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PROSITE entry PS50880


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PURL: https://purl.expasy.org/prosite/signature/PS50880

Direct ScanProsite submission
General information about the entry

Entry name [info] TOPRIM
Accession [info] PS50880
Entry type [info] MATRIX
Date [info] 01-NOV-2012 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50880
Associated ProRule [info] PRU00995

Name and characterization of the entry

Description [info] Toprim domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=96;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=91;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.2042551; R2=0.0092622; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=12173.6445312; R2=2.4526854; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=788; H_SCORE=14106; N_SCORE=9.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=464; H_SCORE=13312; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-50; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 1'123 in 1'123 different sequences
Number of true positive hits 1'123 in 1'123 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 99.65 %

Comments [info]

Taxonomic range [info] Archaea, Bacteriophages, Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] CJA_Sigrist
Feature key [info] DOMAIN
Feature description [info] Toprim
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
1123 sequences

65KD_ZYMMA  (P15255), DNAG_AERPE  (Q9YA42), DNAG_AQUAE  (O67465), 
» more

UniProtKB/Swiss-Prot
False negative sequences
4 sequences

GYRB_PROMI  (P22840), GYRB_RHOCA  (P31860), PRIH_ARATH  (F4I6E6), 
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PDB
[Detailed view]
206 PDB

1BGW; 1BJT; 1CY0; 1CY1; 1CY2; 1CY4; 1CY6; 1CY7; 1CY8; 1D6M; 1DD9; 1DDE;
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