5,  -7, -28,   0, -11,  17, -23,  -3,  20, -11,  12,   5, -28, -28,  30;
/I:         E1=0; IE=-105; DE=-105;

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Post-processing [info]

PROMOTED_BY	PS51182
COMPETES_HIT_WITH	PS50054; PS50055

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.

Total number of hits	40 in 40 different sequences
Number of true positive hits	40 in 40 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	2
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	95.24 %

Comments [info]

Taxonomic range [info]	Eukaryotes
Maximum number of repetitions [info]	1
Author [info]	N_Hulo
Version [info]	7

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

40 sequences

AUXI_BOVIN  (Q27974), AUXI_HUMAN  (O75061), AUXI_MOUSE  (Q80TZ3),

CNRN_DICDI  (Q54JL7), FH12_ORYSJ  (Q7XWS7), FH13_ARATH  (Q9LVN1), 
FH14_ARATH  (Q9C6S1), FH18_ARATH  (Q9SK28), FH20_ARATH  (Q9FLQ7), 
FH3_ORYSJ   (Q7G6K7), FH5_ORYSJ   (Q84ZL0), FH6_ORYSJ   (Q6ZCX3), 
FH7_ORYSJ   (Q6K8Z4), GAK_HUMAN   (O14976), GAK_MOUSE   (Q99KY4), 
GAK_RAT (P97874), PTEN1_ARATH (Q9FLZ5), PTEN_CAEEL  (G5EE01), 
PTEN_CANLF  (P60483), PTEN_DICDI  (Q8T9S7), PTEN_HUMAN  (P60484), 
PTEN_MOUSE  (O08586), PTEN_RAT(O54857), PTEN_SCHPO  (O94526), 
PTEN_XENLA  (Q9PUT6), PTN2A_ARATH (Q9LT75), PTN2B_ARATH (Q8H106), 
TENS1_BOVIN (Q9GLM4), TENS1_CHICK (Q04205), TENS1_HUMAN (Q9HBL0), 
TENS1_MOUSE (E9Q0S6), TENS2_HUMAN (Q63HR2), TENS2_MOUSE (Q8CGB6), 
TENS3_HUMAN (Q68CZ2), TENS3_MOUSE (Q5SSZ5), TENSH_CAEEL (H2L045), 
TEP1_YEAST  (P53916), TPTE2_HUMAN (Q6XPS3), TPTE2_MACFA (Q4R6N0), 
TPTE_HUMAN  (P56180)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
False negative sequences

2 sequences

PPZA_ASPFC  (B0XUR7), SUV2_ARATH  (C8KI33)

PDB
[Detailed view]

9 PDB

1D5R; 3N0A; 5BUG; 5BZX; 5BZZ; 7JTX; 7JUK; 7JUL; 7JVX