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PROSITE entry PS51063


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PURL: https://purl.expasy.org/prosite/signature/PS51063

Direct ScanProsite submission
General information about the entry

Entry name [info] HTH_CRP_2
Accession [info] PS51063
Entry type [info] MATRIX
Date [info] 01-JAN-2005 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00041
Associated ProRule [info] PRU00387

Name and characterization of the entry

Description [info] Crp-type HTH domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=83;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=78;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.2152481; R2=0.0229581; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=4176.2836914; R2=2.1185567; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=231; H_SCORE=4666; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=144; H_SCORE=4481; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: B1=*; E1=*; MM=*; II=*;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 78 in 78 different sequences
Number of true positive hits 77 in 77 different sequences
Number of 'unknown' hits 1
Number of false positive hits 0
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 88.51 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] PS_Langendijk_Genevaux
Feature key [info] DOMAIN
Feature description [info] HTH crp-type
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
77 sequences

AADR_RHOPA  (Q01980), ANR_PSEAE   (P23926), ANR_PSEPH   (O85222), 
» more

UniProtKB/Swiss-Prot
False negative sequences
10 sequences

ARCR_STAA3  (Q2FDM8), ARCR_STAA8  (Q2FUY1), ARCR_STAAC  (Q5HCR6), 
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UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

RIFK_THEKO  (Q5JGN9)

		
PDB
[Detailed view]
115 PDB

1CGP; 1G6N; 1HW5; 1I5Z; 1I6X; 1J59; 1LB2; 1O3Q; 1O3R; 1O3S; 1O3T; 1OMI;
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