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PROSITE entry PS50995


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PURL: https://purl.expasy.org/prosite/signature/PS50995

Direct ScanProsite submission
General information about the entry

Entry name [info] HTH_MARR_2
Accession [info] PS50995
Entry type [info] MATRIX
Date [info] 01-MAY-2004 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00861
Associated ProRule [info] PRU00345

Name and characterization of the entry

Description [info] MarR-type HTH domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=133;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=128;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2798102; R2=0.0249925; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=6998.8300781; R2=7.9757175; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=505; H_SCORE=11027; N_SCORE=14.9; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=169; H_SCORE=8347; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 169 in 169 different sequences
Number of true positive hits 168 in 168 different sequences
Number of 'unknown' hits 1
Number of false positive hits 0
Number of false negative sequences 25
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 87.05 %

Comments [info]

Taxonomic range [info] Archaea, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] PS_Langendijk_Genevaux
Feature key [info] DOMAIN
Feature description [info] HTH marR-type
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
168 sequences

ADCR_STRP2  (Q04I02), ADCR_STRP6  (Q5XEA3), BADR_RHOPA  (O07458), 
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UniProtKB/Swiss-Prot
False negative sequences
25 sequences

MMPR5_MYCTU (I6Y8F7), SGRR_ECO57  (Q8XA02), SGRR_ECOK1  (A1A7B8), 
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UniProtKB/Swiss-Prot
'Unknown' sequences
1 sequence

RIFK_PYRFU  (Q8U262)

		
PDB
[Detailed view]
40 PDB

1JGS; 1LNW; 1S3J; 1Z91; 1Z9C; 2BV6; 2FXA; 3DEU; 3ECH; 3MEX; 3Q5F; 3QPT;
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