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PROSITE entry PS50999


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50999
Entry name [info] COX2_TM
Accession [info] PS50999
Entry type [info] MATRIX
Date [info] 01-JUN-2004 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00075

Name and characterization of the entry

Description [info] Cytochrome oxidase subunit II transmembrane region profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=95;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=90;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.7467759; R2=0.0142222; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3934.6208496; R2=4.2706046; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=405; H_SCORE=5664; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=264; H_SCORE=5062; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-9; D=-40; I=-40; B1=-400; E1=-400; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 344 in 344 different sequences
Number of true positive hits 344 in 344 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
344 sequences

COX1_ACACA  (Q37370), COX1_DICCI  (Q2LCQ6), COX1_DICDI  (O21042), 
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PDB
[Detailed view]
140 PDB

1AR1; 1FFT; 1M56; 1M57; 1OCC; 1OCO; 1OCR; 1OCZ; 1QLE; 1V54; 1V55; 2DYR;
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