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PROSITE entry PS50943


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50943
Entry name [info] HTH_CROC1
Accession [info] PS50943
Entry type [info] MATRIX
Date [info] 01-NOV-2003 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50943
Associated ProRule [info] PRU00257

Name and characterization of the entry

Description [info] Cro/C1-type HTH domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=64;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=64;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=7.7448611; R2=0.0001141; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=314460.8437500; R2=0.5538543; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=13630; H_SCORE=322010; N_SCORE=9.3; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=-10910; H_SCORE=308418; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: B0=*; B1=*; E0=*; E1=*; MM=*; II=*;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 266 in 266 different sequences
Number of true positive hits 261 in 261 different sequences
Number of 'unknown' hits 0
Number of false positive hits 5 in 5 different sequences
Number of false negative sequences 7
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 98.12 %
Recall (true positives / (true positives + false negatives)) 97.39 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] PS_Langendijk_Genevaux
Feature key [info] DOMAIN
Feature description [info] HTH cro/C1-type
Version [info] 9

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
261 sequences

ANSR_BACSU  (Q07683), BCRR_ENTFL  (Q5WNW9), CEBA_BACAM  (P23939), 
» more

UniProtKB/Swiss-Prot
False negative sequences
7 sequences

HEPD_STRVT  (Q5IW40), HICB2_PHOLL (Q7MZD8), HIGA2_VIBCH (Q9KMA5), 
» more

UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

NADR_KLEPN  (P47981)

		
UniProtKB/Swiss-Prot
False positive sequences
5 sequences

CYNS_AQUAE  (O66587), CYNS_MEDTR  (B7FKW7), CYNS_PHANO  (Q0UBT2), 
» more

PDB
[Detailed view]
103 PDB

1ADR; 1B0N; 1LLI; 1LMB; 1LRP; 1PER; 1PRA; 1R63; 1R69; 1RIO; 1RPE; 1SQ8;
» more