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PROSITE entry PS50926


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50926
Entry name [info] TRAM
Accession [info] PS50926
Entry type [info] MATRIX
Date [info] 01-SEP-2003 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50926
Associated ProRule [info] PRU00208

Name and characterization of the entry

Description [info] TRAM domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=61;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=56;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4146850; R2=0.0275585; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=1999.7829590; R2=2.1231670; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=225; H_SCORE=2477; N_SCORE=8.6; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=149; H_SCORE=2316; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-30; I=-30; B1=-300; E1=-300; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 1'233 in 1'231 different sequences
Number of true positive hits 1'233 in 1'231 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 64
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 95.07 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] TRAM
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
1231 sequences

AMTAB_ARCFU (O29021), AMTAB_METJA (Q58277), AMTAB_METTH (O26914), 
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UniProtKB/Swiss-Prot
False negative sequences
64 sequences

MIAB_BIFLD  (B3DQX6), MIAB_BIFLO  (Q8G4H4), MIAB_BIFLS  (B7GQG0), 
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PDB
[Detailed view]
10 PDB

1UWV; 2BH2; 2QGQ; 4JC0; 5XJ1; 5XJ2; 5ZQ0; 5ZQ1; 5ZQ8; 5ZTH