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PROSITE entry PS50989


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50989
Entry name [info] COA_CT_CTER
Accession [info] PS50989
Entry type [info] MATRIX
Date [info] 01-MAY-2004 CREATED;
13-FEB-2019 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50980
Associated ProRule [info] PRU01137

Name and characterization of the entry

Description [info] Acetyl-coenzyme A (CoA) carboxyltransferase C-terminal domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=249;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=244;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2847874; R2=0.0069941; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-2381.6730957; R2=31.9687366; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=1104; H_SCORE=32912; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=603; H_SCORE=16895; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-34; D=-100; I=-100; B1=-1000; E1=-1000; MI=-255; MD=-255; IM=-255; DM=-255;
...
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Post-processing [info]

COMPETES_HIT_WITH PS50980(50)

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 530 in 530 different sequences
Number of true positive hits 530 in 530 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] CoA carboxyltransferase C-terminal
Version [info] 7

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
530 sequences

12S_PROFR   (Q8GBW6), ACACA_BOVIN (Q9TTS3), ACACA_HUMAN (Q13085), 
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UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

ACAC_CATRO  (P85438)

		
PDB
[Detailed view]
69 PDB

1OD2; 1OD4; 1ON3; 1ON9; 1PIX; 1UYR; 1UYS; 1UYT; 1UYV; 1W2X; 2A7S; 2BZR;
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