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PROSITE entry PS51072


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PURL: https://purl.expasy.org/prosite/signature/PS51072

Direct ScanProsite submission
General information about the entry

Entry name [info] MHD
Accession [info] PS51072
Entry type [info] MATRIX
Date [info] 01-JAN-2005 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51072
Associated ProRule [info] PRU00404

Name and characterization of the entry

Description [info] Mu homology domain (MHD) profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=252;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=247;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.1825593; R2=0.0087043; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=28068.0234375; R2=11.8837214; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=841; H_SCORE=38062; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=611; H_SCORE=35329; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-9; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 95 in 95 different sequences
Number of true positive hits 95 in 95 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] MHD
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
95 sequences

AP1M1_ARATH (Q9SAC9), AP1M1_BOVIN (Q2KJ81), AP1M1_HUMAN (Q9BXS5), 
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PDB
[Detailed view]
96 PDB

1BW8; 1BXX; 1H6E; 1HES; 1I31; 1W63; 2BP5; 2JKR; 2JKT; 2PR9; 2VGL; 2XA7;
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