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PROSITE entry PS51065


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51065
Entry name [info] NHR
Accession [info] PS51065
Entry type [info] MATRIX
Date [info] 01-JAN-2005 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51065
Associated ProRule [info] PRU00400

Name and characterization of the entry

Description [info] Neuralized homology repeat (NHR) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=158;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=153;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2954926; R2=0.0192815; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=322; N_SCORE=8.5; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=162; N_SCORE=5.4; MODE=1; TEXT='RR';
/DEFAULT: M0=-9; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 35 in 14 different sequences
Number of true positive hits 35 in 14 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 6
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] NHR
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
14 sequences

NEU1B_HUMAN (A8MQ27), NEU1B_MOUSE (Q0MW30), NEUL1_HUMAN (O76050), 
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PDB
[Detailed view]
3 PDB

2E63; 2YUE; 4KG0