PROSITE entry PS51178

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51178
Entry name [info]	PASTA
Accession [info]	PS51178
Entry type [info]	MATRIX
Date [info]	01-DEC-2005 CREATED; 01-OCT-2013 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51178
Associated ProRule [info]	PRU00528

Name and characterization of the entry

Description [info]

PASTA domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=67;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=67;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1051230; R2=0.0064917; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=986; N_SCORE=8.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=631; N_SCORE=6.2; MODE=1; TEXT='RR';
/DEFAULT: M0=-30; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-255; BD=-255;
/M: SY='G';  M= -12, -77,  18, -15, -89,  52, -57, -42,  40, -82, -72,  27, -76,  21,  -1, -13,  31, -71, -94, -83;
/M: SY='P';  M=  12, -67, -51,  23, -81, -69, -61,  -9,  27, -64, -60,  15,  61,  -7, -51,  13,  20,  18, -94, -79;
/I:         I=-21; MD=-53;
/M: SY='P';  M=   8, -72,   7,  39, -90, -66, -53, -76, -21, -80, -69,  10,  46,  42,   2,  36,  15, -39, -96, -82; D=-21;
/I:         I=-21; MD=-53;
/M: SY='K';  M= -61, -84, -26, -23, -81,  -2, -61, -30,  42, -80, -72,   3,  11,  25, -16,  11,   6, -14, -90,   3; D=-21;
/I:         I=-21; MI=-53; MD=-53; IM=-53; DM=-53;
/M: SY='V';  M= -14, -66, -24, -75,  14,   1, -71,  26, -12,  -9, -47, -69, -88, -72, -29,  10,  -1,  40, -72,  21; D=-21;
/I:         I=-21; DM=-53;
/M: SY='Q';  M=  16, -70, -24,  32,   6, -32, -57,   0,  20,  -9, -52, -57,   7,  33, -26, -23,  21, -13, -78,  -9; D=-21;
/I:         I=-21; DM=-53;
/M: SY='M';  M= -58, -57, -92, -35, -53, -33, -86,  47, -82,  -8,  87, -88, -93, -70, -83, -74, -53,  69, -75, -69; D=-21;
/I:         I=-21; DM=-53;
/M: SY='P';  M= -30, -83, -66, -26,-100, -15, -71, -90, -25, -86, -84, -66, 115,  -9, -67,  -7, -16, -79,-105, -97; D=-21;
/I:         I=-21; DM=-53;
/M: SY='D';  M= -32, -81,  84,   3, -31, -60,   5, -91, -16, -91, -84,  65, -76, -45, -16,  34, -48, -85,-106, -74;
/M: SY='Y';  M= -63,   7, -98, -92,  41,-101, -59,   4, -87,  31,  24, -90, -97, -81, -86, -77, -59,  61, -46,  67;
/M: SY='V';  M=  -9, -63, -70, -18, -59, -80, -61,  34,  23, -25, -44, -62, -79,  -9,  35,   4,  11,  47, -77,   9;
/M: SY='G';  M= -50, -86,  41, -58, -97,  87, -65,-103, -64, -99, -91,  23, -21,  -9, -29, -21, -26, -92, -97, -96;
/I:         I=-24; MI=0; MD=-61; IM=0; DM=-61;
/M: SY='W';  M= -64, -71, -73, -21, -54, -86, -61,   3,  24,  37,  67, -64, -84,  41,  27,  -8, -58, -44,  81, -57;
/M: SY='T';  M= -42, -63,  13,   1, -34, -62, -56, -71,  20, -76, -68,  24,  19, -46, -51,  61,  63, -63, -96, -73;
/M: SY='C';  M=  -3,  30, -78, -72,   8,   3, -68,  -1,  22,  25,  28, -69,  12, -63, -61,   2, -55,  21,  14,  13;
/M: SY='D';  M=  26, -75,  64,  37, -90,  -4, -58, -77, -19, -82, -75, -40, -11, -42,  33,   8,  12, -41, -99, -84;
/M: SY='E';  M= -20, -80,  58,  65, -19, -72, -49, -67, -20, -75, -65, -40, -72,  61, -50, -15,  12,  -4, -89, -74;
/M: SY='A';  M=  78, -49, -77, -66, -62, -54, -72, -12, -65,  -1, -46, -73, -66, -65, -73, -35, -11,  37, -80, -13;
/M: SY='R';  M=  10, -10, -56,  34, -70, -76, -55,   5,  32,   5,  40, -58, -75,  37,  45, -54, -56, -11, -84, -74;
