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PROSITE entry PS50890


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PURL: https://purl.expasy.org/prosite/signature/PS50890

Direct ScanProsite submission
General information about the entry

Entry name [info] PUA
Accession [info] PS50890
Entry type [info] MATRIX
Date [info] 01-NOV-2002 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50890
Associated ProRule [info] PRU00161

Name and characterization of the entry

Description [info] PUA domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=79;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=79;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=7.4500546; R2=0.0001097; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=470755.1562500; R2=1.1542819; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=9572; H_SCORE=481804; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=-8660; H_SCORE=460759; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: B0=*; B1=*; E0=*; E1=*; MM=*; II=*;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 590 in 590 different sequences
Number of true positive hits 590 in 590 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 19
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 96.88 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] PUA
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
590 sequences

ARCSA_METAC (Q8TH90), ARCSA_THEAC (Q9HJP3), ARCSA_THEKO (Q5JHG7), 
» more

UniProtKB/Swiss-Prot
False negative sequences
19 sequences

ATGT_AERPE  (Q9YAC2), ATGT_ARCFU  (O29667), ATGT_HALMA  (Q5UXP9), 
» more

PDB
[Detailed view]
72 PDB

1IQ8; 1IT7; 1IT8; 1J2B; 1R3E; 1SQW; 1T5Y; 1ZE1; 1ZE2; 2AB4; 2APO; 2AUS;
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