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PROSITE entry PS50987


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50987
Entry name [info] HTH_ARSR_2
Accession [info] PS50987
Entry type [info] MATRIX
Date [info] 01-MAY-2004 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00661
Associated ProRule [info] PRU00340

Name and characterization of the entry

Description [info] ArsR-type HTH domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=95;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=90;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.5284152; R2=0.0144047; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=5880.1357422; R2=5.3587360; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=491; H_SCORE=8511; N_SCORE=9.6; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=276; H_SCORE=7359; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 53 in 53 different sequences
Number of true positive hits 51 in 51 different sequences
Number of 'unknown' hits 2 in 2 different sequences
Number of false positive hits 0
Number of false negative sequences 2
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.23 %

Comments [info]

Taxonomic range [info] Archaea, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] PS_Langendijk_Genevaux
Feature key [info] DOMAIN
Feature description [info] HTH arsR-type
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
51 sequences

ARSR1_ECOLX (P15905), ARSR1_PSEPK (Q88LK1), ARSR2_ECOLX (P52144), 
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UniProtKB/Swiss-Prot
False negative sequences
2 sequences

Y229_METJA  (Q57682), Y361_METJA  (Q57807)

		
UniProtKB/Swiss-Prot
'Unknown' sequences
2 sequences

RIFK_CENSY  (A0RTV6), Y529_ARCFU  (O29721)

		
PDB
[Detailed view]
15 PDB

1KU9; 1R1T; 1R22; 1R23; 1SMT; 1U2W; 2JSC; 2ZKZ; 3CUO; 3F72; 3PQJ; 3PQK;
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