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PROSITE entry PS50942


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PURL: https://purl.expasy.org/prosite/signature/PS50942

Direct ScanProsite submission
General information about the entry

Entry name [info] ENTH
Accession [info] PS50942
Entry type [info] MATRIX
Date [info] 01-NOV-2003 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50942
Associated ProRule [info] PRU00243

Name and characterization of the entry

Description [info] ENTH domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=133;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=128;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=3.0028553; R2=0.0247305; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=223; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=142; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-50; I=-50; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 60 in 60 different sequences
Number of true positive hits 60 in 60 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 93.75 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] ENTH
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
60 sequences

AP180_ARATH (Q9ZVN6), AP180_HUMAN (O60641), AP180_MOUSE (Q61548), 
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UniProtKB/Swiss-Prot
False negative sequences
4 sequences

AP4AT_HUMAN (Q96N21), AP4AT_MOUSE (Q3U3N6), AP4AT_RAT   (G3V8Y7), 
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PDB
[Detailed view]
31 PDB

1EDU; 1EYH; 1H0A; 1HF8; 1HFA; 1HG2; 1HG5; 1HX8; 1INZ; 1XGW; 2QY7; 2V8S;
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