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PROSITE entry PS50868


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PURL: https://purl.expasy.org/prosite/signature/PS50868

Direct ScanProsite submission
General information about the entry

Entry name [info] POST_SET
Accession [info] PS50868
Entry type [info] MATRIX
Date [info] 01-NOV-2002 CREATED;
07-APR-2021 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50280
Associated ProRule [info] PRU00155

Name and characterization of the entry

Description [info] Post-SET domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=17;
/DISJOINT: DEFINITION=PROTECT; N1=2; N2=16;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.1220000; R2=0.0163836; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=164.0236969; R2=0.1421801; PRIORITY=1; TEXT='Heuristic 5.0%';
/CUT_OFF: LEVEL=0; SCORE=359; H_SCORE=215; N_SCORE=8.0; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=268; H_SCORE=202; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-11; D=-20; I=-20; B0=-60; B1=-60; E0=-60; E1=-60; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_03 which contains 573'661 sequence entries.


Total number of hits 127 in 127 different sequences
Number of true positive hits 127 in 127 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 10
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 92.70 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20_shuffled
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] Post-SET
Version [info] 6

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
127 sequences

ASH1L_HUMAN (Q9NR48), ASH1L_MOUSE (Q99MY8), ASH1_DROME  (Q9VW15), 
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UniProtKB/Swiss-Prot
False negative sequences
10 sequences

ATXR3_ARATH (O23372), EHMT2_HUMAN (Q96KQ7), EHMT2_MOUSE (Q9Z148), 
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PDB
[Detailed view]
129 PDB

1ML9; 1MVH; 1MVX; 1PEG; 2O8J; 2R3A; 2W5Y; 2W5Z; 3BO5; 3K5K; 3OOI; 3OPE;
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