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PROSITE entry PS50931


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PURL: https://purl.expasy.org/prosite/signature/PS50931

Direct ScanProsite submission
General information about the entry

Entry name [info] HTH_LYSR
Accession [info] PS50931
Entry type [info] MATRIX
Date [info] 01-OCT-2003 CREATED;
26-FEB-2020 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00043
Associated ProRule [info] PRU00253

Name and characterization of the entry

Description [info] LysR-type HTH domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=58;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=58;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.7633278; R2=0.0002840; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=265878.4062500; R2=1.5322067; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=21961; H_SCORE=299527; N_SCORE=9.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=13158; H_SCORE=286039; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: B1=*; E1=*; MM=*; II=*;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 434 in 433 different sequences
Number of true positive hits 434 in 433 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 0
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] PS_Langendijk_Genevaux
Feature key [info] DOMAIN
Feature description [info] HTH lysR-type
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
433 sequences

AAER_ECOLI  (P67662), ABAB_STRAT  (P52659), ABGR_ECOLI  (P77744), 
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UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

TRPI_PSEPU  (P36414)

		
PDB
[Detailed view]
30 PDB

1AL3; 2H98; 2H99; 2H9B; 3FXQ; 3FXR; 3FXU; 3FZJ; 3HHG; 3ISP; 3K1M; 3K1N;
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