/M: SY='Q';  M=  32, -72,   5,  38, -79, -23, -48, -76,  32, -49, -64,  15, -25,  50,   4,  -3,  -3, -67, -85, -12;
/M: SY='W';  M=   1, -71,   1,  23,   6, -74, -57,  20,   6,   0, -49,  22, -10,  22,  23, -50,  20, -27,  23, -60;
/M: SY='L';  M=  19, -59, -92, -85, -44, -36, -83,  -5, -80,  74,  13, -85, -21, -74, -81, -28, -58,  11, -77, -66;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='K';  M= -56, -86,   4,  26, -93, -26, -47, -85,  71, -83, -68, -14, -71,  47,  44,  -1,  -1, -78, -92, -79;
/M: SY='W';  M=  22, -71,  34,  10, -77,  -8, -58,  -6,  18, -38, -61,   5, -16,  13,  20,   5,  -7, -15,  49, -71;
/M: SY='L';  M=  23, -64, -62, -20, -15, -33,   0, -19,  26,  39, -39,  12, -76,  -9, -23,  22, -50, -20, -74,  11;
/M: SY='G';  M= -22, -83,  19, -63, -88,  84, -68, -27,  16, -27, -75,  15, -85, -62, -18, -52, -65, -76, -94, -91;
/M: SY='F';  M= -70, -64, -31, -92,  66,-102, -76,  43, -91,  42,   7, -90, -99, -83, -89, -82, -63,  32,  53,   9;
/I:         I=-13; MD=-33;
/M: SY='Q';  M= -58, -80,  21,  41, -37, -36, -52, -62,  35, -25, -59,  -6,   7,  53,   4, -21,  17,  -3, -90, -76; D=-13;
/I:         I=-13; MD=-33;
/M: SY='V';  M= -34, -10,  -3,  11, -57, -46, -64,   9, -35,  19, -43,   5,  37,  -5, -27, -61,  -4,  41, -77,  15; D=-13;
/I:         I=-13; MD=-33;
/M: SY='E';  M=   6, -69,  -2,  38,  -6,  11, -63,  21,  -4, -56, -11,   7, -78, -48,  -4,  -3,  15,  13, -88, -69; D=-13;
/I:         I=-13; MI=0; MD=-33; IM=0; DM=-33;
/M: SY='Q';  M= -82, -92,  -4, -13, -26, -54, -79,   7, -77, -70,   4, -78,-106,  29, -22, -42,   4,   0, -96, -14; D=-13;
/I:         I=-13; DM=-33;
/M: SY='W';  M=  -9, -91,  -2,   9, -99, -41,  -6, -84,   0, -56, -82, -69,   1,   4, -71, -22,  18, -32,  21, -89; D=-13;
/I:         I=-13; DM=-33;
/M: SY='Q';  M= -40, -86,   1,  -5, -91, -29, -68, -80, -15, -91, -81,  -2, -91,  31, -69,  30,   9, -14,-101, -15; D=-13;
/I:         I=-13; DM=-33;
/M: SY='Q';  M=   8, -84, -16,   5, -96, -10, -79, -33, -36, -48, -74, -72, -23,  18, -28,  -5, -20,   8,-107, -97; D=-13;
/I:         I=-13; DM=-33;
/M: SY='P';  M= -23, -90, -31,  25,   3, -96, -71, -37, -75, -81, -78, -76,  33,   7, -81, -65,  29, -26, -86,  14; D=-13;
/I:         I=-13; DM=-33;
/M: SY='S';  M= -17,   1,   8, -36, -22,  -9, -76, -80, -76, -90, -85,  26, -23,  -9, -82,  28,  -5, -16,-109, -88; D=-13;
/I:         I=-13; DM=-33;
/M: SY='S';  M= -36, -88,  21,  13,-107, -18, -72,-101, -31,-103, -94,  24,  12, -62, -75,  40,   0, -91,-119,-100; D=-13;
/I:         I=-13; DM=-33;
/M: SY='F';  M= -24, -68,   1,  -5,  37,   0, -65,  -7, -15, -28, -56, -13,  29, -13, -16,  20,  29,  14, -80, -54; D=-13;
/I:         I=-13; DM=-33;
/M: SY='Q';  M= -18, -68, -16,  -1, -67,   6,   3,  16,   5, -16, -52,   7, -78,  39, -25,  27,   8,  14, -83,  -9; D=-13;
/I:         I=-13; DM=-33;
/M: SY='G';  M=  -1, -79,  18,   8, -90,  59,  -4, -85,   0, -49, -76, -49,  57,   5, -60,  -6,   0, -76, -96, -85;
/M: SY='E';  M=   9, -69,  29,  41, -26, -24,  -9, -25,   8, -42, -62, -14,  19, -44, -56,  22,  26,  -1, -88, -23;
/M: SY='G';  M= -47, -85, -22, -10, -96,  94, -69, -93, -24, -96, -89,  19, -87, -66, -71, -24, -65, -34, -94, -96;
/I:         I=-30; MI=0; MD=-77; IM=0; DM=-77;
/M: SY='K';  M= -33, -70, -23, -13, -16, -77,  -4, -45,  49, -28,   5, -13, -77, -44,  34, -48,  48,  23, -71,  29;
