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PROSITE entry PS50979


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PURL: https://purl.expasy.org/prosite/signature/PS50979

Direct ScanProsite submission
General information about the entry

Entry name [info] BC
Accession [info] PS50979
Entry type [info] MATRIX
Date [info] 01-APR-2004 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50979
Associated ProRule [info] PRU00969

Name and characterization of the entry

Description [info] Biotin carboxylation domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=229;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=229;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=1.2670990; R2=0.0099447; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=-41140.9023438; R2=46.3007355; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=728; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=527; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-9; D=-20; I=-20; B1=*; E1=*; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 77 in 77 different sequences
Number of true positive hits 76 in 76 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 0
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 98.70 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] Biotin carboxylation
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
76 sequences

2OCS_HYDTT  (D3DJ42), ACACA_BOVIN (Q9TTS3), ACACA_HUMAN (Q13085), 
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UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

ACCC_POPEU  (P84546)

		
UniProtKB/Swiss-Prot
False positive sequences
1 sequence

PURT_SALTY  (Q8ZNW5)

		
PDB
[Detailed view]
96 PDB

1BNC; 1DV1; 1DV2; 1W93; 1W96; 2C00; 2GPS; 2GPW; 2HJW; 2J9G; 2V58; 2V59;
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