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PROSITE entry PS50949


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50949
Entry name [info] HTH_GNTR
Accession [info] PS50949
Entry type [info] MATRIX
Date [info] 01-DEC-2003 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00042
Associated ProRule [info] PRU00307

Name and characterization of the entry

Description [info] GntR-type HTH domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=69;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=64;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.3032043; R2=0.0175858; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=3951.6735840; R2=3.4856045; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=506; H_SCORE=5715; N_SCORE=12.2; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=182; H_SCORE=4586; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-50; I=-50; B0=-50; B1=-500; E0=-50; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 235 in 235 different sequences
Number of true positive hits 235 in 235 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 1
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.58 %

Comments [info]

Taxonomic range [info] Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] PS_Langendijk_Genevaux
Feature key [info] DOMAIN
Feature description [info] HTH gntR-type
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
235 sequences

AIRSR_SALTY (Q8ZKR0), ARAR_BACSU  (P96711), ARAR_GEOSE  (Q9S470), 
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UniProtKB/Swiss-Prot
False negative sequences
1 sequence

LGOR_ECOLI  (P39399)

		
PDB
[Detailed view]
28 PDB

1E2X; 1H9G; 1H9T; 1HW1; 1HW2; 2WV0; 3BWG; 3F8M; 4EGY; 4EGZ; 4H0E; 4MGR;
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