/M: SY='V';  M= -23,  33, -96, -88, -56, -98, -96,  56, -87, -27, -31, -93, -90, -84, -88, -71, -49,  86, -81, -70;
/M: SY='I';  M= -60,   5, -16, -67, -11, -91, -64,  53,  -4,   9,   6, -11, -88,  19, -66, -34,  -4,  45, -68,  28;
/M: SY='K';  M=  20, -74,   1,  38, -84,  24, -54, -75,  48, -80, -71,  -9, -70,  -7,   3,  29, -48, -28, -89, -24;
/M: SY='Q';  M= -52, -68, -54, -30, -78, -74, -41, -20, -36, -61,  -1, -44, -72, 104,  -6,  -1,  57, -12, -80, -74;
/M: SY='S';  M= -21, -70,  40,  35, -57, -63, -45, -25, -54, -75, -69,  51, -75, -46, -61,  52,  11, -33, -71,  48;
/M: SY='P';  M= -28, -76, -75, -69, -85, -85, -79, -24, -70, -21, -65, -77, 117, -70, -76, -61, -26,  14,-100, -92;
/I:         I=-15; MD=-39;
/M: SY='P';  M=  20, -82,   0,  15, -92, -14, -58, -82,  20, -39, -70, -15,  52,  37,  31, -51, -25, -74, -98, -87; D=-15;
/I:         I=-15; MD=-39;
/M: SY='P';  M=  42, -71, -52,  37, -92, -11, -64, -76,  -4, -81, -74, -18,  54,  -9, -60,  18, -14, -34, -99, -87; D=-15;
/I:         I=-15; MD=-39;
/M: SY='G';  M= -48, -82, -56, -75, -84,  89, -66,-100, -70, -97, -89,  35, -88, -71, -76,   2,  -4, -89,  23, -14; D=-15;
/I:         I=-15; MD=-39;
/M: SY='T';  M=  -8, -65, -18,  15, -79,  -4,  -5, -65,   7, -40,  -7, -11, -72,  38, -51,  18,  72, -58, -91, -75; D=-15;
/I:         I=-15; MD=-39;
/M: SY='N';  M=   8, -70, -16,  -5, -84, -18, -57, -31,  12, -45, -64,  35, -19,  30,   0,  27,  35, -27, -96, -80; D=-15;
/I:         I=-15; MI=0; MD=-39; IM=0; DM=-39;
/M: SY='V';  M= -37, -67, -98, -91, -67,-102, -96,  23, -86,   6,   7, -89, -97, -84, -37, -34,  20,  60, -92, -81; D=-15;
/I:         I=-15; MI=0; MD=-39; IM=0; DM=-39;
/M: SY='P';  M= -31, -71,  24, -26, -72, -76, -64,  28,  36,   6, -49, -20,  40,  16, -19,  23, -20, -18, -93, -77; D=-15;
/I:         I=-15; DM=-39;
/M: SY='P';  M=  10, -75,   0,  20, -21, -30, -59,  -7,  35, -44, -64,  -8,  55, -46,  13,  -8, -20, -16, -86,  -6; D=-15;
/I:         I=-15; DM=-39;
/M: SY='G';  M=   0, -73,  12,  17, -85,  61, -65, -16, -62, -39, -70,  24,  27, -57, -69,   2,  24, -64, -96, -86;
/M: SY='T';  M= -47, -71,  38,  -1, -86,  29, -55, -73,  -6, -81, -72,  39, -74,  -9,   9,  42,  44, -28, -97, -81;
/M: SY='K';  M= -55, -75, -56,  10, -82, -77, -55,   7,  60, -63, -57, -50,  37,  41,  21, -23,  34,  -1, -91, -77;
/M: SY='I';  M= -60, -56, -92, -80, -50,-102, -86,  68, -80,  31, -24, -87, -92,  13, -80, -73, -15,  62, -80, -67;
/M: SY='T';  M= -56, -65,   0,  10,   4, -78, -62,  25,  -3, -50, -49,  27, -80,  -3,   3, -20,  51,  37,  26, -60;
/M: SY='L';  M= -67, -60,-102, -95,  11,-105, -89,  30, -90,  73, -15, -96, -94, -82, -87, -82, -61,  42, -72, -56;
/I:         I=-30; MD=-77;
/M: SY='T';  M= -61, -69, -63,  17,   7, -86, -57,  17,   9,  11,   3, -23, -83,  16,   0, -26,  36,  12, -69,  27; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='V';  M= -59, -57, -93, -87,   4, -99, -80,  41, -84,  40, -26, -85, -91, -80, -85, -68,  21,  65, -69,   8;
/I:         I=-30; MD=-77;
/M: SY='S';  M=  16, -63, -12,  -3, -72,  37, -60, -22, -25, -72, -68, -11, -73, -55, -64,  66, -39,   1, -84,   3; D=-30;
/I:         I=-30; MI=-77; IM=-77; DM=-77;
/M: SY='D';  M= -28, -74,  45,   8, -87,   0, -58, -27,  36, -77, -70,  24,  35, -15, -48,  16,  38, -33, -99, -82;
/I:         I=-30; E1=0; MI=-77; IE=-77; DE=-77;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.

