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PROSITE entry PS50889


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50889
Entry name [info] S4
Accession [info] PS50889
Entry type [info] MATRIX
Date [info] 01-NOV-2002 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50889
Associated ProRule [info] PRU00182

Name and characterization of the entry

Description [info] S4 RNA-binding domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=60;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=60;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=6.8325300; R2=0.0001254; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=319596.3750000; R2=0.8829120; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=13298; H_SCORE=331337; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=-2651; H_SCORE=317256; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: B0=*; B1=*; E0=*; E1=*; MM=*; II=*;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 1'871 in 1'869 different sequences
Number of true positive hits 1'871 in 1'869 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 28
Number of 'partial' sequences 1
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 98.53 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 2
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] S4 RNA-binding
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
1869 sequences

HLYA_BRAHO  (Q06803), HSLR_AERSA  (Q44264), HSLR_ECO57  (P0ACH0), 
» more

UniProtKB/Swiss-Prot
False negative sequences
28 sequences

MRES1_HUMAN (Q9P0P8), MRES1_MOUSE (Q9CQF4), PUS3_ARATH  (Q5XET6), 
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UniProtKB/Swiss-Prot
'Partial' sequences
1 sequence

RS9_PIG (Q29197)

		
PDB
[Detailed view]
1486 PDB

1C05; 1C06; 1DM9; 1EG0; 1FJG; 1FKA; 1H3E; 1H3F; 1HNW; 1HNX; 1HNZ; 1HR0;
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