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PROSITE entry PS50894


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50894
Entry name [info] HPT
Accession [info] PS50894
Entry type [info] MATRIX
Date [info] 01-FEB-2003 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50894
Associated ProRule [info] PRU00110

Name and characterization of the entry

Description [info] Histidine-containing phosphotransfer (HPt) domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=99;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=94;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4143000; R2=0.0265388; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=5289.4028320; R2=6.9194140; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=286; H_SCORE=7268; N_SCORE=10.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=154; H_SCORE=6355; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-50; I=-50; B1=-1000; E1=-1000; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 52 in 52 different sequences
Number of true positive hits 52 in 52 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 3
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 94.55 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20
Author [info] V_Lesaux
Feature key [info] DOMAIN
Feature description [info] HPt
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
52 sequences

AHP1_ARATH  (Q9ZNV9), AHP2_ARATH  (Q9ZNV8), AHP3_ARATH  (Q9SAZ5), 
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UniProtKB/Swiss-Prot
False negative sequences
3 sequences

ARUS_PSEAE  (Q9HUI3), PHP1_ORYSJ  (Q0JJE3), PHP5_ORYSJ  (Q6F303)

		
PDB
[Detailed view]
25 PDB

1A0B; 1BDJ; 1C02; 1C03; 1FR0; 1I5N; 1OXB; 1OXK; 1QSP; 1SR2; 1TQG; 1Y6D;
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