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PROSITE entry PS50994


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PURL: https://purl.expasy.org/prosite/signature/PS50994

Direct ScanProsite submission
General information about the entry

Entry name [info] INTEGRASE
Accession [info] PS50994
Entry type [info] MATRIX
Date [info] 01-OCT-2004 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50994
Associated ProRule [info] PRU00457

Name and characterization of the entry

Description [info] Integrase catalytic domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=161;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=156;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.0267998; R2=0.0160468; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=4805.0327148; R2=16.0532780; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=466; H_SCORE=12286; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=342; H_SCORE=10295; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-6; D=-30; I=-30; B1=-100; E1=-100; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 290 in 290 different sequences
Number of true positive hits 290 in 290 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] Integrase catalytic
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
290 sequences

ADPR_LACLL  (Q06715), COPIA_DROME (P04146), GIN1_BOVIN  (A4FUB7), 
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PDB
[Detailed view]
343 PDB

1A5V; 1A5W; 1A5X; 1ASU; 1ASV; 1ASW; 1B92; 1B9D; 1B9F; 1BHL; 1BI4; 1BIS;
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