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PROSITE entry PS51085


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51085
Entry name [info] 2FE2S_FER_2
Accession [info] PS51085
Entry type [info] MATRIX
Date [info] 01-MAR-2005 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00175
Associated ProRule [info] PRU00465

Name and characterization of the entry

Description [info] 2Fe-2S ferredoxin-type iron-sulfur binding domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=89;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=84;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.8041449; R2=0.0109195; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=2220.8164062; R2=6.3996887; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=614; H_SCORE=6150; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=431; H_SCORE=4979; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-40; I=-40; B1=-200; E1=-200; MI=-35; MD=-35; IM=-35; DM=-35;
...
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Post-processing [info]

COMPETES_HIT_WITH PS51379

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 456 in 456 different sequences
Number of true positive hits 456 in 456 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 14
Number of 'partial' sequences 10
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.02 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] 2Fe-2S ferredoxin-type
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
456 sequences

ADRX_ENCCU  (Q8SV19), ADRX_YEAST  (Q12184), ADXH1_DROME (P37193), 
» more

UniProtKB/Swiss-Prot
False negative sequences
14 sequences

ETP1_SCHPO  (Q10361), FER1_AQUAE  (O67065), FER2_PEA(Q7M258), 
» more

UniProtKB/Swiss-Prot
'Partial' sequences
10 sequences

FER_ANASL   (P83156), FER_PORAE   (P18820), FER_PORPP   (P18821), 
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PDB
[Detailed view]
476 PDB

1A70; 1AWD; 1AYF; 1B9R; 1C4A; 1C4C; 1CJE; 1CZP; 1DOI; 1DOX; 1DOY; 1E0Z;
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