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PROSITE entry PS51158


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51158
Entry name [info] ALPHA_KINASE
Accession [info] PS51158
Entry type [info] MATRIX
Date [info] 01-NOV-2005 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51158
Associated ProRule [info] PRU00501

Name and characterization of the entry

Description [info] Alpha-type protein kinase domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=217;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=212;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.4194858; R2=0.0124391; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=11274.0244141; R2=10.0709181; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=570; H_SCORE=17014; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=409; H_SCORE=15393; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-400; E1=-400; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 22 in 22 different sequences
Number of true positive hits 22 in 22 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] Alpha-type protein kinase
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
22 sequences

AK1_DICDI   (Q54DK4), ALPK1_HUMAN (Q96QP1), ALPK1_MOUSE (Q9CXB8), 
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PDB
[Detailed view]
19 PDB

1IA9; 1IAH; 1IAJ; 3LKM; 3LLA; 3LMH; 3LMI; 3PDT; 4ZME; 4ZMF; 4ZS4; 5DYJ;
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