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PROSITE entry PS50883


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PURL: https://purl.expasy.org/prosite/signature/PS50883

Direct ScanProsite submission
General information about the entry

Entry name [info] EAL
Accession [info] PS50883
Entry type [info] MATRIX
Date [info] 01-DEC-2002 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50883
Associated ProRule [info] PRU00074

Name and characterization of the entry

Description [info] EAL domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=254;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=249;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.6907001; R2=0.0180150; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=5668.5893555; R2=20.2724228; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=323; H_SCORE=12217; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=212; H_SCORE=9966; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-50; I=-50; B1=-1000; E1=-1000; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 45 in 45 different sequences
Number of true positive hits 43 in 43 different sequences
Number of 'unknown' hits 0
Number of false positive hits 2 in 2 different sequences
Number of false negative sequences 8
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 95.56 %
Recall (true positives / (true positives + false negatives)) 84.31 %

Comments [info]

Taxonomic range [info] Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] EAL
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
43 sequences

BLUF_ECOLI  (P75990), CDGJ_VIBCH  (Q9KVK6), CDPA_VIBCH  (Q9KVL2), 
» more

UniProtKB/Swiss-Prot
False negative sequences
8 sequences

YDIV_ECOLI  (P76204), YDIV_SALAR  (A9MFB2), YDIV_SALCH  (Q57PU2), 
» more

UniProtKB/Swiss-Prot
False positive sequences
2 sequences

ACP_HELHP   (Q7VI80), NTPP_SYNS3  (Q0IBR4)

		
PDB
[Detailed view]
16 PDB

2BAS; 2W27; 3SY8; 4HU3; 4HU4; 4KIE; 4LJ3; 4LYK; 5M1T; 7PK5; 9BGV; 9BKV;
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