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PROSITE entry PS51084


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51084
Entry name [info] HIT_2
Accession [info] PS51084
Entry type [info] MATRIX
Date [info] 01-MAR-2005 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00694
Associated ProRule [info] PRU00464

Name and characterization of the entry

Description [info] HIT domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=108;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=103;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.9633796; R2=0.0157887; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=5210.1577148; R2=3.3684211; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=351; H_SCORE=6392; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=224; H_SCORE=5965; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-11; D=-40; I=-40; B1=-200; E1=-200; MI=-50; MD=-50; IM=-50; DM=-50;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 91 in 91 different sequences
Number of true positive hits 91 in 91 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 97.85 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] HIT
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
91 sequences

AP4A_MYCTO  (P9WMK8), AP4A_MYCTU  (P9WMK9), APH1_SCHPO  (P49776), 
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UniProtKB/Swiss-Prot
False negative sequences
2 sequences

APTX_SCHPO  (O74859), APTX_YEAST  (Q08702)

		
PDB
[Detailed view]
113 PDB

1AV5; 1EMS; 1FHI; 1FIT; 1KPA; 1KPB; 1KPC; 1KPE; 1KPF; 1RZY; 1Y23; 2FHI;
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