Total number of hits	96 in 30 different sequences
Number of true positive hits	95 in 29 different sequences
Number of 'unknown' hits	1
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Archaea, Prokaryotes (Bacteria)
Maximum number of repetitions [info]	4
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	PASTA
Version [info]	3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

29 sequences

PBP2B_BACSU (Q07868), PBPX_STRPN  (P14677), PBPX_STRR6  (P59676),

PK1_STRTO   (Q9KIG4), PKN1_CALS4  (Q8R9T6), PKN1_COREF  (Q8FUI5), 
PKN1_CORGL  (Q8NU98), PKN2_CLOAB  (Q97IC2), PKN2_CLOPE  (Q8XJL8), 
PKNA2_BIFLO (Q8G4G1), PKNB_BIFLO  (Q8G6P9), PKNB_LACLA  (Q9CEF5), 
PKNB_MYCBO  (P0A5S5), PKNB_MYCLE  (P54744), PKNB_MYCS2  (A0QNG1), 
PKNB_MYCTA  (A5TY84), PKNB_MYCTO  (P9WI80), PKNB_MYCTU  (P9WI81), 
PKNX_STRCO  (Q9XA16), PKSC_STRCO  (Q9S2C0), PRKC_BACAN  (Q81WH6), 
PRKC_BACSU  (O34507), PRKC_STAAE  (A6QGC0), SP5D_BACSU  (Q03524), 
STKP_STREE  (Q8KY50), STKP_STRP2  (Q04J43), STKP_STRPN  (Q97PA9), 
STKP_STRR6  (Q8DNS0), Y063_BORBU  (O51090)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

UniProtKB/Swiss-Prot
'Unknown' sequences

1 sequence

Y796_METKA  (Q8TX79)

PDB
[Detailed view]

23 PDB

1PMD; 1PYY; 1QME; 1QMF; 1RP5; 2KUD; 2KUE; 2KUF; 2KUI; 2Z2L; 2Z2M; 2ZC3;
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