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PROSITE entry PS51165


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PURL: https://purl.expasy.org/prosite/signature/PS51165

Direct ScanProsite submission
General information about the entry

Entry name [info] THUMP
Accession [info] PS51165
Entry type [info] MATRIX
Date [info] 01-NOV-2005 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51165
Associated ProRule [info] PRU00529

Name and characterization of the entry

Description [info] THUMP domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=111;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=106;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.9529207; R2=0.0254916; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6118.3457031; R2=2.0186915; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=218; H_SCORE=6558; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=140; H_SCORE=6401; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: B1=*; E1=*; MM=*; II=*;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 485 in 485 different sequences
Number of true positive hits 485 in 485 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 14
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.19 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] THUMP
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
485 sequences

CDAT8_METKA (Q8TWU6), PUS10_AERPE (Q9YEN2), PUS10_ARCFU (O29113), 
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UniProtKB/Swiss-Prot
False negative sequences
14 sequences

PUS10_ACIS3 (D9PZU4), PUS10_CENSY (A0RUP0), PUS10_HALLT (B9LQ94), 
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PDB
[Detailed view]
15 PDB

2C5S; 2DIR; 3G8Q; 3TLJ; 3TM4; 3TM5; 3TMA; 3V8V; 3V97; 4KR6; 4KR7; 4KR9;
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