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PROSITE entry PS51059


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS51059
Entry name [info] PARP_CATALYTIC
Accession [info] PS51059
Entry type [info] MATRIX
Date [info] 01-JAN-2005 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC51059
Associated ProRule [info] PRU00397

Name and characterization of the entry

Description [info] PARP catalytic domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=234;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=229;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4492683; R2=0.0298623; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=203; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=136; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: B1=*; E1=*; MM=*; II=*;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 68 in 68 different sequences
Number of true positive hits 68 in 68 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] PARP catalytic
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
68 sequences

PAR10_HUMAN (Q53GL7), PAR10_MOUSE (Q8CIE4), PAR11_HUMAN (Q9NR21), 
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PDB
[Detailed view]
383 PDB

1A26; 1EFY; 1GS0; 1PAX; 1UK0; 1UK1; 1WOK; 2PAW; 2PAX; 2PQF; 2RCW; 2RD6;
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