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PROSITE entry PS50862


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50862
Entry name [info] AA_TRNA_LIGASE_II
Accession [info] PS50862
Entry type [info] MATRIX
Date [info] 01-MAY-2002 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00363

Name and characterization of the entry

Description [info] Aminoacyl-transfer RNA synthetases class-II family profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=263;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=258;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.4519; R2=0.02101812; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=383; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=288; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-20; I=-20; B1=-40; E1=-40; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Post-processing [info]

COMPETES_SEQ_WITH PS50860

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_02 which contains 573'230 sequence entries.


Total number of hits 5'670 in 5'670 different sequences
Number of true positive hits 5'669 in 5'669 different sequences
Number of 'unknown' hits 0
Number of false positive hits 1
Number of false negative sequences 19
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 99.98 %
Recall (true positives / (true positives + false negatives)) 99.67 %

Comments [info]

Taxonomic range [info] Archaea, Eukaryotes, Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] window20_shuffled
Author [info] N_Hulo
Version [info] 4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
5669 sequences

ASNA_ACTP2  (A3N3D3), ASNA_ACTP7  (B3GZ90), ASNA_ACTPJ  (B0BT12), 
» more

UniProtKB/Swiss-Prot
False negative sequences
19 sequences

E2AK4_HUMAN (Q9P2K8), E2AK4_MOUSE (Q9QZ05), GCN2_ARATH  (Q9LX30), 
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UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

SYK_CAMUP   (Q46464), SYNC_SACPA  (P41908)

		
UniProtKB/Swiss-Prot
False positive sequences
1 sequence

CARB_XANCP  (P58943)

		
PDB
[Detailed view]
353 PDB

11AS; 12AS; 1ADJ; 1ADY; 1ASY; 1ASZ; 1ATI; 1B70; 1B76; 1B7Y; 1B8A; 1BBU;
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